3-(diphenylmethoxy)-8-methyl-8-azabicyclo[3.2.1]octane (BioDeep_00001877102)

   


代谢物信息卡片


3-(diphenylmethoxy)-8-methyl-8-azabicyclo[3.2.1]octane

化学式: C21H25NO (307.193604)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CN1C2CCC1CC(C2)OC(C3=CC=CC=C3)C4=CC=CC=C4
InChI: InChI=1S/C21H25NO/c1-22-18-12-13-19(22)15-20(14-18)23-21(16-8-4-2-5-9-16)17-10-6-3-7-11-17/h2-11,18-21H,12-15H2,1H3

描述信息

同义名列表

1 个代谢物同义名

3-(diphenylmethoxy)-8-methyl-8-azabicyclo[3.2.1]octane



数据库引用编号

5 个数据库交叉引用编号

分类词条

相关代谢途径

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代谢反应

0 个相关的代谢反应过程信息。

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INOH(0)

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0 个相关的物种来源信息

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  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

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文献列表

  • Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome. Cell reports. 2021 04; 35(4):109040. doi: 10.1016/j.celrep.2021.109040. [PMID: 33910017]
  • Kyle C Schmitt, Maarten E A Reith. The atypical stimulant and nootropic modafinil interacts with the dopamine transporter in a different manner than classical cocaine-like inhibitors. PloS one. 2011; 6(10):e25790. doi: 10.1371/journal.pone.0025790. [PMID: 22043293]
  • Erik Johnsen, Hugo A Jørgensen. Effectiveness of second generation antipsychotics: a systematic review of randomized trials. BMC psychiatry. 2008 Apr; 8(?):31. doi: 10.1186/1471-244x-8-31. [PMID: 18439263]
  • Mu-Fa Zou, Jianjing Cao, Theresa Kopajtic, Rajeev I Desai, Jonathan L Katz, Amy Hauck Newman. Structure-activity relationship studies on a novel series of (S)-2beta-substituted 3alpha-[bis(4-fluoro- or 4-chlorophenyl)methoxy]tropane analogues for in vivo investigation. Journal of medicinal chemistry. 2006 Oct; 49(21):6391-9. doi: 10.1021/jm060762q. [PMID: 17034144]
  • Santosh S Kulkarni, Peter Grundt, Theresa Kopajtic, Jonathan L Katz, Amy Hauck Newman. Structure-activity relationships at monoamine transporters for a series of N-substituted 3alpha-(bis[4-fluorophenyl]methoxy)tropanes: comparative molecular field analysis, synthesis, and pharmacological evaluation. Journal of medicinal chemistry. 2004 Jun; 47(13):3388-98. doi: 10.1021/jm030646c. [PMID: 15189035]
  • A H Newman, M J Robarge, I M Howard, S L Wittkopp, C George, T Kopajtic, S Izenwasser, J L Katz. Structure-activity relationships at monoamine transporters and muscarinic receptors for N-substituted-3alpha-(3'-chloro-, 4'-chloro-, and 4',4''-dichloro-substituted-diphenyl)methoxytropanes. Journal of medicinal chemistry. 2001 Feb; 44(4):633-40. doi: 10.1021/jm000417f. [PMID: 11170654]
  • A H Newman, S Izenwasser, M J Robarge, R H Kline. CoMFA study of novel phenyl ring-substituted 3alpha-(diphenylmethoxy)tropane analogues at the dopamine transporter. Journal of medicinal chemistry. 1999 Sep; 42(18):3502-9. doi: 10.1021/jm980701v. [PMID: 10479283]