Mivotilate (BioDeep_00001876720)
代谢物信息卡片
化学式: C12H14N2O3S3 (330.0166534)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC1=CSC(=N1)NC(=O)C(=C2SCS2)C(=O)OC(C)C
InChI: InChI=1S/C12H14N2O3S3/c1-6(2)17-10(16)8(11-19-5-20-11)9(15)14-12-13-7(3)4-18-12/h4,6H,5H2,1-3H3,(H,13,14,15)
数据库引用编号
5 个数据库交叉引用编号
- ChEBI: CHEBI:135409
- PubChem: 148185
- ChEMBL: CHEMBL3301677
- CAS: 130112-42-4
- CAS: 126164-80-5
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- Fiona Whelan, Nan Hao, Sebastian G B Furness, Murray L Whitelaw, Anne Chapman-Smith. Amino acid substitutions in the aryl hydrocarbon receptor ligand binding domain reveal YH439 as an atypical AhR activator.
Molecular pharmacology.
2010 Jun; 77(6):1037-46. doi:
10.1124/mol.109.062927
. [PMID: 20231332] - Dong-Han Han, Zhe-Hu Jin, Yan-Zhe Jin, Xue-Zhe Yin, Yuan-Yuan Shen, Zhong-Gao Gao. Thermal reversible microemulsion system for poorly water-soluble YH439 for oral delivery.
Chemical & pharmaceutical bulletin.
2010 Jan; 58(1):11-5. doi:
10.1248/cpb.58.11
. [PMID: 20045958] - Soon-Sun Hong, Hong Li, Min-Koo Choi, Suk-Jae Chung, Chang-koo Shim. Effect of a new hepatoprotective agent, YH-439, on the hepatobiliary transport of organic cations (OCs): selective inhibition of sinusoidal OCs uptake without influencing glucose uptake and canalicular OCs excretion.
Archives of pharmacal research.
2005 Mar; 28(3):330-4. doi:
10.1007/bf02977801
. [PMID: 15832822] - M K Kim, B J Song, J Seidel, Y Soh, K S Jeong, I S Kim, H Kobayashi, M V Green, J A Carrasquillo, C H Paik. Use of 99mTc-mercaptoacetyltriglycine (MAG3)-biocytin hepatobiliary scintigraphy to study the protective effect of a synthetic enzyme inhibitor on acute hepatotoxicity in mice.
Nuclear medicine and biology.
1998 Aug; 25(6):561-8. doi:
10.1016/s0969-8051(98)00019-5
. [PMID: 9751424] - S G Kim, Y J Surh, Y Sohn, J K Yoo, J W Lee, A Liem, J A Miller. Inhibition of vinyl carbamate-induced hepatotoxicity, mutagenicity, and tumorigenicity by isopropyl-2-(1,3-dithietane-2-ylidene)-2-[N-(4-methylthiazol-2- yl)carbamoyl]acetate (YH439).
Carcinogenesis.
1998 Apr; 19(4):687-90. doi:
10.1093/carcin/19.4.687
. [PMID: 9600356] - W H Yoon, J K Yoo, J W Lee, C K Shim, M G Lee. Species differences in pharmacokinetics of a hepatoprotective agent, YH439, and its metabolites, M4, M5, and M7, after intravenous and oral administration to rats, rabbits, and dogs.
Drug metabolism and disposition: the biological fate of chemicals.
1998 Feb; 26(2):152-63. doi:
NULL
. [PMID: 9456302] - W H Yoon, J K Yoo, J W Lee, C K Shim, M G Lee. Simultaneous determination of a new hepatoprotective agent, YH439, and its metabolites, M4, M5, and M7 in plasma and urine by high-performance liquid chromatography.
Research communications in molecular pathology and pharmacology.
1998 Jan; 99(1):117-24. doi:
NULL
. [PMID: 9523359] - S W Myung, S Huh, M Kim, J Park, J K Yoo, J S Chae, J W Lee. Identification of YH439 and its metabolites in rat urine by gas chromatography-mass spectrometry and liquid chromatography-mass spectrometry.
Journal of chromatography. B, Biomedical sciences and applications.
1997 Aug; 696(1):160-5. doi:
10.1016/s0378-4347(97)00231-4
. [PMID: 9300921] - E Y Choi, S G Kim, J W Lee, J K Yoo, J K Shin, N D Kim. Suppression of rat hepatic cytochrome P450 2E1 expression by isopropyl 2-(1,3-dithioetane-2-ylidene)-2-[N-(4-methyl-thiazol-2-yl)carbamoyl] acetate (YH439), an experimental hepatoprotectant: protective role against hepatic injury.
Biochemical pharmacology.
1996 Oct; 52(8):1219-25. doi:
10.1016/0006-2952(96)00474-1
. [PMID: 8937429] - W I Lee, W H Yoon, J H Park, J W Lee, C K Shim, M G Lee. Factors influencing the protein binding of YH-439 using an equilibrium dialysis technique. A new hepatoprotective agent.
Biopharmaceutics & drug disposition.
1995 Dec; 16(9):775-89. doi:
10.1002/bdd.2510160907
. [PMID: 8580401]