2,3-dinor-6-oxoprostaglandin F1alpha (BioDeep_00001876124)
代谢物信息卡片
2,3-dinor-6-oxoprostaglandin F1alpha
化学式: C18H30O6 (342.204228)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CCCCCC(C=CC1C(CC(C1CC(=O)CCC(=O)O)O)O)O
InChI: InChI=1S/C18H30O6/c1-2-3-4-5-12(19)6-8-14-15(17(22)11-16(14)21)10-13(20)7-9-18(23)24/h6,8,12,14-17,19,21-22H,2-5,7,9-11H2,1H3,(H,23,24)/b8-6+/t12-,14+,15+,16+,17-/m0/s1
描述信息
A prostanoid that is prostaglandin F1alpha lacking two methylenes in the carboxyalkyl chain and bearing an oxo group at the 6-position.
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代谢反应
0 个相关的代谢反应过程信息。
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在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
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文献列表
- Jane A Mitchell, Rebecca B Knowles, Nicholas S Kirkby, Daniel M Reed, Matthew L Edin, William E White, Melissa V Chan, Hilary Longhurst, Magdi M Yaqoob, Ginger L Milne, Darryl C Zeldin, Timothy D Warner. Kidney Transplantation in a Patient Lacking Cytosolic Phospholipase A2 Proves Renal Origins of Urinary PGI-M and TX-M.
Circulation research.
2018 02; 122(4):555-559. doi:
10.1161/circresaha.117.312144. [PMID: 29298774] - Haruyo Ujike-Omori, Yohei Maeshima, Masaru Kinomura, Katsuyuki Tanabe, Kiyoshi Mori, Hiroyuki Watatani, Norikazu Hinamoto, Hitoshi Sugiyama, Yoshiki Sakai, Hiroshi Morimatsu, Hirofumi Makino. The urinary levels of prostanoid metabolites predict acute kidney injury in heterogeneous adult Japanese ICU patients: a prospective observational study.
Clinical and experimental nephrology.
2015 Dec; 19(6):1024-36. doi:
10.1007/s10157-015-1092-4. [PMID: 25669623] - Jules I Schwartz, Bret J Musser, Wesley K Tanaka, William V Taggart, Anish Mehta, Keith M Gottesdiener, Howard E Greenberg. Inhibition of prostacyclin and thromboxane biosynthesis in healthy volunteers by single and multiple doses of acetaminophen and indomethacin.
Clinical pharmacology in drug development.
2015 09; 4(5):337-45. doi:
10.1002/cpdd.194. [PMID: 27137142] - Stephanie Ross, John Eikelboom, Sonia S Anand, Niclas Eriksson, Hertzel C Gerstein, Shamir Mehta, Stuart J Connolly, Lynda Rose, Paul M Ridker, Lars Wallentin, Daniel I Chasman, Salim Yusuf, Guillaume Paré. Association of cyclooxygenase-2 genetic variant with cardiovascular disease.
European heart journal.
2014 Sep; 35(33):2242-8a. doi:
10.1093/eurheartj/ehu168. [PMID: 24796340] - V Cavalca, B Rocca, I Squellerio, A Dragani, F Veglia, F Pagliaccia, B Porro, S S Barbieri, E Tremoli, C Patrono. In vivo prostacyclin biosynthesis and effects of different aspirin regimens in patients with essential thrombocythaemia.
Thrombosis and haemostasis.
2014 Jul; 112(1):118-27. doi:
10.1160/th13-10-0844. [PMID: 24671522] - C Skarke, N Alamuddin, J A Lawson, L Cen, K J Propert, G A Fitzgerald. Comparative impact on prostanoid biosynthesis of celecoxib and the novel nonsteroidal anti-inflammatory drug CG100649.
Clinical pharmacology and therapeutics.
2012 Jun; 91(6):986-93. doi:
10.1038/clpt.2012.3. [PMID: 22278334] - Wen-Liang Song, Jane Stubbe, Emanuela Ricciotti, Naji Alamuddin, Salam Ibrahim, Irene Crichton, Maxwell Prempeh, John A Lawson, Robert L Wilensky, Lars Melholt Rasmussen, Ellen Puré, Garret A FitzGerald. Niacin and biosynthesis of PGD₂by platelet COX-1 in mice and humans.
The Journal of clinical investigation.
2012 Apr; 122(4):1459-68. doi:
10.1172/jci59262. [PMID: 22406532] - Caoimhe M Lynch, Ruth O'Kelly, Bernard Stuart, Achim Treumann, Ronan Conroy, Carmen L Regan. The role of thromboxane A(2) in the pathogenesis of intrauterine growth restriction associated with maternal smoking in pregnancy.
Prostaglandins & other lipid mediators.
2011 Aug; 95(1-4):63-7. doi:
10.1016/j.prostaglandins.2011.06.007. [PMID: 21723954] - Matthew Blatnik, Rick C Steenwyk. Quantification of urinary PGEm, 6-keto PGF(1alpha) and 2,3-dinor-6-keto PGF(1alpha) by UFLC-MS/MS before and after exercise.
Prostaglandins & other lipid mediators.
2010 Sep; 93(1-2):8-13. doi:
10.1016/j.prostaglandins.2010.04.002. [PMID: 20416393] - Hiroyuki Fukushima, Kenjiro Kosaki, Reiko Sato, Tatsuhiko Yagihashi, Ryohei Gatayama, Kazuki Kodo, Takuya Hayashi, Maki Nakazawa, Takatoshi Tsuchihashi, Jun Maeda, Yoshifumi Kojima, Hiroyuki Yamagishi, Takao Takahashi. Mechanisms underlying early development of pulmonary vascular obstructive disease in Down syndrome: An imbalance in biosynthesis of thromboxane A2 and prostacyclin.
American journal of medical genetics. Part A.
2010 Aug; 152A(8):1919-24. doi:
10.1002/ajmg.a.33555. [PMID: 20583254] - L Zhao, T Ding, T Cyrus, Y Cheng, H Tian, M Ma, R Falotico, D Praticò. Low-dose oral sirolimus reduces atherogenesis, vascular inflammation and modulates plaque composition in mice lacking the LDL receptor.
British journal of pharmacology.
2009 Mar; 156(5):774-85. doi:
10.1111/j.1476-5381.2008.00080.x. [PMID: 19220291] - Caroline Signore, Sofía Aros, Jason D Morrow, James Troendle, Mary R Conley, Elizabeth Y Flanigan, Fernando Cassorla, James L Mills. Markers of oxidative stress and systemic vasoconstriction in pregnant women drinking > or =48 g of alcohol per day.
Alcoholism, clinical and experimental research.
2008 Nov; 32(11):1893-8. doi:
10.1111/j.1530-0277.2008.00773.x. [PMID: 18715278] - Jules I Schwartz, Chau Thach, Kenneth C Lasseter, Jutta Miller, David Hreniuk, Deborah A Hilliard, Karen M Snyder, Barry J Gertz, Keith M Gottesdiener. Effects of etoricoxib and comparator nonsteroidal anti-inflammatory drugs on urinary sodium excretion, blood pressure, and other renal function indicators in elderly subjects consuming a controlled sodium diet.
Journal of clinical pharmacology.
2007 Dec; 47(12):1521-31. doi:
10.1177/0091270007307878. [PMID: 17925592] - Josiane Arnaud, Muriel Bost, Dominique Vitoux, José Labarère, Pilar Galan, Henri Faure, Serge Hercberg, Jean-Claude Bordet, Anne-Marie Roussel, Philippe Chappuis. Effect of low dose antioxidant vitamin and trace element supplementation on the urinary concentrations of thromboxane and prostacyclin metabolites.
Journal of the American College of Nutrition.
2007 Oct; 26(5):405-11. doi:
10.1080/07315724.2007.10719629. [PMID: 17914127] - Marta L Capone, Stefania Tacconelli, Maria G Sciulli, Paola Anzellotti, Luigia Di Francesco, Gabriele Merciaro, Patrizia Di Gregorio, Paola Patrignani. Human pharmacology of naproxen sodium.
The Journal of pharmacology and experimental therapeutics.
2007 Aug; 322(2):453-60. doi:
10.1124/jpet.107.122283. [PMID: 17473175] - Dirk O Stichtenoth, Verena Marhauer, Dimitrios Tsikas, Frank-Mathias Gutzki, Jürgen C Frölich. Effects of specific COX-2-inhibition on renin release and renal and systemic prostanoid synthesis in healthy volunteers.
Kidney international.
2005 Nov; 68(5):2197-207. doi:
10.1111/j.1523-1755.2005.00676.x. [PMID: 16221219] - Pertti Saloheimo, Seppo Juvela, Asko Riutta, Juhani Pyhtinen, Matti Hillbom. Thromboxane and prostacyclin biosynthesis in patients with acute spontaneous intracerebral hemorrhage.
Thrombosis research.
2005; 115(5):367-73. doi:
10.1016/j.thromres.2004.08.026. [PMID: 15733969] - Merja Vainio, Asko Riutta, Anna-Maija Koivisto, Johanna Mäenpää. Prostacyclin, thromboxane A and the effect of low-dose ASA in pregnancies at high risk for hypertensive disorders.
Acta obstetricia et gynecologica Scandinavica.
2004 Dec; 83(12):1119-23. doi:
10.1111/j.0001-6349.2004.00396.x. [PMID: 15548142] - Koichi Hashimoto, Barney S Graham, Mark W Geraci, Garret A FitzGerald, Karine Egan, Weisong Zhou, Kasia Goleniewska, Jamye F O'Neal, Jason D Morrow, Russell K Durbin, Peter F Wright, Robert D Collins, Tatsuo Suzutani, R Stokes Peebles. Signaling through the prostaglandin I2 receptor IP protects against respiratory syncytial virus-induced illness.
Journal of virology.
2004 Oct; 78(19):10303-9. doi:
10.1128/jvi.78.19.10303-10309.2004. [PMID: 15367596] - Marta L Capone, Stefania Tacconelli, Maria G Sciulli, Marilena Grana, Emanuela Ricciotti, Pietro Minuz, Patrizia Di Gregorio, Gabriele Merciaro, Carlo Patrono, Paola Patrignani. Clinical pharmacology of platelet, monocyte, and vascular cyclooxygenase inhibition by naproxen and low-dose aspirin in healthy subjects.
Circulation.
2004 Mar; 109(12):1468-71. doi:
10.1161/01.cir.0000124715.27937.78. [PMID: 15037526] - D S Mastrogiannis, A Luckenbau, W F O'Brien. Cocaine decreases urinary prostacyclin release in pregnancy: correlation with uterine and umbilical Doppler velocimetry.
The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians.
2003 Dec; 14(6):383-8. doi:
10.1080/14767050412331312220. [PMID: 15061316] - George B Kudolo, Sheryl Dorsey, Janet Blodgett. Effect of the ingestion of Ginkgo biloba extract on platelet aggregation and urinary prostanoid excretion in healthy and Type 2 diabetic subjects.
Thrombosis research.
2002 Nov; 108(2-3):151-60. doi:
10.1016/s0049-3848(02)00394-8. [PMID: 12590952] - H Sinzinger. Comments on 'Relationship between thromboxane/prostacyclin ratio and diabetic vascular complications'.
Prostaglandins, leukotrienes, and essential fatty acids.
2002 Nov; 67(5):309-10. doi:
10.1054/plef.2002.0434. [PMID: 12445490] - Virpi Saareks, Pauli Ylitalo, István Mucha, Asko Riutta. Opposite effects of nicotinic acid and pyridoxine on systemic prostacyclin, thromboxane and leukotriene production in man.
Pharmacology & toxicology.
2002 Jun; 90(6):338-42. doi:
10.1034/j.1600-0773.2002.900608.x. [PMID: 12403056] - D O Stichtenoth, F J Kreutzer, F M Gutzki, D Tsikas, V Nowak, J C Frölich. Effects of intravenous oxygen on prostacyclin and thromboxane formation in patients with peripheral occlusive arterial disease.
Prostaglandins, leukotrienes, and essential fatty acids.
2001 Oct; 65(4):211-4. doi:
10.1054/plef.2001.0313. [PMID: 11728174] - T Hishinuma, H Tsukamoto, K Suzuki, M Mizugaki. Relationship between thromboxane/prostacyclin ratio and diabetic vascular complications.
Prostaglandins, leukotrienes, and essential fatty acids.
2001 Oct; 65(4):191-6. doi:
10.1054/plef.2001.0310. [PMID: 11728171] - R Kaaja, V Pettilä, P Leinonen, O Ylikorkala. Increased thromboxane production in women with a history of venous thromboembolic event: effect of heparins.
British journal of haematology.
2001 Sep; 114(3):655-9. doi:
10.1046/j.1365-2141.2001.03001.x. [PMID: 11552994] - N P Dowd, M Scully, S R Adderley, A J Cunningham, D J Fitzgerald. Inhibition of cyclooxygenase-2 aggravates doxorubicin-mediated cardiac injury in vivo.
The Journal of clinical investigation.
2001 Aug; 108(4):585-90. doi:
10.1172/jci11334. [PMID: 11518732] - D Praticò, C Tillmann, Z B Zhang, H Li, G A FitzGerald. Acceleration of atherogenesis by COX-1-dependent prostanoid formation in low density lipoprotein receptor knockout mice.
Proceedings of the National Academy of Sciences of the United States of America.
2001 Mar; 98(6):3358-63. doi:
10.1073/pnas.061607398. [PMID: 11248083] - N J Brown, J V Gainer, L J Murphey, D E Vaughan. Bradykinin stimulates tissue plasminogen activator release from human forearm vasculature through B(2) receptor-dependent, NO synthase-independent, and cyclooxygenase-independent pathway.
Circulation.
2000 Oct; 102(18):2190-6. doi:
10.1161/01.cir.102.18.2190. [PMID: 11056091] - F M Delemarre, C M Thomas, R J van den Berg, H W Jongsma, E A Steegers. Urinary prostaglandin excretion in pregnancy: the effect of dietary sodium restriction.
Prostaglandins, leukotrienes, and essential fatty acids.
2000 Oct; 63(4):209-15. doi:
10.1054/plef.2000.0211. [PMID: 11049696] - O Belton, D Byrne, D Kearney, A Leahy, D J Fitzgerald. Cyclooxygenase-1 and -2-dependent prostacyclin formation in patients with atherosclerosis.
Circulation.
2000 Aug; 102(8):840-5. doi:
10.1161/01.cir.102.8.840. [PMID: 10952950] - D Tsikas, F M Gutzki, M Böhme, I Fuchs, J C Frölich. Solid- and liquid-phase extraction for the gas chromatographic-tandem mass spectrometric quantification of 2,3-dinor-thromboxane B2 and 2,3-dinor-6-oxo-prostaglandin F1 alpha in human urine.
Journal of chromatography. A.
2000 Jul; 885(1-2):351-9. doi:
10.1016/s0021-9673(99)00967-x. [PMID: 10941682] - H Numminen, M Syrjälä, G Benthin, M Kaste, M Hillbom. The effect of acute ingestion of a large dose of alcohol on the hemostatic system and its circadian variation.
Stroke.
2000 Jun; 31(6):1269-73. doi:
10.1161/01.str.31.6.1269. [PMID: 10835443] - H Tanaka, T Igarashi, T Saitoh, S Teramoto, N Miyazaki, S Kaneko, M Ohmichi, S Abe. Can urinary eicosanoids be a potential predictive marker of clinical response to thromboxane A2 receptor antagonist in asthmatic patients?.
Respiratory medicine.
1999 Dec; 93(12):891-7. doi:
10.1016/s0954-6111(99)90055-0. [PMID: 10653051] - M Mizugaki, T Hishinuma, E Matsumura, Y Murai, T Yamazaki, S Yamanobe, M Tamai. Monitoring of the thromboxane A2/prostacyclin ratio in the urine of patients with retinal vascular occlusion through the low-dose-aspirin therapy using the gas chromatography/selected ion monitoring method.
Prostaglandins & other lipid mediators.
1999 Nov; 58(5-6):253-62. doi:
10.1016/s0090-6980(99)00030-1. [PMID: 10593167] - T Hishinuma, Y Koseki, Y Murai, T Yamazaki, K Suzuki, M Mizugaki. Urinary thromboxane A2/prostacyclin balance reflects the pathological state of a diabetic.
Prostaglandins & other lipid mediators.
1999 Nov; 58(5-6):263-71. doi:
10.1016/s0090-6980(99)00029-5. [PMID: 10593168] - B Hoch, M Bernhard. Reduced prostacyclin to thromboxane A2 ratio is correlated with central apneas in preterm infants.
Prostaglandins & other lipid mediators.
1999 Nov; 58(5-6):285-90. doi:
10.1016/s0090-6980(99)00043-x. [PMID: 10593170] - P Arvola, X Wu, M Kähönen, H Mäkynen, A Riutta, I Mucha, T Solakivi, H Kainulainen, I Pörsti. Exercise enhances vasorelaxation in experimental obesity associated hypertension.
Cardiovascular research.
1999 Sep; 43(4):992-1002. doi:
10.1016/s0008-6363(99)00141-8. [PMID: 10615427] - A E Barden, L J Beilin, J Ritchie, B N Walters, C Michael. Does a predisposition to the metabolic syndrome sensitize women to develop pre-eclampsia?.
Journal of hypertension.
1999 Sep; 17(9):1307-15. doi:
10.1097/00004872-199917090-00011. [PMID: 10489109] - J L Mills, R DerSimonian, E Raymond, J D Morrow, L J Roberts, J D Clemens, J C Hauth, P Catalano, B Sibai, L B Curet, R J Levine. Prostacyclin and thromboxane changes predating clinical onset of preeclampsia: a multicenter prospective study.
JAMA.
1999 Jul; 282(4):356-62. doi:
10.1001/jama.282.4.356. [PMID: 10432033] - J D Morrow, J A Oates, L J Roberts, W E Zackert, T A Mitchell, G Lazarus, C Guzzo. Increased formation of thromboxane in vivo in humans with mastocytosis.
The Journal of investigative dermatology.
1999 Jul; 113(1):93-7. doi:
10.1046/j.1523-1747.1999.00624.x. [PMID: 10417625] - F Catella-Lawson, B McAdam, B W Morrison, S Kapoor, D Kujubu, L Antes, K C Lasseter, H Quan, B J Gertz, G A FitzGerald. Effects of specific inhibition of cyclooxygenase-2 on sodium balance, hemodynamics, and vasoactive eicosanoids.
The Journal of pharmacology and experimental therapeutics.
1999 May; 289(2):735-41. doi:
NULL. [PMID: 10215647] - B F McAdam, F Catella-Lawson, I A Mardini, S Kapoor, J A Lawson, G A FitzGerald. Systemic biosynthesis of prostacyclin by cyclooxygenase (COX)-2: the human pharmacology of a selective inhibitor of COX-2.
Proceedings of the National Academy of Sciences of the United States of America.
1999 Jan; 96(1):272-7. doi:
10.1073/pnas.96.1.272. [PMID: 9874808] - T Lindström, E Gullichsen, A Riutta. The effect of unreamed and reamed intramedullary nailing on the urinary excretion of prostacyclin and thromboxane A2 metabolites in patients with tibial shaft fractures.
The Journal of trauma.
1998 Oct; 45(4):743-6. doi:
10.1097/00005373-199810000-00020. [PMID: 9783614] - C L Regan, B F McAdam, P McParland, P C Boylan, G A FitzGerald, D J Fitzgerald. Reduced fetal exposure to aspirin using a novel controlled-release preparation in normotensive and hypertensive pregnancies.
British journal of obstetrics and gynaecology.
1998 Jul; 105(7):732-8. doi:
10.1111/j.1471-0528.1998.tb10203.x. [PMID: 9692413] - J M Moutquin, C Lindsay, N Arial, P De Grandpré, R C-Gaudreault, J C Forest, J Massé. Do prostacyclin and thromboxane contribute to the 'protective effect' of pregnancies with chronic hypertension? A preliminary prospective longitudinal study.
American journal of obstetrics and gynecology.
1997 Dec; 177(6):1483-90. doi:
10.1016/s0002-9378(97)70095-4. [PMID: 9423755] - C Lahoz, R Alonso, J M Ordovás, A López-Farré, M de Oya, P Mata. Effects of dietary fat saturation on eicosanoid production, platelet aggregation and blood pressure.
European journal of clinical investigation.
1997 Sep; 27(9):780-7. doi:
10.1046/j.1365-2362.1997.1860735.x. [PMID: 9352251] - K Farker, H Schweer, R Vollandt, N Nassr, U Nagel, H W Seyberth, A Hoffmann, M Oettel. Measurements of urinary prostaglandins in young ovulatory women during the menstrual cycle and in postmenopausal women.
Prostaglandins.
1997 Sep; 54(3):655-64. doi:
10.1016/s0090-6980(97)00131-7. [PMID: 9373880] - M Rautanen, E Gullichsen, A Riutta, K Kuttila, I Mucha, O Nelimarkka, J Niinikoski. Experimental fat embolism induces urine 2,3-dinor-6-ketoprostaglandin F1alpha and 11-dehydrothromboxane B2 excretion in pigs.
Critical care medicine.
1997 Jul; 25(7):1215-21. doi:
10.1097/00003246-199707000-00025. [PMID: 9233750] - J Wübert, E Reder, A Kaser, P C Weber, R L Lorenz. Simultaneous solid phase extraction, derivatization, and gas chromatographic mass spectrometric quantification of thromboxane and prostacyclin metabolites, prostaglandins, and isoprostanes in urine.
Analytical chemistry.
1997 Jun; 69(11):2143-6. doi:
10.1021/ac9611430. [PMID: 9183177] - D Henrion, E Dechaux, F J Dowell, J Maclour, J L Samuel, B I Lévy, J B Michel. Alteration of flow-induced dilatation in mesenteric resistance arteries of L-NAME treated rats and its partial association with induction of cyclo-oxygenase-2.
British journal of pharmacology.
1997 May; 121(1):83-90. doi:
10.1038/sj.bjp.0701109. [PMID: 9146891] - P Rossi, P Kuukasjärvi, J P Salenius, M Tarkka, T Kerttula, J Alanko, I Mucha, A Riutta. Percutaneous transluminal angioplasty increases thromboxane A2 production in claudicants.
Prostaglandins, leukotrienes, and essential fatty acids.
1997 May; 56(5):369-72. doi:
10.1016/s0952-3278(97)90585-8. [PMID: 9175173] - A Ferretti, G J Nelson, P C Schmidt, D S Kelley, G Bartolini, V P Flanagan. Increased dietary arachidonic acid enhances the synthesis of vasoactive eicosanoids in humans.
Lipids.
1997 Apr; 32(4):435-9. doi:
10.1007/s11745-997-0057-5. [PMID: 9113633] - P Rossi, P Kuukasjärvi, A Riutta, J P Salenius, M Tarkka, I Mucha, T Kerttula, J Alanko. Prostacyclin and thromboxane A2 synthesis are increased in acute lower limb ischaemia.
Prostaglandins, leukotrienes, and essential fatty acids.
1996 Dec; 55(6):433-6. doi:
10.1016/s0952-3278(96)90127-1. [PMID: 9014222] - N J Brown, D Ryder, J V Gainer, J D Morrow, J Nadeau. Differential effects of angiotensin converting enzyme inhibitors on the vasodepressor and prostacyclin responses to bradykinin.
The Journal of pharmacology and experimental therapeutics.
1996 Nov; 279(2):703-12. doi:
NULL. [PMID: 8930174] - P O Kimblad, K Gréen, T Sjöberg, S Steen. Prostanoid release after lung transplantation.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation.
1996 Oct; 15(10):999-1004. doi:
NULL. [PMID: 8913917] - W R Schaefer, R J Seufert, F W Casper, H P Zahradnik. Urinary excretion of 2,3-dinor-6-keto-PGF1 alpha and 11-dehydro-TXB2 by the gravid spontaneously hypertensive rat.
Prostaglandins.
1996 Jul; 52(1):1-11. doi:
10.1016/0090-6980(96)00049-4. [PMID: 8875634] - T Hishinuma, G S Yu, M Takabatake, Y Nakagawa, K Ito, M Nishikawa, M Ishibashi, K Suzuki, M Matsumoto, T Toyoda, M Mizugaki. Analysis of the thromboxane/prostacyclin balance in human urine by gas chromatography/selected ion monitoring: abnormalities in diabetics.
Prostaglandins, leukotrienes, and essential fatty acids.
1996 Jun; 54(6):445-9. doi:
10.1016/s0952-3278(96)90029-0. [PMID: 8888357] - A Ferretti, V P Flanagan. Antithromboxane activity of dietary alpha-linolenic acid: a pilot study.
Prostaglandins, leukotrienes, and essential fatty acids.
1996 Jun; 54(6):451-5. doi:
10.1016/s0952-3278(96)90030-7. [PMID: 8888358] - R M van der Weiden, F M Helmerhorst, M J Keirse. Prostanoid excretion in incipient singleton and twin pregnancies.
American journal of obstetrics and gynecology.
1996 May; 174(5):1614-7. doi:
10.1016/s0002-9378(96)70616-6. [PMID: 9065139] - P Pancera, E Arosio, P Minuz, F Pirante, M Ribul, A Lechi. Changes in peripheral hemodynamics and vasodilating prostaglandins after high-dose short-term ibuprofen in chronically treated hypertensive patients.
Prostaglandins, leukotrienes, and essential fatty acids.
1996 Mar; 54(3):217-22. doi:
10.1016/s0952-3278(96)90020-4. [PMID: 8860111] - J M Ritter, S E Brett, J D Woods, N Benjamin, P D Stratton, S E Barrow. Prostacyclin biosynthesis in essential hypertension before and during treatment.
Journal of human hypertension.
1996 Jan; 10(1):37-42. doi:
NULL. [PMID: 8642189] - R M van der Weiden, F M Helmerhorst, M J Keirse. Prostanoid excretion before in vitro fertilization relates to the likelihood of pregnancy.
Prostaglandins, leukotrienes, and essential fatty acids.
1995 Dec; 53(6):419-21. doi:
10.1016/0952-3278(95)90106-x. [PMID: 8821123] - D O Stichtenoth, N Selve, D Tsikas, F M Gutzki, J C Frölich. Increased total body synthesis of prostacyclin in rats with adjuvant arthritis.
Prostaglandins.
1995 Nov; 50(5-6):331-40. doi:
10.1016/0090-6980(95)00137-9. [PMID: 8838242] - I Rauramo, S Ilmonen, L Viinikka, O Ylikorkala. Prostacyclin and thromboxane in pregnant and nonpregnant women in response to exercise.
Obstetrics and gynecology.
1995 Jun; 85(6):1027-30. doi:
10.1016/0029-7844(95)00048-v. [PMID: 7770249] - R H Böger, S M Bode-Böger, E P Schröder, D Tsikas, J C Frölich. Increased prostacyclin production during exercise in untrained and trained men: effect of low-dose aspirin.
Journal of applied physiology (Bethesda, Md. : 1985).
1995 May; 78(5):1832-8. doi:
10.1152/jappl.1995.78.5.1832. [PMID: 7649919] - G Rasmanis, O Vesterqvist, K Gréen, P Henriksson. Implications of the prognostic importance of exercise-induced thromboxane formation in survivors of an acute myocardial infarction.
Prostaglandins.
1995 Apr; 49(4):247-53. doi:
10.1016/0090-6980(95)00019-7. [PMID: 7667506] - M Mizugaki, T Hishinuma, G S Yu, K Ito, M Nishikawa, Y Ohyama, M Ishibashi, Y Nakagawa, N Harima. Microdetermination of 2,3-dinor-6-ketoprostaglandin F1 alpha in human urine using gas chromatography-high-resolution selected-ion monitoring.
Journal of chromatography. B, Biomedical applications.
1994 Aug; 658(1):11-9. doi:
10.1016/0378-4347(94)00174-x. [PMID: 7952110] - A Riutta, E Nurmi, C Weber, G Hansson, H Vapaatalo, I Mucha. Selective solid-phase extraction of urinary 2,3-dinor-6-ketoprostaglandin F1 alpha for determination with radioimmunoassay.
Analytical biochemistry.
1994 Aug; 220(2):351-9. doi:
10.1006/abio.1994.1349. [PMID: 7978278] - A Riutta, T Kerttula, E Sievi, J Alanko. Adrenaline infusion increases systemic prostacyclin production in man.
Prostaglandins.
1994 Jul; 48(1):43-51. doi:
10.1016/0090-6980(94)90095-7. [PMID: 7972879] - V C Daniel, T A Minton, N J Brown, J H Nadeau, J D Morrow. Simplified assay for the quantification of 2,3-dinor-6-keto-prostaglandin F1 alpha by gas chromatography-mass spectrometry.
Journal of chromatography. B, Biomedical applications.
1994 Mar; 653(2):117-22. doi:
10.1016/0378-4347(93)e0432-p. [PMID: 8205238] - A Barden, L J Beilin, J Ritchie, B N Walters, C A Michael. Plasma and urinary endothelin 1, prostacyclin metabolites and platelet consumption in pre-eclampsia and essential hypertensive pregnancy.
Blood pressure.
1994 Mar; 3(1-2):38-46. doi:
10.3109/08037059409101520. [PMID: 8199718] - H Schweer, B Watzer, H W Seyberth. Determination of seven prostanoids in 1 ml of urine by gas chromatography-negative ion chemical ionization triple stage quadrupole mass spectrometry.
Journal of chromatography.
1994 Feb; 652(2):221-7. doi:
10.1016/0378-4347(93)e0408-i. [PMID: 8006107] - M Hiramatsu, Y Hayashi, S Yamamoto, A Hayashi, M Sawada, N Hamanaka, K Yamashita. Application of an alpha-sidechain length-specific monoclonal antibody to immunoaffinity purification and enzyme immunoassay of 2,3-dinor-6-keto-prostaglandin F1 alpha from human urine.
Prostaglandins, leukotrienes, and essential fatty acids.
1994 Feb; 50(2):69-79. doi:
10.1016/0952-3278(94)90150-3. [PMID: 8171070] - A Ferretti, V P Flanagan. Assay of urinary 2,3-dinor-6-oxo prostaglandin F1 alpha by gas chromatography-tandem mass spectrometry.
Journal of chromatography.
1993 Dec; 622(2):109-15. doi:
10.1016/0378-4347(93)80256-4. [PMID: 8150859] - I Adatia, S E Barrow, P D Stratton, V M Miall-Allen, J M Ritter, S G Haworth. Thromboxane A2 and prostacyclin biosynthesis in children and adolescents with pulmonary vascular disease.
Circulation.
1993 Nov; 88(5 Pt 1):2117-22. doi:
10.1161/01.cir.88.5.2117. [PMID: 8222105] - N L Benowitz, G A Fitzgerald, M Wilson, Q Zhang. Nicotine effects on eicosanoid formation and hemostatic function: comparison of transdermal nicotine and cigarette smoking.
Journal of the American College of Cardiology.
1993 Oct; 22(4):1159-67. doi:
10.1016/0735-1097(93)90431-y. [PMID: 7691912] - J C Bordet, M de Lorgeril, S Durbin, P Boissonnat, S Renaud, G Dureau, M Dechavanne. Systemic but not renal production of prostacyclin is highly reduced in cyclosporin-treated heart transplant recipients.
The American journal of cardiology.
1993 Aug; 72(5):486-7. doi:
10.1016/0002-9149(93)91152-8. [PMID: 8352201] - A Wennmalm, G Benthin, E F Granström, L Persson, S Winell. Maintained hyperexcretion of thromboxane A2 metabolite in healthy young cigarette smokers: results from a prospective study in randomly sampled males with stable smoking habits.
Clinical physiology (Oxford, England).
1993 May; 13(3):257-64. doi:
10.1111/j.1475-097x.1993.tb00325.x. [PMID: 8519161] - W F O'Brien, J Krammer, T D O'Leary, D S Mastrogiannis. The effect of acetaminophen on prostacyclin production in pregnant women.
American journal of obstetrics and gynecology.
1993 Apr; 168(4):1164-9. doi:
10.1016/0002-9378(93)90362-m. [PMID: 8475962] - I Foulon, D Bachir, F Galacteros, J Maclouf. Increased in vivo production of thromboxane in patients with sickle cell disease is accompanied by an impairment of platelet functions to the thromboxane A2 agonist U46619.
Arteriosclerosis and thrombosis : a journal of vascular biology.
1993 Mar; 13(3):421-6. doi:
10.1161/01.atv.13.3.421. [PMID: 8443146] - H Morio, A Hirai, T Terano, Y Tamura, S Yoshida. Effect of the infusion of OKY-046, a thromboxane A2 synthase inhibitor, on urinary metabolites of prostacyclin and thromboxane A2 in healthy human subjects.
Thrombosis and haemostasis.
1993 Mar; 69(3):276-81. doi:
10.1055/s-0038-1651595. [PMID: 8470052] - I Adatia, S E Barrow, P Stratton, J M Ritter, S G Haworth. Abnormalities in the biosynthesis of thromboxane A2 and prostacyclin in children with cyanotic congenital heart disease.
British heart journal.
1993 Feb; 69(2):179-82. doi:
10.1136/hrt.69.2.179. [PMID: 8435245] - H I Chen, C J Jen, W C Chang. Effects of exercise training on the biosynthesis of prostacyclin and thromboxane in rats.
Acta physiologica Scandinavica.
1993 Jan; 147(1):109-15. doi:
10.1111/j.1748-1716.1993.tb09478.x. [PMID: 8452036] - D Closa, J Rosello-Catafau, A Martrat, G Hotter, O Bulbena, L Fernandez-Cruz, E Gelpi. Changes of systemic prostacyclin and thromboxane A2 in sodium taurocholate- and cerulein-induced acute pancreatitis in rats.
Digestive diseases and sciences.
1993 Jan; 38(1):33-8. doi:
10.1007/bf01296770. [PMID: 7678383] - A Jendryczko, J Tomala. An imbalance between the excretion of thromboxane and prostacyclin metabolites in women after the menopause.
Zentralblatt fur Gynakologie.
1993; 115(4):163-6. doi:
NULL. [PMID: 8503234] - C Rångemark, G Benthin, E F Granström, L Persson, S Winell, A Wennmalm. Tobacco use and urinary excretion of thromboxane A2 and prostacyclin metabolites in women stratified by age.
Circulation.
1992 Nov; 86(5):1495-500. doi:
10.1161/01.cir.86.5.1495. [PMID: 1423963] - H Tohgi, S Konno, K Tamura, B Kimura, K Kawano. Effects of low-to-high doses of aspirin on platelet aggregability and metabolites of thromboxane A2 and prostacyclin.
Stroke.
1992 Oct; 23(10):1400-3. doi:
10.1161/01.str.23.10.1400. [PMID: 1412574] - A Wennmalm, G Benthin, E F Granström, L Persson, S Winell. 2,3-Dinor metabolites of thromboxane A2 and prostacyclin in urine from healthy human subjects: diurnal variation and relation to 24h excretion.
Clinical science (London, England : 1979).
1992 Oct; 83(4):461-5. doi:
10.1042/cs0830461. [PMID: 1330409] - J S Lin, S M Lui, C M Chen, W C Chang. The change of urinary 11-dehydro-thromboxane B2 and 2,3-dinor-6-keto-prostaglandin F1 alpha in arteriogenic impotence.
The Journal of urology.
1992 Aug; 148(2 Pt 1):311-3. doi:
10.1016/s0022-5347(17)36581-3. [PMID: 1635125] - A Martrat, J Roselló-Catafau, D Closa, G Hotter, D Vargas, L Fernández-Cruz, E Gelpí. Altered systemic and tissue prostacyclin in cerulein induced acute pancreatitis in rats.
Prostaglandins, leukotrienes, and essential fatty acids.
1992 Aug; 46(4):261-4. doi:
10.1016/0952-3278(92)90032-e. [PMID: 1384068] - B W Christman, C D McPherson, J H Newman, G A King, G R Bernard, B M Groves, J E Loyd. An imbalance between the excretion of thromboxane and prostacyclin metabolites in pulmonary hypertension.
The New England journal of medicine.
1992 Jul; 327(2):70-5. doi:
10.1056/nejm199207093270202. [PMID: 1603138] - P T Larsson, G Olsson, B Angelin, E Granström, G Hansson, P Hjemdahl. Metoprolol does not reduce platelet aggregability during sympatho-adrenal stimulation.
European journal of clinical pharmacology.
1992; 42(4):413-21. doi:
10.1007/bf00280128. [PMID: 1387607] - A Wennmalm. Formation of prostacyclin during administration of beta 1-selective and non-selective beta-adrenergic antagonists in healthy humans.
Clinical physiology (Oxford, England).
1992 Jan; 12(1):107-15. doi:
10.1111/j.1475-097x.1992.tb00297.x. [PMID: 1347260] - F Greco, F Tamburrelli, G Ciabattoni. Intra-articular osteoid osteoma.
Italian journal of orthopaedics and traumatology.
1992; 18(1):63-9. doi:
NULL. [PMID: 1399536] - C Guarner, G Soriano, J Such, M Teixidó, I Ramis, O Bulbena, J Roselló, F Guarner, E Gelpi, J Balanzó. Systemic prostacyclin in cirrhotic patients. Relationship with portal hypertension and changes after intestinal decontamination.
Gastroenterology.
1992 Jan; 102(1):303-9. doi:
10.1016/0016-5085(92)91814-k. [PMID: 1727763] - T Kurki, L Viinikka, O Ylikorkala. Urinary excretion of prostacyclin and thromboxane metabolites in threatened preterm labor: effect of indomethacin and nylidrin.
American journal of obstetrics and gynecology.
1992 Jan; 166(1 Pt 1):150-4. doi:
10.1016/0002-9378(92)91851-z. [PMID: 1733190] - R Hui, M Robillard, J H Grose, M Lebel, P Falardeau. Arachidonic acid does not share the antihypertensive properties of linoleic acid and fish oil omega-3 fatty acids in a model of angiotensin II-induced hypertension in the rat.
Clinical and investigative medicine. Medecine clinique et experimentale.
1991 Dec; 14(6):518-24. doi:
NULL. [PMID: 1794205]