Indolylacryloylglycine (BioDeep_00001876054)
代谢物信息卡片
Indolylacryloylglycine
化学式: C13H12N2O3 (244.0848)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1=CC=C2C(=C1)C(=CN2)C=CC(=O)NCC(=O)O
InChI: InChI=1S/C13H12N2O3/c16-12(15-8-13(17)18)6-5-9-7-14-11-4-2-1-3-10(9)11/h1-7,14H,8H2,(H,15,16)(H,17,18)/b6-5+
相关代谢途径
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代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
| 亚细胞结构定位 | 关联基因列表 |
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文献列表
- Andrea E Steuer, Dominique Kamber, Thomas Kraemer. Evaluation of endogenous urinary biomarkers for indirect detection of urine adulteration attempts by five different chemical adulterants in mass spectrometry methods.
Drug testing and analysis.
2019 May; 11(5):638-648. doi:
10.1002/dta.2539. [PMID: 30408836] - Julie Wilson, Barry Wright, Sandra Jost, Robert Smith, Helen Pearce, Sally Richardson. Can urinary indolylacroylglycine levels be used to determine whether children with autism will benefit from dietary intervention?.
Pediatric research.
2017 Apr; 81(4):672-679. doi:
10.1038/pr.2016.256. [PMID: 27879968] - Neil R Dalton, Susie Chandler, Charles Turner, Tony Charman, Andrew Pickles, Emily Simonoff, Gillian Baird. Measurement of urine indolylacroylglycine is not useful in the diagnosis or dietary management of autism.
Autism research : official journal of the International Society for Autism Research.
2017 Mar; 10(3):408-413. doi:
10.1002/aur.1688. [PMID: 27569540] - Josep Marcos, Maria Ibañez, Rosa Ventura, Jordi Segura, Jordi To-Figueras, Oscar J Pozo. Mass spectrometric characterisation of a condensation product between porphobilinogen and indolyl-3-acryloylglycine in urine of patients with acute intermittent porphyria.
Journal of mass spectrometry : JMS.
2015 Jul; 50(7):929-37. doi:
10.1002/jms.3603. [PMID: 26349648] - Lennart Pedersen, Sarah Parlar, Kajsa Kvist, Paul Whiteley, Paul Shattock. Data mining the ScanBrit study of a gluten- and casein-free dietary intervention for children with autism spectrum disorders: behavioural and psychometric measures of dietary response.
Nutritional neuroscience.
2014 Sep; 17(5):207-13. doi:
10.1179/1476830513y.0000000082. [PMID: 24075141] - T Andrew Clayton. Metabolic differences underlying two distinct rat urinary phenotypes, a suggested role for gut microbial metabolism of phenylalanine and a possible connection to autism.
FEBS letters.
2012 Apr; 586(7):956-61. doi:
10.1016/j.febslet.2012.01.049. [PMID: 22306194] - Lv Wang, Manya T Angley, Jacobus P Gerber, Michael J Sorich. A review of candidate urinary biomarkers for autism spectrum disorder.
Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals.
2011 Nov; 16(7):537-52. doi:
10.3109/1354750x.2011.598564. [PMID: 22022826] - Paul Whiteley, Demetrious Haracopos, Ann-Mari Knivsberg, Karl Ludvig Reichelt, Sarah Parlar, Judith Jacobsen, Anders Seim, Lennart Pedersen, Maja Schondel, Paul Shattock. The ScanBrit randomised, controlled, single-blind study of a gluten- and casein-free dietary intervention for children with autism spectrum disorders.
Nutritional neuroscience.
2010 Apr; 13(2):87-100. doi:
10.1179/147683010x12611460763922. [PMID: 20406576] - Lv Wang, Manya T Angley, Jacobus P Gerber, Robyn L Young, Damien V Abarno, Ross A McKinnon, Michael J Sorich. Is urinary indolyl-3-acryloylglycine a biomarker for autism with gastrointestinal symptoms?.
Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals.
2009 Dec; 14(8):596-603. doi:
10.3109/13547500903183962. [PMID: 19697973] - Kevin Carr, Paul Whiteley, Paul Shattock. Development and reproducibility of a novel high-performance liquid-chromatography monolithic column method for the detection and quantification of trans-indolyl-3-acryloylglycine in human urine.
Biomedical chromatography : BMC.
2009 Oct; 23(10):1108-15. doi:
10.1002/bmc.1231. [PMID: 19402183] - Barry Wright, Andrzej Marek Brzozowski, Elizabeth Calvert, Helen Farnworth, David M Goodall, Ian Holbrook, Gregg Imrie, Jo Jordan, Anne Kelly, Jeremy Miles, Rob Smith, Joel Town. Is the presence of urinary indolyl-3-acryloylglycine associated with autism spectrum disorder?.
Developmental medicine and child neurology.
2005 Mar; 47(3):190-2. doi:
10.1017/s0012162205000344. [PMID: 15739724] - Gillian Bull, Paul Shattock, Paul Whiteley, Roz Anderson, Paul W Groundwater, John W Lough, George Lees. Indolyl-3-acryloylglycine (IAG) is a putative diagnostic urinary marker for autism spectrum disorders.
Medical science monitor : international medical journal of experimental and clinical research.
2003 Oct; 9(10):CR422-5. doi:
NULL. [PMID: 14523330] - K M Solaas, O Skjeldal, M L G Gardner, F B Kase, K L Reichelt. Urinary peptides in Rett syndrome.
Autism : the international journal of research and practice.
2002 Sep; 6(3):315-28. doi:
10.1177/1362361302006003008. [PMID: 12212921] - Rosaleen J Anderson, David J Bendell, Ian Garnett, Paul W Groundwater, W John Lough, Malcolm J Mills, Dawn Savery, Paul E G Shattock. Identification of indolyl-3-acryloylglycine in the urine of people with autism.
The Journal of pharmacy and pharmacology.
2002 Feb; 54(2):295-8. doi:
10.1211/0022357021778349. [PMID: 11858215] - E Marklová. Where does indolylacrylic acid come from?.
Amino acids.
1999; 17(4):401-13. doi:
10.1007/bf01361665. [PMID: 10707769] - M J Mills, D Savery, P E Shattock. Rapid analysis of low levels of indolyl-3-acryloylglycine in human urine by high-performance liquid chromatography.
Journal of chromatography. B, Biomedical sciences and applications.
1998 Aug; 712(1-2):51-8. doi:
10.1016/s0378-4347(98)00153-4. [PMID: 9698228] - E Marklová, A Fojtásková. High-performance liquid chromatographic profiling of indolylacryloylglycine and its possible precursors in body fluids.
Journal of chromatography. A.
1996 Apr; 730(1-2):133-7. doi:
10.1016/0021-9673(95)00943-4. [PMID: 8680585] - E Marklová, L Klein, I M Hais. Urinary excretion of indolylacryloylglycine, indolylacetic acid and 5-hydroxyindolylacetic acid in burn patients.
Sbornik vedeckych praci Lekarske fakulty Karlovy university v Hradci Kralove.
1993; 36(4-5):299-303. doi:
NULL. [PMID: 8599072] - E Marklová, L Sobotka, I M Hais. [Metabolism of indoleacrylic acid. II. The effect of diet on the excretion of indoleacryloylglycine in urine].
Sbornik vedeckych praci Lekarske fakulty Karlovy univerzity v Hradci Kralove. Supplementum.
1986; 29(4-5):443-9. doi:
NULL. [PMID: 3125600] - E Marklová, L Malina, I M Hais. Urinary excretion of indolyl-3-acryloylglycine in some skin affections.
Clinica chimica acta; international journal of clinical chemistry.
1975 Nov; 64(3):273-80. doi:
10.1016/0009-8981(75)90354-x. [PMID: 1183041] - E Marklová, I M Hais. A method for the estimation of indolylacryloylglycine in urine.
Clinica chimica acta; international journal of clinical chemistry.
1972 Sep; 40(2):455-60. doi:
10.1016/0009-8981(72)90358-0. [PMID: 5056145]
