N-Tert-Butyl-3-(4-(2-methoxyphenyl)-piperazin-1-yl)-2-phenylpropanamide (BioDeep_00001876053)
代谢物信息卡片
化学式: C24H33N3O2 (395.25726380000003)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC(C)(C)NC(=O)C(CN1CCN(CC1)C2=CC=CC=C2OC)C3=CC=CC=C3
InChI: InChI=1S/C24H33N3O2/c1-24(2,3)25-23(28)20(19-10-6-5-7-11-19)18-26-14-16-27(17-15-26)21-12-8-9-13-22(21)29-4/h5-13,20H,14-18H2,1-4H3,(H,25,28)
描述信息
D018377 - Neurotransmitter Agents > D018490 - Serotonin Agents > D012702 - Serotonin Antagonists
同义名列表
相关代谢途径
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代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
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0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Cláudia R Zamberlam, Myrcea A S Tilger, Laís Moraes, Janete M Cerutti, Suzete M Cerutti. Ginkgo biloba treatments reverse the impairment of conditioned suppression acquisition induced by GluN2B-NMDA and 5-HT1A receptor blockade: Modulatory effects of the circuitry of the dorsal hippocampal formation.
Physiology & behavior.
2019 10; 209(?):112534. doi:
10.1016/j.physbeh.2019.04.023. [PMID: 31071338] - Simona Bertoni, Valentina Arcaro, Valentina Vivo, Alberto Rapalli, Massimiliano Tognolini, Anna Maria Cantoni, Francesca Saccani, Lisa Flammini, Giuseppe Domenichini, Vigilio Ballabeni, Elisabetta Barocelli. Suppression of inflammatory events associated to intestinal ischemia-reperfusion by 5-HT1A blockade in mice.
Pharmacological research.
2014 Mar; 81(?):17-25. doi:
10.1016/j.phrs.2014.02.002. [PMID: 24548822] - Y Tohyama, F Yamane, M F Merid, M Diksic. Effects of selective 5-HT1A receptor antagonists on regional serotonin synthesis in the rat brain: an autoradiographic study with alpha-[14C]methyl-L-tryptophan.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology.
2001 Jun; 11(3):193-202. doi:
10.1016/s0924-977x(01)00076-1. [PMID: 11418278] - A Siddiqui, K Kotecha, A M Salicioni, V Kalia, J F Murray, C A Wilson. Serotonin inhibits luteinizing hormone release via 5-HT1A receptors in the zona incerta of ovariectomised, anaesthetised rats primed with steroids.
Neuroendocrinology.
2000 Nov; 72(5):272-83. doi:
10.1159/000054596. [PMID: 11124584] - P Soares-da-Silva, M A Vieira-Coelho, M Pestana. Antagonistic actions of renal dopamine and 5-hydroxytryptamine: endogenous 5-hydroxytryptamine, 5-HT1A receptors and antinatriuresis during high sodium intake.
British journal of pharmacology.
1996 Mar; 117(6):1193-8. doi:
10.1111/j.1476-5381.1996.tb16715.x. [PMID: 8882615] - P Soares-da-Silva, P C Pinto-do-O, A M Bertorello. Antagonistic actions of renal dopamine and 5-hydroxytryptamine: increase in Na+, K(+)-ATPase activity in renal proximal tubules via activation of 5-HT1A receptors.
British journal of pharmacology.
1996 Mar; 117(6):1199-203. doi:
10.1111/j.1476-5381.1996.tb16716.x. [PMID: 8882616] - E Przegaliński, M Filip, M Bijak, K Wedzony, B Budziszewska, K Tokarski, M Maćkowiak, K Fijał. MP-3022, a new putative antagonist at pre- and postsynaptic 5-HT1A receptors.
Polish journal of pharmacology.
1996 Jan; 48(1):13-22. doi:
NULL. [PMID: 9112623] - D J Critchley, V C Middlefell, C W Liddle, N D Foden, C T Dourish. Effects of the selective 5-HT1A receptor antagonist WAY100135 and its enantiomers on 8-OH-DPAT-induced hyperglycaemia in conscious rats.
European journal of pharmacology.
1994 Mar; 254(1-2):133-9. doi:
10.1016/0014-2999(94)90380-8. [PMID: 8206109]