4-P-PDOT (BioDeep_00001875887)
代谢物信息卡片
化学式: C19H21NO (279.1623056)
中文名称: 4-P-PDOT
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CCC(=O)NC1CC(C2=CC=CC=C2C1)C3=CC=CC=C3
InChI: InChI=1S/C19H21NO/c1-2-19(21)20-16-12-15-10-6-7-11-17(15)18(13-16)14-8-4-3-5-9-14/h3-11,16,18H,2,12-13H2,1H3,(H,20,21)
数据库引用编号
5 个数据库交叉引用编号
- ChEBI: CHEBI:110160
- PubChem: 3976006
- ChEMBL: CHEMBL285718
- CAS: 134865-74-0
- CAS: 620170-78-7
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- Shou-Long Deng, Tie-Cheng Sun, Kun Yu, Zhi-Peng Wang, Bao-Lu Zhang, Yan Zhang, Xiu-Xia Wang, Zheng-Xing Lian, Yi-Xun Liu. Melatonin reduces oxidative damage and upregulates heat shock protein 90 expression in cryopreserved human semen.
Free radical biology & medicine.
2017 12; 113(?):347-354. doi:
10.1016/j.freeradbiomed.2017.10.342
. [PMID: 29051117] - Wucai Yang, Keqiong Tang, Yaning Wang, Yingying Zhang, Linsen Zan. Melatonin promotes triacylglycerol accumulation via MT2 receptor during differentiation in bovine intramuscular preadipocytes.
Scientific reports.
2017 11; 7(1):15080. doi:
10.1038/s41598-017-12780-y
. [PMID: 29118419] - Yajie Liu, Cheng Ni, Zhengqian Li, Ning Yang, Yang Zhou, Xiaoying Rong, Min Qian, Dehua Chui, Xiangyang Guo. Prophylactic Melatonin Attenuates Isoflurane-Induced Cognitive Impairment in Aged Rats through Hippocampal Melatonin Receptor 2 - cAMP Response Element Binding Signalling.
Basic & clinical pharmacology & toxicology.
2017 Mar; 120(3):219-226. doi:
10.1111/bcpt.12652
. [PMID: 27515785] - Fuju Chen, Aikebaier Reheman, Jing Cao, Zixu Wang, Yulan Dong, Yuxian Zhang, Yaoxing Chen. Effect of melatonin on monochromatic light-induced T-lymphocyte proliferation in the thymus of chickens.
Journal of photochemistry and photobiology. B, Biology.
2016 Aug; 161(?):9-16. doi:
10.1016/j.jphotobiol.2016.05.001
. [PMID: 27203566] - M Juszczak, M Roszczyk, E Kowalczyk, B Stempniak. The influence od melatonin receptors antagonists, luzindole and 4-phenyl-2-propionamidotetralin (4-P-PDOT), on melatonin-dependent vasopressin and adrenocorticotropic hormone (ACTH) release from the rat hypothalamo-hypophysial system. In vitro and in vivo studies.
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society.
2014 Dec; 65(6):777-84. doi:
NULL
. [PMID: 25554981] - Tracy A Bedrosian, Kamillya L Herring, James C Walton, Laura K Fonken, Zachary M Weil, Randy J Nelson. Evidence for feedback control of pineal melatonin secretion.
Neuroscience letters.
2013 May; 542(?):123-5. doi:
10.1016/j.neulet.2013.03.021
. [PMID: 23528860] - Ina Bähr, Eckhard Mühlbauer, Elke Albrecht, Elmar Peschke. Evidence of the receptor-mediated influence of melatonin on pancreatic glucagon secretion via the Gαq protein-coupled and PI3K signaling pathways.
Journal of pineal research.
2012 Nov; 53(4):390-8. doi:
10.1111/j.1600-079x.2012.01009.x
. [PMID: 22672634] - Anastasia Renzi, Shannon Glaser, Sharon Demorrow, Romina Mancinelli, Fanyin Meng, Antonio Franchitto, Julie Venter, Mellanie White, Heather Francis, Yuyan Han, Domenico Alvaro, Eugenio Gaudio, Guido Carpino, Yoshiyuki Ueno, Paolo Onori, Gianfranco Alpini. Melatonin inhibits cholangiocyte hyperplasia in cholestatic rats by interaction with MT1 but not MT2 melatonin receptors.
American journal of physiology. Gastrointestinal and liver physiology.
2011 Oct; 301(4):G634-43. doi:
10.1152/ajpgi.00206.2011
. [PMID: 21757639] - Gene Chi-Wai Man, William Wei-Jun Wang, Benson Hiu-Yan Yeung, Simon Kwong-Man Lee, Bobby Kin-Ah Ng, Wing-Yin Hung, Jack Ho Wong, Tzi-Bun Ng, Yong Qiu, Jack Chun-Yiu Cheng. Abnormal proliferation and differentiation of osteoblasts from girls with adolescent idiopathic scoliosis to melatonin.
Journal of pineal research.
2010 Aug; 49(1):69-77. doi:
10.1111/j.1600-079x.2010.00768.x
. [PMID: 20524972] - Gabriel F Anhê, Luciana C Caperuto, Marcio Pereira-Da-Silva, Lilian C Souza, A Emiko Hirata, Lício A Velloso, José Cipolla-Neto, Carla R O Carvalho. In vivo activation of insulin receptor tyrosine kinase by melatonin in the rat hypothalamus.
Journal of neurochemistry.
2004 Aug; 90(3):559-66. doi:
10.1111/j.1471-4159.2004.02514.x
. [PMID: 15255933] - Stephen Y W Shiu, In C Law, Kai W Lau, Po C Tam, Andrew W C Yip, Wai T Ng. Melatonin slowed the early biochemical progression of hormone-refractory prostate cancer in a patient whose prostate tumor tissue expressed MT1 receptor subtype.
Journal of pineal research.
2003 Oct; 35(3):177-82. doi:
10.1034/j.1600-079x.2003.00074.x
. [PMID: 12932201] - W F Lubbe. Antihypertensive therapy with timolol and alpha-methyldopa. A double-blind trial in patients with moderately severe hypertension.
South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde.
1976 Feb; 50(9):279-85. doi:
. [PMID: 4898]