N-[4-Chloro-3-(trifluoromethyl)phenyl]-2-ethoxybenzamide (BioDeep_00001875507)
代谢物信息卡片
N-[4-Chloro-3-(trifluoromethyl)phenyl]-2-ethoxybenzamide
化学式: C16H13ClF3NO2 (343.0586864)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CCOC1=CC=CC=C1C(=O)NC2=CC(=C(C=C2)Cl)C(F)(F)F
InChI: InChI=1S/C16H13ClF3NO2/c1-2-23-14-6-4-3-5-11(14)15(22)21-10-7-8-13(17)12(9-10)16(18,19)20/h3-9H,2H2,1H3,(H,21,22)
描述信息
D009676 - Noxae > D011042 - Poisons
D007155 - Immunologic Factors
同义名列表
相关代谢途径
Reactome(0)
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PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Mi-Young Kim, Emil Vergara, Andy Tran, Matthew John Paul, Tae-Ho Kwon, Julian K C Ma, Yong-Suk Jang, Rajko Reljic. Marked enhancement of the immunogenicity of plant-expressed IgG-Fc fusion proteins by inclusion of cholera toxin non-toxic B subunit within the single polypeptide.
Plant biotechnology journal.
2024 May; 22(5):1402-1416. doi:
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Toxins.
2024 Apr; 16(4):. doi:
10.3390/toxins16040194. [PMID: 38668619] - Charlotta Hansson, Cristina Lebrero-Fernández, Karin Schön, Davide Angeletti, Nils Lycke. Tr1 cell-mediated protection against autoimmune disease by intranasal administration of a fusion protein targeting cDC1 cells.
Mucosal immunology.
2023 May; ?(?):. doi:
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ACS synthetic biology.
2022 12; 11(12):3929-3938. doi:
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Analytical chemistry.
2022 11; 94(46):16042-16049. doi:
10.1021/acs.analchem.2c03067. [PMID: 36367338] - Aniruddha Sasmal, Naazneen Khan, Zahra Khedri, Benjamin P Kellman, Saurabh Srivastava, Andrea Verhagen, Hai Yu, Anders Bech Bruntse, Sandra Diaz, Nissi Varki, Travis Beddoe, Adrienne W Paton, James C Paton, Xi Chen, Nathan E Lewis, Ajit Varki. Simple and practical sialoglycan encoding system reveals vast diversity in nature and identifies a universal sialoglycan-recognizing probe derived from AB5 toxin B subunits.
Glycobiology.
2022 11; 32(12):1101-1115. doi:
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Infection and immunity.
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mBio.
2016 12; 7(6):. doi:
10.1128/mbio.02021-16. [PMID: 27999163] - Krishnan Raghunathan, Tiffany H Wong, Daniel J Chinnapen, Wayne I Lencer, Michael G Jobling, Anne K Kenworthy. Glycolipid Crosslinking Is Required for Cholera Toxin to Partition Into and Stabilize Ordered Domains.
Biophysical journal.
2016 Dec; 111(12):2547-2550. doi:
10.1016/j.bpj.2016.11.008. [PMID: 27914621] - Nirmal Marasini, Zeinab G Khalil, Ashwini Kumar Giddam, Khairunnisa Abdul Ghaffar, Waleed M Hussein, Robert J Capon, Michael R Batzloff, Michael F Good, Mariusz Skwarczynski, Istvan Toth. Lipid core peptide/poly(lactic-co-glycolic acid) as a highly potent intranasal vaccine delivery system against Group A streptococcus.
International journal of pharmaceutics.
2016 Nov; 513(1-2):410-420. doi:
10.1016/j.ijpharm.2016.09.057. [PMID: 27659862] - Maria A Gonzalez Porras, Paul N Durfee, Ashley M Gregory, Gary C Sieck, C Jeffrey Brinker, Carlos B Mantilla. A novel approach for targeted delivery to motoneurons using cholera toxin-B modified protocells.
Journal of neuroscience methods.
2016 11; 273(?):160-174. doi:
10.1016/j.jneumeth.2016.09.003. [PMID: 27641118] - Mi-Young Kim, Byeong-Young Kim, Sun-Mi Oh, Rajko Reljic, Yong-Suk Jang, Moon-Sik Yang. Oral immunisation of mice with transgenic rice calli expressing cholera toxin B subunit fused to consensus dengue cEDIII antigen induces antibodies to all four dengue serotypes.
Plant molecular biology.
2016 Oct; 92(3):347-56. doi:
10.1007/s11103-016-0517-0. [PMID: 27566485] - Shruti Chatterjee, M Shamim Hasan Zahid, Sharda Prasad Awasthi, Nityananda Chowdhury, Masahiro Asakura, Atsushi Hinenoya, T Ramamurthy, Emiko Iwaoka, Shunji Aoki, Shinji Yamasaki. In Vitro Inhibition of Cholera Toxin Production in Vibrio cholerae by Methanol Extract of Sweet Fennel Seeds and Its Components.
Japanese journal of infectious diseases.
2016 Sep; 69(5):384-9. doi:
10.7883/yoken.jjid.2015.421. [PMID: 26902215] - Ian Bruzas, Sarah Unser, Sadegh Yazdi, Emilie Ringe, Laura Sagle. Ultrasensitive Plasmonic Platform for Label-Free Detection of Membrane-Associated Species.
Analytical chemistry.
2016 08; 88(16):7968-74. doi:
10.1021/acs.analchem.6b00801. [PMID: 27436204] - Koji Ando, Masashi Tanabe, Kenichi Morigaki. Nanometric Gap Structure with a Fluid Lipid Bilayer for the Selective Transport and Detection of Biological Molecules.
Langmuir : the ACS journal of surfaces and colloids.
2016 08; 32(31):7958-64. doi:
10.1021/acs.langmuir.6b01405. [PMID: 27427950] - Chong-Hua Zhang, Ling-Wei Liu, Ping Liang, Li-Juan Tang, Ru-Qin Yu, Jian-Hui Jiang. Plasmon Coupling Enhanced Raman Scattering Nanobeacon for Single-Step, Ultrasensitive Detection of Cholera Toxin.
Analytical chemistry.
2016 08; 88(15):7447-52. doi:
10.1021/acs.analchem.6b00944. [PMID: 27348262] - M R Kasimov, G F Zakyrjanova, A R Giniatullin, A L Zefirov, A M Petrov. Similar oxysterols may lead to opposite effects on synaptic transmission: Olesoxime versus 5α-cholestan-3-one at the frog neuromuscular junction.
Biochimica et biophysica acta.
2016 Jul; 1861(7):606-16. doi:
10.1016/j.bbalip.2016.04.010. [PMID: 27102612] - Akshay Sridhar, Amit Kumar, Ashok Kumar Dasmahapatra. Multi-scale molecular dynamics study of cholera pentamer binding to a GM1-phospholipid membrane.
Journal of molecular graphics & modelling.
2016 07; 68(?):236-251. doi:
10.1016/j.jmgm.2016.07.007. [PMID: 27474868] - Rouhollah Kazemi, Asal Akhavian, Jafar Amani, Jafar Salimian, Mohammad-Javad Motamedi, Amir Mousavi, Mahyat Jafari, Ali-Hatef Salmanian. Immunogenic properties of trivalent recombinant protein composed of B-subunits of LT, STX-2, and CT toxins.
Microbes and infection.
2016 06; 18(6):421-429. doi:
10.1016/j.micinf.2016.03.001. [PMID: 26970204] - Douglas S Costa, Thiago S L Araújo, Nayara A Sousa, Luan K M Souza, Dvison M Pacífico, Francisca Beatriz M Sousa, Lucas A D Nicolau, Luciano S Chaves, Francisco Clark N Barros, Ana Lúcia P Freitas, Jand Venes R Medeiros. Sulphated Polysaccharide Isolated from the Seaweed Gracilaria caudata Exerts an Antidiarrhoeal Effect in Rodents.
Basic & clinical pharmacology & toxicology.
2016 Jun; 118(6):440-8. doi:
10.1111/bcpt.12531. [PMID: 26582552] - Yong-Sang Ryu, Nathan J Wittenberg, Jeng-Hun Suh, Sang-Wook Lee, Youngjoo Sohn, Sang-Hyun Oh, Atul N Parikh, Sin-Doo Lee. Continuity of Monolayer-Bilayer Junctions for Localization of Lipid Raft Microdomains in Model Membranes.
Scientific reports.
2016 05; 6(?):26823. doi:
10.1038/srep26823. [PMID: 27230411] - Nayara A Sousa, Francisco Clark N Barros, Thiago S L Araújo, Douglas S Costa, Luan Kelves M Souza, Francisca Beatriz M Sousa, Ana Carolina M Leódido, Dvison M Pacífico, Simone de Araújo, Francisco F Bezerra, Ana Lúcia P Freitas, Jand Venes R Medeiros. The efficacy of a sulphated polysaccharide fraction from Hypnea musciformis against diarrhea in rodents.
International journal of biological macromolecules.
2016 May; 86(?):865-75. doi:
10.1016/j.ijbiomac.2016.02.028. [PMID: 26879913] - Josué I Beltrán-López, Andrea Romero-Maldonado, Elizabeth Monreal-Escalante, Bernardo Bañuelos-Hernández, Luz Mt Paz-Maldonado, Sergio Rosales-Mendoza. Chlamydomonas reinhardtii chloroplasts express an orally immunogenic protein targeting the p210 epitope implicated in atherosclerosis immunotherapies.
Plant cell reports.
2016 May; 35(5):1133-41. doi:
10.1007/s00299-016-1946-6. [PMID: 26886711] - Takahiro Yamanaka, Hidekazu Tamauchi, Yusuke Suzuki, Hitoshi Suzuki, Satoshi Horikoshi, Masazumi Terashima, Kazuya Iwabuchi, Sonoko Habu, Ko Okumura, Yasuhiko Tomino. Release from Th1-type immune tolerance in spleen and enhanced production of IL-5 in Peyer's patch by cholera toxin B induce the glomerular deposition of IgA.
Immunobiology.
2016 Apr; 221(4):577-85. doi:
10.1016/j.imbio.2015.12.001. [PMID: 26719095] - Charlotta Hansson, Karin Schön, Irina Kalbina, Åke Strid, Sören Andersson, Maria I Bokarewa, Nils Y Lycke. Feeding transgenic plants that express a tolerogenic fusion protein effectively protects against arthritis.
Plant biotechnology journal.
2016 Apr; 14(4):1106-15. doi:
10.1111/pbi.12479. [PMID: 26403330] - Koji Kashima, Yoshikazu Yuki, Mio Mejima, Shiho Kurokawa, Yuji Suzuki, Satomi Minakawa, Natsumi Takeyama, Yoshiko Fukuyama, Tatsuhiko Azegami, Takeshi Tanimoto, Masaharu Kuroda, Minoru Tamura, Yasuyuki Gomi, Hiroshi Kiyono. Good manufacturing practices production of a purification-free oral cholera vaccine expressed in transgenic rice plants.
Plant cell reports.
2016 Mar; 35(3):667-79. doi:
10.1007/s00299-015-1911-9. [PMID: 26661780] - Patrick Cherubin, Maria Camila Garcia, David Curtis, Christopher B T Britt, John W Craft, Helen Burress, Chris Berndt, Srikar Reddy, Jessica Guyette, Tianyu Zheng, Qun Huo, Beatriz Quiñones, James M Briggs, Ken Teter. Inhibition of Cholera Toxin and Other AB Toxins by Polyphenolic Compounds.
PloS one.
2016; 11(11):e0166477. doi:
10.1371/journal.pone.0166477. [PMID: 27829022] - Humaira Adnan, Zhenbo Zhang, Hyun-Joo Park, Chetankumar Tailor, Clare Che, Mustafa Kamani, George Spitalny, Beth Binnington, Clifford Lingwood. Endoplasmic Reticulum-Targeted Subunit Toxins Provide a New Approach to Rescue Misfolded Mutant Proteins and Revert Cell Models of Genetic Diseases.
PloS one.
2016; 11(12):e0166948. doi:
10.1371/journal.pone.0166948. [PMID: 27935997] - Nolan C Worstell, Pratik Krishnan, Joshua D Weatherston, Hung-Jen Wu. Binding Cooperativity Matters: A GM1-Like Ganglioside-Cholera Toxin B Subunit Binding Study Using a Nanocube-Based Lipid Bilayer Array.
PloS one.
2016; 11(4):e0153265. doi:
10.1371/journal.pone.0153265. [PMID: 27070150] - Wei Deng, Melissa M J Farnham, Ewa M Goldys, Suja Mohammed, Paul M Pilowsky. Gene Interference with Morpholinos in a Gold Nanoparticle-Based Delivery Platform in Rat PC12 Cells.
Journal of biomedical nanotechnology.
2015 Dec; 11(12):2111-23. doi:
10.1166/jbn.2015.2171. [PMID: 26510306] - Yuqi Huo, Xin Wan, Tong Ling, Jie Wu, Zejun Wang, Shengli Meng, Shuo Shen. Prevailing Sydney like Norovirus GII.4 VLPs induce systemic and mucosal immune responses in mice.
Molecular immunology.
2015 Dec; 68(2 Pt A):367-72. doi:
10.1016/j.molimm.2015.09.006. [PMID: 26375574] - Alvaro Toledo, Alberto Pérez, James L Coleman, Jorge L Benach. The lipid raft proteome of Borrelia burgdorferi.
Proteomics.
2015 Nov; 15(21):3662-75. doi:
10.1002/pmic.201500093. [PMID: 26256460] - Wuguang Lu, Lingchong Qiu, Zhanpeng Yan, Zhibing Lin, Meng Cao, Chunping Hu, Zhigang Wang, Jin Wang, Ye Yu, Xiaoyang Cheng, Peng Cao, Rongxiu Li. Cytotoxic T cell responses are enhanced by antigen design involving the presentation of MUC1 peptide on cholera toxin B subunit.
Oncotarget.
2015 Oct; 6(33):34537-48. doi:
10.18632/oncotarget.5307. [PMID: 26417929] - Angela N Pierce, Zhen Zhang, Isabella M Fuentes, Ruipeng Wang, Janelle M Ryals, Julie A Christianson. Neonatal vaginal irritation results in long-term visceral and somatic hypersensitivity and increased hypothalamic-pituitary-adrenal axis output in female mice.
Pain.
2015 Oct; 156(10):2021-2031. doi:
10.1097/j.pain.0000000000000264. [PMID: 26098441] - Jin Su, Alexandra Sherman, Phillip A Doerfler, Barry J Byrne, Roland W Herzog, Henry Daniell. Oral delivery of Acid Alpha Glucosidase epitopes expressed in plant chloroplasts suppresses antibody formation in treatment of Pompe mice.
Plant biotechnology journal.
2015 Oct; 13(8):1023-32. doi:
10.1111/pbi.12413. [PMID: 26053072] - A Maleah Holland, Hayden W Hyatt, Ashley J Smuder, Kurt J Sollanek, Aaron B Morton, Michael D Roberts, Andreas N Kavazis. Influence of endurance exercise training on antioxidant enzymes, tight junction proteins, and inflammatory markers in the rat ileum.
BMC research notes.
2015 Sep; 8(?):514. doi:
10.1186/s13104-015-1500-6. [PMID: 26423686] - Seong-Hoon Yun, Eun-Seon Park, Sung-Won Shin, Mi-Ha Ju, Jin-Yeong Han, Jin-Sook Jeong, Sung-Hyun Kim, Valentin A Stonik, Jong-Young Kwak, Joo-In Park. By activating Fas/ceramide synthase 6/p38 kinase in lipid rafts, stichoposide D inhibits growth of leukemia xenografts.
Oncotarget.
2015 Sep; 6(29):27596-612. doi:
10.18632/oncotarget.4820. [PMID: 26318294] - Huijiao Sun, Licui Chen, Lianghui Gao, Weihai Fang. Nanodomain Formation of Ganglioside GM1 in Lipid Membrane: Effects of Cholera Toxin-Mediated Cross-Linking.
Langmuir : the ACS journal of surfaces and colloids.
2015 Aug; 31(33):9105-14. doi:
10.1021/acs.langmuir.5b01866. [PMID: 26250646] - J Majewski, S André, E Jones, E Chi, H-J Gabius. X-ray reflectivity and grazing incidence diffraction studies of interaction between human adhesion/growth-regulatory galectin-1 and DPPE-GM1 lipid monolayer at an air/water interface.
Biochemistry. Biokhimiia.
2015 Jul; 80(7):943-56. doi:
10.1134/s0006297915070135. [PMID: 26542007] - Vinh Van Hoang, Yanshuang Zou, Kentaro Kurata, Keiichi Enomoto. Expression of recombinant T-cell epitopes of major Japanese cedar pollen allergens fused with cholera toxin B subunit in Escherichia coli.
Protein expression and purification.
2015 May; 109(?):62-9. doi:
10.1016/j.pep.2015.02.001. [PMID: 25665505] - Tatsuhiko Azegami, Hiroshi Itoh, Hiroshi Kiyono, Yoshikazu Yuki. Novel transgenic rice-based vaccines.
Archivum immunologiae et therapiae experimentalis.
2015 Apr; 63(2):87-99. doi:
10.1007/s00005-014-0303-0. [PMID: 25027548] - Boying Liang, Yue Ju, James R Joubert, Erin J Kaleta, Rodrigo Lopez, Ian W Jones, Henry K Hall, Saliya N Ratnayaka, Vicki H Wysocki, S Scott Saavedra. Label-free detection and identification of protein ligands captured by receptors in a polymerized planar lipid bilayer using MALDI-TOF MS.
Analytical and bioanalytical chemistry.
2015 Apr; 407(10):2777-89. doi:
10.1007/s00216-015-8508-6. [PMID: 25694144] - Valérie Nicolas, Vanessa Liévin-Le Moal. Antisecretory factor peptide AF-16 inhibits the secreted autotransporter toxin-stimulated transcellular and paracellular passages of fluid in cultured human enterocyte-like cells.
Infection and immunity.
2015 Mar; 83(3):907-22. doi:
10.1128/iai.02759-14. [PMID: 25534938] - M Andreassen, T Bøhn, O-G Wikmark, J Van den Berg, M Løvik, T Traavik, U C Nygaard. Cry1Ab protein from Bacillus thuringiensis and MON810 cry1Ab-transgenic maize exerts no adjuvant effect after airway exposure.
Scandinavian journal of immunology.
2015 Mar; 81(3):192-200. doi:
10.1111/sji.12269. [PMID: 25564738] - Koji Kashima, Mio Mejima, Shiho Kurokawa, Masaharu Kuroda, Hiroshi Kiyono, Yoshikazu Yuki. Comparative whole-genome analyses of selection marker-free rice-based cholera toxin B-subunit vaccine lines and wild-type lines.
BMC genomics.
2015 Feb; 16(?):48. doi:
10.1186/s12864-015-1285-y. [PMID: 25653106]