1H-Imidazole-4-ethanamine, N-methyl- (BioDeep_00001875386)

   


代谢物信息卡片


1H-Imidazole-4-ethanamine, N-methyl-

化学式: C6H11N3 (125.0952926)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CNCCC1=CN=CN1
InChI: InChI=1S/C6H11N3/c1-7-3-2-6-4-8-5-9-6/h4-5,7H,2-3H2,1H3,(H,8,9)

描述信息

同义名列表

1 个代谢物同义名

1H-Imidazole-4-ethanamine, N-methyl-



数据库引用编号

3 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

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PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Mariah J Frank, Mohammad R Khattab, Robert W Wills, Todd M Archer, Andrew J Mackin, Jan S Suchodolski, Jonathan A Lidbury, Joerg M Steiner, Alyssa M Sullivant, John M Thomason. Effects of leukoreduction on N-methylhistamine concentration in stored units of canine whole blood. American journal of veterinary research. 2021 Nov; 82(11):890-896. doi: 10.2460/ajvr.82.11.890. [PMID: 34669495]
  • Catherine R Weiler. How good are mast cell mediators?. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology. 2021 10; 127(4):410-411. doi: 10.1016/j.anai.2021.07.016. [PMID: 34303837]
  • Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome. Cell reports. 2021 04; 35(4):109040. doi: 10.1016/j.celrep.2021.109040. [PMID: 33910017]
  • Joseph H Butterfield. Survey of Mast Cell Mediator Levels from Patients Presenting with Symptoms of Mast Cell Activation. International archives of allergy and immunology. 2020; 181(1):43-50. doi: 10.1159/000503964. [PMID: 31722348]
  • Joseph Cyrus Parambeth, Franklin R López, Rosana Lopez, Sarah B Keyser, Jonathan A Lidbury, Jan S Suchodolski, Jörg M Steiner. Fecal Concentrations of N-methylhistamine in Common Marmosets (Callithrix jacchus). Comparative medicine. 2019 04; 69(2):130-134. doi: 10.30802/aalas-cm-18-000040. [PMID: 30803469]
  • Leona W Ayers, Arturo Barbachano-Guerrero, Shane C McAllister, Julie A Ritchie, Elizabeth Asiago-Reddy, Linda C Bartlett, Ethel Cesarman, Dongliang Wang, Rosemary Rochford, Jeffrey N Martin, Christine A King. Mast Cell Activation and KSHV Infection in Kaposi Sarcoma. Clinical cancer research : an official journal of the American Association for Cancer Research. 2018 10; 24(20):5085-5097. doi: 10.1158/1078-0432.ccr-18-0873. [PMID: 30084838]
  • Bhavisha Patel, Rohit Divekar. Urinary N-methyl histamine levels relate to the presence of angioedema and decrease with the duration of chronic urticaria. The journal of allergy and clinical immunology. In practice. 2017 Jan; 5(1):201-203. doi: 10.1016/j.jaip.2016.09.036. [PMID: 27838330]
  • R Divekar, J Butterfield. Urinary 11β-PGF2α and N-methyl histamine correlate with bone marrow biopsy findings in mast cell disorders. Allergy. 2015 Oct; 70(10):1230-8. doi: 10.1111/all.12668. [PMID: 26095439]
  • Milda Vysniauskaite, Hans-Jörg Hertfelder, Johannes Oldenburg, Peter Dreßen, Stefan Brettner, Jürgen Homann, Gerhard J Molderings. Determination of plasma heparin level improves identification of systemic mast cell activation disease. PloS one. 2015; 10(4):e0124912. doi: 10.1371/journal.pone.0124912. [PMID: 25909362]
  • Kristin P Anfinsen, Nora Berghoff, Simon L Priestnall, Jan S Suchodolski, Jörg M Steiner, Karin Allenspach. Urinary and faecal N-methylhistamine concentrations do not serve as markers for mast cell activation or clinical disease activity in dogs with chronic enteropathies. Acta veterinaria Scandinavica. 2014 Dec; 56(?):90. doi: 10.1186/s13028-014-0090-y. [PMID: 25528646]
  • Lawrence B Afrin. Mast cell activation syndrome as a significant comorbidity in sickle cell disease. The American journal of the medical sciences. 2014 Dec; 348(6):460-4. doi: 10.1097/maj.0000000000000325. [PMID: 25171546]
  • Nora Berghoff, Steve Hill, Nolie K Parnell, Joanne Mansell, Jan S Suchodolski, Jörg M Steiner. Fecal and urinary N-methylhistamine concentrations in dogs with chronic gastrointestinal disease. Veterinary journal (London, England : 1997). 2014 Sep; 201(3):289-94. doi: 10.1016/j.tvjl.2014.05.016. [PMID: 24907867]
  • Joseph H Butterfield, Catherine R Weiler. Presentation of untreated systemic mastocytosis as recurrent, pulseless-electrical-activity cardiac arrests resistant to cardiac pacemaker. International archives of allergy and immunology. 2014; 163(2):130-4. doi: 10.1159/000356487. [PMID: 24335343]
  • Matthew A Rank, Hirohito Kita, James T Li, Joseph H Butterfield. Systemic reactions to allergen immunotherapy: a role for measuring a PGD2 metabolite?. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology. 2013 Jan; 110(1):57-8. doi: 10.1016/j.anai.2012.10.009. [PMID: 23244662]
  • Joakim Johansson, Emmanuel Bäckryd, Göran Granerus, Folke Sjöberg. Urinary excretion of histamine and methylhistamine after burns. Burns : journal of the International Society for Burn Injuries. 2012 Nov; 38(7):1005-9. doi: 10.1016/j.burns.2012.02.014. [PMID: 22652469]
  • J J van Doormaal, E van der Veer, P C van Voorst Vader, P M Kluin, A B Mulder, S van der Heide, S Arends, J C Kluin-Nelemans, J N G Oude Elberink, J G R de Monchy. Tryptase and histamine metabolites as diagnostic indicators of indolent systemic mastocytosis without skin lesions. Allergy. 2012 May; 67(5):683-90. doi: 10.1111/j.1398-9995.2012.02809.x. [PMID: 22435702]
  • Samar Farha, Jacqueline Sharp, Kewal Asosingh, Margaret Park, Suzy A A Comhair, W H Wilson Tang, Jim Thomas, Carol Farver, Fred Hsieh, James E Loyd, Serpil C Erzurum. Mast cell number, phenotype, and function in human pulmonary arterial hypertension. Pulmonary circulation. 2012 Apr; 2(2):220-8. doi: 10.4103/2045-8932.97609. [PMID: 22837863]
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  • Silke Beermann, Silke Glage, Danny Jonigk, Roland Seifert, Detlef Neumann. Opposite effects of mepyramine on JNJ 7777120-induced amelioration of experimentally induced asthma in mice in sensitization and provocation. PloS one. 2012; 7(1):e30285. doi: 10.1371/journal.pone.0030285. [PMID: 22272324]
  • Anna Sophie Zimmermann, Heike Burhenne, Volkhard Kaever, Roland Seifert, Detlef Neumann. Systematic analysis of histamine and N-methylhistamine concentrations in organs from two common laboratory mouse strains: C57Bl/6 and Balb/c. Inflammation research : official journal of the European Histamine Research Society ... [et al.]. 2011 Dec; 60(12):1153-9. doi: 10.1007/s00011-011-0379-5. [PMID: 21912978]
  • Travis T Wager, Betty A Pettersen, Anne W Schmidt, Douglas K Spracklin, Scot Mente, Todd W Butler, Harry Howard, Daniel J Lettiere, David M Rubitski, Diane F Wong, Frank M Nedza, Frederick R Nelson, Hans Rollema, Jeffrey W Raggon, Jiri Aubrecht, Jody K Freeman, John M Marcek, Julie Cianfrogna, Karen W Cook, Larry C James, Linda A Chatman, Philip A Iredale, Michael J Banker, Michael L Homiski, Jennifer B Munzner, Rama Y Chandrasekaran. Discovery of two clinical histamine H(3) receptor antagonists: trans-N-ethyl-3-fluoro-3-[3-fluoro-4-(pyrrolidinylmethyl)phenyl]cyclobutanecarboxamide (PF-03654746) and trans-3-fluoro-3-[3-fluoro-4-(pyrrolidin-1-ylmethyl)phenyl]-N-(2-methylpropyl)cyclobutanecarboxamide (PF-03654764). Journal of medicinal chemistry. 2011 Nov; 54(21):7602-20. doi: 10.1021/jm200939b. [PMID: 21928839]
  • M Raithel, Y Zopf, S Kimpel, A Naegel, G J Molderings, F Buchwald, H W Schultis, J Kressel, E G Hahn, P Konturek. The measurement of leukotrienes in urine as diagnostic option in systemic mastocytosis. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society. 2011 Aug; 62(4):469-72. doi: NULL. [PMID: 22100848]
  • Lawrence B Afrin. Polycythemia from mast cell activation syndrome: lessons learned. The American journal of the medical sciences. 2011 Jul; 342(1):44-9. doi: 10.1097/maj.0b013e31821d41dd. [PMID: 21642812]
  • T Frieling, K Meis, U W Kolck, J Homann, A Hülsdonk, U Haars, H-J Hertfelder, J Oldenburg, H Seidel, G J Molderings. Evidence for mast cell activation in patients with therapy-resistant irritable bowel syndrome. Zeitschrift fur Gastroenterologie. 2011 Feb; 49(2):191-4. doi: 10.1055/s-0029-1245707. [PMID: 21298604]
  • Ugo Da Broi, Carlo Moreschi. Post-mortem diagnosis of anaphylaxis: A difficult task in forensic medicine. Forensic science international. 2011 Jan; 204(1-3):1-5. doi: 10.1016/j.forsciint.2010.04.039. [PMID: 20684869]
  • Don Otter, Mingshu Cao, Hui-Ming Lin, Karl Fraser, Shelley Edmunds, Geoff Lane, Daryl Rowan. Identification of urinary biomarkers of colon inflammation in IL10-/- mice using Short-Column LCMS metabolomics. Journal of biomedicine & biotechnology. 2011; 2011(?):974701. doi: 10.1155/2011/974701. [PMID: 21188174]
  • Sj Wadsworth, Dd Sin, Dr Dorscheid. Clinical update on the use of biomarkers of airway inflammation in the management of asthma. Journal of asthma and allergy. 2011; 4(?):77-86. doi: 10.2147/jaa.s15081. [PMID: 21792321]
  • Joseph H Butterfield. Increased leukotriene E4 excretion in systemic mastocytosis. Prostaglandins & other lipid mediators. 2010 Jun; 92(1-4):73-6. doi: 10.1016/j.prostaglandins.2010.03.003. [PMID: 20380889]
  • Marjolein L Donker, Jasper J van Doormaal, Frederiek F van Doormaal, Philip M Kluin, Eveline van der Veer, Jan G R de Monchy, Ido P Kema, Hanneke C Kluin-Nelemans. Biochemical markers predictive for bone marrow involvement in systemic mastocytosis. Haematologica. 2008 Jan; 93(1):120-3. doi: 10.3324/haematol.11558. [PMID: 18166795]
  • S Kimpel, A Nägel, C Kestler, B Backhaus, S Straube, F Buchwald, H W Schultis, J Kressel, E G Hahn, M Raithel. Evaluation of urinary N-methylhistamine excretion during a long-term follow up of patients with inactive Crohn's disease. Inflammation research : official journal of the European Histamine Research Society ... [et al.]. 2007 Apr; 56 Suppl 1(?):S61-2. doi: 10.1007/s00011-006-0530-x. [PMID: 17806183]
  • Brian A Hall, Evangelo Frigas, Damir Matesic, Michael D Gillett, Juraj Sprung. Case report: intraoperative anaphylactoid reaction and hydroxyethyl starch in balanced electrolyte solution (Hextend). Canadian journal of anaesthesia = Journal canadien d'anesthesie. 2006 Oct; 53(10):989-93. doi: 10.1007/bf03022527. [PMID: 16987853]
  • Leah M Lamale, Susan K Lutgendorf, M Bridget Zimmerman, Karl J Kreder. Interleukin-6, histamine, and methylhistamine as diagnostic markers for interstitial cystitis. Urology. 2006 Oct; 68(4):702-6. doi: 10.1016/j.urology.2006.04.033. [PMID: 17070335]
  • Helga J Droogendijk, Hanneke J C Kluin-Nelemans, Jaap J van Doormaal, Arnold P Oranje, Arjan A van de Loosdrecht, Paul L A van Daele. Imatinib mesylate in the treatment of systemic mastocytosis: a phase II trial. Cancer. 2006 Jul; 107(2):345-51. doi: 10.1002/cncr.21996. [PMID: 16779792]
  • Satish R Raj. The Postural Tachycardia Syndrome (POTS): pathophysiology, diagnosis & management. Indian pacing and electrophysiology journal. 2006 Apr; 6(2):84-99. doi: NULL. [PMID: 16943900]
  • Hans Jurgen Hoffmann, Tina Skjold, Martin Raithel, Katja Adolf, Ole Hilberg, Ronald Dahl. Response of respiratory flour allergics in an ingested flour challenge may involve plasmacytoid dendritic cells, CD25+ and CD152+ T cells. International archives of allergy and immunology. 2006; 140(3):252-60. doi: 10.1159/000093251. [PMID: 16691032]
  • A W van Toorenenbergen, A P Oranje. Comparison of serum tryptase and urine N-methylhistamine in patients with suspected mastocytosis. Clinica chimica acta; international journal of clinical chemistry. 2005 Sep; 359(1-2):72-7. doi: 10.1016/j.cccn.2005.03.041. [PMID: 15913591]
  • Cyndya Shibao, Carmen Arzubiaga, L Jackson Roberts, Satish Raj, Bonnie Black, Paul Harris, Italo Biaggioni. Hyperadrenergic postural tachycardia syndrome in mast cell activation disorders. Hypertension (Dallas, Tex. : 1979). 2005 Mar; 45(3):385-90. doi: 10.1161/01.hyp.0000158259.68614.40. [PMID: 15710782]
  • Joseph H Butterfield, Ayalew Tefferi, Gerald F Kozuh. Successful treatment of systemic mastocytosis with high-dose interferon-alfa: long-term follow-up of a case. Leukemia research. 2005 Feb; 29(2):131-4. doi: 10.1016/j.leukres.2004.05.003. [PMID: 15607359]
  • Deborah R Erickson, John E Tomaszewski, Allen R Kunselman, Christina M Bentley, Kenneth M Peters, Eric S Rovner, Laurence M Demers, Marcia A Wheeler, Susan K Keay. Do the National Institute of Diabetes and Digestive and Kidney Diseases cystoscopic criteria associate with other clinical and objective features of interstitial cystitis?. The Journal of urology. 2005 Jan; 173(1):93-7. doi: 10.1097/01.ju.0000146466.71311.ab. [PMID: 15592040]
  • Deborah R Erickson, Allen R Kunselman, Christina M Bentley, Kenneth M Peters, Eric S Rovner, Laurence M Demers, John E Tomaszewski. Is urine methylhistamine a useful marker for interstitial cystitis?. The Journal of urology. 2004 Dec; 172(6 Pt 1):2256-60. doi: 10.1097/01.ju.0000140956.25590.98. [PMID: 15538243]
  • Shigeyuki Oguri, Yuko Maeda, Aki Mizusawa. On-column derivatization-capillary electrochromatography with o-phthalaldehyde/alkylthiol for assay of biogenic amines. Journal of chromatography. A. 2004 Jul; 1044(1-2):271-6. doi: 10.1016/j.chroma.2004.04.053. [PMID: 15354448]
  • Taina Arvola, Eeva Moilanen, Risto Vuento, Erika Isolauri. Weaning to hypoallergenic formula improves gut barrier function in breast-fed infants with atopic eczema. Journal of pediatric gastroenterology and nutrition. 2004 Jan; 38(1):92-6. doi: 10.1097/00005176-200401000-00020. [PMID: 14676602]
  • Xiaowei Xu, Benjamin Solky, Rosalie Elenitsas, George Cotsarelis. Scarring alopecia associated with mastocytosis. Journal of cutaneous pathology. 2003 Oct; 30(9):561-5. doi: 10.1034/j.1600-0560.2003.00093.x. [PMID: 14507404]
  • Violina Lozeva, Juhani Tarhanen, Martti Attila, Pekka T Männistö, Leena Tuomisto. Brain histamine and histamine H3 receptors following repeated L-histidine administration in rats. Life sciences. 2003 Aug; 73(12):1491-503. doi: 10.1016/s0024-3205(03)00478-8. [PMID: 12865089]
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  • Jingcai Chen, Changlu Liu, Timothy W Lovenberg. Molecular and pharmacological characterization of the mouse histamine H3 receptor. European journal of pharmacology. 2003 Apr; 467(1-3):57-65. doi: 10.1016/s0014-2999(03)01635-2. [PMID: 12706455]
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