(E)-4-oxohex-2-enal (BioDeep_00001875311)

   


代谢物信息卡片


(E)-4-oxohex-2-enal

化学式: C6H8O2 (112.05242679999999)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CCC(=O)C=CC=O
InChI: InChI=1S/C6H8O2/c1-2-6(8)4-3-5-7/h3-5H,2H2,1H3/b4-3+

描述信息

同义名列表

1 个代谢物同义名

(E)-4-oxohex-2-enal



数据库引用编号

4 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

2 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Pei-Hsin Chou, Shinji Kageyama, Shun Matsuda, Keishi Kanemoto, Yoshiaki Sasada, Megumi Oka, Kazuya Shinmura, Hiroki Mori, Kazuaki Kawai, Hiroshi Kasai, Haruhiko Sugimura, Tomonari Matsuda. Detection of lipid peroxidation-induced DNA adducts caused by 4-oxo-2(E)-nonenal and 4-oxo-2(E)-hexenal in human autopsy tissues. Chemical research in toxicology. 2010 Sep; 23(9):1442-8. doi: 10.1021/tx100047d. [PMID: 20849149]
  • Eric K Long, Matthew J Picklo. Trans-4-hydroxy-2-hexenal, a product of n-3 fatty acid peroxidation: make some room HNE... Free radical biology & medicine. 2010 Jul; 49(1):1-8. doi: 10.1016/j.freeradbiomed.2010.03.015. [PMID: 20353821]
  • Kazuaki Kawai, Pei-Hsin Chou, Tomonari Matsuda, Masaaki Inoue, Kaisa Aaltonen, Kirsti Savela, Yoshikazu Takahashi, Hikaru Nakamura, Tomoyuki Kimura, Takumi Watanabe, Ryuichi Sawa, Kazuyuki Dobashi, Yun-Shan Li, Hiroshi Kasai. DNA modifications by the omega-3 lipid peroxidation-derived mutagen 4-oxo-2-hexenal in vitro and their analysis in mouse and human DNA. Chemical research in toxicology. 2010 Mar; 23(3):630-6. doi: 10.1021/tx9003819. [PMID: 20055452]
  • Hiroshi Kasai, Kazuaki Kawai. 4-oxo-2-hexenal, a mutagen formed by omega-3 fat peroxidation: occurrence, detection and adduct formation. Mutation research. 2008 Jul; 659(1-2):56-9. doi: 10.1016/j.mrrev.2008.02.003. [PMID: 18406660]
  • Shinji Takasu, Tetsuya Tsukamoto, Akihiro Hirata, Kazuaki Kawai, Takeshi Toyoda, Hisayo Ban, Hiroki Sakai, Tokuma Yanai, Toshiaki Masegi, Hiroshi Kasai, Masae Tatematsu. Lack of initiation activity of 4-oxo-2-hexenal, a peroxidation product generated from omega-3 polyunsaturated fatty acids, in an in vivo five-week liver assay. Asian Pacific journal of cancer prevention : APJCP. 2007 Jul; 8(3):372-4. doi: ". [PMID: 18159970]
  • Kazuaki Kawai, Koji Matsuno, Hiroshi Kasai. Detection of 4-oxo-2-hexenal, a novel mutagenic product of lipid peroxidation, in human diet and cooking vapor. Mutation research. 2006 Feb; 603(2):186-92. doi: 10.1016/j.mrgentox.2005.11.012. [PMID: 16423557]
  • Muneyuki Maekawa, Kazuaki Kawai, Yoshikazu Takahashi, Hikaru Nakamura, Takumi Watanabe, Ryuichi Sawa, Kenji Hachisuka, Hiroshi Kasai. Identification of 4-oxo-2-hexenal and other direct mutagens formed in model lipid peroxidation reactions as dGuo adducts. Chemical research in toxicology. 2006 Jan; 19(1):130-8. doi: 10.1021/tx050236m. [PMID: 16411666]
  • Hiroshi Kasai, Muneyuki Maekawa, Kazuaki Kawai, Kenji Hachisuka, Yoshikazu Takahashi, Hikaru Nakamura, Ryuichi Sawa, Saburo Matsui, Tomonari Matsuda. 4-oxo-2-hexenal, a mutagen formed by omega-3 fat peroxidation, causes DNA adduct formation in mouse organs. Industrial health. 2005 Oct; 43(4):699-701. doi: 10.2486/indhealth.43.699. [PMID: 16294926]