N-Acetyl-3-chloro-6H-benzo[b][1,4]benzoxazepine-5-carbohydrazide (BioDeep_00001875259)

   


代谢物信息卡片


N-Acetyl-3-chloro-6H-benzo[b][1,4]benzoxazepine-5-carbohydrazide

化学式: C16H14ClN3O3 (331.07236439999997)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC(=O)NNC(=O)N1CC2=CC=CC=C2OC3=C1C=C(C=C3)Cl
InChI: InChI=1S/C16H14ClN3O3/c1-10(21)18-19-16(22)20-9-11-4-2-3-5-14(11)23-15-7-6-12(17)8-13(15)20/h2-8H,9H2,1H3,(H,18,21)(H,19,22)

描述信息

D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006727 - Hormone Antagonists > D011448 - Prostaglandin Antagonists

同义名列表

1 个代谢物同义名

N-Acetyl-3-chloro-6H-benzo[b][1,4]benzoxazepine-5-carbohydrazide



数据库引用编号

5 个数据库交叉引用编号

分类词条

相关代谢途径

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代谢反应

0 个相关的代谢反应过程信息。

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BioCyc(0)

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Plant Reactome(0)

INOH(0)

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COVID-19 Disease Map(0)

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0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

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文献列表

  • Jean-Claude Kresse, Henricus A M Mutsaers, Michael Schou Jensen, Stine Julie Tingskov, Mia Gebauer Madsen, Lene N Nejsum, Helle Praetorius, Rikke Nørregaard. EP1 receptor antagonism mitigates early and late stage renal fibrosis. Acta physiologica (Oxford, England). 2022 03; 234(3):e13780. doi: 10.1111/apha.13780. [PMID: 34989478]
  • Xu Chen, Jun Yin, Yuyin Xu, Zhi Qiu, Jing Liu, Xiaolan Chen. Effect of selective inhibition or activation of PGE2 EP1 receptor on glomerulosclerosis. Molecular medicine reports. 2020 Oct; 22(4):2887-2895. doi: 10.3892/mmr.2020.11353. [PMID: 32700746]
  • F M Pecanha, G A Wiggers, A M Briones, J V Perez-Giron, M Miguel, A B Garcia-Redondo, D V Vassallo, M J Alonso, M Salaices. The role of cyclooxygenase (COX)-2 derived prostanoids on vasoconstrictor responses to phenylephrine is increased by exposure to low mercury concentration. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society. 2010 Feb; 61(1):29-36. doi: . [PMID: 20228412]
  • Micaela Zonta, Annalisa Sebelin, Sara Gobbo, Tommaso Fellin, Tullio Pozzan, Giorgio Carmignoto. Glutamate-mediated cytosolic calcium oscillations regulate a pulsatile prostaglandin release from cultured rat astrocytes. The Journal of physiology. 2003 Dec; 553(Pt 2):407-14. doi: 10.1113/jphysiol.2003.046706. [PMID: 14500777]
  • Grazia Tamma, Burkhard Wiesner, Jens Furkert, Daniel Hahm, Alexander Oksche, Michael Schaefer, Giovanna Valenti, Walter Rosenthal, Enno Klussmann. The prostaglandin E2 analogue sulprostone antagonizes vasopressin-induced antidiuresis through activation of Rho. Journal of cell science. 2003 Aug; 116(Pt 16):3285-94. doi: 10.1242/jcs.00640. [PMID: 12829746]
  • Najam A Sharif, Terry L Davis. Cloned human EP1 prostanoid receptor pharmacology characterized using radioligand binding techniques. The Journal of pharmacy and pharmacology. 2002 Apr; 54(4):539-47. doi: 10.1211/0022357021778655. [PMID: 11999132]
  • L E Anderson, M K Schultz, M C Wiltbank. Prostaglandin moieties that determine receptor binding specificity in the bovine corpus luteum. Journal of reproduction and fertility. 1999 May; 116(1):133-41. doi: 10.1530/jrf.0.1160133. [PMID: 10505064]
  • Y Boie, R Stocco, N Sawyer, D M Slipetz, M D Ungrin, F Neuschäfer-Rube, G P Püschel, K M Metters, M Abramovitz. Molecular cloning and characterization of the four rat prostaglandin E2 prostanoid receptor subtypes. European journal of pharmacology. 1997 Dec; 340(2-3):227-41. doi: 10.1016/s0014-2999(97)01383-6. [PMID: 9537820]
  • K Yokotani, M Nishihara, Y Murakami, T Hasegawa, Y Okuma, Y Osumi. Elevation of plasma noradrenaline levels in urethane-anaesthetized rats by activation of central prostanoid EP3 receptors. British journal of pharmacology. 1995 Jun; 115(4):672-6. doi: 10.1111/j.1476-5381.1995.tb14985.x. [PMID: 7582489]
  • L Abelli, F Nappi, F Perretti, C A Maggi, S Manzini, A Giachetti. Microvascular leakage induced by substance P in rat urinary bladder: involvement of cyclo-oxygenase metabolites of arachidonic acid. Journal of autonomic pharmacology. 1992 Aug; 12(4):269-76. doi: 10.1111/j.1474-8673.1992.tb00341.x. [PMID: 1380964]
  • Y Kimoto, C E Constantinou. Regional effects of indomethacin, acetylsalicylic acid and SC-19220 on the contractility of rabbit renal pelvis (pacemaker regions and pelviureteric junction). The Journal of urology. 1991 Aug; 146(2):433-8. doi: 10.1016/s0022-5347(17)37819-9. [PMID: 1677433]
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  • L Pons, M T Droy-Lefaix, P Braquet, L Buéno. Involvement of platelet-activating factor (PAF) in endotoxin-induced intestinal motor disturbances in rats. Life sciences. 1989; 45(6):533-41. doi: 10.1016/0024-3205(89)90104-5. [PMID: 2570338]
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