9h-hexadecafluorononanoic acid (BioDeep_00001875242)
代谢物信息卡片
2,2,3,3,4,4,5,5,6,6,7,7,8,8,9,9-Hexadecafluorononanoic acid
化学式: C9H2F16O2 (445.97993039999994)
中文名称: 9H-全氟壬酸
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C(C(C(C(C(C(C(C(C(=O)O)(F)F)(F)F)(F)F)(F)F)(F)F)(F)F)(F)F)(F)F
InChI: InChI=1S/C9H2F16O2/c10-1(11)3(12,13)5(16,17)7(20,21)9(24,25)8(22,23)6(18,19)4(14,15)2(26)27/h1H,(H,26,27)
描述信息
同义名列表
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Ann M Vuong, Kimberly Yolton, Changchun Xie, Kim N Dietrich, Joseph M Braun, Glenys M Webster, Antonia M Calafat, Bruce P Lanphear, Aimin Chen. Childhood exposure to per- and polyfluoroalkyl substances (PFAS) and neurobehavioral domains in children at age 8 years.
Neurotoxicology and teratology.
2021 Nov; 88(?):107022. doi:
10.1016/j.ntt.2021.107022. [PMID: 34438039] - Kelsey E Barton, Anne P Starling, Christopher P Higgins, Carrie A McDonough, Antonia M Calafat, John L Adgate. Sociodemographic and behavioral determinants of serum concentrations of per- and polyfluoroalkyl substances in a community highly exposed to aqueous film-forming foam contaminants in drinking water.
International journal of hygiene and environmental health.
2020 01; 223(1):256-266. doi:
10.1016/j.ijheh.2019.07.012. [PMID: 31444118] - Cyntia B Manzano-Salgado, Berit Granum, Maria-Jose Lopez-Espinosa, Ferran Ballester, Carmen Iñiguez, Mireia Gascón, David Martínez, Mònica Guxens, Mikel Basterretxea, Carlos Zabaleta, Thomas Schettgen, Jordi Sunyer, Martine Vrijheid, Maribel Casas. Prenatal exposure to perfluoroalkyl substances, immune-related outcomes, and lung function in children from a Spanish birth cohort study.
International journal of hygiene and environmental health.
2019 07; 222(6):945-954. doi:
10.1016/j.ijheh.2019.06.005. [PMID: 31262703] - Sharon K Sagiv, Sheryl L Rifas-Shiman, Abby F Fleisch, Thomas F Webster, Antonia M Calafat, Xiaoyun Ye, Matthew W Gillman, Emily Oken. Early-Pregnancy Plasma Concentrations of Perfluoroalkyl Substances and Birth Outcomes in Project Viva: Confounded by Pregnancy Hemodynamics?.
American journal of epidemiology.
2018 04; 187(4):793-802. doi:
10.1093/aje/kwx332. [PMID: 29155920] - Lisa B Rokoff, Sheryl L Rifas-Shiman, Brent A Coull, Andres Cardenas, Antonia M Calafat, Xiaoyun Ye, Alexandros Gryparis, Joel Schwartz, Sharon K Sagiv, Diane R Gold, Emily Oken, Abby F Fleisch. Cumulative exposure to environmental pollutants during early pregnancy and reduced fetal growth: the Project Viva cohort.
Environmental health : a global access science source.
2018 02; 17(1):19. doi:
10.1186/s12940-018-0363-4. [PMID: 29458383] - Nuria Matilla-Santander, Damaskini Valvi, Maria-Jose Lopez-Espinosa, Cyntia B Manzano-Salgado, Ferran Ballester, Jesús Ibarluzea, Loreto Santa-Marina, Thomas Schettgen, Mònica Guxens, Jordi Sunyer, Martine Vrijheid. Exposure to Perfluoroalkyl Substances and Metabolic Outcomes in Pregnant Women: Evidence from the Spanish INMA Birth Cohorts.
Environmental health perspectives.
2017 11; 125(11):117004. doi:
10.1289/ehp1062. [PMID: 29135438] - Cyntia B Manzano-Salgado, Maribel Casas, Maria-Jose Lopez-Espinosa, Ferran Ballester, Carmen Iñiguez, David Martinez, Olga Costa, Loreto Santa-Marina, Eva Pereda-Pereda, Thomas Schettgen, Jordi Sunyer, Martine Vrijheid. Prenatal exposure to perfluoroalkyl substances and birth outcomes in a Spanish birth cohort.
Environment international.
2017 11; 108(?):278-284. doi:
10.1016/j.envint.2017.09.006. [PMID: 28917208] - Anne P Starling, John L Adgate, Richard F Hamman, Katerina Kechris, Antonia M Calafat, Xiaoyun Ye, Dana Dabelea. Perfluoroalkyl Substances during Pregnancy and Offspring Weight and Adiposity at Birth: Examining Mediation by Maternal Fasting Glucose in the Healthy Start Study.
Environmental health perspectives.
2017 06; 125(6):067016. doi:
10.1289/ehp641. [PMID: 28669937] - Abby F Fleisch, Sheryl L Rifas-Shiman, Ana M Mora, Antonia M Calafat, Xiaoyun Ye, Heike Luttmann-Gibson, Matthew W Gillman, Emily Oken, Sharon K Sagiv. Early-Life Exposure to Perfluoroalkyl Substances and Childhood Metabolic Function.
Environmental health perspectives.
2017 03; 125(3):481-487. doi:
10.1289/ehp303. [PMID: 27586368] - Ana María Mora, Emily Oken, Sheryl L Rifas-Shiman, Thomas F Webster, Matthew W Gillman, Antonia M Calafat, Xiaoyun Ye, Sharon K Sagiv. Prenatal Exposure to Perfluoroalkyl Substances and Adiposity in Early and Mid-Childhood.
Environmental health perspectives.
2017 03; 125(3):467-473. doi:
10.1289/ehp246. [PMID: 27352404] - Wen Zhao, Jeremiah D Zitzow, Yi Weaver, David J Ehresman, Shu-Ching Chang, John L Butenhoff, Bruno Hagenbuch. Organic Anion Transporting Polypeptides Contribute to the Disposition of Perfluoroalkyl Acids in Humans and Rats.
Toxicological sciences : an official journal of the Society of Toxicology.
2017 03; 156(1):84-95. doi:
10.1093/toxsci/kfw236. [PMID: 28013215] - Kirsten J Lum, Rajeshwari Sundaram, Dana B Barr, Thomas A Louis, Germaine M Buck Louis. Perfluoroalkyl Chemicals, Menstrual Cycle Length, and Fecundity: Findings from a Prospective Pregnancy Study.
Epidemiology (Cambridge, Mass.).
2017 01; 28(1):90-98. doi:
10.1097/ede.0000000000000552. [PMID: 27541842] - Wei Zhang, Nan Sheng, Minhui Wang, Hongxia Zhang, Jiayin Dai. Zebrafish reproductive toxicity induced by chronic perfluorononanoate exposure.
Aquatic toxicology (Amsterdam, Netherlands).
2016 Jun; 175(?):269-76. doi:
10.1016/j.aquatox.2016.04.005. [PMID: 27082981] - Sharon K Sagiv, Sheryl L Rifas-Shiman, Thomas F Webster, Ana Maria Mora, Maria H Harris, Antonia M Calafat, Xiaoyun Ye, Matthew W Gillman, Emily Oken. Sociodemographic and Perinatal Predictors of Early Pregnancy Per- and Polyfluoroalkyl Substance (PFAS) Concentrations.
Environmental science & technology.
2015 Oct; 49(19):11849-58. doi:
10.1021/acs.est.5b02489. [PMID: 26333069] - Maria Wielsøe, Manhai Long, Mandana Ghisari, Eva C Bonefeld-Jørgensen. Perfluoroalkylated substances (PFAS) affect oxidative stress biomarkers in vitro.
Chemosphere.
2015 Jun; 129(?):239-45. doi:
10.1016/j.chemosphere.2014.10.014. [PMID: 25455676] - Sabrina Tartu, Geir W Gabrielsen, Pierre Blévin, Hugh Ellis, Jan Ove Bustnes, Dorte Herzke, Olivier Chastel. Endocrine and fitness correlates of long-chain perfluorinated carboxylates exposure in Arctic breeding black-legged kittiwakes.
Environmental science & technology.
2014 Nov; 48(22):13504-10. doi:
10.1021/es503297n. [PMID: 25369114] - Camilla Bakken Aas, Eva Fuglei, Dorte Herzke, Nigel G Yoccoz, Heli Routti. Effect of body condition on tissue distribution of perfluoroalkyl substances (PFASs) in Arctic fox (Vulpes lagopus).
Environmental science & technology.
2014 Oct; 48(19):11654-61. doi:
10.1021/es503147n. [PMID: 25215880] - Glenys M Webster, Scott A Venners, Andre Mattman, Jonathan W Martin. Associations between perfluoroalkyl acids (PFASs) and maternal thyroid hormones in early pregnancy: a population-based cohort study.
Environmental research.
2014 Aug; 133(?):338-47. doi:
10.1016/j.envres.2014.06.012. [PMID: 25019470] - Yifeng Zhang, Weiwei Jiang, Shuhong Fang, Lingyan Zhu, Jimin Deng. Perfluoroalkyl acids and the isomers of perfluorooctanesulfonate and perfluorooctanoate in the sera of 50 new couples in Tianjin, China.
Environment international.
2014 Jul; 68(?):185-91. doi:
10.1016/j.envint.2014.03.022. [PMID: 24747327] - Jani Koponen, Panu Rantakokko, Riikka Airaksinen, Hannu Kiviranta. Determination of selected perfluorinated alkyl acids and persistent organic pollutants from a small volume human serum sample relevant for epidemiological studies.
Journal of chromatography. A.
2013 Sep; 1309(?):48-55. doi:
10.1016/j.chroma.2013.07.064. [PMID: 23972455] - Li-Li Wen, Lian-Yu Lin, Ta-Chen Su, Pau-Chung Chen, Chien-Yu Lin. Association between serum perfluorinated chemicals and thyroid function in U.S. adults: the National Health and Nutrition Examination Survey 2007-2010.
The Journal of clinical endocrinology and metabolism.
2013 Sep; 98(9):E1456-64. doi:
10.1210/jc.2013-1282. [PMID: 23864701] - Seung-Kyu Kim. Watershed-based riverine discharge loads and emission factor of perfluorinated surfactants in Korean peninsula.
Chemosphere.
2012 Nov; 89(8):995-1002. doi:
10.1016/j.chemosphere.2012.07.016. [PMID: 22863059] - Germaine M Buck Louis, C Matthew Peterson, Zhen Chen, Mary L Hediger, Mary S Croughan, Rajeshwari Sundaram, Joseph B Stanford, Victor Y Fujimoto, Michael W Varner, Linda C Giudice, Anne Kennedy, Liping Sun, Qian Wu, Kurunthachalam Kannan. Perfluorochemicals and endometriosis: the ENDO study.
Epidemiology (Cambridge, Mass.).
2012 Nov; 23(6):799-805. doi:
10.1097/ede.0b013e31826cc0cf. [PMID: 22992575] - G Toft, B A G Jönsson, C H Lindh, A Giwercman, M Spano, D Heederik, V Lenters, R Vermeulen, L Rylander, H S Pedersen, J K Ludwicki, V Zviezdai, J P Bonde. Exposure to perfluorinated compounds and human semen quality in Arctic and European populations.
Human reproduction (Oxford, England).
2012 Aug; 27(8):2532-40. doi:
10.1093/humrep/des185. [PMID: 22647447] - Geary W Olsen, Cleston C Lange, Mark E Ellefson, David C Mair, Timothy R Church, Corinne L Goldberg, Ross M Herron, Zahra Medhdizadehkashi, John B Nobiletti, Jorge A Rios, William K Reagen, Larry R Zobel. Temporal trends of perfluoroalkyl concentrations in American Red Cross adult blood donors, 2000-2010.
Environmental science & technology.
2012 Jun; 46(11):6330-8. doi:
10.1021/es300604p. [PMID: 22554481] - Tomohiko Nakagawa, Doni Hikmat Ramdhan, Naoki Tanaka, Hisao Naito, Hazuki Tamada, Yuki Ito, Yufei Li, Yumi Hayashi, Nozomi Yamagishi, Yukie Yanagiba, Toshifumi Aoyama, Frank J Gonzalez, Tamie Nakajima. Modulation of ammonium perfluorooctanoate-induced hepatic damage by genetically different PPARα in mice.
Archives of toxicology.
2012 Jan; 86(1):63-74. doi:
10.1007/s00204-011-0704-3. [PMID: 21499893] - Kayoko Kato, Lee-Yang Wong, Lily T Jia, Zsuzsanna Kuklenyik, Antonia M Calafat. Trends in exposure to polyfluoroalkyl chemicals in the U.S. Population: 1999-2008.
Environmental science & technology.
2011 Oct; 45(19):8037-45. doi:
10.1021/es1043613. [PMID: 21469664] - Yasuyuki Zushi, Feng Ye, Mamoru Motegi, Kiyoshi Nojiri, Shigeo Hosono, Toshinari Suzuki, Yuki Kosugi, Kumiko Yaguchi, Shigeki Masunaga. Spatially detailed survey on pollution by multiple perfluorinated compounds in the Tokyo Bay basin of Japan.
Environmental science & technology.
2011 Apr; 45(7):2887-93. doi:
10.1021/es103917r. [PMID: 21384896] - ChuanFang Jin, YingHua Sun, Ahmed Islam, Yong Qian, Alan Ducatman. Perfluoroalkyl acids including perfluorooctane sulfonate and perfluorohexane sulfonate in firefighters.
Journal of occupational and environmental medicine.
2011 Mar; 53(3):324-8. doi:
10.1097/jom.0b013e31820d1314. [PMID: 21346631] - Yang Liu, Jianshe Wang, Xuemei Fang, Hongxia Zhang, Jiayin Dai. The thyroid-disrupting effects of long-term perfluorononanoate exposure on zebrafish (Danio rerio).
Ecotoxicology (London, England).
2011 Jan; 20(1):47-55. doi:
10.1007/s10646-010-0555-3. [PMID: 20941541] - Yi M Weaver, David J Ehresman, John L Butenhoff, Bruno Hagenbuch. Roles of rat renal organic anion transporters in transporting perfluorinated carboxylates with different chain lengths.
Toxicological sciences : an official journal of the Society of Toxicology.
2010 Feb; 113(2):305-14. doi:
10.1093/toxsci/kfp275. [PMID: 19915082] - C J Sakr, J M Symons, K H Kreckmann, R C Leonard. Ischaemic heart disease mortality study among workers with occupational exposure to ammonium perfluorooctanoate.
Occupational and environmental medicine.
2009 Oct; 66(10):699-703. doi:
10.1136/oem.2008.041582. [PMID: 19553230] - Ondine S von Ehrenstein, Suzanne E Fenton, Kayoko Kato, Zsuzsanna Kuklenyik, Antonia M Calafat, Erin P Hines. Polyfluoroalkyl chemicals in the serum and milk of breastfeeding women.
Reproductive toxicology (Elmsford, N.Y.).
2009 Jun; 27(3-4):239-245. doi:
10.1016/j.reprotox.2009.03.001. [PMID: 19429402] - Chien-Yu Lin, Pau-Chung Chen, Yu-Chuan Lin, Lian-Yu Lin. Association among serum perfluoroalkyl chemicals, glucose homeostasis, and metabolic syndrome in adolescents and adults.
Diabetes care.
2009 Apr; 32(4):702-7. doi:
10.2337/dc08-1816. [PMID: 19114613] - Charlotta Rylander, Magritt Brustad, Helena Falk, Torkjel M Sandanger. Dietary predictors and plasma concentrations of perfluorinated compounds in a coastal population from northern Norway.
Journal of environmental and public health.
2009; 2009(?):268219. doi:
10.1155/2009/268219. [PMID: 20111729] - Kaberi P Das, Brian E Grey, Robert D Zehr, Carmen R Wood, John L Butenhoff, Shu-Ching Chang, David J Ehresman, Yu-Mei Tan, Christopher Lau. Effects of perfluorobutyrate exposure during pregnancy in the mouse.
Toxicological sciences : an official journal of the Society of Toxicology.
2008 Sep; 105(1):173-81. doi:
10.1093/toxsci/kfn099. [PMID: 18511431] - Carine J Sakr, Kim H Kreckmann, John W Green, Peter J Gillies, Julia L Reynolds, Robin C Leonard. Cross-sectional study of lipids and liver enzymes related to a serum biomarker of exposure (ammonium perfluorooctanoate or APFO) as part of a general health survey in a cohort of occupationally exposed workers.
Journal of occupational and environmental medicine.
2007 Oct; 49(10):1086-96. doi:
10.1097/jom.0b013e318156eca3. [PMID: 18000414] - W Matthew Henderson, Mary Alice Smith. Perfluorooctanoic acid and perfluorononanoic acid in fetal and neonatal mice following in utero exposure to 8-2 fluorotelomer alcohol.
Toxicological sciences : an official journal of the Society of Toxicology.
2007 Feb; 95(2):452-61. doi:
10.1093/toxsci/kfl162. [PMID: 17093205] - N Kudo, E Suzuki, M Katakura, K Ohmori, R Noshiro, Y Kawashima. Comparison of the elimination between perfluorinated fatty acids with different carbon chain length in rats.
Chemico-biological interactions.
2001 Apr; 134(2):203-16. doi:
10.1016/s0009-2797(01)00155-7. [PMID: 11311214] - G C Varnam, M K Jeacock, D A Shepherd. Activities of ketone body utilising enzymes in tissues of fed and fasted sheep.
Research in veterinary science.
1978 Jan; 24(1):124-5. doi:
10.1016/s0034-5288(18)33113-8. [PMID: 24243]