CD437 (BioDeep_00001875224)
代谢物信息卡片
化学式: C27H26O3 (398.1881846)
中文名称: CD 437
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1C2CC3CC1CC(C2)(C3)C4=C(C=CC(=C4)C5=CC6=C(C=C5)C=C(C=C6)C(=O)O)O
InChI: InChI=1S/C27H26O3/c28-25-6-5-22(20-1-2-21-11-23(26(29)30)4-3-19(21)10-20)12-24(25)27-13-16-7-17(14-27)9-18(8-16)15-27/h1-6,10-12,16-18,28H,7-9,13-15H2,(H,29,30)
描述信息
D020011 - Protective Agents > D000975 - Antioxidants > D002338 - Carotenoids
D000970 - Antineoplastic Agents
同义名列表
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Ana V Cheng, Wooseong Kim, Iliana E Escobar, Eleftherios Mylonakis, William M Wuest. Structure-Activity Relationship and Anticancer Profile of Second-Generation Anti-MRSA Synthetic Retinoids.
ACS medicinal chemistry letters.
2020 Mar; 11(3):393-397. doi:
10.1021/acsmedchemlett.9b00159. [PMID: 32184975] - Wooseong Kim, Wenpeng Zhu, Gabriel Lambert Hendricks, Daria Van Tyne, Andrew D Steele, Colleen E Keohane, Nico Fricke, Annie L Conery, Steven Shen, Wen Pan, Kiho Lee, Rajmohan Rajamuthiah, Beth Burgwyn Fuchs, Petia M Vlahovska, William M Wuest, Michael S Gilmore, Huajian Gao, Frederick M Ausubel, Eleftherios Mylonakis. A new class of synthetic retinoid antibiotics effective against bacterial persisters.
Nature.
2018 04; 556(7699):103-107. doi:
10.1038/nature26157. [PMID: 29590091] - Gabriella Garruti, Helen H Wang, Leonilde Bonfrate, Ornella de Bari, David Q-H Wang, Piero Portincasa. A pleiotropic role for the orphan nuclear receptor small heterodimer partner in lipid homeostasis and metabolic pathways.
Journal of lipids.
2012; 2012(?):304292. doi:
10.1155/2012/304292. [PMID: 22577560] - Arun K Rishi, Liyue Zhang, Madanamohan Boyanapalli, Anil Wali, Ramzi M Mohammad, Yingjie Yu, Joseph A Fontana, James S Hatfield, Marcia I Dawson, Adhip P N Majumdar, Uwe Reichert. Identification and characterization of a cell cycle and apoptosis regulatory protein-1 as a novel mediator of apoptosis signaling by retinoid CD437.
The Journal of biological chemistry.
2003 Aug; 278(35):33422-35. doi:
10.1074/jbc.m303173200. [PMID: 12816952] - A S Belzacq, C El Hamel, H L Vieira, I Cohen, D Haouzi, D Métivier, P Marchetti, C Brenner, G Kroemer. Adenine nucleotide translocator mediates the mitochondrial membrane permeabilization induced by lonidamine, arsenite and CD437.
Oncogene.
2001 Nov; 20(52):7579-87. doi:
10.1038/sj.onc.1204953. [PMID: 11753636] - H M Arafa, M M Elmazar, F M Hamada, U Reichert, B Shroot, H Nau. Selective agonists of retinoic acid receptors: comparative toxicokinetics and embryonic exposure.
Archives of toxicology.
2000 Jan; 73(10-11):547-56. doi:
10.1007/s002040050007. [PMID: 10663386] - M Sakaue, H Adachi, A M Jetten. Post-transcriptional regulation of MyD118 and GADD45 in human lung carcinoma cells during 6-[3-(1-adamantyl)-4-hydroxyphenyl]-2- naphthalene carboxylic acid-induced apoptosis.
Molecular pharmacology.
1999 Apr; 55(4):668-76. doi:
. [PMID: 10101024] - C P Zou, W K Hong, R Lotan. Expression of retinoic acid receptor beta is associated with inhibition of keratinization in human head and neck squamous carcinoma cells.
Differentiation; research in biological diversity.
1999 Jan; 64(2):123-32. doi:
10.1046/j.1432-0436.1999.6420123.x. [PMID: 10234809] - H M Arafa, F M Hamada, M M Elmazar, H Nau. Fully automated determination of selective retinoic acid receptor ligands in mouse plasma and tissue by reversed-phase liquid chromatography coupled on-line with solid-phase extraction.
Journal of chromatography. A.
1996 Apr; 729(1-2):125-36. doi:
10.1016/0021-9673(95)00980-9. [PMID: 9004933]