N-(2,6-dimethylphenyl)piperidine-2-carboxamide (BioDeep_00001875160)

   


代谢物信息卡片


N-(2,6-dimethylphenyl)piperidine-2-carboxamide

化学式: C14H20N2O (232.157555)
中文名称: N-(2,6-二甲基苯基)哌啶-2-甲酰胺
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC1=C(C(=CC=C1)C)NC(=O)C2CCCCN2
InChI: InChI=1S/C14H20N2O/c1-10-6-5-7-11(2)13(10)16-14(17)12-8-3-4-9-15-12/h5-7,12,15H,3-4,8-9H2,1-2H3,(H,16,17)



数据库引用编号

3 个数据库交叉引用编号

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相关代谢途径

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代谢反应

0 个相关的代谢反应过程信息。

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INOH(0)

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0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • L Aarons, B Sadler, M Pitsiu, J Sjövall, J Henriksson, V Molnár. Population pharmacokinetic analysis of ropivacaine and its metabolite 2',6'-pipecoloxylidide from pooled data in neonates, infants, and children. British journal of anaesthesia. 2011 Sep; 107(3):409-24. doi: 10.1093/bja/aer154. [PMID: 21693469]
  • P J Pere, A Ekstrand, M Salonen, E Honkanen, J Sjövall, J Henriksson, P H Rosenberg. Pharmacokinetics of ropivacaine in patients with chronic renal failure. British journal of anaesthesia. 2011 Apr; 106(4):512-21. doi: 10.1093/bja/aer002. [PMID: 21307007]
  • Robin Ledger. Nonaromatic hydroxylation of bupivacaine during continuous epidural infusion in man. Journal of biochemical and biophysical methods. 2003 Aug; 57(2):105-14. doi: 10.1016/s0165-022x(03)00099-x. [PMID: 12915004]
  • Ryan M Krisko, Mark A Schieferecke, Todd D Williams, Craig E Lunte. Determination of bupivacaine and metabolites in rat urine using capillary electrophoresis with mass spectrometric detection. Electrophoresis. 2003 Jul; 24(14):2340-7. doi: 10.1002/elps.200305469. [PMID: 12874869]
  • Pertti Pere, Merja Salonen, Mika Jokinen, Per H Rosenberg, Pertti J Neuvonen, Juhani Haasio. Pharmacokinetics of ropivacaine in uremic and nonuremic patients after axillary brachial plexus block. Anesthesia and analgesia. 2003 Feb; 96(2):563-9, table of contents. doi: 10.1097/00000539-200302000-00048. [PMID: 12538213]
  • Mika J Jokinen, Klaus T Olkkola, Jouni Ahonen, Pertti J Neuvonen. Effect of ciprofloxacin on the pharmacokinetics of ropivacaine. European journal of clinical pharmacology. 2003 Feb; 58(10):653-7. doi: 10.1007/s00228-002-0540-8. [PMID: 12610740]
  • S Ganapathy, R A Wasserman, J T Watson, J Bennett, K P Armstrong, C A Stockall, D G Chess, C MacDonald. Modified continuous femoral three-in-one block for postoperative pain after total knee arthroplasty. Anesthesia and analgesia. 1999 Nov; 89(5):1197-202. doi: . [PMID: 10553834]
  • D Ortega, X Viviand, A M Lorec, M Gamerre, C Martin, B Bruguerolle. Excretion of lidocaine and bupivacaine in breast milk following epidural anesthesia for cesarean delivery. Acta anaesthesiologica Scandinavica. 1999 Apr; 43(4):394-7. doi: 10.1034/j.1399-6576.1999.430405.x. [PMID: 10225071]
  • S Reif, P Le Corre, G Dollo, F Chevanne, R Le Verge. High-performance liquid chromatographic determination of ropivacaine, 3-hydroxy-ropivacaine, 4-hydroxy-ropivacaine and 2',6'-pipecoloxylidide in plasma. Journal of chromatography. B, Biomedical sciences and applications. 1998 Nov; 719(1-2):239-44. doi: 10.1016/s0378-4347(98)00442-3. [PMID: 9869387]
  • M A Schieferecke, K J McLaughlin, A A Faibushevich, C E Lunte. Determination of bupivacaine and three of its metabolites in rat urine by capillary electrophoresis. Electrophoresis. 1998 Nov; 19(16-17):2997-3002. doi: 10.1002/elps.1150191633. [PMID: 9870402]
  • L Attolini, M Gantenbein, B Bruguerolle. Effects of tobacco smoke exposure on the kinetics of bupivacaine in mice. Life sciences. 1997; 60(10):725-34. doi: 10.1016/s0024-3205(97)00003-9. [PMID: 9064477]
  • B Bruguerolle, L Attolini, A M Lorec, M Gantenbein. Kinetics of bupivacaine after clonidine pretreatment in mice. Canadian journal of anaesthesia = Journal canadien d'anesthesie. 1995 May; 42(5 Pt 1):434-7. doi: 10.1007/bf03015492. [PMID: 7614654]
  • T Arvidsson, H F Bruce, M M Halldin. Lack of metabolic racemisation of ropivacaine, determined by liquid chromatography using a chiral AGP column. Chirality. 1995; 7(4):272-7. doi: 10.1002/chir.530070414. [PMID: 7640170]
  • E Giaufré, B Bruguerolle, C Rastello, M Coquet, A M Lorec. New regimen for interpleural block in children. Paediatric anaesthesia. 1995; 5(2):125-8. doi: 10.1111/j.1460-9592.1995.tb00259.x. [PMID: 7489422]
  • A M Lorec, B Bruguerolle, L Attolini, X Roucoules. Rapid simultaneous determination of lidocaine, bupivacaine, and their two main metabolites using capillary gas-liquid chromatography with nitrogen phosphorus detector. Therapeutic drug monitoring. 1994 Dec; 16(6):592-5. doi: 10.1097/00007691-199412000-00010. [PMID: 7878699]
  • R N Gupta, A Dauphin. Column liquid chromatographic determination of bupivacaine in human serum using solid-phase extraction. Journal of chromatography. B, Biomedical applications. 1994 Aug; 658(1):113-9. doi: 10.1016/0378-4347(94)00214-2. [PMID: 7952111]
  • B Bruguerolle, L Attolini, X Roucoules, A M Lorec. Cigarette smoke increases bupivacaine metabolism in rats. Canadian journal of anaesthesia = Journal canadien d'anesthesie. 1994 Aug; 41(8):733-7. doi: 10.1007/bf03015630. [PMID: 7923523]
  • H Kastrissios, M F Hung, E J Triggs. High-performance liquid chromatographic method for the quantitation of bupivacaine, 2,6-pipecoloxylidide and 4'-hydroxybupivacaine in plasma and urine. Journal of chromatography. 1992 May; 577(1):103-7. doi: 10.1016/0378-4347(92)80603-n. [PMID: 1400728]
  • P Pere, M Tuominen, P H Rosenberg. Cumulation of bupivacaine, desbutylbupivacaine and 4-hydroxybupivacaine during and after continuous interscalene brachial plexus block. Acta anaesthesiologica Scandinavica. 1991 Oct; 35(7):647-50. doi: 10.1111/j.1399-6576.1991.tb03365.x. [PMID: 1785246]
  • P H Rosenberg, P Pere, R Hekali, M Tuominen. Plasma concentrations of bupivacaine and two of its metabolites during continuous interscalene brachial plexus block. British journal of anaesthesia. 1991 Jan; 66(1):25-30. doi: 10.1093/bja/66.1.25. [PMID: 1997055]
  • K Pihlajamäki, J Kanto, R Lindberg, M Karanko, P Kiilholma. Extradural administration of bupivacaine: pharmacokinetics and metabolism in pregnant and non-pregnant women. British journal of anaesthesia. 1990 May; 64(5):556-62. doi: 10.1093/bja/64.5.556. [PMID: 2354094]
  • J A Odoom, A Sturk, P W Dokter, J G Bovill, J W ten Cate, J Oosting. The effects of bupivacaine and pipecoloxylidide on platelet function in vitro. Acta anaesthesiologica Scandinavica. 1989 Jul; 33(5):385-8. doi: 10.1111/j.1399-6576.1989.tb02928.x. [PMID: 2529732]
  • R L Lindberg, J H Kanto, K K Pihlajamäki. Simultaneous determination of bupivacaine and its two metabolites, desbutyl- and 4'-hydroxybupivacaine, in human serum and urine. Journal of chromatography. 1986 Dec; 383(2):357-64. doi: 10.1016/s0378-4347(00)83481-7. [PMID: 3558565]
  • P M Kuhnert, B R Kuhnert, J M Stitts, T L Gross. The use of a selected ion monitoring technique to study the disposition of bupivacaine in mother, fetus, and neonate following epidural anesthesia for cesarean section. Anesthesiology. 1981 Dec; 55(6):611-7. doi: 10.1097/00000542-198155060-00001. [PMID: 7305051]
  • L J Lesko, J Ericson, G Ostheimer, A Marion. Simultaneous determination of bupivacaine and 2,6-pipecoloxylidide in serum by gas-liquid chromatography. Journal of chromatography. 1980 May; 182(2):226-231. doi: 10.1016/s0378-4347(00)81627-8. [PMID: 7380915]
  • E H Kass. Bacterial antigen in the kidney. The New England journal of medicine. 1969 Dec; 281(25):1420-1. doi: 10.1056/nejm196912182812510. [PMID: 5355457]