1,2-benzoxazole (BioDeep_00001875137)
代谢物信息卡片
化学式: C7H5NO (119.03711200000001)
中文名称: 1,2-苯基异恶唑
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1=CC=C2C(=C1)C=NO2
InChI: InChI=1S/C7H5NO/c1-2-4-7-6(3-1)5-8-9-7/h1-5H
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- R M Abou El-Magd, H K Park, T Kawazoe, S Iwana, K Ono, S P Chung, M Miyano, K Yorita, T Sakai, K Fukui. The effect of risperidone on D-amino acid oxidase activity as a hypothesis for a novel mechanism of action in the treatment of schizophrenia.
Journal of psychopharmacology (Oxford, England).
2010 Jul; 24(7):1055-67. doi:
10.1177/0269881109102644
. [PMID: 19329549] - Bo-Liang Deng, Yujie Zhao, Tracy L Hartman, Karen Watson, Robert W Buckheit, Christophe Pannecouque, Erik De Clercq, Mark Cushman. Synthesis of alkenyldiarylmethanes (ADAMs) containing benzo[d]isoxazole and oxazolidin-2-one rings, a new series of potent non-nucleoside HIV-1 reverse transcriptase inhibitors.
European journal of medicinal chemistry.
2009 Mar; 44(3):1210-4. doi:
10.1016/j.ejmech.2008.09.013
. [PMID: 18952324] - Marc Vermeir, Ineke Naessens, Bart Remmerie, Geert Mannens, Jan Hendrickx, Patrick Sterkens, Krishna Talluri, Sandra Boom, Marielle Eerdekens, Nancy van Osselaer, Adriaan Cleton. Absorption, metabolism, and excretion of paliperidone, a new monoaminergic antagonist, in humans.
Drug metabolism and disposition: the biological fate of chemicals.
2008 Apr; 36(4):769-79. doi:
10.1124/dmd.107.018275
. [PMID: 18227146] - Donglu Zhang, Nirmala Raghavan, Shiang-Yuan Chen, Haiying Zhang, Mimi Quan, Lloyd Lecureux, Laura M Patrone, Patrick Y S Lam, Samuel J Bonacorsi, Robert M Knabb, Gary L Skiles, Kan He. Reductive isoxazole ring opening of the anticoagulant razaxaban is the major metabolic clearance pathway in rats and dogs.
Drug metabolism and disposition: the biological fate of chemicals.
2008 Feb; 36(2):303-15. doi:
10.1124/dmd.107.018416
. [PMID: 17984286] - Lawrence James Albers, Alessandro Musenga, Maria Augusta Raggi. Iloperidone: a new benzisoxazole atypical antipsychotic drug. Is it novel enough to impact the crowded atypical antipsychotic market?.
Expert opinion on investigational drugs.
2008 Jan; 17(1):61-75. doi:
10.1517/13543784.17.1.61
. [PMID: 18095919] - Philip G Janicak, Elizabeth A Winans. Paliperidone ER: a review of the clinical trial data.
Neuropsychiatric disease and treatment.
2007 Dec; 3(6):869-97. doi:
10.2147/ndt.s1365
. [PMID: 19300622] - Bo-Liang Deng, Matthew D Cullen, Zhigang Zhou, Tracy L Hartman, Robert W Buckheit, Christophe Pannecouque, Erik De Clercq, Phillip E Fanwick, Mark Cushman. Synthesis and anti-HIV activity of new alkenyldiarylmethane (ADAM) non-nucleoside reverse transcriptase inhibitors (NNRTIs) incorporating benzoxazolone and benzisoxazole rings.
Bioorganic & medicinal chemistry.
2006 Apr; 14(7):2366-74. doi:
10.1016/j.bmc.2005.11.014
. [PMID: 16321539] - Toru Sanai, Rei Matsui, Tadashi Hirano, Shinichi Torichigai, Hideki Yotsueda, Harumichi Higashi, Hideki Hirakata, Mitsuo Iida. Successful treatment of six patients with neuroleptic malignant syndrome associated with myoglobulinemic acute renal failure.
Renal failure.
2006; 28(1):51-5. doi:
10.1080/08860220500461252
. [PMID: 16526319] - David E Moody, John D Laycock, Wei Huang, Rodger L Foltz. A high-performance liquid chromatographic-atmospheric pressure chemical ionization-tandem mass spectrometric method for determination of risperidone and 9-hydroxyrisperidone in human plasma.
Journal of analytical toxicology.
2004 Sep; 28(6):494-7. doi:
10.1093/jat/28.6.494
. [PMID: 15516302] - X C Liu, P Lemma-Gray. Biocatalysis of isomerization of 1,2-benzisoxazole by bovine serum albumin in an organic solvent.
Biotechnology and bioengineering.
2001 Sep; 74(6):524-7. doi:
10.1002/bit.1144
. [PMID: 11494220]