(+/-)-Dihydromethysticin (BioDeep_00001874825)

   


代谢物信息卡片


2-[2-(1,3-benzodioxol-5-yl)ethyl]-4-methoxy-2,3-dihydropyran-6-one

化学式: C15H16O5 (276.0997686)
中文名称: 二氢甲基葡萄球菌素
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: COC1=CC(=O)OC(C1)CCC2=CC3=C(C=C2)OCO3
InChI: InChI=1S/C15H16O5/c1-17-12-7-11(20-15(16)8-12)4-2-10-3-5-13-14(6-10)19-9-18-13/h3,5-6,8,11H,2,4,7,9H2,1H3

描述信息

同义名列表

2 个代谢物同义名

2-[2-(1,3-benzodioxol-5-yl)ethyl]-4-methoxy-2,3-dihydropyran-6-one; (+/-)-Dihydromethysticin



数据库引用编号

5 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Rolf Teschke, Vincent Lebot. Proposal for a kava quality standardization code. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2011 Oct; 49(10):2503-16. doi: 10.1016/j.fct.2011.06.075. [PMID: 21756963]
  • Paul Whittaker, Jane J Clarke, Richard H C San, Joseph M Betz, Harold E Seifried, Lowri S de Jager, Virginia C Dunkel. Evaluation of commercial kava extracts and kavalactone standards for mutagenicity and toxicity using the mammalian cell gene mutation assay in L5178Y mouse lymphoma cells. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2008 Jan; 46(1):168-74. doi: 10.1016/j.fct.2007.07.013. [PMID: 17822821]
  • T D Xuan, A A Elzaawely, M Fukuta, S Tawata. Herbicidal and Fungicidal Activities of Lactones in Kava (Piper methysticum). Journal of agricultural and food chemistry. 2006 Feb; 54(3):720-5. doi: 10.1021/jf0519461. [PMID: 16448174]
  • Emma Warburton, Tony Bristow. Fourier transform ion cyclotron resonance mass spectrometry for the characterisation of kavalactones in the kava plant: elemental formulae confirmation by dual spray accurate mass measurement and structural confirmation by infrared multiphoton dissociation and sustained off-resonance irradiation collision induced dissociation. European journal of mass spectrometry (Chichester, England). 2006; 12(4):223-33. doi: 10.1255/ejms.808. [PMID: 17057279]
  • Johanna Weiss, Alexandra Sauer, Andreas Frank, Matthias Unger. Extracts and kavalactones of Piper methysticum G. Forst (kava-kava) inhibit P-glycoprotein in vitro. Drug metabolism and disposition: the biological fate of chemicals. 2005 Nov; 33(11):1580-3. doi: 10.1124/dmd.105.005892. [PMID: 16051732]
  • James M Mathews, Amy S Etheridge, John L Valentine, Sherry R Black, Donna P Coleman, Purvi Patel, James So, Leo T Burka. Pharmacokinetics and disposition of the kavalactone kawain: interaction with kava extract and kavalactones in vivo and in vitro. Drug metabolism and disposition: the biological fate of chemicals. 2005 Oct; 33(10):1555-63. doi: 10.1124/dmd.105.004317. [PMID: 16033948]
  • Yuzhong Ma, Karuna Sachdeva, Jirong Liu, Michael Ford, Dongfang Yang, Ikhlas A Khan, Clinton O Chichester, Bingfang Yan. Desmethoxyyangonin and dihydromethysticin are two major pharmacological kavalactones with marked activity on the induction of CYP3A23. Drug metabolism and disposition: the biological fate of chemicals. 2004 Nov; 32(11):1317-24. doi: 10.1124/dmd.104.000786. [PMID: 15282211]
  • L S de Jager, G A Perfetti, G W Diachenko. LC-UV and LC-MS analysis of food and drink products containing kava. Food additives and contaminants. 2004 Oct; 21(10):921-34. doi: 10.1080/02652030400010454. [PMID: 15712517]
  • James M Mathews, Amy S Etheridge, Sherry R Black. Inhibition of human cytochrome P450 activities by kava extract and kavalactones. Drug metabolism and disposition: the biological fate of chemicals. 2002 Nov; 30(11):1153-7. doi: 10.1124/dmd.30.11.1153. [PMID: 12386118]
  • L Zou, M R Harkey, G L Henderson. Effects of herbal components on cDNA-expressed cytochrome P450 enzyme catalytic activity. Life sciences. 2002 Aug; 71(13):1579-89. doi: 10.1016/s0024-3205(02)01913-6. [PMID: 12127912]
  • D Wu, L Yu, M G Nair, D L DeWitt, R S Ramsewak. Cyclooxygenase enzyme inhibitory compounds with antioxidant activities from Piper methysticum (kava kava) roots. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2002 Jan; 9(1):41-7. doi: 10.1078/0944-7113-00068. [PMID: 11924763]