5,11-Dimethyl-6H-pyrido[4,3-b]carbazol-9-ol (BioDeep_00001874758)

   

natural product


代谢物信息卡片


5,11-Dimethyl-6H-pyrido[4,3-b]carbazol-9-ol

化学式: C17H14N2O (262.1106074)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC1=C2C=CN=CC2=C(C3=C1NC4=C3C=C(C=C4)O)C
InChI: InChI=1S/C17H14N2O/c1-9-14-8-18-6-5-12(14)10(2)17-16(9)13-7-11(20)3-4-15(13)19-17/h3-8,19-20H,1-2H3

描述信息

D000970 - Antineoplastic Agents > D000972 - Antineoplastic Agents, Phytogenic > D004611 - Ellipticines
D009676 - Noxae > D000963 - Antimetabolites

同义名列表

1 个代谢物同义名

5,11-Dimethyl-6H-pyrido[4,3-b]carbazol-9-ol



数据库引用编号

5 个数据库交叉引用编号

分类词条

相关代谢途径

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代谢反应

0 个相关的代谢反应过程信息。

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9 个相关的物种来源信息

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  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

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文献列表

  • Andreia Montoia, Luiz F Rocha E Silva, Zelina E Torres, David S Costa, Marycleuma C Henrique, Emerson S Lima, Marne C Vasconcellos, Rita C Z Souza, Monica R F Costa, Andriy Grafov, Iryna Grafova, Marcos N Eberlin, Wanderli P Tadei, Rodrigo C N Amorim, Adrian M Pohlit. Antiplasmodial activity of synthetic ellipticine derivatives and an isolated analog. Bioorganic & medicinal chemistry letters. 2014 Jun; 24(12):2631-4. doi: 10.1016/j.bmcl.2014.04.070. [PMID: 24813729]
  • P Rigaudy, J Y Charcosset, C Garbay-Jaureguiberry, A Jacquemin-Sablon, B P Roques. Attempts to target antitumor drugs toward opioid receptor-rich mouse tumor cells with enkephalin-ellipticinium conjugates. Cancer research. 1989 Apr; 49(7):1836-42. doi: . [PMID: 2538235]
  • L Lempereur, A M Sautereau, J F Tocanne, G Laneelle. Ellipticine derivatives interacting with model membranes. Influence of quaternarization of nitrogen-2. Biochemical pharmacology. 1984 Aug; 33(15):2499-503. doi: 10.1016/0006-2952(84)90724-x. [PMID: 6466364]
  • I Brandt, J A Gustafsson, J Rafter. Distribution of the carcinogenic tryptophan pyrolysis product Trp-P-1 in control, 9-hydroxyellipticine and beta-naphthoflavone pretreated mice. Carcinogenesis. 1983 Oct; 4(10):1291-6. doi: 10.1093/carcin/4.10.1291. [PMID: 6616757]
  • M W Teunissen, R P Joeres, N P Vermeulen, D D Breimer. Influence of 9-hydroxyellipticine and 3-methylcholanthrene treatment on antipyrine metabolite formation in rats in vivo. Xenobiotica; the fate of foreign compounds in biological systems. 1983 Apr; 13(4):223-31. doi: 10.3109/00498258309052258. [PMID: 6624137]
  • G Bykadi, K P Flora, J C Cradock, G K Poochikian. Determination of ellipticine in biological samples by high-performance liquid chromatography. Journal of chromatography. 1982 Aug; 231(1):137-44. doi: 10.1016/s0378-4347(00)80517-4. [PMID: 7119056]
  • C Auclair, C Paoletti. Bioactivation of the antitumor drugs 9-hydroxyellipticine and derivatives by a peroxidase-hydrogen peroxide system. Journal of medicinal chemistry. 1981 Mar; 24(3):289-95. doi: 10.1021/jm00135a010. [PMID: 7265115]
  • N Van-Bac, C Moisand, A Gouyette, G Muzard, N Dat-Xuong, J B Le Pecq, C Paoletti. Metabolism and disposition studies of 9-hydroxyellipticine and 2-methyl-9-hydroxyellipticinium acetate in animals. Cancer treatment reports. 1980 Aug; 64(8-9):879-87. doi: NULL. [PMID: 7448826]