Acetyldeoxynivalenol (BioDeep_00001874517)
代谢物信息卡片
Acetyldeoxynivalenol
化学式: C17H22O7 (338.1365462)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC1=CC2C(C(C1=O)O)(C3(CC(C(C34CO4)O2)OC(=O)C)C)CO
InChI: InChI=1S/C17H22O7/c1-8-4-11-16(6-18,13(21)12(8)20)15(3)5-10(23-9(2)19)14(24-11)17(15)7-22-17/h4,10-11,13-14,18,21H,5-7H2,1-3H3
描述信息
D009676 - Noxae > D011042 - Poisons > D014255 - Trichothecenes
D009676 - Noxae > D011042 - Poisons > D009183 - Mycotoxins
同义名列表
1 个代谢物同义名
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
- 5518 - Fusarium graminearum: 10.1007/BF00597600
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Hai Jia, Tongkun Zhang, Ning Liu, Xuemeng Si, Jun Bai, Ying Yang, Zhaohui Chen, Zhenlong Wu. 4-Phenylbutyric acid alleviates 3-acetyldeoxynivalenol-induced immune cells response by inhibiting endoplasmic reticulum stress in mouse spleen.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
2022 Jun; 164(?):113002. doi:
10.1016/j.fct.2022.113002. [PMID: 35413383] - Beatriz Arce-López, Lydia Alvarez-Erviti, Barbara De Santis, María Izco, Silvia López-Calvo, Maria Eugenia Marzo-Sola, Francesca Debegnach, Elena Lizarraga, Adela López de Cerain, Elena González-Peñas, Ariane Vettorazzi. Biomonitoring of Mycotoxins in Plasma of Patients with Alzheimer's and Parkinson's Disease.
Toxins.
2021 07; 13(7):. doi:
10.3390/toxins13070477. [PMID: 34357949] - Jing Jin, Albertus Spenkelink, Karsten Beekmann, Marta Baccaro, Fuguo Xing, Ivonne M C M Rietjens. Species Differences in in vitro and Estimated in vivo Kinetics for Intestinal Microbiota Mediated Metabolism of Acetyl-deoxynivalenols.
Molecular nutrition & food research.
2021 05; 65(9):e2001085. doi:
10.1002/mnfr.202001085. [PMID: 33635583] - Jin-Quan Huang, Jia-Ling Lin, Xiao-Xiang Guo, Xiu Tian, Ye Tian, Xiao-Xia Shangguan, Ling-Jian Wang, Xin Fang, Xiao-Ya Chen. RES transformation for biosynthesis and detoxification.
Science China. Life sciences.
2020 Sep; 63(9):1297-1302. doi:
10.1007/s11427-020-1729-5. [PMID: 32519031] - Chen Huang, Manu P Gangola, Seedhabadee Ganeshan, Pierre Hucl, H Randy Kutcher, Ravindra N Chibbar. Spike culture derived wheat (Triticum aestivum L.) variants exhibit improved resistance to multiple chemotypes of Fusarium graminearum.
PloS one.
2019; 14(12):e0226695. doi:
10.1371/journal.pone.0226695. [PMID: 31856194] - El Hassan Ajandouz, Stéphane Berdah, Vincent Moutardier, Thierry Bege, David Jérémie Birnbaum, Josette Perrier, Eric Di Pasquale, Marc Maresca. Hydrolytic Fate of 3/15-Acetyldeoxynivalenol in Humans: Specific Deacetylation by the Small Intestine and Liver Revealed Using in Vitro and ex Vivo Approaches.
Toxins.
2016 07; 8(8):. doi:
10.3390/toxins8080232. [PMID: 27483321] - Jennifer Duringer, Eric Fombonne, Morrie Craig. No Association between Mycotoxin Exposure and Autism: A Pilot Case-Control Study in School-Aged Children.
Toxins.
2016 07; 8(7):. doi:
10.3390/toxins8070224. [PMID: 27447670] - Nathan Broekaert, Mathias Devreese, Thomas De Mil, Sophie Fraeyman, Gunther Antonissen, Siegrid De Baere, Patrick De Backer, An Vermeulen, Siska Croubels. Oral Bioavailability, Hydrolysis, and Comparative Toxicokinetics of 3-Acetyldeoxynivalenol and 15-Acetyldeoxynivalenol in Broiler Chickens and Pigs.
Journal of agricultural and food chemistry.
2015 Oct; 63(39):8734-42. doi:
10.1021/acs.jafc.5b03270. [PMID: 26343882] - Paulo R Kuhnem, Pierri Spolti, Emerson M Del Ponte, Jaime A Cummings, Gary C Bergstrom. Trichothecene Genotype Composition of Fusarium graminearum Not Differentiated Among Isolates from Maize Stubble, Maize Ears, Wheat Spikes, and the Atmosphere in New York.
Phytopathology.
2015 May; 105(5):695-9. doi:
10.1094/phyto-10-14-0266-r. [PMID: 25651052] - N Broekaert, M Devreese, T De Mil, S Fraeyman, S De Baere, S De Saeger, P De Backer, S Croubels. Development and validation of an LC-MS/MS method for the toxicokinetic study of deoxynivalenol and its acetylated derivatives in chicken and pig plasma.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2014 Nov; 971(?):43-51. doi:
10.1016/j.jchromb.2014.09.012. [PMID: 25264912] - Pierri Spolti, Emerson M Del Ponte, Jaime A Cummings, Yanhong Dong, Gary C Bergstrom. Fitness attributes of Fusarium graminearum isolates from wheat in New York possessing a 3-ADON or 15-ADON trichothecene genotype.
Phytopathology.
2014 May; 104(5):513-9. doi:
10.1094/phyto-07-13-0206-r. [PMID: 24283539] - Wenda Wu, Hui-Ren Zhou, Kaiyu He, Xiao Pan, Yoshiko Sugita-Konishi, Maiko Watanabe, Haibin Zhang, James J Pestka. Role of cholecystokinin in anorexia induction following oral exposure to the 8-ketotrichothecenes deoxynivalenol, 15-acetyldeoxynivalenol, 3-acetyldeoxynivalenol, fusarenon X, and nivalenol.
Toxicological sciences : an official journal of the Society of Toxicology.
2014 Apr; 138(2):278-89. doi:
10.1093/toxsci/kft335. [PMID: 24385417] - Fang Ji, Hua Li, Jianhong Xu, Jianrong Shi. Enzyme-linked immunosorbent-assay for Deoxynivalenol (DON).
Toxins.
2011 08; 3(8):968-78. doi:
10.3390/toxins3080968. [PMID: 22069751] - Piyum A Khatibi, Sean A Newmister, Ivan Rayment, Susan P McCormick, Nancy J Alexander, David G Schmale. Bioprospecting for trichothecene 3-O-acetyltransferases in the fungal genus Fusarium yields functional enzymes with different abilities to modify the mycotoxin deoxynivalenol.
Applied and environmental microbiology.
2011 Feb; 77(4):1162-70. doi:
10.1128/aem.01738-10. [PMID: 21169453] - Patrick J Doyle, Mehdi Arbabi-Ghahroudi, Nathalie Gaudette, Gordon Furzer, Marc E Savard, Steve Gleddie, Michael D McLean, C Roger Mackenzie, J Christopher Hall. Cloning, expression, and characterization of a single-domain antibody fragment with affinity for 15-acetyl-deoxynivalenol.
Molecular immunology.
2008 Aug; 45(14):3703-13. doi:
10.1016/j.molimm.2008.06.005. [PMID: 18632156] - Jing-Bo Zhang, He-Ping Li, Fu-Jun Dang, Bo Qu, Yu-Bin Xu, Chun-Sen Zhao, Yu-Cai Liao. Determination of the trichothecene mycotoxin chemotypes and associated geographical distribution and phylogenetic species of the Fusarium graminearum clade from China.
Mycological research.
2007 Aug; 111(Pt 8):967-75. doi:
10.1016/j.mycres.2007.06.008. [PMID: 17716884] - Shuichi Ohsato, Tetsuko Ochiai-Fukuda, Takumi Nishiuchi, Naoko Takahashi-Ando, Shinzo Koizumi, Hiroshi Hamamoto, Toshiaki Kudo, Isamu Yamaguchi, Makoto Kimura. Transgenic rice plants expressing trichothecene 3-O-acetyltransferase show resistance to the Fusarium phytotoxin deoxynivalenol.
Plant cell reports.
2007 Apr; 26(4):531-8. doi:
10.1007/s00299-006-0251-1. [PMID: 17031651] - G S Eriksen, H Pettersson, J E Lindberg. Absorption, metabolism and excretion of 3-acetyl DON in pigs.
Archiv fur Tierernahrung.
2003 Oct; 57(5):335-45. doi:
10.1080/00039420310001607699. [PMID: 14620907] - G Sundstøl Eriksen, H Pettersson. Lack of de-epoxidation of type B trichothecenes in incubates with human faeces.
Food additives and contaminants.
2003 Jun; 20(6):579-82. doi:
10.1080/0265203031000102573. [PMID: 12881132] - Fabricie Marcele Wilbert, Carlos Kemmelmeier. Identification of deoxynivalenol, 3-acetyldeoxynivalenol, and zearalenone in galactose oxidase-producing isolates of Fusarium graminearum.
Journal of basic microbiology.
2003; 43(2):148-57. doi:
10.1002/jobm.200390015. [PMID: 12746857] - B A Rotter, B K Thompson, M Lessard, H L Trenholm, H Tryphonas. Influence of low-level exposure to Fusarium mycotoxins on selected immunological and hematological parameters in young swine.
Fundamental and applied toxicology : official journal of the Society of Toxicology.
1994 Jul; 23(1):117-24. doi:
10.1006/faat.1994.1087. [PMID: 7958555] - K O'Neill, A P Damoglou, M F Patterson. The stability of deoxynivalenol and 3-acetyl deoxynivalenol to gamma irradiation.
Food additives and contaminants.
1993 Mar; 10(2):209-15. doi:
10.1080/02652039309374143. [PMID: 8314397] - E Usleber, V Renz, E Märtlbauer, G Terplan. Studies on the application of enzyme immunoassays for the Fusarium mycotoxins deoxynivalenol, 3-acetyldeoxynivalenol, and zearalenone.
Zentralblatt fur Veterinarmedizin. Reihe B. Journal of veterinary medicine. Series B.
1992 Oct; 39(8):617-27. doi:
10.1111/j.1439-0450.1992.tb01213.x. [PMID: 1462727] - . .
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