11-Hydroxytetrahydrocannabinol (BioDeep_00001874469)
Main id: BioDeep_00000055157
代谢物信息卡片
11-Hydroxytetrahydrocannabinol
化学式: C21H30O3 (330.21948299999997)
中文名称: 11-羟基-Δ9-四氢大麻酚
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CCCCCC1=CC(=C2C3C=C(CCC3C(OC2=C1)(C)C)CO)O
InChI: InChI=1S/C21H30O3/c1-4-5-6-7-14-11-18(23)20-16-10-15(13-22)8-9-17(16)21(2,3)24-19(20)12-14/h10-12,16-17,22-23H,4-9,13H2,1-3H3/t16-,17-/m1/s1
数据库引用编号
6 个数据库交叉引用编号
- ChEBI: CHEBI:77270
- PubChem: 644022
- ChEMBL: CHEMBL3229459
- CAS: 36557-05-8
- CAS: 34675-49-5
- KEGG: C22778
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Gabriela I Patilea-Vrana, Jashvant D Unadkat. Development and Verification of a Linked Δ 9-THC/11-OH-THC Physiologically Based Pharmacokinetic Model in Healthy, Nonpregnant Population and Extrapolation to Pregnant Women.
Drug metabolism and disposition: the biological fate of chemicals.
2021 07; 49(7):509-520. doi:
10.1124/dmd.120.000322. [PMID: 33952608] - Angela Gasse, Marielle Vennemann, Helga Köhler, Jennifer Schürenkamp. Toxicogenetic analysis of Δ9-THC-metabolizing enzymes.
International journal of legal medicine.
2020 Nov; 134(6):2095-2103. doi:
10.1007/s00414-020-02380-3. [PMID: 32712703] - Christoph Hassenberg, Florian Clausen, Grete Hoffmann, Armido Studer, Jennifer Schürenkamp. Investigation of phase II metabolism of 11-hydroxy-Δ-9-tetrahydrocannabinol and metabolite verification by chemical synthesis of 11-hydroxy-Δ-9-tetrahydrocannabinol-glucuronide.
International journal of legal medicine.
2020 Nov; 134(6):2105-2119. doi:
10.1007/s00414-020-02387-w. [PMID: 32808050] - Charles Guidet, Matthieu Gregoire, Alexiane Le Dreau, Benedicte Vrignaud, Guillaume Deslandes, Catherine Monteil-Ganière. Cannabis intoxication after accidental ingestion in infants: urine and plasma concentrations of Δ-9-tetrahydrocannabinol (THC), THC-COOH and 11-OH-THC in 10 patients.
Clinical toxicology (Philadelphia, Pa.).
2020 05; 58(5):421-423. doi:
10.1080/15563650.2019.1655569. [PMID: 31441354] - William R Wolowich, Robert Greif, Maren Kleine-Brueggeney, Werner Bernhard, Lorenz Theiler. Minimal Physiologically Based Pharmacokinetic Model of Intravenously and Orally Administered Delta-9-Tetrahydrocannabinol in Healthy Volunteers.
European journal of drug metabolism and pharmacokinetics.
2019 Oct; 44(5):691-711. doi:
10.1007/s13318-019-00559-7. [PMID: 31114948] - Gabriela I Patilea-Vrana, Olena Anoshchenko, Jashvant D Unadkat. Hepatic Enzymes Relevant to the Disposition of (-)-∆9-Tetrahydrocannabinol (THC) and Its Psychoactive Metabolite, 11-OH-THC.
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2019 03; 47(3):249-256. doi:
10.1124/dmd.118.085548. [PMID: 30567877] - Julia Sophie Schneider, Angela Gasse, Marianne Schürenkamp, Ursula Sibbing, Sabrina Banken, Heidi Pfeiffer, Jennifer Schürenkamp, Marielle Vennemann. Multiplex analysis of genetic polymorphisms within UGT1A9, a gene involved in phase II of Δ9-THC metabolism.
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2019 Mar; 133(2):365-372. doi:
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Forensic science international.
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10.1016/j.forsciint.2018.11.005. [PMID: 30481665] - Huan Huang, Avery L McIntosh, Gregory G Martin, Lawrence J Dangott, Ann B Kier, Friedhelm Schroeder. Structural and Functional Interaction of Δ9-Tetrahydrocannabinol with Liver Fatty Acid Binding Protein (FABP1).
Biochemistry.
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