Triglycerol monolaurate (BioDeep_00001874409)
代谢物信息卡片
N-Nitrosobis(2-oxopropyl)amine
化学式: C6H10N2O3 (158.0691)
中文名称: 三聚甘油单月桂酸酯
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC(=O)CN(CC(=O)C)N=O
InChI: InChI=1S/C6H10N2O3/c1-5(9)3-8(7-11)4-6(2)10/h3-4H2,1-2H3
描述信息
D009676 - Noxae > D002273 - Carcinogens
D009676 - Noxae > D009153 - Mutagens
同义名列表
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
| 亚细胞结构定位 | 关联基因列表 |
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文献列表
- Mika Hori, Michihiro Mutoh, Rikako Ishigamori, Toshio Imai, Mami Takahashi. Activated Ductal Proliferation Induced by N-Nitrosobis (2-oxopropyl)amine in Fat-infiltrated Pancreas of KK-Ay Mice.
In vivo (Athens, Greece).
2018 May; 32(3):499-505. doi:
10.21873/invivo.11267. [PMID: 29695552] - B Karthik Grandhi, Arvind Thakkar, Jeffrey Wang, Sunil Prabhu. A novel combinatorial nanotechnology-based oral chemopreventive regimen demonstrates significant suppression of pancreatic cancer neoplastic lesions.
Cancer prevention research (Philadelphia, Pa.).
2013 Oct; 6(10):1015-1025. doi:
10.1158/1940-6207.capr-13-0172. [PMID: 24072676] - Fumiaki Nozawa, Mehmet Yalniz, Murat Saruc, Jens Standop, Hiroshi Egami, Parviz M Pour. Effects of porcine pancreatic enzymes on the pancreas of hamsters. Part 2: carcinogenesis studies.
JOP : Journal of the pancreas.
2012 Sep; 13(5):482-7. doi:
10.6092/1590-8577/663. [PMID: 22964954] - Tsukasa Kitahashi, Shoko Ikawa, Akika Sakamoto, Yoshihiro Nomura, Toshifumi Tsujiuchi, Kenji Shimizu, Shuji Sasabe, Eun Young Park, Yasushi Nakamura, Masahiro Tsutsumi, Kenji Sato. Ingestion of proteoglycan fraction from shark cartilage increases serum inhibitory activity against matrix metalloproteinase-9 and suppresses development of N-nitrosobis(2-oxopropyl)amine-induced pancreatic duct carcinogenesis in hamster.
Journal of agricultural and food chemistry.
2012 Feb; 60(4):940-5. doi:
10.1021/jf203613b. [PMID: 22225405] - Ezar Hafez, Tetsuyuki Takahashi, Hirohisa Ogawa, Makoto Sato, Tokiko Nakai, Chie Takasu, Hisanori Uehara, Keisuke Izumi. High susceptibility to zymbal gland and intestinal carcinogenesis in diabetic Otsuka long-evans Tokushima Fatty rats.
Journal of toxicologic pathology.
2011 Dec; 24(4):187-93. doi:
10.1293/tox.24.187. [PMID: 22319230] - Mika Hori, Tsukasa Kitahashi, Toshio Imai, Rikako Ishigamori, Shinji Takasu, Michihiro Mutoh, Takashi Sugimura, Keiji Wakabayashi, Mami Takahashi. Enhancement of carcinogenesis and fatty infiltration in the pancreas in N-nitrosobis(2-oxopropyl)amine-treated hamsters by high-fat diet.
Pancreas.
2011 Nov; 40(8):1234-40. doi:
10.1097/mpa.0b013e318220e742. [PMID: 21989024] - Toshifumi Tsujiuchi, Kyoko Okabe, Nobuyuki Fukushima. Genetic and epigenetic alterations of lysophosphatidic Acid receptor genes in rodent tumors by experimental models.
Journal of toxicologic pathology.
2011 Sep; 24(3):143-8. doi:
10.1293/tox.24.143. [PMID: 22272054] - Juan Ruiz-Rabelo, Reyes Vázquez, Alvaro Arjona, Dolores Perea, Pedro Montilla, Isaac Túnez, Jordi Muntané, Javier Padillo. Improvement of capecitabine antitumoral activity by melatonin in pancreatic cancer.
Pancreas.
2011 Apr; 40(3):410-4. doi:
10.1097/mpa.0b013e318201ca4f. [PMID: 21178648] - Akika Sakamoto, Michishi Goya, Yoko Degawa, Masayuki Mitsui, Toshio Mori, Kazutoshi Tamura, Masahiro Tsutsumi. Promoting Effects of Sucrose-rich Diet on N-Nitrosobis (2-oxopropyl) amine-induced Pancreatic Carcinogenesis in Hamsters.
Journal of toxicologic pathology.
2010 Mar; 23(1):19-24. doi:
10.1293/tox.23.19. [PMID: 22272007] - Alvaro Arjona-Sánchez, Juan Ruiz-Rabelo, María D Perea, Reyes Vázquez, Adolfo Cruz, María del C Muñoz, Isaac Túnez, Jordi Muntané, Francisco J Padillo. Effects of capecitabine and celecoxib in experimental pancreatic cancer.
Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.].
2010; 10(5):641-7. doi:
10.1159/000288708. [PMID: 21051919] - M Kilian, J I Gregor, I Heukamp, K Helmecke, M Hanel, B Wassersleben, M K Walz, I Schimke, G Kristiansen, F A Wenger. Impact of Octreotide and SOM-230 on liver metastasis and hepatic lipidperoxidation in ductal pancreatic adenocarcinoma in Syrian Hamster.
Clinical & experimental metastasis.
2009; 26(7):719-27. doi:
10.1007/s10585-009-9271-x. [PMID: 19521786] - Chang-Yin Lee, Yi-Chao Hsu, Jir-You Wang, Chien-Chih Chen, Jen-Hwey Chiu. Chemopreventive effect of selenium and Chinese medicinal herbs on N-nitrosobis(2-oxopropyl)amine-induced hepatocellular carcinoma in Syrian hamsters.
Liver international : official journal of the International Association for the Study of the Liver.
2008 Jul; 28(6):841-55. doi:
10.1111/j.1478-3231.2008.01698.x. [PMID: 18346132] - Katsuhisa Sakano, Mami Takahashi, Michihiro Mutoh, Naoko Niho, Masami Komiya, Hidetaka Sato, Takuji Tanaka, Takashi Sugimura, Keiji Wakabayashi. Enhanced thyroid carcinogenicity of N-nitrosobis(2-oxopropyl)amine in Otsuka Long-Evans Tokushima Fatty rats, a model of type II diabetes mellitus.
Carcinogenesis.
2007 Oct; 28(10):2193-8. doi:
10.1093/carcin/bgm114. [PMID: 17510084] - Juan F Ruiz-Rabelo, Reyes Vázquez, María D Perea, Adolfo Cruz, Raul González, Ana Romero, María C Muñoz-Villanueva, Isaac Túnez, Pedro Montilla, Jordi Muntané, Francisco Javier Padillo. Beneficial properties of melatonin in an experimental model of pancreatic cancer.
Journal of pineal research.
2007 Oct; 43(3):270-5. doi:
10.1111/j.1600-079x.2007.00472.x. [PMID: 17803524] - Yoshito Takeuchi, Mami Takahashi, Katsuhisa Sakano, Michihiro Mutoh, Naoko Niho, Masafumi Yamamoto, Hidetaka Sato, Takashi Sugimura, Keiji Wakabayashi. Suppression of N-nitrosobis(2-oxopropyl)amine-induced pancreatic carcinogenesis in hamsters by pioglitazone, a ligand of peroxisome proliferator-activated receptor gamma.
Carcinogenesis.
2007 Aug; 28(8):1692-6. doi:
10.1093/carcin/bgm095. [PMID: 17449904] - José L Peñalvo, Anu Hopia, Herman Adlercreutz. Effect of sesamin on serum cholesterol and triglycerides levels in LDL receptor-deficient mice.
European journal of nutrition.
2006 Dec; 45(8):439-44. doi:
10.1007/s00394-006-0617-8. [PMID: 17039285] - I Heukamp, J I Gregor, M Kilian, C Kiewert, C A Jacobi, I Schimke, M K Walz, H Guski, F A Wenger. Influence of different dietary fat intake on liver metastasis and hepatic lipid peroxidation in BOP-induced pancreatic cancer in Syrian hamsters.
Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.].
2006; 6(1-2):96-102. doi:
10.1159/000090028. [PMID: 16327286] - J I Gregor, I Heukamp, M Kilian, C Kiewert, I Schimke, G Kristiansen, M K Walz, C A Jacobi, F A Wenger. Does enteral nutrition of dietary polyunsaturated fatty acids promote oxidative stress and tumour growth in ductal pancreatic cancer? Experimental trial in Syrian Hamster.
Prostaglandins, leukotrienes, and essential fatty acids.
2006 Jan; 74(1):67-74. doi:
10.1016/j.plefa.2005.08.007. [PMID: 16226437] - Maik Kilian, Jan Ilga Gregor, Ina Heukamp, Chris Braumann, Hans Guski, Ingolf Schimke, Martin Karl Walz, Christoph Andreas Jacobi, Frank Axel Wenger. Impact of taurolidin and octreotide on liver metastasis and lipid peroxidation after laparoscopy in chemical induced ductal pancreatic cancer.
Investigational new drugs.
2005 Mar; 23(2):157-64. doi:
10.1007/s10637-005-5861-x. [PMID: 15744592] - I Heukamp, M Kilian, J I Gregor, A Neumann, C A Jacobi, H Guski, I Schimke, M K Walz, F A Wenger. Effects of the antioxidative vitamins A, C and E on liver metastasis and intrametastatic lipid peroxidation in BOP-induced pancreatic cancer in Syrian hamsters.
Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.].
2005; 5(4-5):403-9. doi:
10.1159/000086541. [PMID: 15985764] - Fumiyo Takabayashi, Shoichi Tahara, Takao Kaneko, Yoshihiko Miyoshi, Noboru Harada. Accumulation of 8-oxo-2'-deoxyguanosine (as a biomarker of oxidative DNA damage) in the tissues of aged hamsters and change in antioxidant enzyme activities after single administration of N-nitrosobis(2-oxopropyl) amine.
Gerontology.
2004 Mar; 50(2):57-63. doi:
10.1159/000075556. [PMID: 14963372] - Fumiyo Takabayashi, Shoichi Tahara, Takao Kaneko, Noboru Harada. Effect of green tea catechins on oxidative DNA damage of hamster pancreas and liver induced by N-Nitrosobis(2-oxopropyl)amine and/or oxidized soybean oil.
BioFactors (Oxford, England).
2004; 21(1-4):335-7. doi:
10.1002/biof.552210165. [PMID: 15630222] - M Kilian, I Mautsch, C Braumann, I Schimke, H Guski, C A Jacobi, F A Wenger. Effects of taurolidine and octreotide on tumor growth and lipid peroxidation after staging-laparoscopy in ductal pancreatic cancer.
Prostaglandins, leukotrienes, and essential fatty acids.
2003 Oct; 69(4):261-7. doi:
10.1016/s0952-3278(03)00108-x. [PMID: 12907136] - Takao Kaneko, Shoichi Tahara, Fumiyo Takabayashi. Protective effect of fluvastatin, an HMG-CoA reductase inhibitor, on the formation of 8-oxo-2'-deoxyguanosine in the nuclear DNA of hamster pancreas after a single administration of N-nitrosobis(2-oxopropyl)amine.
Biological & pharmaceutical bulletin.
2003 Sep; 26(9):1245-8. doi:
10.1248/bpb.26.1245. [PMID: 12951466] - M Kilian, I Mautsch, J I Gregor, D Heinichen, C A Jacobi, I Schimke, H Guski, J M Müller, F A Wenger. Influence of conjugated and conventional linoleic acid on tumor growth and lipid peroxidation in pancreatic adenocarcinoma in hamster.
Prostaglandins, leukotrienes, and essential fatty acids.
2003 Jul; 69(1):67-72. doi:
10.1016/s0952-3278(03)00058-9. [PMID: 12878453] - M Kilian, I Mautsch, J I Gregor, P Stahlknecht, C A Jacobi, I Schimke, H Guski, F A Wenger. Influence of conjugated vs. conventional linoleic acid on liver metastasis and hepatic lipidperoxidation in BOP-induced pancreatic cancer in Syrian hamster.
Prostaglandins, leukotrienes, and essential fatty acids.
2002 Oct; 67(4):223-8. doi:
10.1054/plef.2002.0422. [PMID: 12401436] - Fumio Furukawa, Akiyoshi Nishikawa, Takeshi Chihara, Kan Shimpo, Hidehiko Beppu, Hiroshi Kuzuya, In Seon Lee, Masao Hirose. Chemopreventive effects of Aloe arborescens on N-nitrosobis(2-oxopropyl)amine-induced pancreatic carcinogenesis in hamsters.
Cancer letters.
2002 Apr; 178(2):117-22. doi:
10.1016/s0304-3835(01)00840-0. [PMID: 11867195] - F A Wenger, M Kilian, J M Proske, H Guski, I Schimke, C A Jacobi. The impact of laparoscopic biopsy of pancreatic lymph nodes on lipid peroxidation using helium and carbon dioxide in BOP-induced pancreatic cancer in hamsters.
Surgical endoscopy.
2001 Oct; 15(10):1150-5. doi:
10.1007/s004640090035. [PMID: 11727090] - F A Wenger, M Kilian, I Mautsch, C A Jacobi, A Steiert, F J Peter, H Guski, I Schimke, J M Müller. Influence of octreotide on liver metastasis and hepatic lipid peroxidation in BOP-induced pancreatic cancer in Syrian hamsters.
Pancreas.
2001 Oct; 23(3):266-72. doi:
10.1097/00006676-200110000-00007. [PMID: 11590322] - F A Wenger, M Kilian, J Ridders, P Stahlknecht, I Schimke, H Guski, C A Jacobi, J M Müller. Influence of antioxidative vitamins A, C and E on lipid peroxidation in BOP-induced pancreatic cancer in Syrian hamsters.
Prostaglandins, leukotrienes, and essential fatty acids.
2001 Sep; 65(3):165-71. doi:
10.1054/plef.2001.0305. [PMID: 11728167] - M B Schneider, H Matsuzaki, J Haorah, A Ulrich, J Standop, X Z Ding, T E Adrian, P M Pour. Prevention of pancreatic cancer induction in hamsters by metformin.
Gastroenterology.
2001 Apr; 120(5):1263-70. doi:
10.1053/gast.2001.23258. [PMID: 11266389] - J Permert, M Herrington, K Kazakoff, P M Pour, T E Adrian. Early changes in islet hormone secretion in the hamster pancreatic cancer model.
Teratogenesis, carcinogenesis, and mutagenesis.
2001; 21(1):59-67. doi:
10.1002/1520-6866(2001)21:1<59::aid-tcm6>3.0.co;2-v. [PMID: 11135321] - F A Wenger, M Kilian, C A Jacobi, I Mautsch, F J Peter, H Guski, I Schimke, J M Müller. Effects of octreotide on liver metastasis and intrametastatic lipid peroxidation in experimental pancreatic cancer.
Oncology.
2001; 60(3):282-8. doi:
10.1159/000055330. [PMID: 11340381] - H Y Son, A Nishikawa, F Furukawa, I S Lee, T Ikeda, M Miyauchi, H Nakamura, M Hirose. Modifying effects of 4-phenylbutyl isothiocyanate on N-nitrosobis(2-oxopropyl)amine-induced tumorigenesis in hamsters.
Cancer letters.
2000 Nov; 160(2):141-7. doi:
10.1016/s0304-3835(00)00570-x. [PMID: 11053643] - B C Roy, R Peterson, S Mallik, A D Campiglia. Synthesis and fluorescence properties of new fluorescent, polymerizable, metal-chelating lipids.
The Journal of organic chemistry.
2000 Jun; 65(12):3644-51. doi:
10.1021/jo991836r. [PMID: 10864747] - A Nishikawa, F Furukawa, K Kasahara, Z Tanakamaru, M Miyauchi, H Nakamura, T Ikeda, T Imazawa, M Hirose. Failure of phenethyl isothiocyanate to inhibit hamster tumorigenesis induced by N-nitrosobis(2-oxopropyl)amine when given during the post-initiation phase.
Cancer letters.
1999 Jul; 141(1-2):109-15. doi:
10.1016/s0304-3835(99)00089-0. [PMID: 10454250] - F Furukawa, A Nishikawa, T Imazawa, K Kasahara, M Takahashi. Enhancing effects of quinacrine on development of hepatopancreatic lesions in N-nitrosobis(2-oxopropyl)amine-initiated hamsters.
Japanese journal of cancer research : Gann.
1998 Feb; 89(2):131-6. doi:
10.1111/j.1349-7006.1998.tb00540.x. [PMID: 9548439] - D F Birt, P M Pour, D L Nagel, T Barnett, D Blackwood, E Duysen. Dietary energy restriction does not inhibit pancreatic carcinogenesis by N-nitrosobis-2-(oxopropyl)amine in the Syrian hamster.
Carcinogenesis.
1997 Nov; 18(11):2107-11. doi:
10.1093/carcin/18.11.2107. [PMID: 9395209] - F Takabayashi, N Harada, S Tahara, T Kaneko, Y Hara. Effect of green tea catechins on the amount of 8-hydroxydeoxyguanosine (8-OHdG) in pancreatic and hepatic DNA after a single administration of N-nitrosobis(2-oxopropyl)amine (BOP).
Pancreas.
1997 Aug; 15(2):109-12. doi:
10.1097/00006676-199708000-00001. [PMID: 9260194] - F Furukawa, A Nishikawa, T Enami, M Mitsui, T Imazawa, Z Tanakamaru, H C Kim, I S Lee, K Kasahara, M Takahashi. Promotional effects of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) on N-nitrosobis(2-oxopropyl)amine (BOP)-initiated carcinogenesis in hamsters.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
1997 Mar; 35(3-4):387-92. doi:
10.1016/s0278-6915(97)00127-0. [PMID: 9207901] - T Yamamoto, K Yamamoto, H Sinohara. Inter-alpha-trypsin inhibitor and its related proteins in Syrian hamster urine and plasma.
Journal of biochemistry.
1996 Jul; 120(1):145-52. doi:
10.1093/oxfordjournals.jbchem.a021377. [PMID: 8864857] - Y Ikematsu, T Tomioka, S Yamanaka, Y Tajima, T Tsunoda, T Kanematsu. Bilioenterostomy enhances biliary carcinogenesis in hamsters.
Carcinogenesis.
1996 Jul; 17(7):1505-9. doi:
10.1093/carcin/17.7.1505. [PMID: 8706256] - A Nishikawa, F Furukawa, S Ikezaki, Z Y Tanakamaru, F L Chung, M Takahashi, Y Hayashi. Chemopreventive effects of 3-phenylpropyl isothiocyanate on hamster lung tumorigenesis initiated with N-nitrosobis(2-oxopropyl)amine.
Japanese journal of cancer research : Gann.
1996 Feb; 87(2):122-6. doi:
10.1111/j.1349-7006.1996.tb03148.x. [PMID: 8609059] - K Kazakoff, T Cardesa, J Liu, T E Adrian, D Bagchi, M Bagchi, D F Birt, P M Pour. Effects of voluntary physical exercise on high-fat diet-promoted pancreatic carcinogenesis in the hamster model.
Nutrition and cancer.
1996; 26(3):265-79. doi:
10.1080/01635589609514483. [PMID: 8910909] - J Zhang, V L Go. High fat diet, lipid peroxidation, and pancreatic carcinogenesis.
Advances in experimental medicine and biology.
1996; 399(?):165-72. doi:
10.1007/978-1-4613-1151-5_13. [PMID: 8937556] - M L Clapper, M Wood, K Leahy, D Lang, S Miknyoczki, B A Ruggeri. Chemopreventive activity of Oltipraz against N-nitrosobis(2-oxopropyl)amine (BOP)-induced ductal pancreatic carcinoma development and effects on survival of Syrian golden hamsters.
Carcinogenesis.
1995 Sep; 16(9):2159-65. doi:
10.1093/carcin/16.9.2159. [PMID: 7554069] - M J Appel, R A Woutersen. Effects of dietary fish oil (MaxEPA) on N-nitrosobis(2-oxopropyl)amine (BOP)-induced pancreatic carcinogenesis in hamsters.
Cancer letters.
1995 Aug; 94(2):179-89. doi:
10.1016/0304-3835(95)03848-q. [PMID: 7634246] - F Furukawa, A Nishikawa, H Yoshimura, M Mitsui, T Imazawa, S Ikezaki, M Takahashi. Effects of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) on N-nitrosobis(2-oxopropyl)amine (BOP)-initiated carcinogenesis in hamsters.
Cancer letters.
1994 Oct; 86(1):75-82. doi:
10.1016/0304-3835(94)90182-1. [PMID: 7954358] - T Ogawa, T Makino, N Hirose, M Sugano. Lack of influence of low blood cholesterol levels on pancreatic carcinogenesis after initiation with N-nitrosobis(2-oxopropyl)amine in Syrian golden hamsters.
Carcinogenesis.
1994 Aug; 15(8):1663-6. doi:
10.1093/carcin/15.8.1663. [PMID: 8055648] - M K Herrington, J Permert, K R Kazakoff, K A Zucker, A J Bilchik, P M Pour, T E Adrian. Effects of raw soya diet and cholecystokinin receptor blockade on pancreatic growth and tumor initiation in the hamster.
Cancer letters.
1994 Jul; 82(1):7-16. doi:
10.1016/0304-3835(94)90140-6. [PMID: 8033071] - K Kazakoff, P Iversen, T Lawson, J Baron, F P Guengerich, P M Pour. Involvement of cytochrome P450 2E1-like isoform in the activation of N-nitrosobis(2-oxopropyl)amine in the rat nasal mucosa.
European journal of cancer. Part B, Oral oncology.
1994 May; 30B(3):179-85. doi:
10.1016/0964-1955(94)90088-4. [PMID: 7920164] - M Sato, F Furukawa, A Nishikawa, K Mitsumori, T Imazawa, M Takahashi. Analysis of proliferative activity in renal lesions induced by N-nitrosobis(2-oxopropyl)amine (BOP) in male Syrian golden hamsters.
Cancer letters.
1994 Apr; 79(1):91-9. doi:
10.1016/0304-3835(94)90068-x. [PMID: 7910517] - M J Appel, A van Garderen-Hoetmer, R A Woutersen. Effects of dietary linoleic acid on pancreatic carcinogenesis in rats and hamsters.
Cancer research.
1994 Apr; 54(8):2113-20. doi:
NULL. [PMID: 8174115] - K Mitsumori, F Furukawa, M Sato, H Yoshimura, T Imazawa, A Nishikawa, M Takahashi. Promoting effects of ethinyl estradiol on development of renal proliferative lesions induced by N-nitrosobis (2-oxopropyl)amine in female Syrian golden hamsters.
Journal of cancer research and clinical oncology.
1994; 120(3):131-6. doi:
10.1007/bf01202190. [PMID: 8263008] - D M Kokkinakis, V Subbarao. The significance of DNA damage, its repair and cell proliferation during carcinogen treatment in the initiation of pancreatic cancer in the hamster model.
Cancer research.
1993 Jun; 53(12):2790-5. doi:
NULL. [PMID: 8504421] - M K Herrington, J Permert, K R Kazakoff, P M Pour, K A Zuker, A J Bilchik, T E Adrian. Effects of high fat diet and cholecystokinin receptor blockade on pancreatic growth and tumor initiation in the hamster.
Carcinogenesis.
1993 May; 14(5):1021-6. doi:
10.1093/carcin/14.5.1021. [PMID: 7684953] - B Ahrén, A Andrén-Sandberg. Glucose tolerance and insulin secretion in experimental pancreatic cancer in the Syrian hamster.
Research in experimental medicine. Zeitschrift fur die gesamte experimentelle Medizin einschliesslich experimenteller Chirurgie.
1993; 193(1):21-6. doi:
10.1007/bf02576207. [PMID: 8446769] - T Ogawa, T Makino, K Kosahara, A Koga, F Nakayama. Promoting effects of both dietary cholesterol and cholestyramine on pancreatic carcinogenesis initiated by N-nitrosobis(2-oxopropyl)amine in Syrian golden hamsters.
Carcinogenesis.
1992 Nov; 13(11):2047-52. doi:
10.1093/carcin/13.11.2047. [PMID: 1423874] - M Hirota, P M Pour, M A Tempero, W G Chaney. Purification and analysis of glycoproteins bearing blood group-A determinants from hamster pancreatic ductal adenocarcinomas.
Carcinogenesis.
1992 Oct; 13(10):1829-33. doi:
10.1093/carcin/13.10.1829. [PMID: 1385001] - D M Kokkinakis. Alkylation of rodent tissue DNA induced by N-nitrosobis(2-hydroxypropyl)amine.
Carcinogenesis.
1992 May; 13(5):759-65. doi:
10.1093/carcin/13.5.759. [PMID: 1586988] - M Meijers, R A Woutersen, A van Garderen-Hoetmer, G H Bakker, F H de Jong, J A Foekens, J G Klijn. Effects of sandostatin and castration on pancreatic carcinogenesis in rats and hamsters.
International journal of cancer.
1992 Jan; 50(2):246-51. doi:
10.1002/ijc.2910500214. [PMID: 1730518] - M Solé, A Cardesa, J Domingo, U Mohr. The carcinogenic effect of 2,2-dioxopropylnitrosamine on the renal pelvic epithelium of Sprague-Dawley rats, after chronic subcutaneous injections.
Journal of cancer research and clinical oncology.
1992; 118(3):222-7. doi:
10.1007/bf01410138. [PMID: 1548288] - T Shirai, A Yamamoto, S Iwasaki, S Tamano, T Masui. Induction of invasive carcinomas of the seminal vesicles and coagulating glands of F344 rats by administration of N-methylnitrosourea or N-nitrosobis(2-oxopropyl)amine and followed by testosterone propionate with or without high-fat diet.
Carcinogenesis.
1991 Nov; 12(11):2169-73. doi:
10.1093/carcin/12.11.2169. [PMID: 1934306] - M M Abad, J I Paz Bouza, M J Pedraz, E Muñoz. Modifications in CA 19-9 serum levels in BOP receiving hamsters treated with nicotinamide.
The International journal of biological markers.
1991 Oct; 6(4):256. doi:
10.1177/172460089100600408. [PMID: 1839033] - P M Pour, K Groot, K Kazakoff, K Anderson, A V Schally. Effects of high-fat diet on the patterns of prostatic cancer induced in rats by N-nitrosobis(2-oxopropyl)amine and testosterone.
Cancer research.
1991 Sep; 51(18):4757-61. doi:
NULL. [PMID: 1909929] - M Meijers, R A Woutersen, A van Garderen-Hoetmer, G H Bakker, F H de Jong, J A Foekens, J G Klijn. Effects of castration, alone and in combination with aminoglutethimide, on growth of (pre)neoplastic lesions in exocrine pancreas of rats and hamsters.
Carcinogenesis.
1991 Sep; 12(9):1707-13. doi:
10.1093/carcin/12.9.1707. [PMID: 1832592] - J Bax, C Schippers-Gillissen, R A Woutersen, E Scherer. Cell specific DNA alkylation in target and non-target organs of N-nitrosobis(2-oxopropyl)amine-induced carcinogenesis in hamster and rat.
Carcinogenesis.
1991 Apr; 12(4):583-90. doi:
10.1093/carcin/12.4.583. [PMID: 2013123] - D M Kokkinakis. Differences between pancreatropic nitrosamine carcinogens and N-nitrosodimethylamine in methylating DNA in various tissues of hamsters and rats.
Chemico-biological interactions.
1991; 78(2):167-81. doi:
10.1016/0009-2797(91)90012-v. [PMID: 2040022] - Y Kise, M Yamamura, M Kogata, S Uetsuji, H Takada, K Hioki, M Yamamoto. Inhibitory effect of selenium on hamster pancreatic cancer induction by N'-nitrosobis(2-oxopropyl)amine.
International journal of cancer.
1990 Jul; 46(1):95-100. doi:
10.1002/ijc.2910460118. [PMID: 2365502] - B Szende, G Srkalovic, K Groot, K Lapis, A V Schally. Regression of nitrosamine-induced pancreatic cancers in hamsters treated with luteinizing hormone-releasing hormone antagonists or agonists.
Cancer research.
1990 Jun; 50(12):3716-21. doi:
NULL. [PMID: 2160323] - D F Birt, A D Julius, E Dwork, T Hanna, L T White, P M Pour. Comparison of the effects of dietary beef tallow and corn oil on pancreatic carcinogenesis in the hamster model.
Carcinogenesis.
1990 May; 11(5):745-8. doi:
10.1093/carcin/11.5.745. [PMID: 2335005] - D M Kokkinakis. Differences in DNA-guanine alkylation between male Sprague-Dawley rats and Syrian hamsters following exposure to a single dose of pancreatic nitrosamine carcinogens.
Chemical research in toxicology.
1990 Mar; 3(2):150-6. doi:
10.1021/tx00014a011. [PMID: 2130943] - M Del Mar Abad, J I Paz, M J Pedraz, E Muñoz, A Bullón. Immunohistochemical modifications of 'B cells' in experimentally-induced pancreatic cancer--correlation with serum insulin values.
The International journal of biological markers.
1990 Jan; 5(1):31-4. doi:
10.1177/172460089000500106. [PMID: 2172410] - J Bax, P M Pour, D L Nagel, T A Lawson, R A Woutersen, E Scherer. Long-term persistence of DNA alkylation in hamster tissues after N-nitrosobis(2-oxopropyl)amine.
Journal of cancer research and clinical oncology.
1990; 116(2):149-55. doi:
10.1007/bf01612669. [PMID: 2324157] - P M Pour, R H Bell. Alteration of pancreatic endocrine cell patterns and their secretion during pancreatic carcinogenesis in the hamster model.
Cancer research.
1989 Nov; 49(22):6396-400. doi:
NULL. [PMID: 2572321] - M Abad, J I Paz, M J Pedraz, E Muñoz, A Bullón. Experimental pancreatic adenocarcinoma: an immunohistochemical study for CA 19-9 and its correlation with serum levels.
The International journal of biological markers.
1989 Oct; 4(4):229-32. doi:
10.1177/172460088900400409. [PMID: 2628503] - M Takahashi, F Furukawa, M Takahashi, S Nagase, K Imaida, Y Hayashi. Elevated activity of pancreatic type amylase in the urine as an early indicator of pancreatic tumors in hamsters.
International journal of pancreatology : official journal of the International Association of Pancreatology.
1989 Jul; 5(1):47-53. doi:
10.1007/bf02925697. [PMID: 2473147] - T Toyo'oka, F Furukawa, T Suzuki, Y Saito, M Takahashi, Y Hayashi, S Uzu, K Imai. Determination of thiols and disulfides in normal rat tissues and hamster pancreas treated with N-nitrosobis(2-oxopropyl)amine using 4-(aminosulfonyl)-7-fluoro-2,1,3-benzoxadiazole and ammonium 7-fluoro-2,1,3-benzoxadiazole-4-sulfonate.
Biomedical chromatography : BMC.
1989 Jul; 3(4):166-72. doi:
10.1002/bmc.1130030406. [PMID: 2590728] - D M Kokkinakis, D G Scarpelli. DNA alkylation in the hamster induced by two pancreatic carcinogens.
Cancer research.
1989 Jun; 49(12):3184-9. doi:
NULL. [PMID: 2720674] - P F Zucker, M C Archer. Alterations in pancreatic islet function produced by carcinogenic nitrosamines in the Syrian hamster.
The American journal of pathology.
1988 Dec; 133(3):573-7. doi:
NULL. [PMID: 3059807] - B J Thomas, W Lijinsky. DNA alkylation by nitrosobis-(2-oxopropyl)amine in rats of different ages.
Japanese journal of cancer research : Gann.
1988 Sep; 79(9):1039-42. doi:
10.1111/j.1349-7006.1988.tb00071.x. [PMID: 3142834] - W Lijinsky, B J Thomas, R M Kovatch. Effects of feminization of male F344 rats on induction of tumors and on nucleic acid alkylation by nitrosobis-(2-oxopropyl)amine.
Chemico-biological interactions.
1988; 66(1-2):111-9. doi:
10.1016/0009-2797(88)90045-2. [PMID: 3383283] - D F Birt, J C Pelling, P M Pour, M G Tibbels, L Schweickert, E Bresnick. Enhanced pancreatic and skin tumorigenesis in cabbage-fed hamsters and mice.
Carcinogenesis.
1987 Jul; 8(7):913-7. doi:
10.1093/carcin/8.7.913. [PMID: 3594724] - D F Birt, A D Julius, C E Runice, S Salmasi. Effects of dietary selenium on bis(2-oxopropyl)nitrosamine-induced carcinogenesis in Syrian golden hamsters.
Journal of the National Cancer Institute.
1986 Dec; 77(6):1281-6. doi:
NULL. [PMID: 3467117] - W Lijinsky, R M Kovatch. The effect of age on susceptibility of rats to carcinogenesis by two nitrosamines.
Japanese journal of cancer research : Gann.
1986 Dec; 77(12):1222-6. doi:
NULL. [PMID: 3102427] - M A Moore, T Nakamura, T Shirai, A Ichihara, N Ito. Immunohistochemical demonstration of increased glucose-6-phosphate dehydrogenase in preneoplastic and neoplastic lesions induced by propylnitrosamines in F344 rats and Syrian hamsters.
Japanese journal of cancer research : Gann.
1986 Feb; 77(2):131-8. doi:
NULL. [PMID: 3082825] - P M Pour, D F Birt. Effect of dietary protein on N-nitrosobis(2-oxopropyl)amine-induced carcinogenesis and on spontaneous diseases in Syrian golden hamsters.
Journal of the National Cancer Institute.
1986 Jan; 76(1):67-72. doi:
NULL. [PMID: 3455744] - M S Rao, V Subbarao, D G Scarpelli. Carcinogenic effect of N-nitrosobis (2-oxopropyl)amine in newborn rats.
Carcinogenesis.
1985 Sep; 6(9):1395-7. doi:
10.1093/carcin/6.9.1395. [PMID: 4028337] - D F Birt, P M Pour. Effects of the interaction of dietary fat and protein on N-nitrosobis(2-oxopropyl)amine-induced carcinogenesis and spontaneous lesions in Syrian golden hamsters.
Journal of the National Cancer Institute.
1985 May; 74(5):1121-7. doi:
NULL. [PMID: 3858580] - Y Mori, H Yamazaki, K Toyoshi, T Makino, T Obara, Y Yokose, Y Konishi. Mutagenic activation of carcinogenic N-nitrosopropylamines by rat liver: evidence for a cytochrome P-450 dependent reaction.
Carcinogenesis.
1985 Mar; 6(3):415-20. doi:
10.1093/carcin/6.3.415. [PMID: 3884171] - D F Birt, K Patil, P M Pour. Comparative studies on the effects of semipurified and commercial diet on longevity and spontaneous and induced lesions in the Syrian golden hamster.
Nutrition and cancer.
1985; 7(3):167-77. doi:
10.1080/01635588509513851. [PMID: 4080565] - L Rosenberg, W P Duguid, R A Brown. Development of experimental cancer in the head of the pancreas by surgical induction of tissue injury.
American journal of surgery.
1984 Jan; 147(1):146-51. doi:
10.1016/0002-9610(84)90049-7. [PMID: 6691541] - D F Birt, P M Pour. Increased tumorigenesis induced by N-nitrosobis(2-oxopropyl)amine in Syrian golden hamsters fed high-fat diets.
Journal of the National Cancer Institute.
1983 Jun; 70(6):1135-8. doi:
NULL. [PMID: 6574283] - D F Birt, S Sayed, M H Davies, P Pour. Sex differences in the effects of retinoids on carcinogenesis by N-nitrosobis(2-oxopropyl)amine in Syrian hamsters.
Cancer letters.
1981 Oct; 14(1):13-21. doi:
10.1016/0304-3835(81)90004-5. [PMID: 6457685] - M Takahashi, S Nagase, M Takahashi, T Kokubo, Y Hayashi. Changes of amylase during experimental pancreatic carcinogenesis in hamsters.
Gan.
1981 Aug; 72(4):615-9. doi:
NULL. [PMID: 6171474] - C E Whalley, Z M Iqbal, S S Epstein. In vivo and microsomal metabolism of the pancreatic carcinogen N-nitrosobis(2-oxopropyl)amine by the Syrian golden hamster.
Cancer research.
1981 Feb; 41(2):482-6. doi:
NULL. [PMID: 7448796] - K H Leung, M C Archer. Urinary metabolites of N-nitrosodipropylamine, N-nitroso-2-hydroxypropylpropylamine and N-nitroso-2-oxopropylpropylamine in the rat.
Carcinogenesis.
1981; 2(9):859-62. doi:
10.1093/carcin/2.9.859. [PMID: 7296770] - P Pour, R Gingell, R Langenbach, D Nagel, C Grandjean, T Lawson, S Salmasi. Carcinogenicity of N-nitrosomethyl(2-oxopropyl)amine in Syrian hamsters.
Cancer research.
1980 Oct; 40(10):3585-90. doi:
. [PMID: 7438045] - R G Runge, P Pour. Blood group specificity of pancreatic tumor mucin.
Cancer letters.
1980 Oct; 10(4):351-7. doi:
10.1016/0304-3835(80)90053-1. [PMID: 6775800]
