9,11-Octadecadienoic acid (BioDeep_00001874170)
natural product
代谢物信息卡片
化学式: C18H32O2 (280.2402172)
中文名称: 9(E),11(E)-十八碳二烯酸
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CCCCCCC=CC=CCCCCCCCC(=O)O
InChI: InChI=1S/C18H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h7-10H,2-6,11-17H2,1H3,(H,19,20)/b8-7+,10-9+
数据库引用编号
7 个数据库交叉引用编号
- ChEBI: CHEBI:88464
- ChEBI: CHEBI:36025
- PubChem: 5282796
- ChEMBL: CHEMBL4529739
- CAS: 1839-11-8
- CAS: 544-71-8
- LOTUS: LTS0163502
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
10 个相关的物种来源信息
- 4210 - Asteraceae: LTS0163502
- 3708 - Brassica napus: 10.3389/FNUT.2022.822033
- 4221 - Carthamus: LTS0163502
- 122010 - Carthamus oxyacanthus: 10.1021/NP200780M
- 122010 - Carthamus oxyacanthus: LTS0163502
- 2759 - Eukaryota: LTS0163502
- 3398 - Magnoliopsida: LTS0163502
- 35493 - Streptophyta: LTS0163502
- 58023 - Tracheophyta: LTS0163502
- 33090 - Viridiplantae: LTS0163502
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- Birsen Aydın, Cansu Güler Şahin, Vedat Şekeroğlu, Zülal Atlı Şekeroğlu. Conjugated linoleic acid protects brain mitochondrial function in acrolein induced male rats.
Toxicology mechanisms and methods.
2021 Nov; 31(9):674-679. doi:
10.1080/15376516.2021.1952673
. [PMID: 34238125] - A M Abdelatty, O A M Badr, S A Mohamed, M S Khattab, Sh M Dessouki, O A A Farid, A A Elolimy, O G Sakr, M A Elhady, G Mehesen, M Bionaz. Long term conjugated linoleic acid supplementation modestly improved growth performance but induced testicular tissue apoptosis and reduced sperm quality in male rabbit.
PloS one.
2020; 15(1):e0226070. doi:
10.1371/journal.pone.0226070
. [PMID: 31923252] - Dorottya Nagy-Szakal, Dinesh K Barupal, Bohyun Lee, Xiaoyu Che, Brent L Williams, Ellie J R Kahn, Joy E Ukaigwe, Lucinda Bateman, Nancy G Klimas, Anthony L Komaroff, Susan Levine, Jose G Montoya, Daniel L Peterson, Bruce Levin, Mady Hornig, Oliver Fiehn, W Ian Lipkin. Insights into myalgic encephalomyelitis/chronic fatigue syndrome phenotypes through comprehensive metabolomics.
Scientific reports.
2018 07; 8(1):10056. doi:
10.1038/s41598-018-28477-9
. [PMID: 29968805] - A Abolghasemi, E Dirandeh, Z Ansari Pirsaraei, B Shohreh. Dietary conjugated linoleic acid supplementation alters the expression of genes involved in the endocannabinoid system in the bovine endometrium and increases plasma progesterone concentrations.
Theriogenology.
2016 Oct; 86(6):1453-1459. doi:
10.1016/j.theriogenology.2016.05.003
. [PMID: 27262886] - Suleyman Bulut, Ebru Bodur, Ridvan Colak, Husrev Turnagol. Effects of conjugated linoleic acid supplementation and exercise on post-heparin lipoprotein lipase, butyrylcholinesterase, blood lipid profile and glucose metabolism in young men.
Chemico-biological interactions.
2013 Mar; 203(1):323-9. doi:
10.1016/j.cbi.2012.09.022
. [PMID: 23073171] - Arion Kennedy, Angel Overman, Kathleen Lapoint, Robin Hopkins, Tiffany West, Chia-Chi Chuang, Kristina Martinez, Doris Bell, Michael McIntosh. Conjugated linoleic acid-mediated inflammation and insulin resistance in human adipocytes are attenuated by resveratrol.
Journal of lipid research.
2009 Feb; 50(2):225-32. doi:
10.1194/jlr.m800258-jlr200
. [PMID: 18776171] - Robert Ringseis, Nadja Schulz, Daniela Saal, Klaus Eder. Troglitazone but not conjugated linoleic acid reduces gene expression and activity of matrix-metalloproteinases-2 and -9 in PMA-differentiated THP-1 macrophages.
The Journal of nutritional biochemistry.
2008 Sep; 19(9):594-603. doi:
10.1016/j.jnutbio.2007.08.003
. [PMID: 18155510] - Li-Fen Liu, Aparna Purushotham, Angela A Wendel, Martha A Belury. Combined effects of rosiglitazone and conjugated linoleic acid on adiposity, insulin sensitivity, and hepatic steatosis in high-fat-fed mice.
American journal of physiology. Gastrointestinal and liver physiology.
2007 Jun; 292(6):G1671-82. doi:
10.1152/ajpgi.00523.2006
. [PMID: 17322064] - S D Proctor, S E Kelly, K L Stanhope, P J Havel, J C Russell. Synergistic effects of conjugated linoleic acid and chromium picolinate improve vascular function and renal pathophysiology in the insulin-resistant JCR:LA-cp rat.
Diabetes, obesity & metabolism.
2007 Jan; 9(1):87-95. doi:
10.1111/j.1463-1326.2006.00578.x
. [PMID: 17199723] - Khelifa Arab, Adrien Rossary, Laurent Soulère, Jean-Paul Steghens. Conjugated linoleic acid, unlike other unsaturated fatty acids, strongly induces glutathione synthesis without any lipoperoxidation.
The British journal of nutrition.
2006 Nov; 96(5):811-9. doi:
10.1017/bjn20061910
. [PMID: 17092368] - Arunabh Bhattacharya, M Mizanur Rahman, Roger McCarter, Marianne O'Shea, Gabriel Fernandes. Conjugated linoleic acid and chromium lower body weight and visceral fat mass in high-fat-diet-fed mice.
Lipids.
2006 May; 41(5):437-44. doi:
10.1007/s11745-006-5117-3
. [PMID: 16933788] - Craig D Albright, Erich Klem, Anish A Shah, Patricia Gallagher. Breast cancer cell-targeted oxidative stress: enhancement of cancer cell uptake of conjugated linoleic acid, activation of p53, and inhibition of proliferation.
Experimental and molecular pathology.
2005 Oct; 79(2):118-25. doi:
10.1016/j.yexmp.2005.05.005
. [PMID: 15992797] - Karine Valeille, Jacqueline Férézou, Ghislaine Amsler, Annie Quignard-Boulangé, Michel Parquet, Daniel Gripois, Victoria Dorovska-Taran, Jean-Charles Martin. A cis-9,trans-11-conjugated linoleic acid-rich oil reduces the outcome of atherogenic process in hyperlipidemic hamster.
American journal of physiology. Heart and circulatory physiology.
2005 Aug; 289(2):H652-9. doi:
10.1152/ajpheart.00130.2005
. [PMID: 15778275] - Yumiko Yasui, Masashi Hosokawa, Takehiko Sahara, Rikako Suzuki, Satoru Ohgiya, Hiroyuki Kohno, Takuji Tanaka, Kazuo Miyashita. Bitter gourd seed fatty acid rich in 9c,11t,13t-conjugated linolenic acid induces apoptosis and up-regulates the GADD45, p53 and PPARgamma in human colon cancer Caco-2 cells.
Prostaglandins, leukotrienes, and essential fatty acids.
2005 Aug; 73(2):113-9. doi:
10.1016/j.plefa.2005.04.013
. [PMID: 15961301] - Alan A Sneddon, Hsin-Chieh Wu, Andrew Farquharson, Ian Grant, John R Arthur, Dino Rotondo, Sun-Nam Choe, Klaus W J Wahle. Regulation of selenoprotein GPx4 expression and activity in human endothelial cells by fatty acids, cytokines and antioxidants.
Atherosclerosis.
2003 Nov; 171(1):57-65. doi:
10.1016/j.atherosclerosis.2003.08.008
. [PMID: 14642406]