imidazolidine (BioDeep_00001873006)

   


代谢物信息卡片


imidazolidine

化学式: C3H8N2 (72.0687448)
中文名称: 咪唑啉
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1CNCN1
InChI: InChI=1S/C3H8N2/c1-2-5-3-4-1/h4-5H,1-3H2

描述信息

同义名列表

1 个代谢物同义名

imidazolidine



数据库引用编号

4 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Qing-Tian Ji, De-Kun Hu, Xian-Fu Mu, Xiao-Xue Tian, Li Zhou, Si Yao, Xiao-Hui Wang, Shu-Zhen Xiang, Hao-Jie Ye, Li-Jun Fan, Pei-Yi Wang. Cucurbit[7]uril-Mediated Supramolecular Bactericidal Nanoparticles: Their Assembly Process, Controlled Release, and Safe Treatment of Intractable Plant Bacterial Diseases. Nano letters. 2022 06; 22(12):4839-4847. doi: 10.1021/acs.nanolett.2c01203. [PMID: 35667033]
  • Haigen Nie, Zhen Wei, Xin-Long Ni, Yu Liu. Assembly and Applications of Macrocyclic-Confinement-Derived Supramolecular Organic Luminescent Emissions from Cucurbiturils. Chemical reviews. 2022 05; 122(9):9032-9077. doi: 10.1021/acs.chemrev.1c01050. [PMID: 35312308]
  • Jaroslav Pejchal, Petr Jošt, Lubica Múčková, Rudolf Andrýs, Miroslav Lísa, Jana Zdarova Karasova. A systematic evaluation of the cucurbit[7]uril pharmacokinetics and toxicity after a single dose and short-term repeated administration in mice. Archives of toxicology. 2022 05; 96(5):1411-1421. doi: 10.1007/s00204-022-03249-7. [PMID: 35220471]
  • Nasima Arshad, Muhammad Ismail Mir, Fouzia Perveen, Aneela Javed, Memona Javaid, Aamer Saeed, Pervaiz Ali Channar, Shahid Iqbal Farooqi, Saad Alkahtani, Jamshed Anwar. Investigations on Anticancer Potentials by DNA Binding and Cytotoxicity Studies for Newly Synthesized and Characterized Imidazolidine and Thiazolidine-Based Isatin Derivatives. Molecules (Basel, Switzerland). 2022 Jan; 27(2):. doi: 10.3390/molecules27020354. [PMID: 35056668]
  • Xin Guo, Pingping Cao, Xiongfeng Lian, Meng Hu, Jingyi Zhao, Wenjing Shen, Haili Wang, Hailong Yu, Yingzhu Chen. The neuroprotective effect of phillyrin in intracerebral hemorrhagic mice is produced by activation of the Nrf2 signaling pathway. European journal of pharmacology. 2021 Oct; 909(?):174439. doi: 10.1016/j.ejphar.2021.174439. [PMID: 34425100]
  • Tao Liang, Junxin Xue, Zefu Yao, Yang Ye, Xinying Yang, Xuben Hou, Hao Fang. Design, synthesis and biological evaluation of 3, 4-disubstituted-imidazolidine-2, 5-dione derivatives as HDAC6 selective inhibitors. European journal of medicinal chemistry. 2021 Oct; 221(?):113526. doi: 10.1016/j.ejmech.2021.113526. [PMID: 33992929]
  • Jinzheng Wang, Du'an Lin, Ming Liu, Han Liu, Pilar Blasco, Zhenquan Sun, Yan Chu Cheung, Sheng Chen, Xuechen Li. Total Synthesis of Mannopeptimycin β via β-Hydroxyenduracididine Ligation. Journal of the American Chemical Society. 2021 08; 143(32):12784-12790. doi: 10.1021/jacs.1c05922. [PMID: 34352177]
  • Tata Sanjay Kanna Sharma, Kuo-Yuan Hwa. Rational design and preparation of copper vanadate anchored on sulfur doped reduced graphene oxide nanocomposite for electrochemical sensing of antiandrogen drug nilutamide using flexible electrodes. Journal of hazardous materials. 2021 05; 410(?):124659. doi: 10.1016/j.jhazmat.2020.124659. [PMID: 33279323]
  • Salwa A Elgebaly, Robert Todd, Donald L Kreutzer, Robert Christenson, Nashwa El-Khazragy, Reem K Arafa, Mostafa A Rabie, Ahmed F Mohamed, Lamiaa A Ahmed, Nesrine S El Sayed. Nourin-Associated miRNAs: Novel Inflammatory Monitoring Markers for Cyclocreatine Phosphate Therapy in Heart Failure. International journal of molecular sciences. 2021 Mar; 22(7):. doi: 10.3390/ijms22073575. [PMID: 33808213]
  • Viraj G Naik, Vikash Kumar, Achikanath C Bhasikuttan, Kavita Kadu, Sutapa Roy Ramanan, Akhil A Bhosle, Mainak Banerjee, Amrita Chatterjee. Solid-Supported Amplification of Aggregation Emission: A Tetraphenylethylene-Cucurbit[6]uril@Hydroxyapatite-Based Supramolecular Sensing Assembly for the Detection of Spermine and Spermidine in Human Urine and Blood. ACS applied bio materials. 2021 02; 4(2):1813-1822. doi: 10.1021/acsabm.0c01527. [PMID: 35014527]
  • Roshan M Borkar, Shankar Gajji, Soheb A Mohammed, Mithul Srivastava, Velma Ganga Reddy, Aishwarya Jala, Shailendra Asthana, Ahmed Kamal, Sanjay K Banerjee, Srinivas Ragampeta. Identification and characterization of in vitro and in vivo fidarestat metabolites: Toxicity and efficacy evaluation of metabolites. Journal of mass spectrometry : JMS. 2021 Feb; 56(2):e4694. doi: 10.1002/jms.4694. [PMID: 33410180]
  • Tao Kang, Shuang Gao, Li-Xia Zhao, Yue Zhai, Fei Ye, Ying Fu. Design, Synthesis, and SAR of Novel 1,3-Disubstituted Imidazolidine or Hexahydropyrimidine Derivatives as Herbicide Safeners. Journal of agricultural and food chemistry. 2021 Jan; 69(1):45-54. doi: 10.1021/acs.jafc.0c04436. [PMID: 33372787]
  • Jonathan A Zweig, Mikah S Brandes, Barbara H Brumbach, Maya Caruso, Kirsten M Wright, Joseph F Quinn, Amala Soumyanath, Nora E Gray. Prolonged Treatment with Centella asiatica Improves Memory, Reduces Amyloid-β Pathology, and Activates NRF2-Regulated Antioxidant Response Pathway in 5xFAD Mice. Journal of Alzheimer's disease : JAD. 2021; 81(4):1453-1468. doi: 10.3233/jad-210271. [PMID: 33935097]
  • Minghui Wang, Ruixuan Gao, Mengmeng Zheng, Peng Sang, Chunpu Li, En Zhang, Qi Li, Jianfeng Cai. Development of Bis-cyclic Imidazolidine-4-one Derivatives as Potent Antibacterial Agents. Journal of medicinal chemistry. 2020 12; 63(24):15591-15602. doi: 10.1021/acs.jmedchem.0c00171. [PMID: 32914977]
  • Federico Martinón-Torres, Sarah Rusch, Dymphy Huntjens, Bart Remmerie, Johan Vingerhoets, Katie McFadyen, Fernando Ferrero, Eugenio Baraldi, Pablo Rojo, Cristina Epalza, Marita Stevens. Pharmacokinetics, Safety, and Antiviral Effects of Multiple Doses of the Respiratory Syncytial Virus (RSV) Fusion Protein Inhibitor, JNJ-53718678, in Infants Hospitalized With RSV Infection: A Randomized Phase 1b Study. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 2020 12; 71(10):e594-e603. doi: 10.1093/cid/ciaa283. [PMID: 32201897]
  • Bart Remmerie, Maarten van den Boer, Thomas Van Looy, Inneke Wynant, Sarah Rusch, Dymphy Huntjens, Marc De Meulder, Marita Stevens. Integrating Duodenal Sampling in a Human Mass Balance Study to Quantify the Elimination Pathways of JNJ-53718678, a Respiratory Syncytial Virus Fusion Protein Inhibitor. Advances in therapy. 2020 01; 37(1):578-591. doi: 10.1007/s12325-019-01162-7. [PMID: 31832988]
  • Kirill Gorshkov, Amy Q Wang, Wei Sun, Ethan Fisher, Marta Frigeni, Marc Singleton, Natasha Thorne, Bradley Class, Wenwei Huang, Nicola Longo, Minh-Ha T Do, Elizabeth A Ottinger, Xin Xu, Wei Zheng. Phosphocyclocreatine is the dominant form of cyclocreatine in control and creatine transporter deficiency patient fibroblasts. Pharmacology research & perspectives. 2019 12; 7(6):e00525. doi: 10.1002/prp2.525. [PMID: 31859463]
  • Thangavelu Kokulnathan, Raj Karthik, Shen-Ming Chen, Jeyaraj Vinoth Kumar, Subramanian Sakthinathan. A cerium vanadate interconnected with a carbon nanofiber heterostructure for electrochemical determination of the prostate cancer drug nilutamide. Mikrochimica acta. 2019 07; 186(8):579. doi: 10.1007/s00604-019-3665-5. [PMID: 31352538]
  • Kumuthini Rajendran, Thangavelu Kokulnathan, Shen-Ming Chen, Joseph Anthuvan Allen, Chinnuswamy Viswanathan, Helen Annal Therese. Nitrogen doped carbon nanofibers loaded with hierarchical vanadium tetrasulfide for the voltammetric detection of the non-steroidal anti-prostate cancer drug nilutamide. Mikrochimica acta. 2019 02; 186(3):141. doi: 10.1007/s00604-019-3251-x. [PMID: 30707311]
  • Rong Wang, Yongzheng Luo, Yadong Lu, Daojuan Wang, Tingyu Wang, Wenyuan Pu, Yong Wang. Maggot Extracts Alleviate Inflammation and Oxidative Stress in Acute Experimental Colitis via the Activation of Nrf2. Oxidative medicine and cellular longevity. 2019; 2019(?):4703253. doi: 10.1155/2019/4703253. [PMID: 31827675]
  • Sara Gutiérrez, María Morón, Mercedes Griera, David Sucunza, Laura Calleros, Andrea García-Jérez, Claire Coderch, Francisco J Hermoso, Carolina Burgos, Manuel Rodríguez-Puyol, Beatriz de Pascual-Teresa, María L Diez-Marques, Antonio Jimenez, Miguel Toro-Londoño, Diego Rodríguez-Puyol, Juan J Vaquero. Discovery of potent calpain inhibitors based on the azolo-imidazolidenone scaffold. European journal of medicinal chemistry. 2018 Sep; 157(?):946-959. doi: 10.1016/j.ejmech.2018.08.045. [PMID: 30165342]
  • Galina A Gazieva, Lada V Anikina, Tatyana V Nechaeva, Sergey A Pukhov, Tatyana B Karpova, Sergey V Popkov, Yulia V Nelyubina, Natalya G Kolotyrkina, Angelina N Kravchenko. Synthesis and biological evaluation of new substituted thioglycolurils, their analogues and derivatives. European journal of medicinal chemistry. 2017 Nov; 140(?):141-154. doi: 10.1016/j.ejmech.2017.09.009. [PMID: 28923382]
  • Dymphy R H Huntjens, Sivi Ouwerkerk-Mahadevan, Anne Brochot, Sarah Rusch, Marita Stevens, Rene Verloes. Population Pharmacokinetic Modeling of JNJ-53718678, a Novel Fusion Inhibitor for the Treatment of Respiratory Syncytial Virus: Results from a Phase I, Double-Blind, Randomized, Placebo-Controlled First-in-Human Study in Healthy Adult Subjects. Clinical pharmacokinetics. 2017 11; 56(11):1331-1342. doi: 10.1007/s40262-017-0522-8. [PMID: 28238203]
  • Himangshu Sonowal, Pabitra B Pal, Jian-Jun Wen, Sanjay Awasthi, Kota V Ramana, Satish K Srivastava. Aldose reductase inhibitor increases doxorubicin-sensitivity of colon cancer cells and decreases cardiotoxicity. Scientific reports. 2017 06; 7(1):3182. doi: 10.1038/s41598-017-03284-w. [PMID: 28600556]
  • Konrad Boblewski, Artur Lehmann, Aleksandra Marchwinska, Anita Kornicka, Aleksandra Wasilewska, Franciszek Saczewski, Apolonia Rybczynska. COMPARISON OF THE EFFECTS OF MARSANIDINE DERIVATIVES ON RAT CARDIOVASCULAR SYSTEM. Acta poloniae pharmaceutica. 2017 Mar; 74(2):579-586. doi: NULL. [PMID: 29624262]
  • R Karthik, R Sasikumar, Shen-Ming Chen, J Vinoth Kumar, A Elangovan, V Muthuraj, P Muthukrishnan, Fahad M A Al-Hemaid, M Ajmal Ali, Mohamed S Elshikh. A highly sensitive and selective electrochemical determination of non-steroidal prostate anti-cancer drug nilutamide based on f-MWCNT in tablet and human blood serum sample. Journal of colloid and interface science. 2017 Feb; 487(?):289-296. doi: 10.1016/j.jcis.2016.10.047. [PMID: 27792936]
  • Kirtikar Shukla, Pabitra Bikash Pal, Himangshu Sonowal, Satish K Srivastava, Kota V Ramana. Aldose Reductase Inhibitor Protects against Hyperglycemic Stress by Activating Nrf2-Dependent Antioxidant Proteins. Journal of diabetes research. 2017; 2017(?):6785852. doi: 10.1155/2017/6785852. [PMID: 28740855]
  • Shigehiko Takegami, Keisuke Kitamura, Mayuko Ohsugi, Atsuko Konishi, Tatsuya Kitade. 19F Nuclear Magnetic Resonance Spectrometric Determination of the Partition Coefficients of Flutamide and Nilutamide (Antiprostate Cancer Drugs) in a Lipid Nano-Emulsion and Prediction of Its Encapsulation Efficiency for the Drugs. AAPS PharmSciTech. 2016 Dec; 17(6):1500-1506. doi: 10.1208/s12249-016-0495-1. [PMID: 26863891]
  • Barbora de Courten, Maximilian Pj de Courten, Georgia Soldatos, Sonia L Dougherty, Nora Straznicky, Markus Schlaich, Karly C Sourris, Vibhasha Chand, Jean Ljm Scheijen, Bronwyn A Kingwell, Mark E Cooper, Casper G Schalkwijk, Karen Z Walker, Josephine M Forbes. Diet low in advanced glycation end products increases insulin sensitivity in healthy overweight individuals: a double-blind, randomized, crossover trial. The American journal of clinical nutrition. 2016 Jun; 103(6):1426-33. doi: 10.3945/ajcn.115.125427. [PMID: 27030534]
  • T C Bessegato, M Niehues, G A Buqui, N P Lopes, I R Pitta, S L Galdino, T Dalla Costa. Development and validation of a UHPLC-MS/MS bioanalytical method to quantify in plasma the analgesic candidate PT-31 following a preliminary pharmacokinetic study in rats. Biomedical chromatography : BMC. 2016 Jun; 30(6):852-6. doi: 10.1002/bmc.3618. [PMID: 26379109]
  • Partha Mukhopadhyay, Marc Baggelaar, Katalin Erdelyi, Zongxian Cao, Resat Cinar, Filomena Fezza, Bogna Ignatowska-Janlowska, Jenny Wilkerson, Noortje van Gils, Thomas Hansen, Marc Ruben, Marjolein Soethoudt, Laura Heitman, George Kunos, Mauro Maccarrone, Aron Lichtman, Pál Pacher, Mario Van der Stelt. The novel, orally available and peripherally restricted selective cannabinoid CB2 receptor agonist LEI-101 prevents cisplatin-induced nephrotoxicity. British journal of pharmacology. 2016 Feb; 173(3):446-58. doi: 10.1111/bph.13338. [PMID: 26398481]
  • Kyoko Nitta, Sen Shi, Takako Nagai, Megumi Kanasaki, Munehiro Kitada, Swayam Prakash Srivastava, Masakazu Haneda, Keizo Kanasaki, Daisuke Koya. Oral Administration of N-Acetyl-seryl-aspartyl-lysyl-proline Ameliorates Kidney Disease in Both Type 1 and Type 2 Diabetic Mice via a Therapeutic Regimen. BioMed research international. 2016; 2016(?):9172157. doi: 10.1155/2016/9172157. [PMID: 27088094]
  • Fei Ding, Wei Peng. Biological assessment of neonicotinoids imidacloprid and its major metabolites for potentially human health using globular proteins as a model. Journal of photochemistry and photobiology. B, Biology. 2015 Jun; 147(?):24-36. doi: 10.1016/j.jphotobiol.2015.03.010. [PMID: 25837412]
  • Roshan M Borkar, Murali Mohan Bhandi, Ajay P Dubey, Prajwal P Nandekar, Abhay T Sangamwar, Sanjay K Banerjee, R Srinivas. Plasma protein binding, pharmacokinetics, tissue distribution and CYP450 biotransformation studies of fidarestat by ultra high performance liquid chromatography-high resolution mass spectrometry. Journal of pharmaceutical and biomedical analysis. 2015 Jan; 102(?):386-99. doi: 10.1016/j.jpba.2014.10.008. [PMID: 25459938]
  • Saumya Pandey. Aldose Reductase Inhibitor Fidarestat as a Promising Drug Targeting Autophagy in Colorectal Carcinoma: a Pilot Study. Asian Pacific journal of cancer prevention : APJCP. 2015; 16(12):4981-5. doi: 10.7314/apjcp.2015.16.12.4981. [PMID: 26163626]
  • Matthew C O'Reilly, Thomas H Oguin, Sarah A Scott, Paul G Thomas, Charles W Locuson, Ryan D Morrison, J Scott Daniels, H Alex Brown, Craig W Lindsley. Discovery of a highly selective PLD2 inhibitor (ML395): a new probe with improved physiochemical properties and broad-spectrum antiviral activity against influenza strains. ChemMedChem. 2014 Dec; 9(12):2633-7. doi: 10.1002/cmdc.201402333. [PMID: 25210004]
  • Veeresham Ciddi, Dilip Dodda. Therapeutic potential of resveratrol in diabetic complications: In vitro and in vivo studies. Pharmacological reports : PR. 2014 Oct; 66(5):799-803. doi: 10.1016/j.pharep.2014.04.006. [PMID: 25149983]
  • Takashi Yokota, Hirofumi Tomita, Yasuhiro Mori, Takeshi Kudo, Hitoshi Hiraga, Naoyuki Suto, Takumi Higuma, Naoki Abe, Hiroyuki Hanada, Tomohiro Osanai, Ken Okumura. Imidapril and enalapril similarly inhibit plasma matrix metalloproteinase activities and attenuate left ventricular remodeling in patients with acute myocardial infarction. Journal of cardiovascular pharmacology. 2014 Jun; 63(6):528-32. doi: 10.1097/fjc.0000000000000077. [PMID: 24709636]
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