2-[[2-(4-Hydroxyphenyl)ethylamino]methyl]-3,4-dihydro-2H-naphthalen-1-one (BioDeep_00001872312)

   


代谢物信息卡片


2-[[2-(4-Hydroxyphenyl)ethylamino]methyl]-3,4-dihydro-2H-naphthalen-1-one

化学式: C19H21NO2 (295.1572206)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1CC2=CC=CC=C2C(=O)C1CNCCC3=CC=C(C=C3)O
InChI: InChI=1S/C19H21NO2/c21-17-9-5-14(6-10-17)11-12-20-13-16-8-7-15-3-1-2-4-18(15)19(16)22/h1-6,9-10,16,20-21H,7-8,11-13H2

描述信息

D018377 - Neurotransmitter Agents > D018663 - Adrenergic Agents > D018674 - Adrenergic Antagonists

同义名列表

1 个代谢物同义名

2-[[2-(4-Hydroxyphenyl)ethylamino]methyl]-3,4-dihydro-2H-naphthalen-1-one



数据库引用编号

4 个数据库交叉引用编号

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代谢反应

0 个相关的代谢反应过程信息。

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在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Shoshiro Okada, Naoko Yamaguchi. Alpha1-adrenoceptor activation is involved in the central N-methyl-D-aspartate-induced adrenomedullary outflow in rats. European journal of pharmacology. 2010 Aug; 640(1-3):55-62. doi: 10.1016/j.ejphar.2010.04.038. [PMID: 20450908]
  • Kerstin Buck, Boris Ferger. The selective alpha1 adrenoceptor antagonist HEAT reduces L-DOPA-induced dyskinesia in a rat model of Parkinson's disease. Synapse (New York, N.Y.). 2010 Feb; 64(2):117-26. doi: 10.1002/syn.20709. [PMID: 19771592]
  • Liaoyuan A Hu, Tian Zhou, Jinwoo Ahn, Shuli Wang, Julia Zhou, Yi Hu, Qingyun Liu. Human and mouse trace amine-associated receptor 1 have distinct pharmacology towards endogenous monoamines and imidazoline receptor ligands. The Biochemical journal. 2009 Oct; 424(1):39-45. doi: 10.1042/bj20090998. [PMID: 19725810]
  • Y Y Zhang, K M Xu, C Han. Alpha(1)-adrenoceptor subtypes mediating inotropic responses in rat heart. The Journal of pharmacology and experimental therapeutics. 1999 Nov; 291(2):829-36. doi: NULL. [PMID: 10525106]
  • Y Y Zhang, Z Z Lu, H Wei, Q D Han. [Sertindole, a novel alpha 1A-adrenoceptor selective antagonist]. Yao xue xue bao = Acta pharmaceutica Sinica. 1997 Jul; 32(7):490-5. doi: . [PMID: 11596272]
  • V K Pabbathi, H Brennan, A Muxworthy, L Gill, F E Holmes, M Vignes, L W Haynes. Catecholaminergic regulation of proliferation and survival in rat forebrain paraventricular germinal cells. Brain research. 1997 Jun; 760(1-2):22-33. doi: 10.1016/s0006-8993(97)00272-2. [PMID: 9237514]
  • T A Esbenshade, A Hirasawa, G Tsujimoto, T Tanaka, J Yano, K P Minneman, T J Murphy. Cloning of the human alpha 1d-adrenergic receptor and inducible expression of three human subtypes in SK-N-MC cells. Molecular pharmacology. 1995 May; 47(5):977-85. doi: NULL. [PMID: 7746284]
  • K P Minneman, T L Theroux, S Hollinger, C Han, T A Esbenshade. Selectivity of agonists for cloned alpha 1-adrenergic receptor subtypes. Molecular pharmacology. 1994 Nov; 46(5):929-36. doi: . [PMID: 7969082]
  • K M Wilson, S Gilchrist, K P Minneman. Comparison of alpha 1-adrenergic receptor-stimulated inositol phosphate formation in primary neuronal and glial cultures. Journal of neurochemistry. 1990 Aug; 55(2):691-7. doi: 10.1111/j.1471-4159.1990.tb04188.x. [PMID: 1973457]
  • Y Matsushima, S Akabane, M Kawamura, K Ito. Distribution of alpha 1- and alpha 2-adrenoceptors in brush border and basolateral membranes from rat kidney cortical tubules. Japanese journal of pharmacology. 1987 Oct; 45(2):284-7. doi: 10.1254/jjp.45.284. [PMID: 2830424]
  • C Han, P W Abel, K P Minneman. Heterogeneity of alpha 1-adrenergic receptors revealed by chlorethylclonidine. Molecular pharmacology. 1987 Oct; 32(4):505-10. doi: NULL. [PMID: 2890094]
  • Y Matsushima, S Akabane, K Ito. Characterization of alpha 1- and alpha 2-adrenoceptors directly associated with basolateral membranes from rat kidney proximal tubules. Biochemical pharmacology. 1986 Aug; 35(15):2593-600. doi: 10.1016/0006-2952(86)90058-4. [PMID: 2874810]
  • D Sugden, M A Namboodiri, D C Klein, J E Pierce, R Grady, I N Mefford. Ovine pineal alpha 1-adrenoceptors: characterization and evidence for a functional role in the regulation of serum melatonin. Endocrinology. 1985 May; 116(5):1960-7. doi: 10.1210/endo-116-5-1960. [PMID: 2985366]
  • E Schlicker, O E Brodde, M Göthert, M Schaperdoth. Increased affinity and preference of halogenated derivatives of BE 2254 for alpha 1-adrenoceptors demonstrated by functional and binding experiments. Journal of cardiovascular pharmacology. 1984 Nov; 6(6):1238-44. doi: 10.1097/00005344-198411000-00035. [PMID: 6084785]
  • H Glossmann, F Lübbecke. [125I]-HEAT:fifty percent of the ligand can bind to the alpha1-adrenoceptors with extremely high affinity. Naunyn-Schmiedeberg's archives of pharmacology. 1982 Oct; 321(1):7-10. doi: 10.1007/bf00586341. [PMID: 6292742]
  • A Adams, B Jarrott. Development of a radioiodinated ligand for characterising alpha 1-adrenoceptors. Life sciences. 1982 Mar; 30(11):945-52. doi: 10.1016/0024-3205(82)90623-3. [PMID: 6280000]
  • H Huland, H P Leichtweiss, H J Augustin. Effect of angiotensin II antagonist, alpha-receptor blockage, and denervation on blood flow reduction in experimental, chronic hydronephrosis. Investigative urology. 1980 Nov; 18(3):203-6. doi: NULL. [PMID: 6107280]