N-Oleoylglycine (BioDeep_00001871922)

Main id: BioDeep_00000027053

 

PANOMIX_OTCML-2023


代谢物信息卡片


N-Oleoylglycine

化学式: C20H37NO3 (339.27732920000005)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CCCCCCCCC=CCCCCCCCC(=O)NCC(=O)O
InChI: InChI=1S/C20H37NO3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-19(22)21-18-20(23)24/h9-10H,2-8,11-18H2,1H3,(H,21,22)(H,23,24)/b10-9-

描述信息

A fatty acid derivative that is the 9Z-octadecenoyl derivative of glycine. It is believed to be an intermediate in oleamide biosynthesis.
N-Oleoyl glycine is a lipoamino acid, which stimulates adipogenesis associated with activation of CB1 receptor and Akt signaling pathway in 3T3-L1 adipocyte.
N-Oleoyl glycine is a lipoamino acid, which stimulates adipogenesis associated with activation of CB1 receptor and Akt signaling pathway in 3T3-L1 adipocyte.

同义名列表

2 个代谢物同义名

N-Oleoylglycine; N-Oleoyl glycine



数据库引用编号

6 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Julia T Tanzo, Veronica L Li, Amanda L Wiggenhorn, Maria Dolores Moya-Garzon, Wei Wei, Xuchao Lyu, Wentao Dong, Usman A Tahir, Zsu-Zsu Chen, Daniel E Cruz, Shuliang Deng, Xu Shi, Shuning Zheng, Yan Guo, Mario Sims, Monther Abu-Remaileh, James G Wilson, Robert E Gerszten, Jonathan Z Long, Mark D Benson. CYP4F2 is a human-specific determinant of circulating N-acyl amino acid levels. The Journal of biological chemistry. 2023 Apr; ?(?):104764. doi: 10.1016/j.jbc.2023.104764. [PMID: 37121548]
  • Casey I Gallagher, Diba Sheipouri, Susan Shimmon, Tristan Rawling, Robert J Vandenberg. Identification of N-acyl amino acids that are positive allosteric modulators of glycine receptors. Biochemical pharmacology. 2020 10; 180(?):114117. doi: 10.1016/j.bcp.2020.114117. [PMID: 32579961]
  • Giulia Donvito, Fabiana Piscitelli, Pretal Muldoon, Asti Jackson, Rosa Maria Vitale, Enrico D'Aniello, Catia Giordano, Bogna M Ignatowska-Jankowska, Mohammed A Mustafa, Francesca Guida, Gavin N Petrie, Linda Parker, Reem Smoum, Laura Sim-Selley, Sabatino Maione, Aron H Lichtman, M Imad Damaj, Vincenzo Di Marzo, Raphael Mechoulam. N-Oleoyl-glycine reduces nicotine reward and withdrawal in mice. Neuropharmacology. 2019 04; 148(?):320-331. doi: 10.1016/j.neuropharm.2018.03.020. [PMID: 29567093]
  • Shannon N Mostyn, Tristan Rawling, Sarasa Mohammadi, Susan Shimmon, Zachary J Frangos, Subhodeep Sarker, Arsalan Yousuf, Irina Vetter, Renae M Ryan, Macdonald J Christie, Robert J Vandenberg. Development of an N-Acyl Amino Acid That Selectively Inhibits the Glycine Transporter 2 To Produce Analgesia in a Rat Model of Chronic Pain. Journal of medicinal chemistry. 2019 03; 62(5):2466-2484. doi: 10.1021/acs.jmedchem.8b01775. [PMID: 30714733]
  • Songbo Wang, Qi Xu, Gang Shu, Lina Wang, Ping Gao, Qianyun Xi, Yongliang Zhang, Qingyan Jiang, Xiaotong Zhu. N-Oleoyl glycine, a lipoamino acid, stimulates adipogenesis associated with activation of CB1 receptor and Akt signaling pathway in 3T3-L1 adipocyte. Biochemical and biophysical research communications. 2015 Oct; 466(3):438-43. doi: 10.1016/j.bbrc.2015.09.046. [PMID: 26365347]
  • Shalini Chaturvedi, William J Driscoll, Brenda M Elliot, Martha M Faraday, Neil E Grunberg, Gregory P Mueller. In vivo evidence that N-oleoylglycine acts independently of its conversion to oleamide. Prostaglandins & other lipid mediators. 2006 Dec; 81(3-4):136-49. doi: 10.1016/j.prostaglandins.2006.09.001. [PMID: 17085322]