pseudoephedrine hydrochloride (BioDeep_00001871641)
代谢物信息卡片
pseudoephedrine hydrochloride
化学式: C10H15NO.HCl (201.09203559999997)
中文名称: 盐酸伪麻黄碱
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC(C(C1=CC=CC=C1)O)NC.Cl
InChI: /m0./s1
描述信息
D019141 - Respiratory System Agents > D018927 - Anti-Asthmatic Agents > D001993 - Bronchodilator Agents
C78272 - Agent Affecting Nervous System > C29747 - Adrenergic Agent > C87053 - Adrenergic Agonist
D018373 - Peripheral Nervous System Agents > D001337 - Autonomic Agents
A hydrochloride that is the monohydrochloride salt of pseudoephedrine.
D019141 - Respiratory System Agents > D014663 - Nasal Decongestants
D002317 - Cardiovascular Agents > D014662 - Vasoconstrictor Agents
同义名列表
1 个代谢物同义名
数据库引用编号
7 个数据库交叉引用编号
- ChEBI: CHEBI:8604
- KEGGdrug: D00485
- PubChem: 9581
- ChEMBL: CHEMBL1200724
- MeSH: Pseudoephedrine
- CAS: 345-78-8
- MetaboLights: MTBLC8604
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Jiatai Yin, Yiheng Gou, Yiheng Wang, Qingyuan Ma, Rui Wang, Jing Yu, Yajun Zhang, Jing Wang, Qian Li, Xinfeng Zhao. Can the heptapeptide ASSIVSF of the β2-adrenoceptor recognize ephedrine and pseudoephedrine epimers in a complex system?.
Journal of chromatography. A.
2024 May; 1722(?):464857. doi:
10.1016/j.chroma.2024.464857. [PMID: 38569445] - Celestine Nwabu Ekweogu, Emmanuel Iroha Akubugwo, Okezie Emmanuel, Chidi Ijeoma Nosiri, Mercylyn Ezinne Uche, Oluwapelumi Eniola Adurosakin, Solomon Nnah Ijioma, Eziuche Amadike Ugbogu. Phytochemical profiling, toxicity studies, wound healing, analgesic and anti-inflammatory activities of Musa paradisiaca L. Musaceae (Plantain) stem extract in rats.
Journal of ethnopharmacology.
2024 Mar; 322(?):117639. doi:
10.1016/j.jep.2023.117639. [PMID: 38135229] - Yue-Chiun Li, Chia-Hung Wu, Thi Ha Le, Qingjun Yuan, Luqi Huang, Guo-Fen Chen, Mei-Lin Yang, Sio-Hong Lam, Hsin-Yi Hung, Handong Sun, Yi-Hung Wu, Ping-Chung Kuo, Tian-Shung Wu. A Modified 1H-NMR Quantification Method of Ephedrine Alkaloids in Ephedrae Herba Samples.
International journal of molecular sciences.
2023 Jul; 24(14):. doi:
10.3390/ijms241411272. [PMID: 37511036] - Nikolaos Rousis, Richard Bade, Iván Romero-Sánchez, Jochen F Mueller, Nikolaos S Thomaidis, Kevin V Thomas, Emma Gracia-Lor. Festivals following the easing of COVID-19 restrictions: Prevalence of new psychoactive substances and illicit drugs.
Environment international.
2023 Jun; 178(?):108075. doi:
10.1016/j.envint.2023.108075. [PMID: 37399770] - Qingge Zheng, Xiangyu Mu, Shaobin Pan, Ruqiao Luan, Pan Zhao. Ephedrae herba: A comprehensive review of its traditional uses, phytochemistry, pharmacology, and toxicology.
Journal of ethnopharmacology.
2023 May; 307(?):116153. doi:
10.1016/j.jep.2023.116153. [PMID: 36641108] - Mitsuhiko Nose, Risa Kobayashi, Momoka Tada, Shinsuke Hisaka, Sayaka Masada, Masato Homma, Takashi Hakamatsuka. Comparison of ephedrine and pseudoephedrine contents in 34 Kampo extracts containing Ephedrae Herba used clinically in Japan.
Journal of natural medicines.
2023 Mar; ?(?):. doi:
10.1007/s11418-023-01687-w. [PMID: 36854954] - Yoshitomi Kudo, Hirokazu Ando, Ai Kaneda, Honoka Ito, Kazuki Umemoto, Si-Ran Ni, Masayuki Mikage, Yohei Sasaki. Evaluation of rooting characteristics of Ephedra cuttings by anatomy and promising strain selection based on rooting characteristics and alkaloid content.
Journal of natural medicines.
2023 Mar; 77(2):327-342. doi:
10.1007/s11418-023-01680-3. [PMID: 36680565] - Xuedan Huang, Sumiko Hyuga, Yoshiaki Amakura, Masashi Hyuga, Nahoko Uchiyama, Takashi Hakamatsuka, Yukihiro Goda, Hiroshi Odaguchi, Toshihiko Hanawa, Yoshinori Kobayashi. Overlooked switch from transient sedation to sustained excitement in the Biphasic effects of Ephedra Herb extract administered orally to mice.
Journal of ethnopharmacology.
2023 Jan; 301(?):115827. doi:
10.1016/j.jep.2022.115827. [PMID: 36240977] - Hajime Hiyama, Yosuke Yoshioka, Ryo Ohsawa. Evaluation of the Influence of Genetic and Environmental Factors on the Ephedrine Alkaloids Content of Ephedra sinica.
Biological & pharmaceutical bulletin.
2023; 46(12):1692-1698. doi:
10.1248/bpb.b23-00374. [PMID: 38044092] - Longfei Guo, Ping He, Yuan He, Yu Gao, Xiaoting Zhang, Tongtong Huo, Cheng Peng, Fanyun Meng. Predicting the comprehensive geospatial pattern of two ephedrine-type alkaloids for Ephedra sinica in Inner Mongolia.
PloS one.
2023; 18(4):e0283967. doi:
10.1371/journal.pone.0283967. [PMID: 37083689] - Mengnan Lu, Yongjuan Zhang, Shiyan Wang, Xiaona Wang, Shengnan Zhang, Ji De. Ephedrine and pseudoephedrine in Ephedra saxatilis on the vertical altitude gradient changed in southern Tibet Plateau, China.
PloS one.
2023; 18(8):e0290696. doi:
10.1371/journal.pone.0290696. [PMID: 37624827] - Shingen Misaka, Yuko Ono, R Verena Taudte, Eva Hoier, Hiroshi Ogata, Tomoyuki Ono, Jörg König, Hiroshi Watanabe, Martin F Fromm, Kenju Shimomura. Exposure of Fexofenadine, but Not Pseudoephedrine, Is Markedly Decreased by Green Tea Extract in Healthy Volunteers.
Clinical pharmacology and therapeutics.
2022 09; 112(3):627-634. doi:
10.1002/cpt.2682. [PMID: 35678032] - Yang Fu, PeiPei Yuan, Yajuan Zheng, Liyuan Gao, Yaxin Wei, Yi Chen, Panying Li, Yuan Ruan, Xiaoke Zheng, Weisheng Feng. Ephedra herb reduces adriamycin-induced testicular toxicity by upregulating the gonadotropin-releasing hormone signalling pathway.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
2022 Jun; 150(?):113061. doi:
10.1016/j.biopha.2022.113061. [PMID: 35658231] - Chunying Song, Dongping Yu, Gaowa Jin, Junjie Ding, Han Zhou, Zhimou Guo, Xinmiao Liang. High-performance liquid chromatography quantitative analysis of ephedrine alkaloids in Ephedrae Herba on a perfluorooctyl stationary phase.
Journal of separation science.
2022 Mar; 45(5):1051-1058. doi:
10.1002/jssc.202100645. [PMID: 34984820] - Sooyoung Lee, Wang-Seob Shim, Heejo Yoo, Sanghee Choi, Jiyoung Yoon, Kwang-Young Lee, Eun-Kyoung Chung, Byung-Cheol Lee, Sung-Vin Yim, Bo-Hyung Kim, Kyung-Tae Lee. A Pharmacokinetic Study of Ephedrine and Pseudoephedrine after Oral Administration of Ojeok-San by Validated LC-MS/MS Method in Human Plasma.
Molecules (Basel, Switzerland).
2021 Nov; 26(22):. doi:
10.3390/molecules26226991. [PMID: 34834083] - Shaopeng Yu, Yao Chen, Yusen Xiang, He Lin, Mengge Wang, Wenbo Ye, Pei Zhang, Hongzhuan Chen, Guoqiang Lin, Yuying Zhu, Lili Chen, Jiange Zhang. Pseudoephedrine and its derivatives antagonize wild and mutated severe acute respiratory syndrome-CoV-2 viruses through blocking virus invasion and antiinflammatory effect.
Phytotherapy research : PTR.
2021 Oct; 35(10):5847-5860. doi:
10.1002/ptr.7245. [PMID: 34472141] - Jeong Sun Sohn, Jin-Seok Choi. Development and evaluation of pseudoephedrine hydrochloride abuse-deterrent formulations using thermal modified rice starch.
International journal of biological macromolecules.
2021 Jul; 182(?):1248-1258. doi:
10.1016/j.ijbiomac.2021.05.055. [PMID: 33992650] - Hiroyuki Fuchino, Osamu Iida, Noriaki Kawano, Nobuo Kawahara, Kayo Yoshimatsu. One-pot discriminant LC/MS quantitative analysis of ephedrine and pseudoephedrine using Finger Masher and their distribution in the aerial stems of Ephedra plants.
Journal of natural medicines.
2021 Jun; 75(3):707-716. doi:
10.1007/s11418-021-01494-1. [PMID: 33599897] - Olga Guselnikova, Hyunsoo Lim, Jongbeom Na, Miharu Eguchi, Hyun-Jong Kim, Roman Elashnikov, Pavel Postnikov, Vaclav Svorcik, Oleg Semyonov, Elena Miliutina, Oleksiy Lyutakov, Yusuke Yamauchi. Enantioselective SERS sensing of pseudoephedrine in blood plasma biomatrix by hierarchical mesoporous Au films coated with a homochiral MOF.
Biosensors & bioelectronics.
2021 May; 180(?):113109. doi:
10.1016/j.bios.2021.113109. [PMID: 33677356] - Hsin-Yi Hung, Shih-Min Lin, Chia-Ying Li, Sio-Hong Lam, Yu-Yi Chan, Meei-Jen Liou, Po-Chuen Shieh, Fu-An Chen, Ping-Chung Kuo, Tian-Shung Wu. A Rapid and Feasible 1H-NMR Quantification Method of Ephedrine Alkaloids in Ephedra Herbal Preparations.
Molecules (Basel, Switzerland).
2021 Mar; 26(6):. doi:
10.3390/molecules26061599. [PMID: 33805790] - Hajime Hiyama, Aya Ozawa, Bunsho Makino, Yosuke Yoshioka, Ryo Ohsawa. Stability and Reproducibility of Ephedra sinica Ephedrine Alkaloid Content and Terrestrial Stem Dry Weight.
Biological & pharmaceutical bulletin.
2021; 44(11):1781-1789. doi:
10.1248/bpb.b21-00599. [PMID: 34719654] - Jonathan Q Tran, Peijin Zhang, Susan Walker, Atalanta Ghosh, Mary Syto, Xiaomin Wang, Sarah Harris, Maria Palmisano. Multiple-Dose Pharmacokinetics of Ozanimod and its Major Active Metabolites and the Pharmacodynamic and Pharmacokinetic Interactions with Pseudoephedrine, a Sympathomimetic Agent, in Healthy Subjects.
Advances in therapy.
2020 12; 37(12):4944-4958. doi:
10.1007/s12325-020-01500-0. [PMID: 33025342] - Xiaolei Chen, Jiacheng Lin, Qingsong Liang, Xiaoyin Chen, Zhongping Wu. Pseudoephedrine alleviates atopic dermatitis-like inflammatory responses in vivo and in vitro.
Life sciences.
2020 Oct; 258(?):118139. doi:
10.1016/j.lfs.2020.118139. [PMID: 32721463] - Salvatore Febbraro, Tim Shea, Ana Santos Cravo. Bioavailability of Triprolidine as a Single Agent or in Combination With Pseudoephedrine: A Randomized, Open-Label Crossover Study in Healthy Volunteers.
Clinical pharmacology in drug development.
2020 05; 9(4):486-495. doi:
10.1002/cpdd.777. [PMID: 32133778] - Ziyaur Rahman, Mohammad S Aqueel, Maxwell Korang-Yeboah, Ahmed S Zidan, Jia Chen, Alaadin Y Alayoubi, Celia N Cruz, Muhammad Ashraf. Evaluation of commercially available meth-deterrent pseudoephedrine hydrochloride products.
International journal of pharmaceutics.
2020 Feb; 575(?):118909. doi:
10.1016/j.ijpharm.2019.118909. [PMID: 31811923] - Małgorzata Łabańska, Patrycja Ciosek-Skibińska, Wojciech Wróblewski. Critical Evaluation of Laboratory Potentiometric Electronic Tongues for Pharmaceutical Analysis-An Overview.
Sensors (Basel, Switzerland).
2019 Dec; 19(24):. doi:
10.3390/s19245376. [PMID: 31817537] - M Volpp, U Holzgrabe. Determination of plasma protein binding for sympathomimetic drugs by means of ultrafiltration.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.
2019 Jan; 127(?):175-184. doi:
10.1016/j.ejps.2018.10.027. [PMID: 30391401] - Hiroaki Hayashi, Musavvara Shukurova, Shihoko Oikawa, Minami Ohta, Isao Fujii, Firuza Nasyrova, Kurbon Aliev, Hikmat Hisoriev, Inoyat Fattokhov, Madibron Saidov. Field Survey of Ephedra Plants in Central Asia (1). Characterization of Ephedra equisetina, Ephedra intermedia, and Their Putative Hybrids Collected in the Zaravshan Mountains of Tajikistan.
Biological & pharmaceutical bulletin.
2019; 42(4):552-560. doi:
10.1248/bpb.b18-00289. [PMID: 30930415] - Shunsuke Nakamori, Jun Takahashi, Sumiko Hyuga, Jinwei Yang, Hiroaki Takemoto, Takuro Maruyama, Naohiro Oshima, Nahoko Uchiyama, Yoshiaki Amakura, Masashi Hyuga, Takashi Hakamatsuka, Yukihiro Goda, Hiroshi Odaguchi, Toshihiko Hanawa, Yoshinori Kobayashi. Analgesic Effects of Ephedra Herb Extract, Ephedrine Alkaloids-Free Ephedra Herb Extract, Ephedrine, and Pseudoephedrine on Formalin-Induced Pain.
Biological & pharmaceutical bulletin.
2019; 42(9):1538-1544. doi:
10.1248/bpb.b19-00260. [PMID: 31474713] - Jeremy S Morris, Ryan A Groves, Jillian M Hagel, Peter J Facchini. An N-methyltransferase from Ephedra sinica catalyzing the formation of ephedrine and pseudoephedrine enables microbial phenylalkylamine production.
The Journal of biological chemistry.
2018 08; 293(35):13364-13376. doi:
10.1074/jbc.ra118.004067. [PMID: 29929980] - Cuimei Liu, Peipei Liu, Wei Jia, Yingfeng Fan. Carbon and Nitrogen Stable Isotope Analyses of Ephedra Plant and Ephedrine Samples and Their Application For Methamphetamine Profiling.
Journal of forensic sciences.
2018 Jul; 63(4):1053-1058. doi:
10.1111/1556-4029.13692. [PMID: 29193073] - Shuhua Deng, Wencan Huang, Xiaojia Ni, Ming Zhang, Haoyang Lu, Zhanzhang Wang, Jinqing Hu, Xiuqing Zhu, Chang Qiu, Dewei Shang, Yuefeng Zhang, Linghui Xiong, Yuguan Wen. Pharmacokinetics of guaifenesin, pseudoephedrine and hydrocodone in a combination oral liquid formulation, administered as single and multiple doses in healthy Chinese volunteers, and comparison with data for individual compounds formulated as Antuss®.
Xenobiotica; the fate of foreign compounds in biological systems.
2017 Oct; 47(10):870-878. doi:
10.1080/00498254.2016.1241451. [PMID: 27662264] - O Shoshany, N Abhyankar, J Elyaguov, C Niederberger. Efficacy of treatment with pseudoephedrine in men with retrograde ejaculation.
Andrology.
2017 07; 5(4):744-748. doi:
10.1111/andr.12361. [PMID: 28380686] - Jia-Yu Tong, Jung Chao, Yun-Tao Dai, Zi-Quan Fan, Dan-Dan Wang, Xue-Mei Qin, Shi-Lin Chen. [Establish quality evaluation system for standard Ephedrae Herba decoction].
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.
2017 Mar; 42(5):823-829. doi:
10.19540/j.cnki.cjcmm.20170121.011. [PMID: 28994520] - Hajime Hiyama, Aya Ozawa, Hiroaki Kumazawa, Osami Takeda. Stabilization of Ephedrine Alkaloid Content in Ephedra sinica by Selective Breeding and Stolon Propagation.
Biological & pharmaceutical bulletin.
2017; 40(1):43-48. doi:
10.1248/bpb.b16-00531. [PMID: 28049947] - Eun Sook Jeong, Ki Hun Kim, Eunju Cha, Oh-Seung Kwon, Sangwon Cha, Jaeick Lee. Direct and rapid quantitation of ephedrines in human urine by paper spray ionization/high resolution mass spectrometry.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2016 Aug; 1028(?):237-241. doi:
10.1016/j.jchromb.2016.06.040. [PMID: 27393909] - Nehal Fayek Farid, Eglal A Abdelaleem. HPTLC Method for the Determination of Paracetamol, Pseudoephedrine and Loratidine in Tablets and Human Plasma.
Journal of chromatographic science.
2016 Apr; 54(4):647-52. doi:
10.1093/chromsci/bmv184. [PMID: 26762956] - Hui Kong, Huihua Qu, Baoping Qu, Wenhao Zeng, Yan Zhao, Xueqian Wang, Qingguo Wang. Correlation between the transdermal characteristics of pseudoephedrine and amygdalin in majiepingchuan in vitro.
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan.
2016 Apr; 36(2):238-42. doi:
10.1016/s0254-6272(16)30033-4. [PMID: 27400480] - Arezou Taghvimi, Hamed Hamishehkar, Mahmoud Ebrahimi. Magnetic nano graphene oxide as solid phase extraction adsorbent coupled with liquid chromatography to determine pseudoephedrine in urine samples.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2016 Jan; 1009-1010(?):66-72. doi:
10.1016/j.jchromb.2015.12.005. [PMID: 26708626] - Afsal Mohammed Kadavilpparampu, Haider A J Al-Lawati, FakhrEldin O Suliman, Salma M Z Al Kindy. Determination of the pseudoephedrine content in pharmaceutical formulations and in biological fluids using a microbore HPLC system interfaced to a microfluidic chemiluminescence detector.
Luminescence : the journal of biological and chemical luminescence.
2015 Dec; 30(8):1242-9. doi:
10.1002/bio.2887. [PMID: 25773865] - J G Pallarés, Á López-Samanes, V E Fernández-Elías, R Aguado-Jiménez, J F Ortega, C Gómez, R Ventura, J Segura, R Mora-Rodríguez. Pseudoephedrine and circadian rhythm interaction on neuromuscular performance.
Scandinavian journal of medicine & science in sports.
2015 Dec; 25(6):e603-12. doi:
10.1111/sms.12385. [PMID: 25515692] - Mengying Lv, Jianbo Sun, Min Wang, Wanqiu Huang, Hongyan Fan, Fengguo Xu, Zunjian Zhang. GC-MS based metabolomics study of stems and roots of Ephedra sinica.
Journal of pharmaceutical and biomedical analysis.
2015 Oct; 114(?):49-52. doi:
10.1016/j.jpba.2015.04.035. [PMID: 26004227] - Mengying Lv, Jiaqing Chen, Yiqiao Gao, Jianbo Sun, Qianqian Zhang, Mohan Zhang, Fengguo Xu, Zunjian Zhang. Metabolomics based on liquid chromatography with mass spectrometry reveals the chemical difference in the stems and roots derived from Ephedra sinica.
Journal of separation science.
2015 Oct; 38(19):3331-6. doi:
10.1002/jssc.201500529. [PMID: 26224607] - Kai Luo, Yajuan Li, Xiaohui Zheng, Zhenghua Song. Pharmacokinetic of pseudoephedrine in rat serum with luminol-pepsin chemiluminescence system by flow injection analysis.
Applied biochemistry and biotechnology.
2015 Feb; 175(4):1805-16. doi:
10.1007/s12010-014-1396-y. [PMID: 25427591] - Shuai Song, Qingfa Tang, Huiling Huo, Hancheng Li, Xuefeng Xing, Jiabo Luo. Simultaneous quantification and pharmacokinetics of alkaloids in Herba Ephedrae-Radix Aconiti Lateralis extracts.
Journal of analytical toxicology.
2015 Jan; 39(1):58-68. doi:
10.1093/jat/bku113. [PMID: 25324527] - Masashi Matsumoto, Manabu Hirayama, Norihiro Ohtomi, Takeshi Ohno, Yukihiro Nomura, Osamu Iida, Koji Sugimura, Nobuo Kawahara, Takashi Tsuchida, Masayuki Mikage. Influence of genetic factors on the ephedrine alkaloid composition ratio of Ephedra plants.
Journal of natural medicines.
2015 Jan; 69(1):63-7. doi:
10.1007/s11418-014-0863-7. [PMID: 25115226] - Kellie R Pritchard-Peschek, David G Jenkins, Mark A Osborne, Gary J Slater, Dennis R Taaffe. The dose-response relationship between pseudoephedrine ingestion and exercise performance.
Journal of science and medicine in sport.
2014 Sep; 17(5):531-4. doi:
10.1016/j.jsams.2013.07.015. [PMID: 23988786] - Jheng-Jie Jiang, Chon-Lin Lee, Meng-Der Fang. Emerging organic contaminants in coastal waters: anthropogenic impact, environmental release and ecological risk.
Marine pollution bulletin.
2014 Aug; 85(2):391-9. doi:
10.1016/j.marpolbul.2013.12.045. [PMID: 24439316] - Daniel Jolley, Brian Dawson, Shane K Maloney, James White, Carmel Goodman, Peter Peeling. Hydration and urinary pseudoephedrine levels after a simulated team game.
International journal of sport nutrition and exercise metabolism.
2014 Jun; 24(3):325-32. doi:
10.1123/ijsnem.2013-0076. [PMID: 24458099] - Dongli Deng, Hao Deng, Lichun Zhang, Yingying Su. Determination of ephedrine and pseudoephedrine by field-amplified sample injection capillary electrophoresis.
Journal of chromatographic science.
2014 Apr; 52(4):357-62. doi:
10.1093/chromsci/bmt039. [PMID: 23619557] - Zhongping Wu, Xiangliang Kong, Tong Zhang, Jin Ye, Zhaoqin Fang, Xuejun Yang. Pseudoephedrine/ephedrine shows potent anti-inflammatory activity against TNF-α-mediated acute liver failure induced by lipopolysaccharide/D-galactosamine.
European journal of pharmacology.
2014 Feb; 724(?):112-21. doi:
10.1016/j.ejphar.2013.11.032. [PMID: 24365491] - Arlan L Rosenbloom. Sudden death of a young woman attributed to diabetic ketoacidosis.
Journal of forensic and legal medicine.
2013 Nov; 20(8):1063-5. doi:
10.1016/j.jflm.2013.09.028. [PMID: 24237820] - C-J Hwang, M-H Park, H-W Jung, Y-K Park, Y-H Kim, J-S Kang, C-W Cho. A stable fixed-dose combination tablet of pseudoephedrine and KOB extracts for the extended release.
Drug research.
2013 Nov; 63(11):572-8. doi:
10.1055/s-0033-1348222. [PMID: 23780499] - Yu Lin, Yanye Zou, Jialiang Lin, Tao Zhang, Jie Deng. Comparative single-dose pharmacokinetics of rasagiline in minipigs after oral dosing or transdermal administration via a newly developed patch.
Xenobiotica; the fate of foreign compounds in biological systems.
2013 Aug; 43(8):705-10. doi:
10.3109/00498254.2012.758396. [PMID: 23339547] - Kellie R Pritchard-Peschek, Mark A Osborne, Gary J Slater, Dennis R Taaffe, David G Jenkins. Pseudoephedrine and preexercise feeding: influence on performance.
Medicine and science in sports and exercise.
2013 Jun; 45(6):1152-7. doi:
10.1249/mss.0b013e3182808e23. [PMID: 23274597] - Nengsheng Ye, Jian Li, Yali Xie, Chang Liu. Graphene oxide coated capillary for chiral separation by CE.
Electrophoresis.
2013 Mar; 34(6):841-5. doi:
10.1002/elps.201200516. [PMID: 23307565] - A K Tang, W K Tang, H J Liang, F Chan, S C Mak, G S Ungvari. Clinical characteristics of cough mixture abusers referred to three substance abuse clinics in Hong Kong: a retrospective study.
East Asian archives of psychiatry : official journal of the Hong Kong College of Psychiatrists = Dong Ya jing shen ke xue zhi : Xianggang jing shen ke yi xue yuan qi kan.
2012 Dec; 22(4):154-9. doi:
NULL. [PMID: 23271584] - Colton H F Wong, Emmie N M Ho, W H Kwok, David K K Leung, Gary N W Leung, Francis P W Tang, April S Y Wong, Jenny K Y Wong, Nola H Yu, Terence S M Wan. Interconversion of ephedrine and pseudoephedrine during chemical derivatization.
Drug testing and analysis.
2012 Dec; 4(12):1028-33. doi:
10.1002/dta.1384. [PMID: 22733708] - J-C He, E-F Feng, M Liu, H-L Li, M Tian, Q Zhang, L-C Dong, G-L Xu. Development and Validation of a Liquid Chromatography-tandem Mass Spectrometry Method for the Simultaneous Determination of Acrivastine and Pseudoephedrine in Human Plasma and its Application in Pharmacokinetics.
Arzneimittel-Forschung.
2012 Oct; 62(10):e3. doi:
10.1055/s-0032-1329594. [PMID: 23047471] - J-C He, E-F Feng, M Liu, H-L Li, M Tian, Q Zhang, L-C Dong, G-L Xu. Development and validation of a liquid chromatography-tandem mass spectrometry method for the simultaneous determination of acrivastine and pseudoephedrine in human plasma and its application in pharmacokinetics.
Arzneimittel-Forschung.
2012 Oct; 62(10):449-56. doi:
10.1055/s-0032-1314877. [PMID: 22936420] - Jillian M Hagel, Raz Krizevski, Frédéric Marsolais, Efraim Lewinsohn, Peter J Facchini. Biosynthesis of amphetamine analogs in plants.
Trends in plant science.
2012 Jul; 17(7):404-12. doi:
10.1016/j.tplants.2012.03.004. [PMID: 22502775] - Osquel Barroso, Danielle Goudreault, Marcel-lí Carbó Banús, Christiane Ayotte, Irene Mazzoni, Thierry Boghosian, Olivier Rabin. Determination of urinary concentrations of pseudoephedrine and cathine after therapeutic administration of pseudoephedrine-containing medications to healthy subjects: implications for doping control analysis of these stimulants banned in sport.
Drug testing and analysis.
2012 May; 4(5):320-9. doi:
10.1002/dta.291. [PMID: 21548139] - Toshiaki Nagai, Akira Kurosu, Kazumi Matsushima, Junko Maeda, Atsushi Tohei, Shinobu Yamauchi, Masahito Hitosugi, Shogo Tokudome. Simultaneous identification of the enantiomers and diastereomers of N,O-di-trifluoroacetylated ephedrine and norephedrine in blood plasma using chiral capillary gas chromatography-mass spectrometry with selected ion monitoring.
Journal of analytical toxicology.
2012 Mar; 36(2):96-105. doi:
10.1093/jat/bkr010. [PMID: 22337778] - Dong-Li Deng, Ji-You Zhang, Chen Chen, Xiao-Ling Hou, Ying-Ying Su, Lan Wu. Monolithic molecular imprinted polymer fiber for recognition and solid phase microextraction of ephedrine and pseudoephedrine in biological samples prior to capillary electrophoresis analysis.
Journal of chromatography. A.
2012 Jan; 1219(?):195-200. doi:
10.1016/j.chroma.2011.11.016. [PMID: 22138227] - Jae Kuk Ryu, Sun Dong Yoo. Simultaneous determination of levocetirizine and pseudoephedrine in dog plasma by liquid chromatography-mass spectrometry in the presence of dextrocetirizine.
Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques.
2012; 15(4):519-27. doi:
10.18433/j39c76. [PMID: 23106955] - Stephen D Cooper, Brenda L Fletcher, Melanie A Rehder Silinski, Sherri S Brown, Jon W Lodge, Reshan A Fernando, Bradley J Collins. Determination of L-ephedrine, pseudoephedrine, and caffeine in rat plasma by liquid chromatography-tandem mass spectrometry.
Journal of analytical toxicology.
2011 Jul; 35(6):341-8. doi:
10.1093/anatox/35.6.341. [PMID: 21740690] - Li-ping Yu, Xiao-ke Wang, Jia-bo Luo. [Determination of ephedrine hydrochloride, pseudoephedrine hydrochloride and methylephedrine hydrochloride in maxingshigan decoction by CE].
Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials.
2011 Apr; 34(4):620-3. doi:
". [PMID: 21809550] - Detlev Belder, Kamal Tolba, Stefan Nagl. Rapid quantitative determination of ephedra alkaloids in tablet formulations and human urine by microchip electrophoresis.
Electrophoresis.
2011 Feb; 32(3-4):440-7. doi:
10.1002/elps.201000476. [PMID: 21254134] - Jin-Ki Kim, Jun-Pil Jee, Jeong-Sook Park, Hyung Tae Kim, Chong-Kook Kim. Reverse-phase liquid chromatography with electrospray ionization/mass spectrometry for the quantification of pseudoephedrine in human plasma and application to a bioequivalence study.
Arzneimittel-Forschung.
2011; 61(5):276-81. doi:
10.1055/s-0031-1296199. [PMID: 21755810] - Xuan Chen, Xiaohong Bai, Xiao Wang, Jing Wang, Wei Bu. [Analysis of the preferred conformations and determination of the concentrations of ephedrine and pseudoephedrine based on hollow fiber liquid-phase microextraction].
Se pu = Chinese journal of chromatography.
2010 Dec; 28(12):1144-9. doi:
NULL. [PMID: 21438366] - Myung-Jae Lee, Heon-Woo Lee, Jong-Min Kang, Ji-Hyung Seo, Seong-Kun Tak, Wangseob Shim, Sung-Vin Yim, Seung Jae Hong, Kyung-Tae Lee. Application of a rapid and selective method for the simultaneous determination of carebastine and pseudoephedrine in human plasma by liquid chromatography-electrospray mass spectrometry for bioequivalence study in Korean subjects.
Biomedical chromatography : BMC.
2010 Oct; 24(10):1031-7. doi:
10.1002/bmc.1392. [PMID: 20099369] - Sabina Strano-Rossi, Daniele Leone, Xavier de la Torre, Francesco Botrè. Analysis of stimulants in oral fluid and urine by gas chromatography-mass spectrometry II: pseudophedrine.
Journal of analytical toxicology.
2010 May; 34(4):210-5. doi:
10.1093/jat/34.4.210. [PMID: 20465867] - Jairam R Palamanda, Hong Mei, Richard Morrison, Robbie L McLeod, Kevin McCormick, Michel Corboz, Xiaoying Xu, Walter Korfmacher, Lisa Broske, Amin A Nomeir. Pharmacokinetics of pseudoephedrine in rats, dogs, monkeys and its pharmacokinetic-pharmacodynamic relationship in a feline model of nasal congestion.
Drug metabolism letters.
2010 Apr; 4(2):56-61. doi:
10.2174/187231210791292762. [PMID: 20446910] - Mario Thevis, Gerd Sigmund, Hans Geyer, Wilhelm Schänzer. Stimulants and doping in sport.
Endocrinology and metabolism clinics of North America.
2010 Mar; 39(1):89-105, ix. doi:
10.1016/j.ecl.2009.10.011. [PMID: 20122452] - Hong-Gang Lou, Hong Yuan, Zou-Rong Ruan, Bo Jiang. Simultaneous determination of paracetamol, pseudoephedrine, dextrophan and chlorpheniramine in human plasma by liquid chromatography-tandem mass spectrometry.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2010 Mar; 878(7-8):682-8. doi:
10.1016/j.jchromb.2010.01.005. [PMID: 20133213] - Hao Li, Chao Zhang, Jiang Wang, Yao Jiang, J Paul Fawcett, Jingkai Gu. Simultaneous quantitation of paracetamol, caffeine, pseudoephedrine, chlorpheniramine and cloperastine in human plasma by liquid chromatography-tandem mass spectrometry.
Journal of pharmaceutical and biomedical analysis.
2010 Feb; 51(3):716-22. doi:
10.1016/j.jpba.2009.10.009. [PMID: 19879084] - Josh Gunn, Scott Kriger, Andrea R Terrell. Identification and quantitation of amphetamine, methamphetamine, MDMA, pseudoephedrine, and ephedrine in blood, plasma, and serum using gas chromatography-mass spectrometry (GC/MS).
Methods in molecular biology (Clifton, N.J.).
2010; 603(?):37-43. doi:
10.1007/978-1-60761-459-3_4. [PMID: 20077057] - Li-Li Wang, Nobuko Kakiuchi, Masayuki Mikage. Studies of Ephedra plants in Asia. Part 6: Geographical changes of anatomical features and alkaloids content of Ephedra sinica.
Journal of natural medicines.
2010 Jan; 64(1):63-9. doi:
10.1007/s11418-009-0374-0. [PMID: 20091241] - Michael Moawad, Cheang S Khoo, Samiuela Lee, James R Hennell. Simultaneous determination of eight sympathomimetic amines in urine by gas chromatography/mass spectrometry.
Journal of AOAC International.
2010 Jan; 93(1):116-22. doi:
. [PMID: 20334173] - Ashok K Shakya, Tawfiq A Arafat, Ahmad N Abuawwad, Munther Melhim, Jafar Al-Ghani, Mahmoud J Yacoub. Simultaneous determination of triprolidine and pseudoephedrine in human plasma by liquid chromatography-ion trap mass spectrometry.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2009 Dec; 877(32):4071-8. doi:
10.1016/j.jchromb.2009.10.021. [PMID: 19926351] - Yan-Ming Liu, Wei Tian, Yu-Xiu Jia, Hai-Yan Yue. Simultaneous determination of methylephedrine and pseudoephedrine in human urine by CE with electrochemiluminescence detection and its application to pharmacokeinetics.
Biomedical chromatography : BMC.
2009 Nov; 23(11):1138-44. doi:
10.1002/bmc.1235. [PMID: 19492345] - Jie Lü, Xiang Jin, Pei-Hong Mao, Xiang-Dong Ma, Hai-Qiu Ling, Yong-Hong Fan, Long Yu, Bao-Shan Wu, Ping-Kai Ouyang. Transfer of Ephedra genomic DNA to yeasts by ion implantation.
Applied biochemistry and biotechnology.
2009 Sep; 158(3):571-81. doi:
10.1007/s12010-009-8597-9. [PMID: 19280123] - A Pokrywka, W Tszyrsznic, D J Kwiatkowska. Problems of the use of pseudoephedrine by athletes.
International journal of sports medicine.
2009 Aug; 30(8):569-72. doi:
10.1055/s-0029-1202826. [PMID: 19382058] - Sabina Strano-Rossi, Daniele Leone, Xavier de la Torre, Francesco Botrè. The relevance of the urinary concentration of ephedrines in anti-doping analysis: determination of pseudoephedrine, cathine, and ephedrine after administration of over-the-counter medicaments.
Therapeutic drug monitoring.
2009 Aug; 31(4):520-6. doi:
10.1097/ftd.0b013e3181ac6006. [PMID: 19571776] - K Deventer, P Van Eenoo, G Baele, O J Pozo, W Van Thuyne, F T Delbeke. Interpretation of urinary concentrations of pseudoephedrine and its metabolite cathine in relation to doping control.
Drug testing and analysis.
2009 May; 1(5):209-13. doi:
10.1002/dta.31. [PMID: 20355197] - Ling Wang, Fang Feng, Xue Quan Wang, Lan Zhu. Influences of urinary pH on the pharmacokinetics of three amphetamine-type stimulants using a new high-performance liquid chromatographic method.
Journal of pharmaceutical sciences.
2009 Feb; 98(2):728-38. doi:
10.1002/jps.21438. [PMID: 18481797] - Wei Zhao, An-Jun Deng, Guan-Hua Du, Jin-Lan Zhang, Zhi-Hong Li, Hai-Lin Qin. Chemical constituents of the stems of Ephedra sinica.
Journal of Asian natural products research.
2009; 11(2):168-71. doi:
10.1080/10286020802573552. [PMID: 19219730] - G Hendriks, D R A Uges, J P Franke. New practical algorithm for modelling analyte recovery in bioanalytical reversed phase and mixed-mode solid phase extraction.
Journal of pharmaceutical and biomedical analysis.
2008 Sep; 48(1):158-70. doi:
10.1016/j.jpba.2008.05.005. [PMID: 18579329] - ". Elimination of exemptions for chemical mixtures containing the list I chemicals ephedrine and/or pseudoephedrine. Final rule.
Federal register.
2008 Jul; 73(133):39611-4. doi:
". [PMID: 18850676] - Tracy L Ranieri, Laura A Ciolino. Rapid selective screening and determination of ephedrine alkaloids using GC-MS footnote mark.
Phytochemical analysis : PCA.
2008 Mar; 19(2):127-35. doi:
10.1002/pca.1025. [PMID: 17879230] - Bridget A Burke, Robert W Lewis, Barbara A Latenser, Joseph Y Chung, Clark Willoughby. Pseudoephedrine legislation decreases methamphetamine laboratory-related burns.
Journal of burn care & research : official publication of the American Burn Association.
2008 Jan; 29(1):138-40. doi:
10.1097/bcr.0b013e31815f2b7a. [PMID: 18182911] - M A Brandenburg, S J Brown, W L Arneson, D L Arneson. The association of pseudoephedrine sales restrictions on emergency department urine drug screen results in Oklahoma.
The Journal of the Oklahoma State Medical Association.
2007 Nov; 100(11):436-9. doi:
NULL. [PMID: 18183861] - Omnia A Ismaiel, Matthew S Halquist, Magda Y Elmamly, Abdalla Shalaby, H Thomas Karnes. Monitoring phospholipids for assessment of matrix effects in a liquid chromatography-tandem mass spectrometry method for hydrocodone and pseudoephedrine in human plasma.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2007 Nov; 859(1):84-93. doi:
10.1016/j.jchromb.2007.09.007. [PMID: 17936695] - Pei-Hong Mao, Xiang-Dong Ma, Xiang Jin, Hong-Mei Yang, Kai Lou. [Production of l-ephedrine and d-pseudoephedrine in recombined yeasts obtained by argon ion implantation mediated Ephedra genome DNA transformation].
Wei sheng wu xue bao = Acta microbiologica Sinica.
2007 Oct; 47(5):905-9. doi:
". [PMID: 18062271]