N-(2-hydroxyoctadecanoyl)-hydroxysphinganine (BioDeep_00001871612)
代谢物信息卡片
化学式: C36H73NO5 (599.5488448)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CCCCCCCCCCCCCCCCC(C(=O)NC(CO)C(C(CCCCCCCCCCCCCC)O)O)O
InChI: InChI=1S/C36H73NO5/c1-3-5-7-9-11-13-15-17-18-20-22-24-26-28-30-34(40)36(42)37-32(31-38)35(41)33(39)29-27-25-23-21-19-16-14-12-10-8-6-4-2/h32-35,38-41H,3-31H2,1-2H3,(H,37,42)/t32-,33+,34?,35-/m0/s1
相关代谢途径
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代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
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0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Yoshihiro Tokudome. Influence of Oral Administration of Lactic Acid Bacteria Metabolites on Skin Barrier Function and Water Content in a Murine Model of Atopic Dermatitis.
Nutrients.
2018 Dec; 10(12):. doi:
10.3390/nu10121858. [PMID: 30513743] - Andrej Kováčik, Michaela Šilarová, Petra Pullmannová, Jaroslav Maixner, Kateřina Vávrová. Effects of 6-Hydroxyceramides on the Thermotropic Phase Behavior and Permeability of Model Skin Lipid Membranes.
Langmuir : the ACS journal of surfaces and colloids.
2017 03; 33(11):2890-2899. doi:
10.1021/acs.langmuir.7b00184. [PMID: 28230380] - Min-Bin Chen, Qin Jiang, Yuan-yuan Liu, Yan Zhang, Bang-shun He, Mu-Xin Wei, Jian-Wei Lu, Yong Ji, Pei-Hua Lu. C6 ceramide dramatically increases vincristine sensitivity both in vivo and in vitro, involving AMP-activated protein kinase-p53 signaling.
Carcinogenesis.
2015 Sep; 36(9):1061-70. doi:
10.1093/carcin/bgv094. [PMID: 26116623] - Henrike Peuschel, Ulrich Sydlik, Susanne Grether-Beck, Ingo Felsner, Daniel Stöckmann, Sascha Jakob, Matthias Kroker, Judith Haendeler, Marijan Gotić, Christiane Bieschke, Jean Krutmann, Klaus Unfried. Carbon nanoparticles induce ceramide- and lipid raft-dependent signalling in lung epithelial cells: a target for a preventive strategy against environmentally-induced lung inflammation.
Particle and fibre toxicology.
2012 Dec; 9(?):48. doi:
10.1186/1743-8977-9-48. [PMID: 23228165] - Yixing Jiang, Nicole A DiVittore, James M Kaiser, Sriram S Shanmugavelandy, Jennifer L Fritz, Yasser Heakal, Hephzibah Rani S Tagaram, Hua Cheng, Myles C Cabot, Kevin F Staveley-O'Carroll, Melissa A Tran, Todd E Fox, Brian M Barth, Mark Kester. Combinatorial therapies improve the therapeutic efficacy of nanoliposomal ceramide for pancreatic cancer.
Cancer biology & therapy.
2011 Oct; 12(7):574-85. doi:
10.4161/cbt.12.7.15971. [PMID: 21795855] - Jacqueline V Chapman, Valérie Gouazé-Andersson, Myles C Cabot. Expression of P-glycoprotein in HeLa cells confers resistance to ceramide cytotoxicity.
International journal of oncology.
2010 Dec; 37(6):1591-7. doi:
10.3892/ijo_00000813. [PMID: 21042729] - Natalia Yu Ryabova, M A Kiselev, S Dante, T Hauss, A M Balagurov. Investigation of stratum corneum lipid model membranes with free fatty acid composition by neutron diffraction.
European biophysics journal : EBJ.
2010 Jul; 39(8):1167-76. doi:
10.1007/s00249-009-0569-z. [PMID: 20012954] - Philipp A Lang, Ortraud Beringer, Jan P Nicolay, Oliver Amon, Daniela S Kempe, Tobias Hermle, Philipp Attanasio, Ahmad Akel, Richard Schäfer, Björn Friedrich, Teut Risler, Matthias Baur, Christoph J Olbricht, Lothar Bernd Zimmerhackl, Peter F Zipfel, Thomas Wieder, Florian Lang. Suicidal death of erythrocytes in recurrent hemolytic uremic syndrome.
Journal of molecular medicine (Berlin, Germany).
2006 May; 84(5):378-88. doi:
10.1007/s00109-006-0058-0. [PMID: 16622713]