Lintitript (BioDeep_00001871528)

   


代谢物信息卡片


SR 27897(Lintitript)

化学式: C20H14ClN3O3S (411.0444364000001)
中文名称: 2-[[[4-(2-氯苯基)-2-噻唑基]氨基]羰基]-1H-吲哚-1-乙酸
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1=CC=C2C(=C1)C=C(N2CC(=O)O)C(=O)NC3=NC(=CS3)C4=CC=CC=C4Cl
InChI: InChI=1S/C20H14ClN3O3S/c21-14-7-3-2-6-13(14)15-11-28-20(22-15)23-19(27)17-9-12-5-1-4-8-16(12)24(17)10-18(25)26/h1-9,11H,10H2,(H,25,26)(H,22,23,27)

描述信息

D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006727 - Hormone Antagonists
D006133 - Growth Substances > D010937 - Plant Growth Regulators > D007210 - Indoleacetic Acids
C147908 - Hormone Therapy Agent > C547 - Hormone Antagonist

同义名列表

2 个代谢物同义名

SR 27897(Lintitript); Lintitript



数据库引用编号

5 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Wenda Wu, Hui-Ren Zhou, Kaiyu He, Xiao Pan, Yoshiko Sugita-Konishi, Maiko Watanabe, Haibin Zhang, James J Pestka. Role of cholecystokinin in anorexia induction following oral exposure to the 8-ketotrichothecenes deoxynivalenol, 15-acetyldeoxynivalenol, 3-acetyldeoxynivalenol, fusarenon X, and nivalenol. Toxicological sciences : an official journal of the Society of Toxicology. 2014 Apr; 138(2):278-89. doi: 10.1093/toxsci/kft335. [PMID: 24385417]
  • V Cano, B Merino, L Ezquerra, B Somoza, M Ruiz-Gayo. A cholecystokinin-1 receptor agonist (CCK-8) mediates increased permeability of brain barriers to leptin. British journal of pharmacology. 2008 Jul; 154(5):1009-15. doi: 10.1038/bjp.2008.149. [PMID: 18587446]
  • Elodie Archer-Lahlou, Irina Tikhonova, Chantal Escrieut, Marlène Dufresne, Catherine Seva, Lucien Pradayrol, Luis Moroder, Bernard Maigret, Daniel Fourmy. Modeled structure of a G-protein-coupled receptor: the cholecystokinin-1 receptor. Journal of medicinal chemistry. 2005 Jan; 48(1):180-91. doi: 10.1021/jm049886y. [PMID: 15634012]
  • Victoria Cano, Laura Ezquerra, M Pilar Ramos, Mariano Ruiz-Gayo. Regulation of leptin distribution between plasma and cerebrospinal fluid by cholecystokinin receptors. British journal of pharmacology. 2003 Oct; 140(4):647-52. doi: 10.1038/sj.bjp.0705477. [PMID: 14534148]
  • M Ruiz-Gayo, M M Garrido, J A Fuentes. Inhibition of the hypothalamic-pituitary-adrenal axis in food-deprived rats by a CCK-A receptor antagonist. British journal of pharmacology. 2000 Mar; 129(5):839-42. doi: 10.1038/sj.bjp.0703117. [PMID: 10696079]
  • P Gouldson, P Legoux, C Carillon, X Dumont, G Le Fur, P Ferrara, D Shire. Essential role of extracellular charged residues of the human CCK(1) receptor for interactions with SR 146131, SR 27897 and CCK-8S. European journal of pharmacology. 2000 Feb; 389(2-3):115-24. doi: 10.1016/s0014-2999(99)00894-8. [PMID: 10688974]
  • C Kreiss, W Schwizer, J Borovicka, J B Jansen, C Bouloux, R Pignol, A Bischof Delaloye, M Fried. Effect of lintitript, a new CCK-A receptor antagonist, on gastric emptying of a solid-liquid meal in humans. Regulatory peptides. 1998 Jun; 74(2-3):143-9. doi: 10.1016/s0167-0115(98)00035-4. [PMID: 9712175]
  • H Nakane, M Yoshida, T Murakami. Assessment of the clinical usefulness of serum ribonuclease assays: an indicator for the detection of pancreatic cancer. Gastroenterologia Japonica. 1979; 14(1):55-62. doi: 10.1007/bf02774605. [PMID: 446987]