3,4-Dichloroisocoumarin (BioDeep_00001871525)

   


代谢物信息卡片


3,4-Dichloro-isocoumarin

化学式: C9H4Cl2O2 (213.95883440000003)
中文名称: 3,4-二氯-2-苯并吡喃-1-酮
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1=CC=C2C(=C1)C(=C(OC2=O)Cl)Cl
InChI: InChI=1S/C9H4Cl2O2/c10-7-5-3-1-2-4-6(5)9(12)13-8(7)11/h1-4H

描述信息

D004791 - Enzyme Inhibitors > D011480 - Protease Inhibitors > D015842 - Serine Proteinase Inhibitors

同义名列表

2 个代谢物同义名

3,4-Dichloro-isocoumarin; 3,4-Dichloroisocoumarin



数据库引用编号

5 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome. Cell reports. 2021 04; 35(4):109040. doi: 10.1016/j.celrep.2021.109040. [PMID: 33910017]
  • Brenda H Welter, Heather A Walters, Lesly A Temesvari. Reduced expression of a rhomboid protease, EhROM1, correlates with changes in the submembrane distribution and size of the Gal/GalNAc lectin subunits in the human protozoan parasite, Entamoeba histolytica. PloS one. 2020; 15(3):e0219870. doi: 10.1371/journal.pone.0219870. [PMID: 32134930]
  • Anders P Hakansson, Hazeline Roche-Hakansson, Ann-Kristin Mossberg, Catharina Svanborg. Apoptosis-like death in bacteria induced by HAMLET, a human milk lipid-protein complex. PloS one. 2011 Mar; 6(3):e17717. doi: 10.1371/journal.pone.0017717. [PMID: 21423701]
  • Harry S Courtney, Henry J Pownall. The structure and function of serum opacity factor: a unique streptococcal virulence determinant that targets high-density lipoproteins. Journal of biomedicine & biotechnology. 2010; 2010(?):956071. doi: 10.1155/2010/956071. [PMID: 20671930]
  • Therese Bredholt, Elizabeth Ao Dimba, Hanne R Hagland, Line Wergeland, Jørn Skavland, Kjell O Fossan, Karl J Tronstad, Anne C Johannessen, Olav K Vintermyr, Bjørn T Gjertsen. Camptothecin and khat (Catha edulis Forsk.) induced distinct cell death phenotypes involving modulation of c-FLIPL, Mcl-1, procaspase-8 and mitochondrial function in acute myeloid leukemia cell lines. Molecular cancer. 2009 Nov; 8(?):101. doi: 10.1186/1476-4598-8-101. [PMID: 19912650]
  • J Hou, D R Clemmons, S Smeekens. Expression and characterization of a serine protease that preferentially cleaves insulin-like growth factor binding protein-5. Journal of cellular biochemistry. 2005 Feb; 94(3):470-84. doi: 10.1002/jcb.20328. [PMID: 15534875]
  • Fabiola Parussini, Mayra García, Juan Mucci, Fernán Agüero, Daniel Sánchez, Ulf Hellman, Lena Aslund, Juan José Cazzulo. Characterization of a lysosomal serine carboxypeptidase from Trypanosoma cruzi. Molecular and biochemical parasitology. 2003 Sep; 131(1):11-23. doi: 10.1016/s0166-6851(03)00175-0. [PMID: 12967708]
  • Maryse Laloi, James McCarthy, Olivia Morandi, Christof Gysler, Peter Bucheli. Molecular and biochemical characterisation of two aspartic proteinases TcAP1 and TcAP2 from Theobroma cacao seeds. Planta. 2002 Sep; 215(5):754-62. doi: 10.1007/s00425-002-0818-1. [PMID: 12244440]
  • Irina V Balyasnikova, Eric H Karran, Ronald F Albrecht, Sergei M Danilov. Epitope-specific antibody-induced cleavage of angiotensin-converting enzyme from the cell surface. The Biochemical journal. 2002 Mar; 362(Pt 3):585-95. doi: 10.1042/0264-6021:3620585. [PMID: 11879185]
  • Michèle Brillard-Bourdet, Sophie Réhault, Luiz Juliano, Michèle Ferrer, Thierry Moreau, Francis Gauthier. Amidolytic activity of prostatic acid phosphatase on human semenogelins and semenogelin-derived synthetic substrates. European journal of biochemistry. 2002 Jan; 269(1):390-5. doi: 10.1046/j.0014-2956.2001.02667.x. [PMID: 11784334]
  • N Petrovic, C Grove, P E Langton, N L Misso, P J Thompson. A simple assay for a human serum phospholipase A2 that is associated with high-density lipoproteins. Journal of lipid research. 2001 Oct; 42(10):1706-13. doi: 10.1016/s0022-2275(20)32226-4. [PMID: 11590228]
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