Benzenebutanamine (BioDeep_00001871520)
代谢物信息卡片
4-Phenylbutylamine
化学式: C10H15N (149.1204)
中文名称: 4-苯基丁胺
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1=CC=C(C=C1)CCCCN
InChI: InChI=1S/C10H15N/c11-9-5-4-8-10-6-2-1-3-7-10/h1-3,6-7H,4-5,8-9,11H2
数据库引用编号
5 个数据库交叉引用编号
- ChEBI: CHEBI:44814
- PubChem: 83242
- DrugBank: DB04311
- ChEMBL: CHEMBL79512
- CAS: 13214-66-9
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
| 亚细胞结构定位 | 关联基因列表 |
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文献列表
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Poultry science.
2024 Jan; 103(3):103466. doi:
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Chemical biology & drug design.
2024 Jan; 103(1):e14433. doi:
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Current medical science.
2023 Dec; 43(6):1116-1132. doi:
10.1007/s11596-023-2781-y. [PMID: 38079053] - Yuanbin Li, Hui Lin, Hao Tang, Ke Zhu, Zhangfu Zhou, Zhaohui Zeng, Bin Pan, Zhuang Chen. The STING-IRF3 Signaling Pathway, Mediated by Endoplasmic Reticulum Stress, Contributes to Impaired Myocardial Autophagic Flux After Ischemia/Reperfusion.
Journal of cardiovascular pharmacology.
2023 Nov; 82(5):389-399. doi:
10.1097/fjc.0000000000001465. [PMID: 37851150] - Rui Li, Fan Li, Xuning Wang, Mingxin Bai, Hu Fu, Zhengli Yan, Xiaoping Yang, Yongfei Zhu. 4-Phenylbutyric acid may prevent mouse ovarian and uterine damage due to procymidone-induced alteration of circRNA Scar and circZc3h4 levels by controlling excessive unfolded protein response.
Pesticide biochemistry and physiology.
2023 Nov; 196(?):105631. doi:
10.1016/j.pestbp.2023.105631. [PMID: 37945263] - Xiaocheng Huang, Shanghong Ji, Chenchen Bian, Jian Sun, Hong Ji. The endoplasmic reticulum stress and B cell lymphoma-2 related ovarian killer participate in docosahexaenoic acid-induced adipocyte apoptosis in grass carp (Ctenopharyngodon idellus).
Journal of animal science.
2023 Jan; 101(?):. doi:
10.1093/jas/skad101. [PMID: 37067261] - Xudong Liu, Chao Yang, P Chen, Lei Zhang, Yi Cao. The uses of transcriptomics and lipidomics indicated that direct contact with graphene oxide altered lipid homeostasis through ER stress in 3D human brain organoids.
The Science of the total environment.
2022 Nov; 849(?):157815. doi:
10.1016/j.scitotenv.2022.157815. [PMID: 35931159] - Mina Sadat Izadi, Farzaneh Eskandari, Fatemeh Binayi, Mina Salimi, Fatemeh Sadat Rashidi, Mehdi Hedayati, Leila Dargahi, Hossein Ghanbarian, Homeira Zardooz. Oxidative and endoplasmic reticulum stress develop adverse metabolic effects due to the high-fat high-fructose diet consumption from birth to young adulthood.
Life sciences.
2022 Nov; 309(?):120924. doi:
10.1016/j.lfs.2022.120924. [PMID: 36063978] - Jia-Huang Chen, Chia-Ter Chao, Jenq-Wen Huang, Kuan-Yu Hung, Shing-Hwa Liu, Der-Cherng Tarng, Chih-Kang Chiang. Early elimination of uremic toxin ameliorates AKI-to-CKD transition.
Clinical science (London, England : 1979).
2021 12; 135(23):2643-2658. doi:
10.1042/cs20210858. [PMID: 34796904] - Wenlai He, Dezhe Qin, Balun Li, Huimin Zhang, Xuedi Cheng, Jing Sun, Jinlian Hua, Sha Peng. Immortalized canine adipose-derived mesenchymal stem cells alleviate gentamicin-induced acute kidney injury by inhibiting endoplasmic reticulum stress in mice and dogs.
Research in veterinary science.
2021 May; 136(?):39-50. doi:
10.1016/j.rvsc.2021.02.001. [PMID: 33582313] - Jiayi Wang, Jiehan Zhang, Yan Ma, Yuxiao Zeng, Cheng Lu, Fenghua Yang, Nianxin Jiang, Xuan Zhang, Yuhua Wang, Yinghui Xu, Hanjing Hou, Shengyang Jiang, Shaowei Zhuang. WTAP promotes myocardial ischemia/reperfusion injury by increasing endoplasmic reticulum stress via regulating m6A modification of ATF4 mRNA.
Aging.
2021 03; 13(8):11135-11149. doi:
10.18632/aging.202770. [PMID: 33819187] - Amany Abdel-Ghaffar, Ghada G Elhossary, Atef M Mahmoud, Amany H M Elshazly, Olfat A Hassanin, Anisa Saleh, Sahar M Mansour, Fatma G Metwally, Laila K Hanafy, Sawsan H Karam, Neveen Darweesh, Ahmed Mostafa Ata. Effects of 4-phenylbutyric acid on the development of diabetic retinopathy in diabetic rats: regulation of endoplasmic reticulum stress-oxidative activation.
Archives of physiology and biochemistry.
2021 Mar; ?(?):1-11. doi:
10.1080/13813455.2021.1888302. [PMID: 33653182] - Fateme Binayi, Mehdi Moslemi, Fariba Khodagholi, Mehdi Hedayati, Homeira Zardooz. Long-term high-fat diet disrupts lipid metabolism and causes inflammation in adult male rats: possible intervention of endoplasmic reticulum stress.
Archives of physiology and biochemistry.
2020 Sep; ?(?):1-9. doi:
10.1080/13813455.2020.1808997. [PMID: 32907408] - Yongjie Xiong, Qirun Yin, Erhui Jin, Huatao Chen, Shaojun He. Selenium Attenuates Chronic Heat Stress-Induced Apoptosis via the Inhibition of Endoplasmic Reticulum Stress in Mouse Granulosa Cells.
Molecules (Basel, Switzerland).
2020 Jan; 25(3):. doi:
10.3390/molecules25030557. [PMID: 32012916] - Meng Yin, Zhong-Hua Li, Chen Wang, Ying Li, Hong Zhang, Hui-Bo Du, Zhen-Ao Zhao, Chun-Yu Niu, Zi-Gang Zhao. Stellate Ganglion Blockade repairs Intestinal Mucosal Barrier through suppression of Endoplasmic Reticulum Stress following Hemorrhagic Shock.
International journal of medical sciences.
2020; 17(14):2147-2154. doi:
10.7150/ijms.47662. [PMID: 32922175] - Yuxin Zhong, Baoqiang Wang, Shan Hu, Tingting Wang, Yumiao Zhang, Jinling Wang, Yuqing Liu, Hongxia Zhang. The role of endoplasmic reticulum stress in renal damage caused by acute mercury chloride poisoning.
The Journal of toxicological sciences.
2020; 45(9):589-598. doi:
10.2131/jts.45.589. [PMID: 32879258] - Chunxiao Yu, Fangjie Jiang, Meijie Zhang, Dandan Luo, Shanshan Shao, Jiajun Zhao, Ling Gao, Changting Zuo, Qingbo Guan. HC diet inhibited testosterone synthesis by activating endoplasmic reticulum stress in testicular Leydig cells.
Journal of cellular and molecular medicine.
2019 05; 23(5):3140-3150. doi:
10.1111/jcmm.14143. [PMID: 30884106] - Masayoshi Tochiya, Daisuke Hagiwara, Yoshinori Azuma, Takashi Miyata, Yoshiaki Morishita, Hidetaka Suga, Takeshi Onoue, Taku Tsunekawa, Hiroshi Takagi, Yoshihiro Ito, Shintaro Iwama, Motomitsu Goto, Ryoichi Banno, Hiroshi Arima. Chemical chaperone 4-phenylbutylate reduces mutant protein accumulation in the endoplasmic reticulum of arginine vasopressin neurons in a mouse model for familial neurohypophysial diabetes insipidus.
Neuroscience letters.
2018 08; 682(?):50-55. doi:
10.1016/j.neulet.2018.06.013. [PMID: 29886132] - Peili Zheng, Yu Lin, Feifei Wang, Renfei Luo, Tiezheng Zhang, Shan Hu, Pinning Feng, Xinling Liang, Chunling Li, Weidong Wang. 4-PBA improves lithium-induced nephrogenic diabetes insipidus by attenuating ER stress.
American journal of physiology. Renal physiology.
2016 10; 311(4):F763-F776. doi:
10.1152/ajprenal.00225.2016. [PMID: 27385737] - H Gao, X Y Zhang, L Y Yue, Z Y Liu, N N Jia, D X Chen, Z P Duan, F Ren. [Role of endoplasmic reticulum stress-mediated glycogen synthase kinase 3β activity in pathogenesis of acute liver failure in mice].
Zhonghua yi xue za zhi.
2016 Sep; 96(34):2734-2738. doi:
10.3760/cma.j.issn.0376-2491.2016.34.010. [PMID: 27667108] - Yu-Feng Song, Chao Huang, Xi Shi, Ya-Xiong Pan, Xu Liu, Zhi Luo. Endoplasmic reticulum stress and dysregulation of calcium homeostasis mediate Cu-induced alteration in hepatic lipid metabolism of javelin goby Synechogobius hasta.
Aquatic toxicology (Amsterdam, Netherlands).
2016 Jun; 175(?):20-9. doi:
10.1016/j.aquatox.2016.03.003. [PMID: 26991751] - A Mohammadi, A Gholamhoseyniannajar, M M Yaghoobi, Y Jahani, Z Vahabzadeh. Expression levels of heat shock protein 60 and glucose-regulated protein 78 in response to trimethylamine-N-oxide treatment in murine macrophage J774A.1 cell line.
Cellular and molecular biology (Noisy-le-Grand, France).
2015 Sep; 61(4):94-100. doi:
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Journal of immunology research.
2015; 2015(?):428508. doi:
10.1155/2015/428508. [PMID: 25977931] - Meng-Han Lin, Jui-Hung Yen, Ching-Yi Weng, Lisu Wang, Choi-Lan Ha, Ming-Jiuan Wu. Lipid peroxidation end product 4-hydroxy-trans-2-nonenal triggers unfolded protein response and heme oxygenase-1 expression in PC12 cells: Roles of ROS and MAPK pathways.
Toxicology.
2014 Jan; 315(?):24-37. doi:
10.1016/j.tox.2013.11.007. [PMID: 24291486] - D Fu, M Wu, J Zhang, M Du, S Yang, S M Hammad, K Wilson, J Chen, T J Lyons. Mechanisms of modified LDL-induced pericyte loss and retinal injury in diabetic retinopathy.
Diabetologia.
2012 Nov; 55(11):3128-40. doi:
10.1007/s00125-012-2692-0. [PMID: 22935961] - Shaohua Zhu, Yan Wang, Jing Jin, Cuiwen Guan, Mei Li, Chen Xi, Zizhang Ouyang, Meiwan Chen, Yuwen Qiu, Min Huang, Zhiying Huang. Endoplasmic reticulum stress mediates aristolochic acid I-induced apoptosis in human renal proximal tubular epithelial cells.
Toxicology in vitro : an international journal published in association with BIBRA.
2012 Aug; 26(5):663-71. doi:
10.1016/j.tiv.2012.03.005. [PMID: 22445861] - Masahiko Ohta, Hiroyuki Kawano, Tatsuto Notsu, Hiroyasu Naba, Kazunori Imada. Eicosapentaenoic acid attenuates statin-induced ER stress and toxicity in myoblast.
Biochemical and biophysical research communications.
2012 Jul; 424(2):301-7. doi:
10.1016/j.bbrc.2012.06.111. [PMID: 22749998] - Jennifer Rieusset, Marie-Agnès Chauvin, Annie Durand, Amélie Bravard, Fabienne Laugerette, Marie-Caroline Michalski, Hubert Vidal. Reduction of endoplasmic reticulum stress using chemical chaperones or Grp78 overexpression does not protect muscle cells from palmitate-induced insulin resistance.
Biochemical and biophysical research communications.
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