Tocotrienol (BioDeep_00001871504)
代谢物信息卡片
Tocotrienol
化学式: C26H38O2 (382.28716479999997)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC(=CCCC(=CCCC(=CCCC1(CCC2=C(O1)C=CC(=C2)O)C)C)C)C
InChI: InChI=1S/C26H38O2/c1-20(2)9-6-10-21(3)11-7-12-22(4)13-8-17-26(5)18-16-23-19-24(27)14-15-25(23)28-26/h9,11,13-15,19,27H,6-8,10,12,16-18H2,1-5H3/b21-11+,22-13+
描述信息
D020011 - Protective Agents > D000975 - Antioxidants > D024508 - Tocotrienols
D018977 - Micronutrients > D014815 - Vitamins
同义名列表
1 个代谢物同义名
数据库引用编号
7 个数据库交叉引用编号
- ChEBI: CHEBI:197268
- PubChem: 9929901
- DrugBank: DB12647
- ChEMBL: CHEMBL120643
- MeSH: Tocotrienols
- CAS: 97530-73-9
- CAS: 6829-55-6
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
4 个相关的物种来源信息
- 477925 Iryanthera lancifolia: 10.1016/S0031-9422(97)01092-3
- 193516 Hippophae rhamnoides: 10.1016/J.PHYMED.2007.03.018
- 477925 Iryanthera lancifolia: 10.1016/S0031-9422(97)01092-3
- 193516 Hippophae rhamnoides: 10.1016/J.PHYMED.2007.03.018
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Hao Tian, Yi-Fang Li, Gen-Long Jiao, Wan-Yang Sun, Rong-Rong He. Unveiling the antioxidant superiority of α-tocopherol: Implications for vitamin E nomenclature and classification.
Free radical biology & medicine.
2024 Apr; 216(?):46-49. doi:
10.1016/j.freeradbiomed.2024.03.003. [PMID: 38458392] - Naicheng Liu, Peng Zhang, Mingyang Xue, Mengwei Zhang, Zhenyu Huang, Chen Xu, Yan Meng, Yuding Fan, Wei Liu, Feixiang Zhang, Peng Chen, Yong Zhou. Hypolipidemic Effect of Rice Bran Oil Extract Tocotrienol in High-Fat Diet-Induced Hyperlipidemia Zebrafish (Danio Rerio) Induced by High-Fat Diet.
International journal of molecular sciences.
2024 Mar; 25(5):. doi:
10.3390/ijms25052954. [PMID: 38474201] - Zhanghui Zeng, Wenqian Zhang, Yaqi Shi, Haonan Wei, Chun Zhou, Xiaoping Huang, Zhehao Chen, Taihe Xiang, Lilin Wang, Ning Han, Hongwu Bian. Coordinated Transcriptome and Metabolome Analyses of a Barley hvhggt Mutant Reveal a Critical Role of Tocotrienols in Endosperm Starch Accumulation.
Journal of agricultural and food chemistry.
2024 Jan; 72(2):1146-1161. doi:
10.1021/acs.jafc.3c06301. [PMID: 38181192] - Serafino Suriano, Pasquale Codianni, Anna Iannucci. Carotenoids and tocols comparison in different Subspecies of Triticum turgidum and aestivum.
Food research international (Ottawa, Ont.).
2023 Dec; 174(Pt 1):113620. doi:
10.1016/j.foodres.2023.113620. [PMID: 37986473] - Marian Czauderna, Wiktoria Wojtak, Małgorzata Białek, Agnieszka Białek. Optimization of high-efficient pre-column sample treatments and C18-UFLC method for selective quantification of selected chemical forms of tocopherol and tocotrienol in diverse foods.
Food chemistry.
2023 Nov; 437(Pt 2):137909. doi:
10.1016/j.foodchem.2023.137909. [PMID: 37939419] - Ju-Yen Fu, Puvaneswari Meganathan, Nisanthei Gunasegaran, Doryn Meam Yee Tan. Effect of nano-delivery systems on the bioavailability and tissue biodistribution of vitamin E tocotrienols.
Food research international (Ottawa, Ont.).
2023 Sep; 171(?):113048. doi:
10.1016/j.foodres.2023.113048. [PMID: 37330852] - Anji Reddy Konda, Malleswari Gelli, Connor Pedersen, Rebecca E Cahoon, Chunyu Zhang, Toshihiro Obata, Edgar B Cahoon. Vitamin E biofortification: Maximizing oilseed tocotrienol and total vitamin E tocochromanol production by use of metabolic bypass combinations.
Metabolic engineering.
2023 Jul; ?(?):. doi:
10.1016/j.ymben.2023.06.011. [PMID: 37429412] - Helison de Oliveira Carvalho, Ana Laura Ribeiro Sauma, Aline Lopes do Nascimento, Abrahão Victor Tavares de Lima Teixeira, Danna Emanuelle Santos Gonçalves, Lauana Gomes, Gabriel da Costa Furtado, Heitor Ribeiro da Silva, Gisele Custódio de Souza, Arlindo César Matias Pereira, José Carlos Tavares Carvalho. Intramuscular compatibility of an injectable anti-inflammatory nanodispersion from a standardized Bixa orellana oil (Chronic®): a toxicological study in Wistar rats.
Inflammopharmacology.
2023 Feb; ?(?):. doi:
10.1007/s10787-023-01162-8. [PMID: 36853419] - Kok-Yong Chin, Sophia Ogechi Ekeuku, Deborah Chia Hsin Chew, Anne Trias. Tocotrienol in the Management of Nonalcoholic Fatty Liver Disease: A Systematic Review.
Nutrients.
2023 Feb; 15(4):. doi:
10.3390/nu15040834. [PMID: 36839192] - Aleksander Siger, Paweł Górnaś. Free tocopherols and tocotrienols in 82 plant species' oil: Chemotaxonomic relation as demonstrated by PCA and HCA.
Food research international (Ottawa, Ont.).
2023 02; 164(?):112386. doi:
10.1016/j.foodres.2022.112386. [PMID: 36737971] - Salisa Chumsantea, Apiwat Jiruttisakul, Akkaradech Nakornsadet, Piraporn Sombutsuwan, Kornkanok Aryusuk. Simultaneous Determination of Vitamin E and γ-Oryzanol in Rice Bran Oil via HPSEC-PDA without Sample Pretreatment.
Journal of oleo science.
2023; 72(7):655-665. doi:
10.5650/jos.ess22257. [PMID: 37380482] - Paweł Górnaś, Georgijs Baškirovs, Aleksander Siger. Free and Esterified Tocopherols, Tocotrienols and Other Extractable and Non-Extractable Tocochromanol-Related Molecules: Compendium of Knowledge, Future Perspectives and Recommendations for Chromatographic Techniques, Tools, and Approaches Used for Tocochromanol Determination.
Molecules (Basel, Switzerland).
2022 Oct; 27(19):. doi:
10.3390/molecules27196560. [PMID: 36235100] - Federica Pasini, Ana Maria Gómez-Caravaca, Thierry Blasco, Jelena Cvejić, Maria Fiorenza Caboni, Vito Verardo. Assessment of Lipid Quality in Commercial Omega-3 Supplements Sold in the French Market.
Biomolecules.
2022 Sep; 12(10):. doi:
10.3390/biom12101361. [PMID: 36291569] - Sophia Ogechi Ekeuku, Elvy Suhana Mohd Ramli, Norfarahin Abdullah Sani, Norzana Abd Ghafar, Ima Nirwana Soelaiman, Kok-Yong Chin. Tocotrienol as a Protecting Agent against Glucocorticoid-Induced Osteoporosis: A Mini Review of Potential Mechanisms.
Molecules (Basel, Switzerland).
2022 Sep; 27(18):. doi:
10.3390/molecules27185862. [PMID: 36144598] - Muhammad Zulfiqah Sadikan, Nurul Alimah Abdul Nasir, Igor Iezhitsa, Renu Agarwal. Antioxidant and anti-apoptotic effects of tocotrienol-rich fraction against streptozotocin-induced diabetic retinopathy in rats.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
2022 Sep; 153(?):113533. doi:
10.1016/j.biopha.2022.113533. [PMID: 36076612] - Zhongnan Wu, Xiaoyong Dai, Wenzhi Wang, Xianfang Zhang, Jiawei Chen, Jing Liu, Laiqiang Huang, Yaolan Li, Shuixing Zhang, Guocai Wang, Yubo Zhang. Polyprenylated Benzophenones and Tocotrienol Derivatives from the Edible Fruits of Garcinia oblongifolia Champ. ex Benth. and Their Cytotoxicity Activity.
Journal of agricultural and food chemistry.
2022 Aug; 70(34):10506-10520. doi:
10.1021/acs.jafc.2c04216. [PMID: 35997267] - Jean-Marie Savignac, Vessela Atanasova, Sylvain Chéreau, Véronique Ortéga, Florence Richard-Forget. Role of Tocochromanols in Tolerance of Cereals to Biotic Stresses: Specific Focus on Pathogenic and Toxigenic Fungal Species.
International journal of molecular sciences.
2022 Aug; 23(16):. doi:
10.3390/ijms23169303. [PMID: 36012567] - Daisuke Watase, Shuichi Setoguchi, Nami Nagata-Akaho, Shotaro Goto, Hirofumi Yamakawa, Ayano Yamada, Mitsuhisa Koga, Yoshiharu Karube, Kazuhisa Matsunaga, Jiro Takata. Cationic N,N-Dimethylglycine Ester Prodrug of 2R-α-Tocotrienol Promotes Intestinal Absorption via Efficient Self-Micellization with Intrinsic Bile Acid Anion.
Molecules (Basel, Switzerland).
2022 Apr; 27(9):. doi:
10.3390/molecules27092727. [PMID: 35566078] - Yugo Kato, Yoshinori Aoki, Chikako Kiyose, Koji Fukui. Tocotrienols Attenuate White Adipose Tissue Accumulation and Improve Serum Cholesterol Concentration in High-Fat Diet-Treated Mice.
Molecules (Basel, Switzerland).
2022 Mar; 27(7):. doi:
10.3390/molecules27072188. [PMID: 35408585] - Aneta Wojdyło, Igor Piotr Turkiewicz, Karolina Tkacz, Francisca Hernandez. Fruit tree leaves as valuable new source of tocopherol and tocotrienol compounds.
Journal of the science of food and agriculture.
2022 Mar; 102(4):1466-1474. doi:
10.1002/jsfa.11481. [PMID: 34398983] - Yifei Lu, Yihan Zhang, Zhenyu Pan, Chao Yang, Lin Chen, Yuanyuan Wang, Dengfeng Xu, Hui Xia, Shaokang Wang, Shiqing Chen, Yoong Jun Hao, Guiju Sun. Potential "Therapeutic" Effects of Tocotrienol-Rich Fraction (TRF) and Carotene "Against" Bleomycin-Induced Pulmonary Fibrosis in Rats via TGF-β/Smad, PI3K/Akt/mTOR and NF-κB Signaling Pathways.
Nutrients.
2022 Mar; 14(5):. doi:
10.3390/nu14051094. [PMID: 35268069] - Farah Zaaboul, YuanFa Liu. Vitamin E in foodstuff: Nutritional, analytical, and food technology aspects.
Comprehensive reviews in food science and food safety.
2022 03; 21(2):964-998. doi:
10.1111/1541-4337.12924. [PMID: 35181987] - H Jervoise N Andreyev, Jennifer Matthews, Carolyn Adams, Lone Gothard, Claire Lucy, Holly Tovey, Sue Boyle, Selvakumar Anbalagan, Annette Musallam, John Yarnold, David Abraham, Judith Bliss, Bahja Ahmed Abdi, Alexandra Taylor, Martin Hauer-Jensen. Randomised single centre double-blind placebo controlled phase II trial of Tocovid SupraBio in combination with pentoxifylline in patients suffering long-term gastrointestinal adverse effects of radiotherapy for pelvic cancer: The PPALM study.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.
2022 03; 168(?):130-137. doi:
10.1016/j.radonc.2022.01.024. [PMID: 35093409] - Mateus Alves Batista, Abrahão Victor Tavares de Lima Teixeira Dos Santos, Aline Lopes do Nascimento, Luiz Fernando Moreira, Indira Ramos Senna Souza, Heitor Ribeiro da Silva, Arlindo César Matias Pereira, Lorane Izabel da Silva Hage-Melim, José Carlos Tavares Carvalho. Potential of the Compounds from Bixa orellana Purified Annatto Oil and Its Granules (Chronic®) against Dyslipidemia and Inflammatory Diseases: In Silico Studies with Geranylgeraniol and Tocotrienols.
Molecules (Basel, Switzerland).
2022 Feb; 27(5):. doi:
10.3390/molecules27051584. [PMID: 35268686] - Kasthuri Bai Magalingam, Sushela Devi Somanath, Shadab Md, Nagaraja Haleagrahara, Ju-Yen Fu, Kanga Rani Selvaduray, Ammu Kutty Radhakrishnan. Tocotrienols protect differentiated SH-SY5Y human neuroblastoma cells against 6-hydroxydopamine-induced cytotoxicity by ameliorating dopamine biosynthesis and dopamine receptor D2 gene expression.
Nutrition research (New York, N.Y.).
2022 02; 98(?):27-40. doi:
10.1016/j.nutres.2021.09.003. [PMID: 35065349] - Qing Jiang. Metabolism of natural forms of vitamin E and biological actions of vitamin E metabolites.
Free radical biology & medicine.
2022 02; 179(?):375-387. doi:
10.1016/j.freeradbiomed.2021.11.012. [PMID: 34785321] - Karolina Tkacz, Ángel Gil-Izquierdo, Sonia Medina, Igor Piotr Turkiewicz, Raúl Domínguez-Perles, Paulina Nowicka, Aneta Wojdyło. Phytoprostanes, phytofurans, tocopherols, tocotrienols, carotenoids and free amino acids and biological potential of sea buckthorn juices.
Journal of the science of food and agriculture.
2022 Jan; 102(1):185-197. doi:
10.1002/jsfa.11345. [PMID: 34061348] - Anna Markowska, Michał Antoszczak, Janina Markowska, Adam Huczyński. Role of Vitamin E in Selected Malignant Neoplasms in Women.
Nutrition and cancer.
2022; 74(4):1163-1170. doi:
10.1080/01635581.2021.1952626. [PMID: 34278890] - Chee Chin Chu, Zafarizal Aldrin Bin Azizul Hasan, Chin Ping Tan, Kar Lin Nyam. In Vitro Antiaging Evaluation of Sunscreen Formulated from Nanostructured Lipid Carrier and Tocotrienol-Rich Fraction.
Journal of pharmaceutical sciences.
2021 12; 110(12):3929-3936. doi:
10.1016/j.xphs.2021.08.020. [PMID: 34425132] - Phui Yee Tan, Tai Boon Tan, Hon Weng Chang, William W Mwangi, Beng Ti Tey, Eng Seng Chan, Oi Ming Lai, Yuanfa Liu, Yong Wang, Chin Ping Tan. Pickering emulsion-templated ionotropic gelation of tocotrienol microcapsules: effects of alginate and chitosan concentrations and gelation process parameters.
Journal of the science of food and agriculture.
2021 Nov; 101(14):5963-5971. doi:
10.1002/jsfa.11249. [PMID: 33840091] - Mototada Shichiri, Noriko Ishida, Yoshinori Aoki, Taisuke Koike, Yoshihisa Hagihara. Stress-activated leukocyte 12/15-lipoxygenase metabolite enhances struggle behaviour and tocotrienols relieve stress-induced behaviour alteration.
Free radical biology & medicine.
2021 11; 175(?):171-183. doi:
10.1016/j.freeradbiomed.2021.08.236. [PMID: 34474105] - Danial Efendy Goon, Sharaniza Ab-Rahim, Amir Hakimi Mohd Sakri, Musalmah Mazlan, Jen Kit Tan, Mardiana Abdul Aziz, Norizal Mohd Noor, Effendi Ibrahim, Siti Hamimah Sheikh Abdul Kadir. Untargeted serum metabolites profiling in high-fat diet mice supplemented with enhanced palm tocotrienol-rich fraction using UHPLC-MS.
Scientific reports.
2021 10; 11(1):21001. doi:
10.1038/s41598-021-00454-9. [PMID: 34697380] - Pei Fen Chuar, Yeek Tat Ng, Sonia Chew Wen Phang, Yan Yi Koay, J-Ian Ho, Loon Shin Ho, Nevein Philip Botross Henien, Badariah Ahmad, Khalid Abdul Kadir. Tocotrienol-Rich Vitamin E (Tocovid) Improved Nerve Conduction Velocity in Type 2 Diabetes Mellitus Patients in a Phase II Double-Blind, Randomized Controlled Clinical Trial.
Nutrients.
2021 Oct; 13(11):. doi:
10.3390/nu13113770. [PMID: 34836025] - Tapan Behl, Sachin Kumar, Aayush Sehgal, Sukhbir Singh, Shilpa Kumari, Mihaela Cristina Brisc, Mihai Alexandru Munteanu, Ciprian Brisc, Camelia Liana Buhas, Claudia Judea-Pusta, Camelia Liana Buhas, Claudia Judea-Pusta, Delia Carmen Nistor-Cseppento, Simona Bungau. Rice bran, an off-shoot to newer therapeutics in neurological disorders.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
2021 Aug; 140(?):111796. doi:
10.1016/j.biopha.2021.111796. [PMID: 34098194] - Kacper Szewczyk, Aleksandra Chojnacka, Magdalena Górnicka. Tocopherols and Tocotrienols-Bioactive Dietary Compounds; What Is Certain, What Is Doubt?.
International journal of molecular sciences.
2021 Jun; 22(12):. doi:
10.3390/ijms22126222. [PMID: 34207571] - Aleksander Siger, Wojciech Antkowiak, Krzysztof Dwiecki, Ewa Rokosik, Magdalena Rudzińska. Nutlets of Tilia cordata Mill. and Tilia platyphyllos Scop. - Source of bioactive compounds.
Food chemistry.
2021 Jun; 346(?):128888. doi:
10.1016/j.foodchem.2020.128888. [PMID: 33385911] - Shanmukh S Salimath, Trevor B Romsdahl, Anji Reddy Konda, Wei Zhang, Edgar B Cahoon, Michael K Dowd, Thomas C Wedegaertner, Kater D Hake, Kent D Chapman. Production of tocotrienols in seeds of cotton (Gossypium hirsutum L.) enhances oxidative stability and offers nutraceutical potential.
Plant biotechnology journal.
2021 06; 19(6):1268-1282. doi:
10.1111/pbi.13557. [PMID: 33492748] - Nur-Vaizura Mohamad, Soelaiman Ima-Nirwana, Kok-Yong Chin. Therapeutic potential of annatto tocotrienol with self-emulsifying drug delivery system in a rat model of postmenopausal bone loss.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
2021 May; 137(?):111368. doi:
10.1016/j.biopha.2021.111368. [PMID: 33582449] - Chwan-Li Shen, Sivapriya Ramamoorthy, Gurvinder Kaur, Jannette M Dufour, Rui Wang, Huanbiao Mo, Bruce A Watkins. Dietary Annatto-Extracted Tocotrienol Reduces Inflammation and Oxidative Stress, and Improves Macronutrient Metabolism in Obese Mice: A Metabolic Profiling Study.
Nutrients.
2021 Apr; 13(4):. doi:
10.3390/nu13041267. [PMID: 33924335] - Valentina Cossiga, Vincenzo Lembo, Cecilia Nigro, Paola Mirra, Claudia Miele, Valeria D'Argenio, Alessia Leone, Giovanna Mazzone, Iolanda Veneruso, Maria Guido, Francesco Beguinot, Nicola Caporaso, Filomena Morisco. The Combination of Berberine, Tocotrienols and Coffee Extracts Improves Metabolic Profile and Liver Steatosis by the Modulation of Gut Microbiota and Hepatic miR-122 and miR-34a Expression in Mice.
Nutrients.
2021 Apr; 13(4):. doi:
10.3390/nu13041281. [PMID: 33924725] - Uyen Nguyen Huynh Phuong, Thao Pham Thi Phuong, Kiyoshi Imamura, Yoshiaki Kitaya, Jun Hidema, Masakazu Furuta, Maeda Yasuaki. The characterization of tocols in different plants parts of six Japanese rice cultivars relating to their UVB-sensitivity.
Plant physiology and biochemistry : PPB.
2021 Apr; 161(?):48-53. doi:
10.1016/j.plaphy.2021.01.045. [PMID: 33578284] - Yan Yi Koay, Gerald Chen Jie Tan, Sonia Chew Wen Phang, J-Ian Ho, Pei Fen Chuar, Loon Shin Ho, Badariah Ahmad, Khalid Abdul Kadir. A Phase IIb Randomized Controlled Trial Investigating the Effects of Tocotrienol-Rich Vitamin E on Diabetic Kidney Disease.
Nutrients.
2021 Jan; 13(1):. doi:
10.3390/nu13010258. [PMID: 33477404] - Nur-Vaizura Mohamad, Soelaiman Ima-Nirwana, Kok-Yong Chin. Self-emulsified annatto tocotrienol improves bone histomorphometric parameters in a rat model of oestrogen deficiency through suppression of skeletal sclerostin level and RANKL/OPG ratio.
International journal of medical sciences.
2021; 18(16):3665-3673. doi:
10.7150/ijms.64045. [PMID: 34790038] - Fumiaki Beppu, Aimi Sakuma, Satoshi Kasatani, Yoshinori Aoki, Naohiro Gotoh. Application of Partial Hydrogenation for the Generation of Minor Tocochromanol Homologs and Functional Evaluation of Hydrogenated Tocotrienol-rich Vitamin E Oil in Diabetic Obese Mice.
Journal of oleo science.
2021; 70(1):103-112. doi:
10.5650/jos.ess20233. [PMID: 33431764] - Moamen M Elmassry, Eunhee Chung, Jay J Cao, Abdul N Hamood, Chwan-Li Shen. Osteoprotective effect of green tea polyphenols and annatto-extracted tocotrienol in obese mice is associated with enhanced microbiome vitamin K2 biosynthetic pathways.
The Journal of nutritional biochemistry.
2020 12; 86(?):108492. doi:
10.1016/j.jnutbio.2020.108492. [PMID: 32920088] - Yunqi Wen, Lili Xu, Changhu Xue, Xiaoming Jiang, Zihao Wei. Assessing the Impact of Oil Types and Grades on Tocopherol and Tocotrienol Contents in Vegetable Oils with Chemometric Methods.
Molecules (Basel, Switzerland).
2020 Nov; 25(21):. doi:
10.3390/molecules25215076. [PMID: 33139648] - Bin Shen, Pingping Zhou, Xue Jiao, Zhen Yao, Lidan Ye, Hongwei Yu. Fermentative production of Vitamin E tocotrienols in Saccharomyces cerevisiae under cold-shock-triggered temperature control.
Nature communications.
2020 10; 11(1):5155. doi:
10.1038/s41467-020-18958-9. [PMID: 33056995] - Zhanghui Zeng, Ning Han, Cuicui Liu, B Buerte, Chenlu Zhou, Jianshu Chen, Mengyao Wang, Yuhong Zhang, Yawei Tang, Muyuan Zhu, Junhui Wang, Yinong Yang, Hongwu Bian. Functional dissection of HGGT and HPT in barley vitamin E biosynthesis via CRISPR/Cas9-enabled genome editing.
Annals of botany.
2020 10; 126(5):929-942. doi:
10.1093/aob/mcaa115. [PMID: 32575125] - Andrea Casadesús, Alba Arabia, Ricard Pujolriu, Sergi Munné-Bosch. Differential accumulation of tocochromanols in photosynthetic and non-photosynthetic tissues of strawberry plants subjected to reiterated water deficit.
Plant physiology and biochemistry : PPB.
2020 Oct; 155(?):868-876. doi:
10.1016/j.plaphy.2020.06.038. [PMID: 32896766] - Pardis Irandoost, Naimeh Mesri Alamdari, Atoosa Saidpour, Farzad Shidfar, Farnaz Farsi, Mohammad Asghari Jafarabadi, Mohammad Reza Alivand, Mohammadreza Vafa. The effect of royal jelly and tocotrienol-rich fraction along with calorie restriction on hypothalamic endoplasmic reticulum stress and adipose tissue inflammation in diet-induced obese rats.
BMC research notes.
2020 Aug; 13(1):409. doi:
10.1186/s13104-020-05258-0. [PMID: 32867829] - Shuping Zuo, Guiping Wang, QuanLe Han, Hongling Xiao, Heitor O Santos, David Avelar Rodriguez, Vahid Khani, Jianlei Tang. The effects of tocotrienol supplementation on lipid profile: A meta-analysis of randomized controlled trials.
Complementary therapies in medicine.
2020 Aug; 52(?):102450. doi:
10.1016/j.ctim.2020.102450. [PMID: 32951713] - Yeek Tat Ng, Sonia Chew Wen Phang, Gerald Chen Jie Tan, En Yng Ng, Nevein Philip Botross Henien, Uma Devi M Palanisamy, Badariah Ahmad, Khalid Abdul Kadir. The Effects of Tocotrienol-Rich Vitamin E (Tocovid) on Diabetic Neuropathy: A Phase II Randomized Controlled Trial.
Nutrients.
2020 May; 12(5):. doi:
10.3390/nu12051522. [PMID: 32456230] - Weijian Shen, Hong Wang, Huiyuan Lu, Keyao Yu, Guoshen Hu, Xueyuan Wei, Bin Wu. [Determination of eight vitamin E in vegetable oils by gas chromatography-mass spectrometry and its application on authentication of sesame oil].
Se pu = Chinese journal of chromatography.
2020 May; 38(5):595-599. doi:
10.3724/sp.j.1123.2019.09011. [PMID: 34213245] - Eunhee Chung, Moamen M Elmassry, Pratibha Kottapalli, Kameswara Rao Kottapalli, Gurvinder Kaur, Jannette M Dufour, Kandis Wright, Latha Ramalingam, Naima Moustaid-Moussa, Rui Wang, Abdul N Hamood, Chwan-Li Shen. Metabolic benefits of annatto-extracted tocotrienol on glucose homeostasis, inflammation, and gut microbiome.
Nutrition research (New York, N.Y.).
2020 05; 77(?):97-107. doi:
10.1016/j.nutres.2020.04.001. [PMID: 32438021] - Aleksandra Szulczewska-Remi, Małgorzata Nogala-Kalucka. Studies on the growth inhibiting and non-cytotoxic effects of tocotrienols on selected cancer cell lines.
Acta scientiarum polonorum. Technologia alimentaria.
2020 Apr; 19(2):139-147. doi:
10.17306/j.afs.0787. [PMID: 32600010] - Watchara Sangsopha, Florian T Schevenels, Ratsami Lekphrom, Somdej Kanokmedhakul. A new tocotrienol from the roots and branches of Allophylus cobbe (L.) Raeusch (Sapindaceae).
Natural product research.
2020 Apr; 34(7):988-994. doi:
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BMJ open.
2020 03; 10(3):e034338. doi:
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Bioscience, biotechnology, and biochemistry.
2020 Mar; 84(3):526-535. doi:
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Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
2020 Feb; 136(?):111036. doi:
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The Journal of nutrition.
2020 02; 150(2):222-230. doi:
10.1093/jn/nxz217. [PMID: 31495894] - Lulu Farhana, Sarah Sarkar, Pratima Nangia-Makker, Yingjie Yu, Pramod Khosla, Edi Levi, Asfar Azmi, Adhip P N Majumdar. Natural agents inhibit colon cancer cell proliferation and alter microbial diversity in mice.
PloS one.
2020; 15(3):e0229823. doi:
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Drug design, development and therapy.
2020; 14(?):969-976. doi:
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Nutrition and cancer.
2020; 72(4):653-661. doi:
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Natural product research.
2020 Jan; 34(2):296-299. doi:
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PloS one.
2020; 15(11):e0241112. doi:
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Journal of integrative medicine.
2020 Jan; 18(1):68-79. doi:
10.1016/j.joim.2019.11.005. [PMID: 31812339] - Zaida Zainal, Afiqah Abdul Rahim, Ammu Kutty Radhakrishnan, Sui Kiat Chang, Huzwah Khaza'ai. Investigation of the curative effects of palm vitamin E tocotrienols on autoimmune arthritis disease in vivo.
Scientific reports.
2019 11; 9(1):16793. doi:
10.1038/s41598-019-53424-7. [PMID: 31727971] - Paula Muñoz, Sergi Munné-Bosch. Vitamin E in Plants: Biosynthesis, Transport, and Function.
Trends in plant science.
2019 11; 24(11):1040-1051. doi:
10.1016/j.tplants.2019.08.006. [PMID: 31606282] - Agnieszka Trela, Renata Szymańska. Less widespread plant oils as a good source of vitamin E.
Food chemistry.
2019 Oct; 296(?):160-166. doi:
10.1016/j.foodchem.2019.05.185. [PMID: 31202300] - Angelo Di Vincenzo, Claudio Tana, Hamza El Hadi, Claudio Pagano, Roberto Vettor, Marco Rossato. Antioxidant, Anti-Inflammatory, and Metabolic Properties of Tocopherols and Tocotrienols: Clinical Implications for Vitamin E Supplementation in Diabetic Kidney Disease.
International journal of molecular sciences.
2019 Oct; 20(20):. doi:
10.3390/ijms20205101. [PMID: 31618817] - Sok Kuan Wong, Kok-Yong Chin, Soelaiman Ima-Nirwana. The Effects of Tocotrienol on Bone Peptides in a Rat Model of Osteoporosis Induced by Metabolic Syndrome: The Possible Communication between Bone Cells.
International journal of environmental research and public health.
2019 09; 16(18):. doi:
10.3390/ijerph16183313. [PMID: 31505801] - Kok-Yong Chin, Sok Kuan Wong, Fadhlullah Zuhair Japar Sidik, Juliana Abdul Hamid, Nurul Hafizah Abas, Elvy Suhana Mohd Ramli, Sabarul Afian Mokhtar, Sakthiswary Rajalingham, Soelaiman Ima Nirwana. The Effects of Annatto Tocotrienol Supplementation on Cartilage and Subchondral Bone in an Animal Model of Osteoarthritis Induced by Monosodium Iodoacetate.
International journal of environmental research and public health.
2019 08; 16(16):. doi:
10.3390/ijerph16162897. [PMID: 31412648] - Zhen-Shan Zhang, Li-Xia Zhang, Qing-Fang Xie, Li-Ming Che. Effect of Accelerated Storage on Fatty Acids, Thermal Properties and Bioactive Compounds of Kenaf Seed Oil.
Journal of food science.
2019 Aug; 84(8):2121-2127. doi:
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Fitoterapia.
2019 Jul; 136(?):104175. doi:
10.1016/j.fitote.2019.104175. [PMID: 31095982] - Linwu Ran, Anna B Liu, Mao-Jung Lee, Ping Xie, Yong Lin, Chung S Yang. Effects of antibiotics on degradation and bioavailability of different vitamin E forms in mice.
BioFactors (Oxford, England).
2019 May; 45(3):450-462. doi:
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The Journal of nutritional biochemistry.
2019 05; 67(?):36-43. doi:
10.1016/j.jnutbio.2019.01.021. [PMID: 30852322] - Koji Fukui, Masashi Shirai, Takeyuki Ninuma, Yugo Kato. Anti-Obesity Effects of Tocotrienols and Bran in High-Fat Diet-Treated Mice.
Nutrients.
2019 Apr; 11(4):. doi:
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International journal of molecular sciences.
2019 Apr; 20(7):. doi:
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Journal of the science of food and agriculture.
2019 Mar; 99(5):2078-2087. doi:
10.1002/jsfa.9400. [PMID: 30298520] - Kok-Lun Pang, Kok-Yong Chin. The Role of Tocotrienol in Protecting Against Metabolic Diseases.
Molecules (Basel, Switzerland).
2019 Mar; 24(5):. doi:
10.3390/molecules24050923. [PMID: 30845769] - Chengxin Wang, Zhenhua Duan, Liuping Fan, Jinwei Li. Supercritical CO₂ Fluid Extraction of Elaeagnus mollis Diels Seed Oil and Its Antioxidant Ability.
Molecules (Basel, Switzerland).
2019 Mar; 24(5):. doi:
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Plant foods for human nutrition (Dordrecht, Netherlands).
2019 Mar; 74(1):91-98. doi:
10.1007/s11130-018-0706-x. [PMID: 30552561] - Matheus Baseggio, Matthew Murray, Maria Magallanes-Lundback, Nicholas Kaczmar, James Chamness, Edward S Buckler, Margaret E Smith, Dean DellaPenna, William F Tracy, Michael A Gore. Genome-Wide Association and Genomic Prediction Models of Tocochromanols in Fresh Sweet Corn Kernels.
The plant genome.
2019 03; 12(1):. doi:
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Journal of oleo science.
2019 Jan; 68(1):21-31. doi:
10.5650/jos.ess18179. [PMID: 30542012] - Junmin Ji, Zhengfa Ge, Yeshen Feng, Xuede Wang. Lipid Characterization of Chinese Wild Hazelnuts (Corylus mandshurica Maxim.).
Journal of oleo science.
2019 Jan; 68(1):13-20. doi:
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Journal of nutritional science and vitaminology.
2019; 65(4):318-327. doi:
10.3177/jnsv.65.318. [PMID: 31474681] - Annette Abraham, Ajoe John Kattoor, Tom Saldeen, Jawahar L Mehta. Vitamin E and its anticancer effects.
Critical reviews in food science and nutrition.
2019; 59(17):2831-2838. doi:
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Biological & pharmaceutical bulletin.
2019; 42(6):1034-1037. doi:
10.1248/bpb.b18-00924. [PMID: 31155579] - Laura Siles, Leonor Alegre, Ariadna González-Solís, Edgar B Cahoon, Sergi Munné-Bosch. Transcriptional Regulation of Vitamin E Biosynthesis during Germination of Dwarf Fan Palm Seeds.
Plant & cell physiology.
2018 Dec; 59(12):2490-2501. doi:
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Bone.
2018 11; 116(?):8-21. doi:
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Journal of food science.
2018 Oct; 83(10):2439-2447. doi:
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Redox biology.
2018 10; 19(?):28-36. doi:
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Biochimie.
2018 Oct; 153(?):181-202. doi:
10.1016/j.biochi.2018.07.009. [PMID: 30031877] - Suzanne May Quinn Tan, Yilynn Chiew, Badariah Ahmad, Khalid Abdul Kadir. Tocotrienol-Rich Vitamin E from Palm Oil (Tocovid) and Its Effects in Diabetes and Diabetic Nephropathy: A Pilot Phase II Clinical Trial.
Nutrients.
2018 Sep; 10(9):. doi:
10.3390/nu10091315. [PMID: 30227659] - Sook Chin Chew, Chin Ping Tan, Kar Lin Nyam. Effect of Gum Arabic, β-Cyclodextrin, and Sodium Caseinate as Encapsulating Agent on the Oxidative Stability and Bioactive Compounds of Spray-Dried Kenaf Seed Oil.
Journal of food science.
2018 Sep; 83(9):2288-2294. doi:
10.1111/1750-3841.14291. [PMID: 30074623] - Chwan-Li Shen, Gurvinder Kaur, Desiree Wanders, Shaligram Sharma, Michael D Tomison, Latha Ramalingam, Eunhee Chung, Naima Moustaid-Moussa, Huanbiao Mo, Jannette M Dufour. Annatto-extracted tocotrienols improve glucose homeostasis and bone properties in high-fat diet-induced type 2 diabetic mice by decreasing the inflammatory response.
Scientific reports.
2018 07; 8(1):11377. doi:
10.1038/s41598-018-29063-9. [PMID: 30054493] - Faizul Jaafar, Asmaa Abdullah, Suzana Makpol. Cellular Uptake and Bioavailability of Tocotrienol-Rich Fraction in SIRT1-Inhibited Human Diploid Fibroblasts.
Scientific reports.
2018 Jul; 8(1):10471. doi:
10.1038/s41598-018-28708-z. [PMID: 29992988] - Heaji Lee, Yunsook Lim. Tocotrienol-rich fraction supplementation reduces hyperglycemia-induced skeletal muscle damage through regulation of insulin signaling and oxidative stress in type 2 diabetic mice.
The Journal of nutritional biochemistry.
2018 07; 57(?):77-85. doi:
10.1016/j.jnutbio.2018.03.016. [PMID: 29679925] - Nur-Vaizura Mohamad, Ima-Nirwana Soelaiman, Kok-Yong Chin. Effects of tocotrienol from Bixa orellana (annatto) on bone histomorphometry in a male osteoporosis model induced by buserelin.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
2018 Jul; 103(?):453-462. doi:
10.1016/j.biopha.2018.04.083. [PMID: 29674281]