4-(Dimethylamino)phenol (BioDeep_00001871470)

   


代谢物信息卡片


4-(Dimethylamino)phenol

化学式: C8H11NO (137.0841)
中文名称: 4-二甲氨基苯酚
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CN(C)C1=CC=C(C=C1)O
InChI: InChI=1S/C8H11NO/c1-9(2)7-3-5-8(10)6-4-7/h3-6,10H,1-2H3

描述信息

V - Various > V03 - All other therapeutic products > V03A - All other therapeutic products > V03AB - Antidotes
D020011 - Protective Agents > D000931 - Antidotes

同义名列表

1 个代谢物同义名

4-(Dimethylamino)phenol



数据库引用编号

5 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表


文献列表

  • Zeynep Aydoğmuş, Ferhat Sarı, Sevgi Tatar Ulu. Spectrofluorimetric determination of aliskiren in tablets and spiked human plasma through derivatization with dansyl chloride. Journal of fluorescence. 2012 Mar; 22(2):549-56. doi: 10.1007/s10895-011-0988-y. [PMID: 21953437]
  • Darren M Roberts, Renate Heilmair, Nick A Buckley, Andrew H Dawson, Mohamed Fahim, Michael Eddleston, Peter Eyer. Clinical outcomes and kinetics of propanil following acute self-poisoning: a prospective case series. BMC clinical pharmacology. 2009 Feb; 9(?):3. doi: 10.1186/1472-6904-9-3. [PMID: 19220887]
  • R Bhattacharya, S C Pant, D Kumar, S N Dube. Toxicity evaluation of two treatment regimens for cyanide poisoning. Journal of applied toxicology : JAT. 1995 Nov; 15(6):439-41. doi: 10.1002/jat.2550150604. [PMID: 8603930]
  • R Bhattacharya. Therapeutic efficacy of sodium nitrite and 4-dimethylaminophenol or hydroxylamine co-administration against cyanide poisoning in rats. Human & experimental toxicology. 1995 Jan; 14(1):29-33. doi: 10.1177/096032719501400107. [PMID: 7748613]
  • K G Eckert, F R Elbers, P Eyer. Depletion of mitochondrial coenzyme A and glutathione by 4-dimethylaminophenol and formation of mixed thioethers. Biochemical pharmacology. 1989 Oct; 38(19):3253-9. doi: 10.1016/0006-2952(89)90622-9. [PMID: 2818625]
  • L Szinicz. [Nephrotoxicity of aminophenols. Effect of 4-dimethylaminophenol on isolated kidney tubules in the rat]. Fortschritte der Medizin. 1984 Dec; 102(47-48):1206-8. doi: NULL. [PMID: 6519625]
  • T C Marrs, J Scawin, D W Swanston. The acute intravenous and oral toxicity in mice, rats and guinea-pigs of 4-dimethylaminophenol (DMAP) and its effects on haematological variables. Toxicology. 1984 May; 31(2):165-73. doi: 10.1016/0300-483x(84)90008-8. [PMID: 6740692]
  • R Klimmek, C Krettek, L Szinicz, P Eyer, N Weger. Effects and biotransformation of 4-dimethylaminophenol in man and dog. Archives of toxicology. 1983 Aug; 53(4):275-88. doi: 10.1007/bf00294993. [PMID: 6639349]
  • T C Marrs, J E Bright, D W Swanston. Acute oral toxicity of 4-dimethylaminophenol to the gastrointestinal tract, liver and kidney of the rat. Archives of toxicology. 1982 May; 50(1):89-92. doi: 10.1007/bf00569241. [PMID: 7115083]
  • P Jancso, L Szinicz, P Eyer. Biotransformation of 4-dimethylaminophenol in man. Archives of toxicology. 1981 Mar; 47(1):39-45. doi: 10.1007/bf00297128. [PMID: 7283738]
  • R Elbers, P Eyer, H Kampffmeyer, S Soboll. Organ toxicity and metabolic pathway of 4-dimethylaminophenol. Advances in experimental medicine and biology. 1981; 136 Pt A(?):419-29. doi: 10.1007/978-1-4757-0674-1_30. [PMID: 7344472]
  • L L Szinicz, N Weger. Effects of 4-dimethylaminophenol in rat kidneys, isolated rat kidney tubules and hepatocytes. Xenobiotica; the fate of foreign compounds in biological systems. 1980 Jul; 10(7-8):611-20. doi: 10.3109/00498258009033795. [PMID: 7445527]
  • R Elbers, H G Kampffmeyer, H Rabes. Effects and metabolic pathway of 4-dimethylaminophenol during kidney perfusion. Xenobiotica; the fate of foreign compounds in biological systems. 1980 Jul; 10(7-8):621-32. doi: 10.3109/00498258009033796. [PMID: 7445528]
  • R Klimmek, H Fladerer, N Weger. Circulation, respiration, and blood homeostasis in cyanide-poisoned dogs after treatment with 4-dimethylaminophenol or cobalt compounds. Archives of toxicology. 1979 Dec; 43(2):121-33. doi: 10.1007/bf00333619. [PMID: 119519]
  • L Szinicz, N Weger, W Schneiderhan, M Kiese. Nephrotoxicity of aminophenols: effects of 4-dimethylaminophenol on isolated rat kidney tubules. Archives of toxicology. 1979 Apr; 42(1):63-73. doi: 10.1007/bf00351825. [PMID: 454186]