2,4-Thiazolidinedione (BioDeep_00001871370)
代谢物信息卡片
2,4-Thiazolidinedione
化学式: C3H3NO2S (116.9884498)
中文名称: 2,4-噻唑烷二酮
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1C(=O)NC(=O)S1
InChI: InChI=1S/C3H3NO2S/c5-2-1-7-3(6)4-2/h1H2,(H,4,5,6)
数据库引用编号
分类词条
相关代谢途径
Reactome(0)
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代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
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0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Xinyi Zhang, Yuan Gao, Keyun Tang, Zongyu Li, Alexandra A Halberstam, Liqun Zhou, Rachel J Perry. Thiazolidinedione enhances the efficacy of anti-PD-1 monoclonal antibody in murine melanoma.
American journal of physiology. Endocrinology and metabolism.
2024 Mar; 326(3):E341-E350. doi:
10.1152/ajpendo.00346.2023. [PMID: 38294697] - Lim Shern Kwok, Shim Siang Yian, Layla Qasim Ismael, Yvonne Tee Get Bee, Gam Lay Harn, Khoo Boon Yin. Vimentin protein is a factor for decreasing breast cancer cell proliferation co-culture with human bone marrow-derived mesenchymal stem cells pre-treated with thiazolidinedione solutions.
Molecular biology reports.
2024 Feb; 51(1):317. doi:
10.1007/s11033-024-09269-z. [PMID: 38381204] - Rozh Q Ameen, Zahra A Amin, Hiwa O Ahmad, Diler D Ghafur, Melodya G Toma, Nyan Sabah, Muhammad Fakhir, Gardoon Abdulla. Gastroprotective effect of rhodanine and 2,4-thiazolidinediones scaffolds in rat stomachs by contribution of anti-apoptotic (BCL-2) and tumor suppressor (P53) proteins.
Scientific reports.
2024 01; 14(1):1699. doi:
10.1038/s41598-024-51446-4. [PMID: 38242960] - Yuanbo Qi, Mingyao Hu, Yang Qiu, Luyu Zhang, Yongchuang Yan, Yi Feng, Chenghao Feng, Xinyue Hou, Zhigang Wang, Di Zhang, Jie Zhao. Mitoglitazone ameliorates renal ischemia/reperfusion injury by inhibiting ferroptosis via targeting mitoNEET.
Toxicology and applied pharmacology.
2023 Mar; ?(?):116440. doi:
10.1016/j.taap.2023.116440. [PMID: 36870574] - Shashank R Joshi, Saibal Das, Suja Xaviar, Shambo Samrat Samajdar, Indranil Saha, Sougata Sarkar, Shatavisa Mukherjee, Santanu Kumar Tripathi, Jyotirmoy Pal, Nandini Chatterjee. Efficacy and safety of lobeglitazone, a new Thiazolidinedione, as compared to the standard of care in type 2 diabetes mellitus: A systematic review and meta-analysis.
Diabetes & metabolic syndrome.
2023 Jan; 17(1):102703. doi:
10.1016/j.dsx.2022.102703. [PMID: 36634469] - Chris E Shannon, Mukundan Ragavan, Juan Pablo Palavicini, Marcel Fourcaudot, Terry M Bakewell, Ivan A Valdez, Iriscilla Ayala, Eunsook S Jin, Muniswamy Madesh, Xianlin Han, Matthew E Merritt, Luke Norton. Insulin resistance is mechanistically linked to hepatic mitochondrial remodeling in non-alcoholic fatty liver disease.
Molecular metabolism.
2021 03; 45(?):101154. doi:
10.1016/j.molmet.2020.101154. [PMID: 33359401] - Chia-Yu Tsai, Fernanda Rosa, Massimo Bionaz, Pedram Rezamand. Effects of 2,4-thiazolidinedione (TZD) on milk fatty acid profile and serum vitamins in dairy goats challenged with intramammary infusion of Streptococcus uberis.
The Journal of dairy research.
2020 Nov; 87(4):416-423. doi:
10.1017/s0022029920000941. [PMID: 33168108] - Marta Monge, Cristina Fornaguera, Carme Quero, Aurora Dols-Perez, Gabriela Calderó, Santiago Grijalvo, María José García-Celma, Carlos Rodríguez-Abreu, Conxita Solans. Functionalized PLGA nanoparticles prepared by nano-emulsion templating interact selectively with proteins involved in the transport through the blood-brain barrier.
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2019 Oct; 97(10):4114-4123. doi:
10.1093/jas/skz269. [PMID: 31424542] - Shankar Sengottuvelan, Ritika Uppal, Suneetha Vuppu. Validation of a sensitive simultaneous LC-MS/MS method for the quantification of novel anti-cancer thiazolidinedione and quinazolin-4-one derivatives in rat plasma and its application in a rat pharmacokinetic study.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2019 Jul; 1121(?):18-27. doi:
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International journal of molecular sciences.
2019 Jun; 20(11):. doi:
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10.1016/s2213-8587(19)30087-7. [PMID: 31047901] - Paul Crawford, Amanda J Crawford. Edema from Taking Cinnamon for Treatment of Diabetes: Similar Biochemistry and Pathophysiology to Thiazolidinedione Medications.
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European journal of medicinal chemistry.
2018 Jan; 143(?):780-791. doi:
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2017 10; 7(1):14453. doi:
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European journal of medicinal chemistry.
2017 Sep; 138(?):234-245. doi:
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10.1016/j.tox.2017.03.001. [PMID: 28263783] - Tatjana Djakovic Sekulic, Adam Smolinski. RP-HPTLC Data in Correlation Studies of a 5-Arylidene-2,4-Thiazolidinedione Derivatives.
Journal of chromatographic science.
2017 May; 55(5):564-570. doi:
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Diabetes care.
2014; 37(3):686-93. doi:
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Diabetes research and clinical practice.
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Hepatology (Baltimore, Md.).
2009 Oct; 50(4):1087-93. doi:
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Diabetes, obesity & metabolism.
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Journal of the American Society of Nephrology : JASN.
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European journal of medicinal chemistry.
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Translational research : the journal of laboratory and clinical medicine.
2008 Jun; 151(6):309-14. doi:
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American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists.
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American journal of nephrology.
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Annual review of biochemistry.
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Diabetes, obesity & metabolism.
2008 Jan; 10(1):82-90. doi:
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Diabetes, obesity & metabolism.
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The Journal of clinical endocrinology and metabolism.
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Experimental gerontology.
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Acta pharmacologica Sinica.
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The Journal of nutrition.
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