Ferric pyrophosphate (BioDeep_00001871312)
代谢物信息卡片
Ferric pyrophosphate
化学式: Fe4O21P6 (745.475549)
中文名称: 焦磷酸铁(III)
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: [O-]P(=O)([O-])OP(=O)([O-])[O-].[O-]P(=O)([O-])OP(=O)([O-])[O-].[O-]P(=O)([O-])OP(=O)([O-])[O-].[Fe+3].[Fe+3].[Fe+3].[Fe+3]
InChI: /p-12
数据库引用编号
6 个数据库交叉引用编号
- ChEBI: CHEBI:132767
- PubChem: 24877
- DrugBank: DB09147
- CAS: 312619-28-6
- CAS: 10058-44-3
- CAS: 10402-25-2
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Lingxiao Zhang, Liangying Gan, Kexin Li, Panpan Xie, Yan Tan, Gang Wei, Xiaojuan Yuan, Raymond Pratt, Yongchun Zhou, Ai-Min Hui, Yi Fang, Li Zuo, Qingshan Zheng. Ethnicity evaluation of ferric pyrophosphate citrate among Asian and Non-Asian populations: a population pharmacokinetics analysis.
European journal of clinical pharmacology.
2022 Jun; ?(?):. doi:
10.1007/s00228-022-03328-9. [PMID: 35711066] - Liangying Gan, Panpan Xie, Yan Tan, Gang Wei, Xiaojuan Yuan, Zhifei Lu, Raymond Pratt, Yongchun Zhou, Ai-Min Hui, Kexin Li, Yi Fang, Li Zuo. Pharmacokinetics and Safety of Ferric Pyrophosphate Citrate in Chinese Subjects with and without Hemodialysis-Dependent Stage 5 Chronic Kidney Disease.
Drugs in R&D.
2022 Jun; 22(2):119-129. doi:
10.1007/s40268-022-00384-5. [PMID: 35380419] - Thomas Marbury, Fred van Heuveln, Eric van der Horst, Raymond D Pratt. Pharmacokinetics and Safety of Intravenous Ferric Pyrophosphate Citrate: Equivalence to Administration via Dialysate.
Journal of clinical pharmacology.
2022 05; 62(5):681-688. doi:
10.1002/jcph.1997. [PMID: 34743348] - Frederike M D Jeroense, Christophe Zeder, Michael B Zimmermann, Isabelle Herter-Aeberli. Acute Consumption of Prebiotic Galacto-Oligosaccharides Increases Iron Absorption from Ferrous Fumarate, but not from Ferrous Sulfate and Ferric Pyrophosphate: Stable Iron Isotope Studies in Iron-Depleted Young Women.
The Journal of nutrition.
2020 09; 150(9):2391-2397. doi:
10.1093/jn/nxaa199. [PMID: 32692367] - Amanda E Bries, Richard F Hurrell, Manju B Reddy. Iron Absorption from Bouillon Fortified with Iron-Enriched Aspergillus oryzae Is Higher Than That Fortified with Ferric Pyrophosphate in Young Women.
The Journal of nutrition.
2020 05; 150(5):1109-1115. doi:
10.1093/jn/nxaa035. [PMID: 32073619] - Alessandro Pappalardo, Walter Currenti, Rossella Ponzio, Giulio Mellini, Daniela Nicolosi, Lucia Longhitano, Daniele Tibullo, Sergio Castorina, Giuseppe Palumbo. Effects of micronised microencapsulated ferric pyrophosphate supplementation in patients with advanced cancer and iron deficiency: a single-centre cohort pilot study.
Blood transfusion = Trasfusione del sangue.
2019 05; 17(3):196-199. doi:
10.2450/2019.0181-18. [PMID: 30865583] - Raymond D Pratt, Sarah Grimberg, Joshua J Zaritsky, Bradley A Warady. Pharmacokinetics of ferric pyrophosphate citrate administered via dialysate and intravenously to pediatric patients on chronic hemodialysis.
Pediatric nephrology (Berlin, Germany).
2018 11; 33(11):2151-2159. doi:
10.1007/s00467-018-4014-3. [PMID: 30003313] - Angela Fabiano, Elisa Brilli, Letizia Mattii, Lara Testai, Stefania Moscato, Valentina Citi, Germano Tarantino, Ylenia Zambito. Ex Vivo and in Vivo Study of Sucrosomial® Iron Intestinal Absorption and Bioavailability.
International journal of molecular sciences.
2018 Sep; 19(9):. doi:
10.3390/ijms19092722. [PMID: 30213039] - Abhijeet Maurya, Shivakumar H Nanjappa, Swati Honnavar, M Salwa, S Narasimha Murthy. Rapidly Dissolving Microneedle Patches for Transdermal Iron Replenishment Therapy.
Journal of pharmaceutical sciences.
2018 06; 107(6):1642-1647. doi:
10.1016/j.xphs.2018.02.011. [PMID: 29462631] - A S Laganà, L Costabile, P Filati, M Noventa, A Vitagliano, R D'Anna. Effects of micronised dispersible ferric pyrophosphate combined with alpha-lactalbumin in pregnant women affected by iron deficiency anemia: results from a prospective, double-blind, randomized controlled trial.
European review for medical and pharmacological sciences.
2018 06; 22(11):3602-3608. doi:
10.26355/eurrev_201806_15187. [PMID: 29917215] - Dominik Glinz, Rita Wegmüller, Mamadou Ouattara, Victorine G Diakité, Grant J Aaron, Lorenz Hofer, Michael B Zimmermann, Lukas G Adiossan, Jürg Utzinger, Eliézer K N'Goran, Richard F Hurrell. Iron Fortified Complementary Foods Containing a Mixture of Sodium Iron EDTA with Either Ferrous Fumarate or Ferric Pyrophosphate Reduce Iron Deficiency Anemia in 12- to 36-Month-Old Children in a Malaria Endemic Setting: A Secondary Analysis of a Cluster-Randomized Controlled Trial.
Nutrients.
2017 Jul; 9(7):. doi:
10.3390/nu9070759. [PMID: 28708072] - Arnaud Monnard, Diego Moretti, Christophe Zeder, Andreas Steingötter, Michael B Zimmermann. The effect of lipids, a lipid-rich ready-to-use therapeutic food, or a phytase on iron absorption from maize-based meals fortified with micronutrient powders.
The American journal of clinical nutrition.
2017 06; 105(6):1521-1527. doi:
10.3945/ajcn.116.142976. [PMID: 28468891] - Steven Fishbane, Hitesh H Shah. Ferric pyrophosphate citrate as an iron replacement agent for patients receiving hemodialysis.
Hemodialysis international. International Symposium on Home Hemodialysis.
2017 06; 21 Suppl 1(?):S104-S109. doi:
10.1111/hdi.12554. [PMID: 28371161] - Laura Hackl, Michael B Zimmermann, Christophe Zeder, Megan Parker, Paul W Johns, Richard F Hurrell, Diego Moretti. Iron Bioavailability from Ferric Pyrophosphate in Extruded Rice Cofortified with Zinc Sulfate Is Greater than When Cofortified with Zinc Oxide in a Human Stable Isotope Study.
The Journal of nutrition.
2017 03; 147(3):377-383. doi:
10.3945/jn.116.241778. [PMID: 28148685] - Raymond D Pratt, Dorine W Swinkels, T Alp Ikizler, Ajay Gupta. Pharmacokinetics of Ferric Pyrophosphate Citrate, a Novel Iron Salt, Administered Intravenously to Healthy Volunteers.
Journal of clinical pharmacology.
2017 03; 57(3):312-320. doi:
10.1002/jcph.819. [PMID: 27557937] - Tyler Albright, Akram Al-Makki, Rabih Kalakeche, Brian Shepler. A Review of Ferric Pyrophosphate Citrate (Triferic) Use in Hemodialysis Patients.
Clinical therapeutics.
2016 Oct; 38(10):2318-2323. doi:
10.1016/j.clinthera.2016.08.012. [PMID: 27692637] - Hitesh H Shah, Azzour D Hazzan, Steven Fishbane. Ferric Pyrophosphate Citrate: A Novel Iron Replacement Agent in Patients Undergoing Hemodialysis.
Seminars in nephrology.
2016 03; 36(2):124-9. doi:
10.1016/j.semnephrol.2016.02.007. [PMID: 27236134] - Steven N Fishbane, Ajay K Singh, Serge H Cournoyer, Kailash K Jindal, Paolo Fanti, Carrie D Guss, Vivian H Lin, Raymond D Pratt, Ajay Gupta. Ferric pyrophosphate citrate (Triferic™) administration via the dialysate maintains hemoglobin and iron balance in chronic hemodialysis patients.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.
2015 Dec; 30(12):2019-26. doi:
10.1093/ndt/gfv277. [PMID: 26175145] - Dominik Glinz, Richard F Hurrell, Mamadou Ouattara, Michael B Zimmermann, Gary M Brittenham, Lukas G Adiossan, Aurélie A Righetti, Burkhardt Seifert, Victorine G Diakité, Jürg Utzinger, Eliézer K N'Goran, Rita Wegmüller. The effect of iron-fortified complementary food and intermittent preventive treatment of malaria on anaemia in 12- to 36-month-old children: a cluster-randomised controlled trial.
Malaria journal.
2015 Sep; 14(?):347. doi:
10.1186/s12936-015-0872-3. [PMID: 26377199] - Alexandre R Lobo, Eduardo H S Gaievski, Eduardo De Carli, Eliana P Alvares, Célia Colli. Fructo-oligosaccharides and iron bioavailability in anaemic rats: the effects on iron species distribution, ferroportin-1 expression, crypt bifurcation and crypt cell proliferation in the caecum.
The British journal of nutrition.
2014 Oct; 112(8):1286-95. doi:
10.1017/s0007114514002165. [PMID: 25192308] - Francis Biville, Christophe Brézillon, Dario Giorgini, Muhamed-Kheir Taha. Pyrophosphate-mediated iron acquisition from transferrin in Neisseria meningitidis does not require TonB activity.
PloS one.
2014; 9(10):e107612. doi:
10.1371/journal.pone.0107612. [PMID: 25290693] - Bianca Visciano, Paola Nazzaro, Germano Tarantino, Alessandro Taddei, Antonio Del Rio, Giusi Rosaria Mozzillo, Eleonora Riccio, Ivana Capuano, Antonio Pisani. [Liposomial iron: a new proposal for the treatment of anaemia in chronic kidney disease].
Giornale italiano di nefrologia : organo ufficiale della Societa italiana di nefrologia.
2013 Sep; 30(5):. doi:
NULL. [PMID: 24402627] - Ceres M Della Lucia, Maria das Graças Vaz Tostes, Carlos Mário M Silveira, Lívia A Bordalo, Fabiana C Rodrigues, Helena Maria Pinheiro-Sant'Ana, Hércia S D Martino, Neuza Maria B Costa. Iron bioavailability in Wistar rats fed with fortified rice by Ultra Rice technology with or without addition of yacon flour (Smallanthus sonchifolius).
Archivos latinoamericanos de nutricion.
2013 Mar; 63(1):64-73. doi:
NULL. [PMID: 24167960] - Zhengyuan Wang, Jianqin Sun, Lu Wang, Min Zong, Yanqiu Chen, Yifan Lin, Danfeng Xu, Jingjing Jiang, Yiru Pan, Jianhua Piao, Zhenwu Huang, Xiaoguang Yang. [Effect of iron supplementation on iron deficiency anemia of childbearing age women in Shanghai].
Wei sheng yan jiu = Journal of hygiene research.
2012 Jan; 41(1):51-5. doi:
NULL. [PMID: 22443058] - Ruth Blanco-Rojo, Ana M Pérez-Granados, Laura Toxqui, Carmen González-Vizcayno, Marco A Delgado, M Pilar Vaquero. Efficacy of a microencapsulated iron pyrophosphate-fortified fruit juice: a randomised, double-blind, placebo-controlled study in Spanish iron-deficient women.
The British journal of nutrition.
2011 Jun; 105(11):1652-9. doi:
10.1017/s0007114510005490. [PMID: 21303569] - Michael B Zimmermann, Ralf Biebinger, Ines Egli, Christophe Zeder, Richard F Hurrell. Iron deficiency up-regulates iron absorption from ferrous sulphate but not ferric pyrophosphate and consequently food fortification with ferrous sulphate has relatively greater efficacy in iron-deficient individuals.
The British journal of nutrition.
2011 Apr; 105(8):1245-50. doi:
10.1017/s0007114510004903. [PMID: 21205385] - Maria Andersson, Winfried Theis, Michael B Zimmermann, Jasmin Tajeri Foman, Martin Jäkel, Guus S M J E Duchateau, Leon G J Frenken, Richard F Hurrell. Random serial sampling to evaluate efficacy of iron fortification: a randomized controlled trial of margarine fortification with ferric pyrophosphate or sodium iron edetate.
The American journal of clinical nutrition.
2010 Nov; 92(5):1094-104. doi:
10.3945/ajcn.2010.29523. [PMID: 20844068] - H N Shivakumar, Siva Ram Kiran Vaka, S Narasimha Murthy. Albumin microspheres for oral delivery of iron.
Journal of drug targeting.
2010 Jan; 18(1):36-44. doi:
10.3109/10611860903156393. [PMID: 19635031] - Lena Davidsson, Shafiqual Alam Sarker, Kazi Asif Jamil, Shamima Sultana, Richard Hurrell. Regular consumption of a complementary food fortified with ascorbic acid and ferrous fumarate or ferric pyrophosphate is as useful as ferrous sulfate in maintaining hemoglobin concentrations >105 g/L in young Bangladeshi children.
The American journal of clinical nutrition.
2009 Jun; 89(6):1815-20. doi:
10.3945/ajcn.2008.27353. [PMID: 19403640] - Santiago Navas-Carretero, Ana M Pérez-Granados, Beatriz Sarriá, M Pilar Vaquero. Iron absorption from meat pate fortified with ferric pyrophosphate in iron-deficient women.
Nutrition (Burbank, Los Angeles County, Calif.).
2009 Jan; 25(1):20-4. doi:
10.1016/j.nut.2008.07.002. [PMID: 18752926] - Maria Andersson, Prashanth Thankachan, Sumithra Muthayya, Ramakrishna B Goud, Anura V Kurpad, Richard F Hurrell, Michael B Zimmermann. Dual fortification of salt with iodine and iron: a randomized, double-blind, controlled trial of micronized ferric pyrophosphate and encapsulated ferrous fumarate in southern India.
The American journal of clinical nutrition.
2008 Nov; 88(5):1378-87. doi:
10.3945/ajcn.2008.26149. [PMID: 18996875] - Christine Hotz, Maribel Porcayo, Germán Onofre, Armando García-Guerra, Terry Elliott, Shirley Jankowski, Ted Greiner. Efficacy of iron-fortified Ultra Rice in improving the iron status of women in Mexico.
Food and nutrition bulletin.
2008 Jun; 29(2):140-9. doi:
10.1177/156482650802900208. [PMID: 18693478] - I Angeles-Agdeppa, M V Capanzana, C V C Barba, R F Florentino, K Takanashi. Efficacy of iron-fortified rice in reducing anemia among schoolchildren in the Philippines.
International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition.
2008 Mar; 78(2):74-86. doi:
10.1024/0300-9831.78.2.74. [PMID: 18791976] - S Navas-Carretero, B Sarriá, A M Pérez-Granados, S Schoppen, M Izquierdo-Pulido, M P Vaquero. A comparative study of iron bioavailability from cocoa supplemented with ferric pyrophosphate or ferrous fumarate in rats.
Annals of nutrition & metabolism.
2007; 51(3):204-7. doi:
10.1159/000104138. [PMID: 17587790] - Rita Wegmüller, Fatoumata Camara, Michael B Zimmermann, Pierre Adou, Richard F Hurrell. Salt dual-fortified with iodine and micronized ground ferric pyrophosphate affects iron status but not hemoglobin in children in Cote d'Ivoire.
The Journal of nutrition.
2006 Jul; 136(7):1814-20. doi:
10.1093/jn/136.7.1814. [PMID: 16772442] - Noboru Sakaguchi, Theertham P Rao, Katsuyasu Nakata, Hironobu Nanbu, Lekh R Juneja. Iron absorption and bioavailability in rats of micronized dispersible ferric pyrophosphate.
International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition.
2004 Jan; 74(1):3-9. doi:
10.1024/0300-9831.74.1.3. [PMID: 15060895] - T Motoya, M Miyashita, A Kawachi, K Yamada. Effects of ascorbic acid on interactions between ciprofloxacin and ferrous sulphate, sodium ferrous citrate or ferric pyrophosphate, in mice.
The Journal of pharmacy and pharmacology.
2000 Apr; 52(4):397-401. doi:
10.1211/0022357001774147. [PMID: 10813549] - A Gupta, N B Amin, A Besarab, S E Vogel, G W Divine, J Yee, J V Anandan. Dialysate iron therapy: infusion of soluble ferric pyrophosphate via the dialysate during hemodialysis.
Kidney international.
1999 May; 55(5):1891-8. doi:
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