Sodium acetate (BioDeep_00001871300)
代谢物信息卡片
化学式: C2H3NaO2 (82.0030738)
中文名称: 乙酸钠,无水, 乙酸钠
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC(=O)[O-].[Na+]
InChI: /q
描述信息
B - Blood and blood forming organs > B05 - Blood substitutes and perfusion solutions > B05X - I.v. solution additives > B05XA - Electrolyte solutions
C78275 - Agent Affecting Blood or Body Fluid > C29730 - Electrolyte Replacement Agent
同义名列表
2 个代谢物同义名
数据库引用编号
7 个数据库交叉引用编号
- ChEBI: CHEBI:32954
- PubChem: 517045
- DrugBank: DB09395
- ChEMBL: CHEMBL1354
- MeSH: Sodium Acetate
- CAS: 129085-74-1
- CAS: 127-09-3
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- Sajeesh Kappachery, Mohamed AlHosani, Tanveer Alam Khan, Sara Nouh AlKharoossi, Nemah AlMansoori, Sara Ali Saeed AlShehhi, Hamda AlMansoori, Maha AlKarbi, Shina Sasi, Sameera Karumannil, Sampath Kumar Elangovan, Iltaf Shah, Mayank Anand Gururani. Modulation of antioxidant defense and PSII components by exogenously applied acetate mitigates salinity stress in Avena sativa.
Scientific reports.
2024 01; 14(1):620. doi:
10.1038/s41598-024-51302-5
. [PMID: 38182773] - E E Besong, P J Ashonibare, T M Akhigbe, J N Obimma, R E Akhigbe. Sodium acetate abates lead-induced sexual dysfunction by upregulating testosterone-dependent eNOS/NO/cGMP signaling and activating Nrf2/HO-1 in male Wistar rat.
Naunyn-Schmiedeberg's archives of pharmacology.
2023 Sep; ?(?):. doi:
10.1007/s00210-023-02696-y
. [PMID: 37658211] - Kehinde S Olaniyi, Stephanie E Areloegbe. Alleviation of adipose-hepatic glycolipid dysregulation by acetate in experimental PCOS model is associated with NF-κB/NLRP3 repression.
Canadian journal of physiology and pharmacology.
2023 Aug; ?(?):. doi:
10.1139/cjpp-2023-0169
. [PMID: 37590975] - Weiwei Li, Mingjuan Deng, Jiahui Gong, Yichao Hou, Liang Zhao. Bidirectional Regulation of Sodium Acetate on Macrophage Activity and Its Role in Lipid Metabolism of Hepatocytes.
International journal of molecular sciences.
2023 Mar; 24(6):. doi:
10.3390/ijms24065536
. [PMID: 36982619] - Kehinde S Olaniyi, Stephanie E Areloegbe. Acetate: A therapeutic candidate against renal disorder in a rat model of polycystic ovarian syndrome.
The Journal of steroid biochemistry and molecular biology.
2023 01; 225(?):106179. doi:
10.1016/j.jsbmb.2022.106179
. [PMID: 36150640] - Hai Lin, Yalu Tang, Yingbo Dong. Construction and carbon source optimization of a microbial-plant coupled reactor for treating acid mine drainage.
Environmental science and pollution research international.
2022 Nov; 29(52):78862-78873. doi:
10.1007/s11356-022-21329-0
. [PMID: 35701696] - Ping Lü, Hui-Li Li, Yong Xu, Xiao-Xu Zheng, Zhen-Hua Huang, Cong Wang, Sheng-Jun Xu, Xu-Liang Zhuang. [Effects of Nutrients on the Growth of Microcystis aeruginosa and Bacteria in the Phycosphere].
Huan jing ke xue= Huanjing kexue.
2022 Oct; 43(10):4502-4510. doi:
10.13227/j.hjkx.202201159
. [PMID: 36224136] - Yiming Li, Weina Tian, Zhongxiang Fu, Wenqi Ye, Xinwei Zhang, Zhao Zhang, Dongzhe Sun. Mechanisms of Sodium-Acetate-Induced DHA Accumulation in a DHA-Producing Microalga, Crypthecodinium sp. SUN.
Marine drugs.
2022 Aug; 20(8):. doi:
10.3390/md20080508
. [PMID: 36005511] - Kehinde S Olaniyi, Chukwubueze L Atuma, Isaiah W Sabinari, Hadiza Mahmud, Azeezat O Saidi, Adedamola A Fafure, Lawrence A Olatunji. Acetate-mediated-obestatin modulation attenuates adipose-hepatic dysmetabolism in high fat diet-induced obese rat model.
Endocrine.
2022 06; 76(3):558-569. doi:
10.1007/s12020-022-03023-w
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Food research international (Ottawa, Ont.).
2022 Jun; 156(?):111315. doi:
10.1016/j.foodres.2022.111315
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International journal of environmental research and public health.
2022 03; 19(6):. doi:
10.3390/ijerph19063674
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BMJ open.
2022 03; 12(3):e055595. doi:
10.1136/bmjopen-2021-055595
. [PMID: 35288387] - Simon Finfer, Sharon Micallef, Naomi Hammond, Leanlove Navarra, Rinaldo Bellomo, Laurent Billot, Anthony Delaney, Martin Gallagher, David Gattas, Qiang Li, Diane Mackle, Jayanthi Mysore, Manoj Saxena, Colman Taylor, Paul Young, John Myburgh. Balanced Multielectrolyte Solution versus Saline in Critically Ill Adults.
The New England journal of medicine.
2022 03; 386(9):815-826. doi:
10.1056/nejmoa2114464
. [PMID: 35041780] - Chongjun Zhang, Qifeng Zhang, Shuangshi Dong, Dandan Zhou. Could co-substrate sodium acetate simultaneously promote Chlorella to degrade amoxicillin and produce bioresources?.
Journal of hazardous materials.
2021 09; 417(?):126147. doi:
10.1016/j.jhazmat.2021.126147
. [PMID: 34229410] - Sainath Raman, Andreas Schibler, Renate Le Marsney, Peter Trnka, Melanie Kennedy, Adrian Mattke, Kristen Gibbons, Luregn J Schlapbach. 0.9\% Sodium chloride solution versus Plasma-Lyte 148 versus compound sodium lacTate solution in children admitted to PICU-a randomized controlled trial (SPLYT-P): study protocol for an intravenous fluid therapy trial.
Trials.
2021 Jul; 22(1):427. doi:
10.1186/s13063-021-05376-5
. [PMID: 34217337] - Heather A Ballard, Nicholas E Burjek. Use of normosol and Plasma-Lyte for pediatric liver transplants.
Paediatric anaesthesia.
2021 07; 31(7):830. doi:
10.1111/pan.14198
. [PMID: 34137126] - Anran Jiao, Bing Yu, Jun He, Jie Yu, Ping Zheng, Yuheng Luo, Junqiu Luo, Hui Yan, Quyuan Wang, Huifen Wang, Xiangbing Mao, Daiwen Chen. Sodium acetate, propionate, and butyrate reduce fat accumulation in mice via modulating appetite and relevant genes.
Nutrition (Burbank, Los Angeles County, Calif.).
2021 Jul; 87-88(?):111198. doi:
10.1016/j.nut.2021.111198
. [PMID: 33761444] - C Matamoros, J Cai, A D Patterson, K J Harvatine. Comparison of the effects of short-term feeding of sodium acetate and sodium bicarbonate on milk fat production.
Journal of dairy science.
2021 Jul; 104(7):7572-7582. doi:
10.3168/jds.2020-19526
. [PMID: 33814140] - Adewumi Oluwafemi Oyabambi, Olugbenga Samuel Michael, Emmanuel Damilare Areola, Salam Babatunde Saliu, Lawrence Aderemi Olatunji. Sodium acetate ameliorated systemic and renal oxidative stress in high-fructose insulin-resistant pregnant Wistar rats.
Naunyn-Schmiedeberg's archives of pharmacology.
2021 07; 394(7):1425-1435. doi:
10.1007/s00210-021-02058-6
. [PMID: 33638027] - Kehinde S Olaniyi, Oluwatobi A Amusa, Nifesimi T Akinnagbe, Isaac O Ajadi, Mary B Ajadi, Toluwani B Agunbiade, Olugbenga S Michael. Acetate ameliorates nephrotoxicity in streptozotocin-nicotinamide-induced diabetic rats: Involvement of xanthine oxidase activity.
Cytokine.
2021 06; 142(?):155501. doi:
10.1016/j.cyto.2021.155501
. [PMID: 33775493] - A M Østergaard, A N Jørgensen, S Bøvling, N P Ekeløf, F H Mose, J N Bech. Effect of 0.9\% NaCl compared to plasma-lyte on biomarkers of kidney injury, sodium excretion and tubular transport proteins in patients undergoing primary uncemented hip replacement - a randomized trial.
BMC nephrology.
2021 03; 22(1):111. doi:
10.1186/s12882-021-02310-4
. [PMID: 33771116] - Devin N Holden, Francine H Yung, Pouya Entezami. Hypertonic saline buffered with sodium acetate for intracranial pressure management.
Clinical neurology and neurosurgery.
2021 02; 201(?):106435. doi:
10.1016/j.clineuro.2020.106435
. [PMID: 33373834] - D R Wood, R M Blome, L C Ribeiro, A J Keunen, B W Keunen, G W Smith, D L Renaud. Short communication: Effects of different blood buffers administered in electrolyte solution to grain-fed veal calves experiencing diarrhea.
Journal of dairy science.
2021 Jan; 104(1):957-962. doi:
10.3168/jds.2020-18526
. [PMID: 33189262] - Laurence Weinberg, Michael Hua-Gen Li, Leonid Churilov, Christopher Macgregor, Kent Garrett, Jade Eyles, Rinaldo Bellomo. The effects of 0.9\% saline versus Plasma-Lyte 148 on renal function as assessed by creatinine concentration in patients undergoing major surgery: A single-centre double-blinded cluster crossover trial.
PloS one.
2021; 16(5):e0251718. doi:
10.1371/journal.pone.0251718
. [PMID: 34010324] - Adewumi O Oyabambi, Kehinde S Olaniyi, Ayodele O Soladoye, Lawrence A Olatunji. Suppression of uric acid and lactate production by sodium acetate ameliorates hepatic triglyceride accumulation in fructose-insulin resistant pregnant rats.
Environmental toxicology and pharmacology.
2020 Nov; 80(?):103452. doi:
10.1016/j.etap.2020.103452
. [PMID: 32610186] - Joanna Żur, Artur Piński, Danuta Wojcieszyńska, Wojciech Smułek, Urszula Guzik. Diclofenac Degradation-Enzymes, Genetic Background and Cellular Alterations Triggered in Diclofenac-Metabolizing Strain Pseudomonas moorei KB4.
International journal of molecular sciences.
2020 Sep; 21(18):. doi:
10.3390/ijms21186786
. [PMID: 32947916] - O S Michael, C L Dibia, O A Soetan, O A Adeyanju, A L Oyewole, O O Badmus, C O Adetunji, A O Soladoye. Sodium acetate prevents nicotine-induced cardiorenal dysmetabolism through uric acid/creatine kinase-dependent pathway.
Life sciences.
2020 Sep; 257(?):118127. doi:
10.1016/j.lfs.2020.118127
. [PMID: 32707052] - Kehinde S Olaniyi, Oluwatobi A Amusa. Sodium acetate-mediated inhibition of histone deacetylase alleviates hepatic lipid dysregulation and its accompanied injury in streptozotocin-nicotinamide-induced diabetic rats.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
2020 Aug; 128(?):110226. doi:
10.1016/j.biopha.2020.110226
. [PMID: 32460191] - Tabitha Mlowoka Kayira, Hiroyuki Nakano. Antibacterial effects of plant extracts with hurdle technology against Vibrio cholerae.
FEMS microbiology letters.
2020 08; 367(16):. doi:
10.1093/femsle/fnaa119
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Journal of the American Society of Nephrology : JASN.
2020 07; 31(7):1445-1461. doi:
10.1681/asn.2019080852
. [PMID: 32482686] - Mingjuan Deng, Fang Qu, Long Chen, Chang Liu, Ming Zhang, Fazheng Ren, Huiyuan Guo, Hao Zhang, Shaoyang Ge, Chaodong Wu, Liang Zhao. SCFAs alleviated steatosis and inflammation in mice with NASH induced by MCD.
The Journal of endocrinology.
2020 06; 245(3):425-437. doi:
10.1530/joe-20-0018
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Critical care (London, England).
2020 05; 24(1):271. doi:
10.1186/s13054-020-02966-8
. [PMID: 32466768] - Michael G Collins, Magid A Fahim, Elaine M Pascoe, Kathryn B Dansie, Carmel M Hawley, Philip A Clayton, Kirsten Howard, David W Johnson, Colin J McArthur, Rachael C McConnochie, Peter F Mount, Donna Reidlinger, Laura Robison, Julie Varghese, Liza A Vergara, Laurence Weinberg, Steven J Chadban. Study Protocol for Better Evidence for Selecting Transplant Fluids (BEST-Fluids): a pragmatic, registry-based, multi-center, double-blind, randomized controlled trial evaluating the effect of intravenous fluid therapy with Plasma-Lyte 148 versus 0.9\% saline on delayed graft function in deceased donor kidney transplantation.
Trials.
2020 May; 21(1):428. doi:
10.1186/s13063-020-04359-2
. [PMID: 32450917] - Kehinde S Olaniyi, Oluwatobi A Amusa, Emmanuel D Areola, Lawrence A Olatunji. Suppression of HDAC by sodium acetate rectifies cardiac metabolic disturbance in streptozotocin-nicotinamide-induced diabetic rats.
Experimental biology and medicine (Maywood, N.J.).
2020 04; 245(7):667-676. doi:
10.1177/1535370220913847
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Infectious diseases (London, England).
2020 02; 52(2):87-96. doi:
10.1080/23744235.2019.1682188
. [PMID: 31656115] - E O Dangana, T E Omolekulo, E D Areola, K S Olaniyi, A O Soladoye, L A Olatunji. Sodium acetate protects against nicotine-induced excess hepatic lipid in male rats by suppressing xanthine oxidase activity.
Chemico-biological interactions.
2020 Jan; 316(?):108929. doi:
10.1016/j.cbi.2019.108929
. [PMID: 31857090] - Vijai Williams, Muralidharan Jayashree, Karthi Nallasamy, Devi Dayal, Amit Rawat. 0.9\% saline versus Plasma-Lyte as initial fluid in children with diabetic ketoacidosis (SPinK trial): a double-blind randomized controlled trial.
Critical care (London, England).
2020 01; 24(1):1. doi:
10.1186/s13054-019-2683-3
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PloS one.
2020; 15(12):e0227724. doi:
10.1371/journal.pone.0227724
. [PMID: 33264299] - Jinjin Zhang, Hui Zhang, Miao Liu, Yawen Lan, Huiyuan Sun, Kangsen Mai, Min Wan. Short-Chain Fatty Acids Promote Intracellular Bactericidal Activity in Head Kidney Macrophages From Turbot (Scophthalmus maximus L.) via Hypoxia Inducible Factor-1α.
Frontiers in immunology.
2020; 11(?):615536. doi:
10.3389/fimmu.2020.615536
. [PMID: 33424870] - Eduardo Henrique Bredda, Aneirson Francisco Da Silva, Messias Borges Silva, Patrícia Caroline Molgero Da Rós. Mixture design as a potential tool in modeling the effect of light wavelength on Dunaliella salina cultivation: an alternative solution to increase microalgae lipid productivity for biodiesel production.
Preparative biochemistry & biotechnology.
2020; 50(4):379-389. doi:
10.1080/10826068.2019.1697936
. [PMID: 31809236] - Guiping Gong, Xu Zhang, Tianwei Tan. Simultaneously enhanced intracellular lipogenesis and β-carotene biosynthesis of Rhodotorula glutinis by light exposure with sodium acetate as the substrate.
Bioresource technology.
2020 Jan; 295(?):122274. doi:
10.1016/j.biortech.2019.122274
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Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine.
2019 Dec; 21(4):284-86. doi:
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Transfusion clinique et biologique : journal de la Societe francaise de transfusion sanguine.
2019 Nov; 26(4):209-216. doi:
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Anaesthesia.
2019 Nov; 74(11):1374-1380. doi:
10.1111/anae.14697
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Chemistry (Weinheim an der Bergstrasse, Germany).
2019 10; 25(56):12946-12956. doi:
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Journal of photochemistry and photobiology. B, Biology.
2019 Oct; 199(?):111628. doi:
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. [PMID: 31610432] - Baohua Chai, Yi Wang, Wenhuai Wang, Pan Fan. Effect of carbon source on lipid accumulation and biodiesel production of Yarrowia lipolytica.
Environmental science and pollution research international.
2019 Oct; 26(30):31234-31242. doi:
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Food chemistry.
2019 Sep; 293(?):491-498. doi:
10.1016/j.foodchem.2019.04.119
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Forensic science international.
2019 Sep; 302(?):109936. doi:
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. [PMID: 31493923] - Zhenyao Wang, Fei Luo, Ziting Wang, Rong Zhou, Yufang Tang, Yuqin Li. The potential growth and lipid accumulation in Coccomyxa subellipsoidea triggered by glucose combining with sodium acetate.
World journal of microbiology & biotechnology.
2019 Jul; 35(7):110. doi:
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. [PMID: 31280381] - Rachel Visage, Nicole Kaiser, Megan Williams, Abby Kim. Oral Methods of Urinary Alkalinization for High-dose Methotrexate Administration: Alternatives to Intravenous Sodium Bicarbonate During a Critical Drug Shortage.
Journal of pediatric hematology/oncology.
2019 07; 41(5):371-375. doi:
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. [PMID: 30475303] - N Urrutia, R Bomberger, C Matamoros, K J Harvatine. Effect of dietary supplementation of sodium acetate and calcium butyrate on milk fat synthesis in lactating dairy cows.
Journal of dairy science.
2019 Jun; 102(6):5172-5181. doi:
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. [PMID: 30981489] - Lu Wang, Ruidong Zhang. [Effect of sodium acetate Ringer injection on perioperative fluid therapy in children with cyanotic congenital heart disease].
Zhonghua wei zhong bing ji jiu yi xue.
2019 Mar; 31(3):363-366. doi:
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Huan jing ke xue= Huanjing kexue.
2019 Feb; 40(2):783-790. doi:
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. [PMID: 30628344] - Tyler B Shubitowski, Brian G Poll, Niranjana Natarajan, Jennifer L Pluznick. Short-chain fatty acid delivery: assessing exogenous administration of the microbiome metabolite acetate in mice.
Physiological reports.
2019 02; 7(4):e14005. doi:
10.14814/phy2.14005
. [PMID: 30810289] - Rachael Dawson, Andrew Wignell, Paul Cooling, David Barrett, Harish Vyas, Patrick Davies. Physico-chemical stability of Plasma-Lyte 148® and Plasma-Lyte 148® + 5\% Glucose with eight common intravenous medications.
Paediatric anaesthesia.
2019 Feb; 29(2):186-192. doi:
10.1111/pan.13554
. [PMID: 30472805] - Tolulope Eniola Omolekulo, Olugbenga Samuel Michael, Lawrence Aderemi Olatunji. Sodium acetate improves disrupted glucoregulation and hepatic triglyceride content in insulin-resistant female rats: involvement of adenosine deaminase and dipeptidyl peptidase-4 activities.
Naunyn-Schmiedeberg's archives of pharmacology.
2019 01; 392(1):103-116. doi:
10.1007/s00210-018-1569-2
. [PMID: 30280312] - Taofeek O Usman, Emmanuel D Areola, Olufunto O Badmus, InKyeom Kim, Lawrence A Olatunji. Sodium acetate and androgen receptor blockade improve gestational androgen excess-induced deteriorated glucose homeostasis and antioxidant defenses in rats: roles of adenosine deaminase and xanthine oxidase activities.
The Journal of nutritional biochemistry.
2018 12; 62(?):65-75. doi:
10.1016/j.jnutbio.2018.08.018
. [PMID: 30267975] - Ofer Sadan, Owen Samuels, William H Asbury, John J Hanfelt, Kai Singbartl. Low-chloride versus high-chloride hypertonic solution for the treatment of subarachnoid hemorrhage-related complications (The ACETatE trial): study protocol for a pilot randomized controlled trial.
Trials.
2018 Nov; 19(1):628. doi:
10.1186/s13063-018-3007-7
. [PMID: 30428930] - Lawrence A Olatunji, Emmanuel D Areola, Olufunto O Badmus. Endoglin inhibition by sodium acetate and flutamide ameliorates cardiac defective G6PD-dependent antioxidant defense in gestational testosterone-exposed rats.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
2018 Nov; 107(?):1641-1647. doi:
10.1016/j.biopha.2018.08.133
. [PMID: 30257382] - Mari Fihlman, Janne T Kataja. Is the infusion of Plasma-Lyte 148 and 5\% Glucose into peripheral veins really problematic?.
Acta paediatrica (Oslo, Norway : 1992).
2018 11; 107(11):2026-2027. doi:
10.1111/apa.14475
. [PMID: 29953656] - Hyun-Jung Shin, Hee-Yeon Park, Hyo-Seok Na, Jung-Pyo Hong, Gwan-Woo Lee, Sang-Hwan Do. The effects of Plasma-Lyte 148 solution on blood coagulation: an in-vitro, volunteer study using rotational thromboelastometry.
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis.
2018 Jul; 29(5):446-450. doi:
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Food chemistry.
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Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine.
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World journal of microbiology & biotechnology.
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Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners.
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Plant physiology.
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Food chemistry.
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Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine.
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Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine.
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The Cochrane database of systematic reviews.
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Canadian journal of anaesthesia = Journal canadien d'anesthesie.
2016 Aug; 63(8):952-61. doi:
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Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery.
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The journal of trauma and acute care surgery.
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International journal of environmental research and public health.
2016 06; 13(6):. doi:
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Journal of immunology (Baltimore, Md. : 1950).
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Bioresource technology.
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Molecular genetics and metabolism.
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American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists.
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Applied biochemistry and biotechnology.
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Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society.
2015 Aug; 27(8):1120-6. doi:
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Acta tropica.
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