2-Keto-3-Deoxy-D-Mannooctanoic Acid (BioDeep_00001870157)

Main id: BioDeep_00000013816

 


代谢物信息卡片


2-Keto-3-Deoxy-D-Mannooctanoic Acid

化学式: C8H14O8 (238.0689)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1C(C(C(OC1(C(=O)O)O)C(CO)O)O)O
InChI: InChI=1S/C8H14O8/c9-2-4(11)6-5(12)3(10)1-8(15,16-6)7(13)14/h3-6,9-12,15H,1-2H2,(H,13,14)/t3-,4-,5-,6-,8?/m1/s1

描述信息

同义名列表

1 个代谢物同义名

2-Keto-3-Deoxy-D-Mannooctanoic Acid



数据库引用编号

6 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表


文献列表

  • Akintunde Emiola, Steven S Andrews, Carolin Heller, John George. Crosstalk between the lipopolysaccharide and phospholipid pathways during outer membrane biogenesis in Escherichia coli. Proceedings of the National Academy of Sciences of the United States of America. 2016 Mar; 113(11):3108-13. doi: 10.1073/pnas.1521168113. [PMID: 26929331]
  • Tetsuto Nakagawa, Yoshimi Shimada, Nadejda V Pavlova, Su-Chen Li, Yu-Teh Li. Cloning and expression of 3-deoxy-d-manno-oct-2-ulosonic acid α-ketoside hydrolase from oyster hepatopancreas†. Glycobiology. 2015 Dec; 25(12):1431-40. doi: 10.1093/glycob/cwv074. [PMID: 26362869]
  • Uwe Mamat, Kathleen Wilke, David Bramhill, Andra Beate Schromm, Buko Lindner, Thomas Andreas Kohl, José Luis Corchero, Antonio Villaverde, Lana Schaffer, Steven Robert Head, Chad Souvignier, Timothy Charles Meredith, Ronald Wesley Woodard. Detoxifying Escherichia coli for endotoxin-free production of recombinant proteins. Microbial cell factories. 2015 Apr; 14(?):57. doi: 10.1186/s12934-015-0241-5. [PMID: 25890161]
  • Malin Vonkavaara, Shaikh Terkis Islam Pavel, Kathrin Hölzl, Roland Nordfelth, Anders Sjöstedt, Svenja Stöven. Francisella is sensitive to insect antimicrobial peptides. Journal of innate immunity. 2013; 5(1):50-9. doi: 10.1159/000342468. [PMID: 23037919]
  • Yukari Fujimoto, Atsushi Shimoyama, Yasuo Suda, Koichi Fukase. Synthesis and immunomodulatory activities of Helicobacter pylori lipophilic terminus of lipopolysaccharide including lipid A. Carbohydrate research. 2012 Jul; 356(?):37-43. doi: 10.1016/j.carres.2012.03.013. [PMID: 22486825]
  • Ken Shiraiwa, Shen Yuan, Ayako Fujiyama, Yosuke Matsuo, Takashi Tanaka, Zhi-Hong Jiang, Isao Kouno. Benzyl benzoate glycoside and 3-deoxy-D-manno-2-octulosonic acid derivatives from Solidago decurrens. Journal of natural products. 2012 Jan; 75(1):88-92. doi: 10.1021/np2007582. [PMID: 22185651]
  • Simon Ittig, Buko Lindner, Marco Stenta, Pablo Manfredi, Evelina Zdorovenko, Yuriy A Knirel, Matteo dal Peraro, Guy R Cornelis, Ulrich Zähringer. The lipopolysaccharide from Capnocytophaga canimorsus reveals an unexpected role of the core-oligosaccharide in MD-2 binding. PLoS pathogens. 2012; 8(5):e1002667. doi: 10.1371/journal.ppat.1002667. [PMID: 22570611]
  • Masaru Kobayashi, Nagisa Kouzu, Akina Inami, Kiminori Toyooka, Yuki Konishi, Ken Matsuoka, Toru Matoh. Characterization of Arabidopsis CTP:3-deoxy-D-manno-2-octulosonate cytidylyltransferase (CMP-KDO synthetase), the enzyme that activates KDO during rhamnogalacturonan II biosynthesis. Plant & cell physiology. 2011 Oct; 52(10):1832-43. doi: 10.1093/pcp/pcr120. [PMID: 21893514]
  • Hak Suk Chung, Christian R H Raetz. Dioxygenases in Burkholderia ambifaria and Yersinia pestis that hydroxylate the outer Kdo unit of lipopolysaccharide. Proceedings of the National Academy of Sciences of the United States of America. 2011 Jan; 108(2):510-5. doi: 10.1073/pnas.1016462108. [PMID: 21178073]
  • L Cipolla, A Polissi, C Airoldi, L Gabrielli, S Merlo, F Nicotra. New targets for antibacterial design: Kdo biosynthesis and LPS machinery transport to the cell surface. Current medicinal chemistry. 2011; 18(6):830-52. doi: 10.2174/092986711794927676. [PMID: 21182480]
  • Teresa Ieranò, Alba Silipo, Evgeny L Nazarenko, Raisa P Gorshkova, Elena P Ivanova, Domenico Garozzo, Luisa Sturiale, Rosa Lanzetta, Michelangelo Parrilli, Antonio Molinaro. Against the rules: a marine bacterium, Loktanella rosea, possesses a unique lipopolysaccharide. Glycobiology. 2010 May; 20(5):586-93. doi: 10.1093/glycob/cwq008. [PMID: 20093711]
  • Gabriela Bugla-Płoskońska, Jacek Rybka, Bozena Futoma-Kołoch, Agnieszka Cisowska, Andrzej Gamian, Włodzimierz Doroszkiewicz. Sialic acid-containing lipopolysaccharides of Salmonella O48 strains--potential role in camouflage and susceptibility to the bactericidal effect of normal human serum. Microbial ecology. 2010 Apr; 59(3):601-13. doi: 10.1007/s00248-009-9600-2. [PMID: 19844648]
  • Silvia Sommaruga, Luca De Gioia, Paolo Tortora, Alessandra Polissi. Structure prediction and functional analysis of KdsD, an enzyme involved in lipopolysaccharide biosynthesis. Biochemical and biophysical research communications. 2009 Oct; 388(2):222-7. doi: 10.1016/j.bbrc.2009.07.154. [PMID: 19664604]
  • Cory L Brooks, Sven Müller-Loennies, Lore Brade, Paul Kosma, Tomoko Hirama, C Roger MacKenzie, Helmut Brade, Stephen V Evans. Exploration of specificity in germline monoclonal antibody recognition of a range of natural and synthetic epitopes. Journal of molecular biology. 2008 Mar; 377(2):450-68. doi: 10.1016/j.jmb.2008.01.018. [PMID: 18272175]
  • Uwe Mamat, Timothy C Meredith, Parag Aggarwal, Annika Kühl, Paul Kirchhoff, Buko Lindner, Anna Hanuszkiewicz, Jennifer Sun, Otto Holst, Ronald W Woodard. Single amino acid substitutions in either YhjD or MsbA confer viability to 3-deoxy-d-manno-oct-2-ulosonic acid-depleted Escherichia coli. Molecular microbiology. 2008 Feb; 67(3):633-48. doi: 10.1111/j.1365-2958.2007.06074.x. [PMID: 18093093]
  • Hamid Hakimi, Ian Geary, Allan Pacey, Adrian Eley. Spermicidal activity of bacterial lipopolysaccharide is only partly due to lipid A. Journal of andrology. 2006 Nov; 27(6):774-9. doi: 10.2164/jandrol.106.000083. [PMID: 16809274]
  • Jolanta Lukasiewicz, Tomasz Niedziela, Wojciech Jachymek, Lennart Kenne, Czeslaw Lugowski. Structure of the lipid A-inner core region and biological activity of Plesiomonas shigelloides O54 (strain CNCTC 113/92) lipopolysaccharide. Glycobiology. 2006 Jun; 16(6):538-50. doi: 10.1093/glycob/cwj094. [PMID: 16490765]
  • N Fraysse, B Lindner, Z Kaczynski, L Sharypova, O Holst, K Niehaus, V Poinsot. Sinorhizobium meliloti strain 1021 produces a low-molecular-mass capsular polysaccharide that is a homopolymer of 3-deoxy-D-manno-oct-2-ulosonic acid harboring a phospholipid anchor. Glycobiology. 2005 Jan; 15(1):101-8. doi: 10.1093/glycob/cwh142. [PMID: 15355932]
  • Nicole R Luke, Simon Allen, Bradford W Gibson, Anthony A Campagnari. Identification of a 3-deoxy-D-manno-octulosonic acid biosynthetic operon in Moraxella catarrhalis and analysis of a KdsA-deficient isogenic mutant. Infection and immunity. 2003 Nov; 71(11):6426-34. doi: 10.1128/iai.71.11.6426-6434.2003. [PMID: 14573664]
  • S N Chatterjee, Keya Chaudhuri. Lipopolysaccharides of Vibrio cholerae. I. Physical and chemical characterization. Biochimica et biophysica acta. 2003 Oct; 1639(2):65-79. doi: 10.1016/j.bbadis.2003.08.004. [PMID: 14559113]
  • M M Olsthoorn, J Haverkamp, J E Thomas-Oates. Mass spectrometric analysis of Klebsiella pneumoniae ssp. pneumoniae rough strain R20 (O1-: K20-) lipopolysaccharide preparations: identification of novel core oligosaccharide components and three 3-deoxy-D-manno-oct-2-ulopyranosonic artifacts. Journal of mass spectrometry : JMS. 1999 Jun; 34(6):622-36. doi: 10.1002/(sici)1096-9888(199906)34:6<622::aid-jms814>3.0.co;2-v. [PMID: 10394628]
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