Tricaine (BioDeep_00001868532)
Main id: BioDeep_00000012067
代谢物信息卡片
Tricaine
化学式: C9H11NO2 (165.0789746)
中文名称: 3-氨基苯甲酸乙酯
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CCOC(=O)C1=CC(=CC=C1)N
InChI: InChI=1S/C9H11NO2/c1-2-12-9(11)7-4-3-5-8(10)6-7/h3-6H,2,10H2,1H3
描述信息
D002491 - Central Nervous System Agents > D002492 - Central Nervous System Depressants > D000777 - Anesthetics
C78272 - Agent Affecting Nervous System > C245 - Anesthetic Agent
同义名列表
1 个代谢物同义名
数据库引用编号
9 个数据库交叉引用编号
- ChEBI: CHEBI:81494
- KEGG: C18090
- PubChem: 11400
- DrugBank: DB11552
- ChEMBL: CHEMBL1702228
- CAS: 582-33-2
- PubChem: 96024307
- PDB-CCD: FG7
- NIKKAJI: J47.824E
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- T Rairat, Y Chi, S-K Chang, C-Y Hsieh, N Chuchird, C-C Chou. Differential effects of aquatic anaesthetics on the pharmacokinetics of antibiotics: Examples using florfenicol in Nile tilapia (Oreochromis niloticus).
Journal of fish diseases.
2021 Oct; 44(10):1579-1586. doi:
10.1111/jfd.13480. [PMID: 34152617] - Michael J Venincasa, Owen Randlett, Sureni H Sumathipala, Richard Bindernagel, Matthew J Stark, Qing Yan, Steven A Sloan, Elena Buglo, Qing Cheng Meng, Florian Engert, Stephan Züchner, Max B Kelz, Sheyum Syed, Julia E Dallman. Elevated preoptic brain activity in zebrafish glial glycine transporter mutants is linked to lethargy-like behaviors and delayed emergence from anesthesia.
Scientific reports.
2021 02; 11(1):3148. doi:
10.1038/s41598-021-82342-w. [PMID: 33542258] - Nathalia Dos Santos Teixeira, Lis Santos Marques, Rômulo Batista Rodrigues, Darlan Gusso, Gabriela Thais Pinheiro, Thales Lysakowski Flores Machado, Danilo Pedro Streit. Effects of anesthetic MS-222 on stress and reproduction of South American silver catfish (Rhamdia quelen) males.
Animal reproduction science.
2021 Feb; 225(?):106669. doi:
10.1016/j.anireprosci.2020.106669. [PMID: 33360163] - Rachel J Chance, Gary A Cameron, Mark Fordyce, Patricia Noguera, Tiehui Wang, Catherine Collins, Christopher J Secombes, Bertrand Collet. Effects of repeated anaesthesia on gill and general health of Atlantic salmon, Salmo salar.
Journal of fish biology.
2018 Dec; 93(6):1069-1081. doi:
10.1111/jfb.13803. [PMID: 30242832] - Briony D Smith, Krystal J Vail, Gwendolyn L Carroll, Maggie C Taylor, Nicholas D Jeffery, Tracy H Vemulapalli, James J Elliott. Comparison of Etomidate, Benzocaine, and MS222 Anesthesia with and without Subsequent Flunixin Meglumine Analgesia in African Clawed Frogs (Xenopus laevis).
Journal of the American Association for Laboratory Animal Science : JAALAS.
2018 03; 57(2):202-209. doi:
NULL. [PMID: 29555009] - K F Larter, B B Rees. Influence of euthanasia method on blood and gill variables in normoxic and hypoxic Gulf killifish Fundulus grandis.
Journal of fish biology.
2017 Jun; 90(6):2323-2343. doi:
10.1111/jfb.13316. [PMID: 28397260] - Giovanna R Stringhetta, Luis A L Barbas, Lucas C Maltez, Luís A Sampaio, José M Monserrat, Luciano O Garcia. Oxidative stress responses of juvenile tambaqui Colossoma macropomum after short-term anesthesia with benzocaine and MS-222.
Anais da Academia Brasileira de Ciencias.
2017; 89(3 Suppl):2209-2218. doi:
10.1590/0001-3765201720160823. [PMID: 28746612] - Daniel J Davis, Jenna Klug, Miriam Hankins, Holly M Doerr, Stephanie R Monticelli, Ava Song, Catherine H Gillespie, Elizabeth C Bryda. Effects of Clove Oil as a Euthanasia Agent on Blood Collection Efficiency and Serum Cortisol Levels in Danio rerio.
Journal of the American Association for Laboratory Animal Science : JAALAS.
2015 Sep; 54(5):564-7. doi:
NULL. [PMID: 26424256] - L M Vera, A Montoya, F J Sánchez-Vázquez. Effectiveness of the anaesthetic MS-222 in gilthead seabream, Sparus aurata: effect of feeding time and day-night variations in plasma MS-222 concentration and GST activity.
Physiology & behavior.
2013 Feb; 110-111(?):51-7. doi:
10.1016/j.physbeh.2012.12.012. [PMID: 23291569] - H Gholipour Kanani, M Soltani, S S Mirzargar. Effect of tricainemethanesulfonate (MS222), clove oil and electro-anaesthesia on respiratory burst activity in whole blood and serum alternative complement response in rainbow trout (Oncorhynchus mykiss), during the narcosis stage.
Fish & shellfish immunology.
2013 Feb; 34(2):692-6. doi:
10.1016/j.fsi.2012.11.021. [PMID: 23220716] - Sandra E Hernández, Conrad Sernia, Adrian J Bradley. The effect of three anaesthetic protocols on the stress response in cane toads (Rhinella marina).
Veterinary anaesthesia and analgesia.
2012 Nov; 39(6):584-90. doi:
10.1111/j.1467-2995.2012.00753.x. [PMID: 22765650] - Vanessa Lalonde-Robert, Francis Beaudry, Pascal Vachon. Pharmacologic parameters of MS222 and physiologic changes in frogs (Xenopus laevis) after immersion at anesthetic doses.
Journal of the American Association for Laboratory Animal Science : JAALAS.
2012 Jul; 51(4):464-8. doi:
NULL. [PMID: 23043812] - Simon Bulling, Klaus Schicker, Yuan-Wei Zhang, Thomas Steinkellner, Thomas Stockner, Christian W Gruber, Stefan Boehm, Michael Freissmuth, Gary Rudnick, Harald H Sitte, Walter Sandtner. The mechanistic basis for noncompetitive ibogaine inhibition of serotonin and dopamine transporters.
The Journal of biological chemistry.
2012 May; 287(22):18524-34. doi:
10.1074/jbc.m112.343681. [PMID: 22451652] - Christopher Sauvage, Marie Vagner, Nicolas Derôme, Céline Audet, Louis Bernatchez. Coding Gene Single Nucleotide Polymorphism Mapping and Quantitative Trait Loci Detection for Physiological Reproductive Traits in Brook Charr, Salvelinus fontinalis.
G3 (Bethesda, Md.).
2012 Mar; 2(3):379-92. doi:
10.1534/g3.111.001867. [PMID: 22413092] - Mark J Airhart, Deborah H Lee, Tracy D Wilson, Barney E Miller, Merry N Miller, Richard G Skalko, Paul J Monaco. Adverse effects of serotonin depletion in developing zebrafish.
Neurotoxicology and teratology.
2012 Jan; 34(1):152-60. doi:
10.1016/j.ntt.2011.08.008. [PMID: 21893190] - Ji Sun Baek, Longhou Fang, Andrew C Li, Yury I Miller. Ezetimibe and simvastatin reduce cholesterol levels in zebrafish larvae fed a high-cholesterol diet.
Cholesterol.
2012; 2012(?):564705. doi:
10.1155/2012/564705. [PMID: 22693663] - Ruxandra Bachmann-Gagescu, Ian G Phelps, George Stearns, Brian A Link, Susan E Brockerhoff, Cecilia B Moens, Dan Doherty. The ciliopathy gene cc2d2a controls zebrafish photoreceptor outer segment development through a role in Rab8-dependent vesicle trafficking.
Human molecular genetics.
2011 Oct; 20(20):4041-55. doi:
10.1093/hmg/ddr332. [PMID: 21816947] - Corbin S Johnson, Nicholas F Holzemer, Rebecca A Wingert. Laser ablation of the zebrafish pronephros to study renal epithelial regeneration.
Journal of visualized experiments : JoVE.
2011 Aug; ?(54):. doi:
10.3791/2845. [PMID: 21897358] - Gary F Gerlach, Lauran N Schrader, Rebecca A Wingert. Dissection of the adult zebrafish kidney.
Journal of visualized experiments : JoVE.
2011 Aug; ?(54):. doi:
10.3791/2839. [PMID: 21897357] - Cuong Q Diep, Alan J Davidson. Transplantation of cells directly into the kidney of adult zebrafish.
Journal of visualized experiments : JoVE.
2011 May; ?(51):. doi:
10.3791/2725. [PMID: 21633330] - Seok-Hyung Kim, Christina K Speirs, Lilianna Solnica-Krezel, Kevin C Ess. Zebrafish model of tuberous sclerosis complex reveals cell-autonomous and non-cell-autonomous functions of mutant tuberin.
Disease models & mechanisms.
2011 Mar; 4(2):255-67. doi:
10.1242/dmm.005587. [PMID: 20959633] - Christopher P Cutler, Bryce Maciver, Gordon Cramb, Mark Zeidel. Aquaporin 4 is a Ubiquitously Expressed Isoform in the Dogfish (Squalus acanthias) Shark.
Frontiers in physiology.
2011; 2(?):107. doi:
10.3389/fphys.2011.00107. [PMID: 22291652] - James Rae, Frank Fontaine, Angela A Salim, Harriet P Lo, Robert J Capon, Robert G Parton, Sally Martin. High-throughput screening of Australian marine organism extracts for bioactive molecules affecting the cellular storage of neutral lipids.
PloS one.
2011; 6(8):e22868. doi:
10.1371/journal.pone.0022868. [PMID: 21857959] - Vernat J Exil, Daiana Silva Avila, Alexandre Benedetto, Elizabeth A Exil, Margaret R Adams, Catherine Au, Michael Aschner. Stressed-induced TMEM135 protein is part of a conserved genetic network involved in fat storage and longevity regulation in Caenorhabditis elegans.
PloS one.
2010 Dec; 5(12):e14228. doi:
10.1371/journal.pone.0014228. [PMID: 21151927] - Paraskevi Krashia, Mirko Moroni, Steven Broadbent, Giovanna Hofmann, Sebastian Kracun, Marco Beato, Paul J Groot-Kormelink, Lucia G Sivilotti. Human α3β4 neuronal nicotinic receptors show different stoichiometry if they are expressed in Xenopus oocytes or mammalian HEK293 cells.
PloS one.
2010 Oct; 5(10):e13611. doi:
10.1371/journal.pone.0013611. [PMID: 21049012] - Sharon Ashworth, Beina Teng, Jessica Kaufeld, Emily Miller, Irini Tossidou, Christoph Englert, Frank Bollig, Lynne Staggs, Ian S D Roberts, Joon-Keun Park, Hermann Haller, Mario Schiffer. Cofilin-1 inactivation leads to proteinuria--studies in zebrafish, mice and humans.
PloS one.
2010 Sep; 5(9):e12626. doi:
10.1371/journal.pone.0012626. [PMID: 20838616] - George Zanazzi, Gary Matthews. Enrichment and differential targeting of complexins 3 and 4 in ribbon-containing sensory neurons during zebrafish development.
Neural development.
2010 Sep; 5(?):24. doi:
10.1186/1749-8104-5-24. [PMID: 20809954] - Chiara Cianciolo Cosentino, Beth L Roman, Iain A Drummond, Neil A Hukriede. Intravenous microinjections of zebrafish larvae to study acute kidney injury.
Journal of visualized experiments : JoVE.
2010 Aug; ?(42):. doi:
10.3791/2079. [PMID: 20729805] - Oliana Carnevali, Luca Tosti, Claudia Speciale, Chun Peng, Yong Zhu, Francesca Maradonna. DEHP impairs zebrafish reproduction by affecting critical factors in oogenesis.
PloS one.
2010 Apr; 5(4):e10201. doi:
10.1371/journal.pone.0010201. [PMID: 20419165] - Tripti Gupta, Mary C Mullins. Dissection of organs from the adult zebrafish.
Journal of visualized experiments : JoVE.
2010 Mar; ?(37):. doi:
10.3791/1717. [PMID: 20203557] - Christian P Preuss, Chun Y Huang, Matthew Gilliham, Stephen D Tyerman. Channel-like characteristics of the low-affinity barley phosphate transporter PHT1;6 when expressed in Xenopus oocytes.
Plant physiology.
2010 Mar; 152(3):1431-41. doi:
10.1104/pp.109.152009. [PMID: 20053709] - Kevin W Wanner, Andrew S Nichols, Jean E Allen, Peggy L Bunger, Stephen F Garczynski, Charles E Linn, Hugh M Robertson, Charles W Luetje. Sex pheromone receptor specificity in the European corn borer moth, Ostrinia nubilalis.
PloS one.
2010 Jan; 5(1):e8685. doi:
10.1371/journal.pone.0008685. [PMID: 20084285] - Aner Gurvitz. A C. elegans model for mitochondrial fatty acid synthase II: the longevity-associated gene W09H1.5/mecr-1 encodes a 2-trans-enoyl-thioester reductase.
PloS one.
2009 Nov; 4(11):e7791. doi:
10.1371/journal.pone.0007791. [PMID: 19924289] - Dan Li, Abbas Raza, Jeff DeJong. Regulation of ALF promoter activity in Xenopus oocytes.
PloS one.
2009 Aug; 4(8):e6664. doi:
10.1371/journal.pone.0006664. [PMID: 19684851] - Rose L Szabady, Mary A Lokuta, Kevin B Walters, Anna Huttenlocher, Rodney A Welch. Modulation of neutrophil function by a secreted mucinase of Escherichia coli O157:H7.
PLoS pathogens.
2009 Feb; 5(2):e1000320. doi:
10.1371/journal.ppat.1000320. [PMID: 19247439] - James J Dowling, Andrew P Vreede, Sean E Low, Elizabeth M Gibbs, John Y Kuwada, Carsten G Bonnemann, Eva L Feldman. Loss of myotubularin function results in T-tubule disorganization in zebrafish and human myotubular myopathy.
PLoS genetics.
2009 Feb; 5(2):e1000372. doi:
10.1371/journal.pgen.1000372. [PMID: 19197364] - Aleksandr Vasilyev, Yan Liu, Sudha Mudumana, Steve Mangos, Pui-Ying Lam, Arindam Majumdar, Jinhua Zhao, Kar-Lai Poon, Igor Kondrychyn, Vladimir Korzh, Iain A Drummond. Collective cell migration drives morphogenesis of the kidney nephron.
PLoS biology.
2009 Jan; 7(1):e9. doi:
10.1371/journal.pbio.1000009. [PMID: 19127979] - Neil C Chi, Robin M Shaw, Benno Jungblut, Jan Huisken, Tania Ferrer, Rima Arnaout, Ian Scott, Dimitris Beis, Tong Xiao, Herwig Baier, Lily Y Jan, Martin Tristani-Firouzi, Didier Y R Stainier. Genetic and physiologic dissection of the vertebrate cardiac conduction system.
PLoS biology.
2008 May; 6(5):e109. doi:
10.1371/journal.pbio.0060109. [PMID: 18479184] - L Song, T Kitayama, K Morita, N Morioka, T Dohi. Down-regulation of norepinephrine transporter expression on membrane surface induced by chronic administration of desipramine and the antagonism by co-administration of local anesthetics in mice.
Neurochemistry international.
2008 Mar; 52(4-5):826-33. doi:
10.1016/j.neuint.2007.09.013. [PMID: 17981365] - Pål A Olsvik, Kai K Lie, Ernst M Hevrøy. Do anesthetics and sampling strategies affect transcription analysis of fish tissues?.
BMC molecular biology.
2007 Jun; 8(?):48. doi:
10.1186/1471-2199-8-48. [PMID: 17559653] - Simon MacKenzie, Nuria Montserrat, Mario Mas, Laura Acerete, Lluis Tort, Aleksei Krasnov, Frederick W Goetz, Josep V Planas. Bacterial lipopolysaccharide induces apoptosis in the trout ovary.
Reproductive biology and endocrinology : RB&E.
2006 Aug; 4(?):46. doi:
10.1186/1477-7827-4-46. [PMID: 16945135] - Tomoya Kitayama, Liqiu Song, Katsuya Morita, Norimitsu Morioka, Toshihiro Dohi. Down-regulation of norepinephrine transporter function induced by chronic administration of desipramine linking to the alteration of sensitivity of local-anesthetics-induced convulsions and the counteraction by co-administration with local anesthetics.
Brain research.
2006 Jun; 1096(1):97-103. doi:
10.1016/j.brainres.2006.04.033. [PMID: 16725121] - Dusan Palić, Claire B Andreasen, Bruce W Menzel, James A Roth. A rapid, direct assay to measure degranulation of primary granules in neutrophils from kidney of fathead minnow (Pimephales promelas Rafinesque, 1820).
Fish & shellfish immunology.
2005 Sep; 19(3):217-27. doi:
10.1016/j.fsi.2004.12.003. [PMID: 15820123] - Craig A Harms, Gregory A Lewbart, Clifford R Swanson, Jennifer M Kishimori, Shane M Boylan. Behavioral and clinical pathology changes in koi carp (Cyprinus carpio) subjected to anesthesia and surgery with and without intra-operative analgesics.
Comparative medicine.
2005 Jun; 55(3):221-6. doi:
. [PMID: 16089168] - S M Plakas, G R Stehly, L Khoo. Pharmacokinetics and excretion of phenol red in the channel catfish.
Xenobiotica; the fate of foreign compounds in biological systems.
1992 May; 22(5):551-7. doi:
10.3109/00498259209053118. [PMID: 1413870] - S Ryan. The dynamics of MS-222 anaesthesia in a marine teleost (Pagrus auratus: Sparidae).
Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology.
1992 Apr; 101(3):593-600. doi:
10.1016/0742-8413(92)90092-l. [PMID: 1354139] - A J Harrington, K A Russell, T D Singer, J S Ballantyne. The effects of tricaine methanesulfonate (MS-222) on plasma nonesterified fatty acids in rainbow trout, Oncorhynchus mykiss.
Lipids.
1991 Sep; 26(9):774-5. doi:
10.1007/bf02535630. [PMID: 1762525] - W H Gingerich, K R Drottar. Plasma catecholamine concentrations in rainbow trout (Salmo gairdneri) at rest and after anesthesia and surgery.
General and comparative endocrinology.
1989 Mar; 73(3):390-7. doi:
10.1016/0016-6480(89)90196-2. [PMID: 2925078] - M Nieminen, M Laitinen, P Pasanen. Effects of anaesthesia with tricaine (MS 222) on the blood composition of the splake (Salvelinus fontinalis X Salvelinus namaycush).
Comparative biochemistry and physiology. C: Comparative pharmacology.
1982; 73(2):271-6. doi:
10.1016/0306-4492(82)90120-4. [PMID: 6129096] - K A Wayson, H Downes, R K Lynn, N Gerber. Studies on the comparative pharmacology and selective toxicity of tricaine methanesulfonate: metabolism as a basis of the selective toxicity in poikilotherms.
The Journal of pharmacology and experimental therapeutics.
1976 Sep; 198(3):695-708. doi:
NULL. [PMID: 185356]