Antihelmycin (BioDeep_00001868486)

Main id: BioDeep_00000014716

 

Chemicals and Drugs


代谢物信息卡片


(2S,3R,3aS,4S,4S,5R,6R,6R,7S,7aS)-4-[(1R,2S,3R,5S,6R)-3-amino-2,6-dihydroxy-5-(methylamino)cyclohexyl]oxy-6-[(1R)-1-amino-2-hydroxyethyl]-6-(hydroxymethyl)spiro[4,6,7,7a-tetrahydro-3aH-[1,3]dioxolo[4,5-c]pyran-2,2-oxane]-3,4,5,7-tetrol

化学式: C20H37N3O13 (527.2326272)
中文名称: 潮霉素B溶液
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CNC1CC(C(C(C1O)OC2C3C(C(C(O2)CO)O)OC4(O3)C(C(C(C(O4)C(CO)N)O)O)O)O)N
InChI: InChI=1S/C20H37N3O13/c1-23-7-2-5(21)9(26)15(10(7)27)33-19-17-16(11(28)8(4-25)32-19)35-20(36-17)18(31)13(30)12(29)14(34-20)6(22)3-24/h5-19,23-31H,2-4,21-22H2,1H3/t5-,6+,7+,8-,9+,10-,11+,12-,13+,14-,15-,16+,17+,18-,19+,20?/m1/s1

描述信息

D000890 - Anti-Infective Agents > D000977 - Antiparasitic Agents > D000871 - Anthelmintics
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents
Hygromycin B is an aminoglycoside antibiotic active against prokaryotic and eukaryotic cells.

同义名列表

4 个代谢物同义名

(2S,3R,3aS,4S,4S,5R,6R,6R,7S,7aS)-4-[(1R,2S,3R,5S,6R)-3-amino-2,6-dihydroxy-5-(methylamino)cyclohexyl]oxy-6-[(1R)-1-amino-2-hydroxyethyl]-6-(hydroxymethyl)spiro[4,6,7,7a-tetrahydro-3aH-[1,3]dioxolo[4,5-c]pyran-2,2-oxane]-3,4,5,7-tetrol; Antihelmycin; Hygromycin B; Hygrovetine



数据库引用编号

11 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • M Reza Roushan, Chuchi Chen, Parisa Ahmadi, Valerie C A Ward. Agrobacterium tumefaciens-Mediated Genetic Engineering of Green Microalgae, Chlorella vulgaris. Journal of visualized experiments : JoVE. 2023 Oct; ?(200):. doi: 10.3791/65382. [PMID: 37955374]
  • Feng Song, Ivan Birukou, Mark Bednarcik, Scott Young. A UPLC-based activity assay method for aminoglycoside phosphotransferase 4-Ia (APH4): A Selectable marker of plant transformation. Enzyme and microbial technology. 2023 Oct; 172(?):110344. doi: 10.1016/j.enzmictec.2023.110344. [PMID: 37918205]
  • Samantha M Turk, Christopher J Indovina, Jacob M Miller, Danielle L Overton, Avery M Runnebohm, Cade J Orchard, Mary E Tragesser-Tiña, Samantha K Gosser, Ellen M Doss, Kyle A Richards, Courtney Broshar Irelan, Mahmoud M Daraghmi, Connor G Bailey, Julia M Niekamp, Kieran P Claypool, Sarah M Engle, Bryce W Buchanan, Kelsey A Woodruff, James B Olesen, Philip J Smaldino, Eric M Rubenstein. Lipid biosynthesis perturbation impairs endoplasmic reticulum-associated degradation. The Journal of biological chemistry. 2023 08; 299(8):104939. doi: 10.1016/j.jbc.2023.104939. [PMID: 37331602]
  • Mohammad Hossein Mirzaee, Masoumeh Emadpour. Advances in the Transformation of Cyclamen persicum Mill. Through Direct Regeneration Based on an Optimized Kanamycin Selection Scheme. Molecular biotechnology. 2023 May; ?(?):. doi: 10.1007/s12033-023-00758-3. [PMID: 37133706]
  • Xiaoqian Ding, Tianjie Yuan, Weiwei Chen, Xiachang Wang, Yiwen Chu, Xiao Liu, Yang Hu, Lihong Hu. Hygromycin A derivatives isolated from Streptomyces sp. PC-22 in the rhizosphere soil of Pulsatilla chinensis. The Journal of antibiotics. 2022 03; 75(3):176-180. doi: 10.1038/s41429-022-00506-w. [PMID: 35064242]
  • Nadja Leimer, Xiaoqian Wu, Yu Imai, Madeleine Morrissette, Norman Pitt, Quentin Favre-Godal, Akira Iinishi, Samta Jain, Mariaelena Caboni, Inga V Leus, Vincent Bonifay, Samantha Niles, Rachel Bargabos, Meghan Ghiglieri, Rachel Corsetti, Megan Krumpoch, Gabriel Fox, Sangkeun Son, Dorota Klepacki, Yury S Polikanov, Cecily A Freliech, Julie E McCarthy, Diane G Edmondson, Steven J Norris, Anthony D'Onofrio, Linden T Hu, Helen I Zgurskaya, Kim Lewis. A selective antibiotic for Lyme disease. Cell. 2021 10; 184(21):5405-5418.e16. doi: 10.1016/j.cell.2021.09.011. [PMID: 34619078]
  • Marina R A Montoya, Gabriela A Massa, Mabel N Colabelli, Azucena Del Carmen Ridao. Efficient Agrobacterium tumefaciens-mediated transformation system of Diaporthe caulivora. Journal of microbiological methods. 2021 05; 184(?):106197. doi: 10.1016/j.mimet.2021.106197. [PMID: 33713724]
  • Olga Zimmermannova, Kristina Felcmanova, Lenka Sacka, Anne-Sophie Colinet, Pierre Morsomme, Hana Sychrova. K+-specific importers Trk1 and Trk2 play different roles in Ca2+ homeostasis and signalling in Saccharomyces cerevisiae cells. FEMS yeast research. 2021 04; 21(3):. doi: 10.1093/femsyr/foab015. [PMID: 33640956]
  • Raffaello Castoria, Cecilia Miccoli, Giuseppe Barone, Davide Palmieri, Filippo De Curtis, Giuseppe Lima, Joseph Heitman, Giuseppe Ianiri. Molecular Tools for the Yeast Papiliotrema terrestris LS28 and Identification of Yap1 as a Transcription Factor Involved in Biocontrol Activity. Applied and environmental microbiology. 2021 03; 87(7):. doi: 10.1128/aem.02910-20. [PMID: 33452020]
  • M Scindiya, P Malathi, K Kaverinathan, A Ramesh Sundar, R Viswanathan. Knock-down of glucose transporter and sucrose non-fermenting gene in the hemibiotrophic fungus Colletotrichum falcatum causing sugarcane red rot. Molecular biology reports. 2021 Mar; 48(3):2053-2061. doi: 10.1007/s11033-021-06140-3. [PMID: 33660095]
  • Gabriel L Lozano, Changhui Guan, Yanzhuan Cao, Bradley R Borlee, Nichole A Broderick, Eric V Stabb, Jo Handelsman. A Chemical Counterpunch: Chromobacterium violaceum ATCC 31532 Produces Violacein in Response to Translation-Inhibiting Antibiotics. mBio. 2020 05; 11(3):. doi: 10.1128/mbio.00948-20. [PMID: 32430474]
  • Dandan Li, Xiaoqing Wei, Taiguo Liu, Changzhong Liu, Wanquan Chen, Yuan Hu Xuan, Li Gao. Establishment of an Agrobacterium tumefaciens-mediated transformation system for Tilletia foetida. Journal of microbiological methods. 2020 02; 169(?):105810. doi: 10.1016/j.mimet.2019.105810. [PMID: 31857144]
  • Kun Zhang, Jingjing Su, Min Xu, Zhihui Zhou, Xiaoyang Zhu, Xin Ma, Jingjing Hou, Lubin Tan, Zuofeng Zhu, Hongwei Cai, Fengxia Liu, Hongying Sun, Ping Gu, Chen Li, Yuntao Liang, Wensheng Zhao, Chuanqing Sun, Yongcai Fu. A common wild rice-derived BOC1 allele reduces callus browning in indica rice transformation. Nature communications. 2020 01; 11(1):443. doi: 10.1038/s41467-019-14265-0. [PMID: 31974373]
  • Silvia Rodríguez-Pires, Eduardo Antonio Espeso, Nuria Baró-Montel, Rosario Torres, Paloma Melgarejo, Antonieta De Cal. Labeling of Monilinia fructicola with GFP and Its Validation for Studies on Host-Pathogen Interactions in Stone and Pome Fruit. Genes. 2019 12; 10(12):. doi: 10.3390/genes10121033. [PMID: 31835779]
  • Jiannong Lu, Yuzhen Shi, Weijin Li, Sen Chen, Yafei Wang, Xiaolin He, Xuegui Yin. RcPAL, a key gene in lignin biosynthesis in Ricinus communis L. BMC plant biology. 2019 May; 19(1):181. doi: 10.1186/s12870-019-1777-z. [PMID: 31060493]
  • Larissa A Balabanova, Yuri N Shkryl, Lubov V Slepchenko, Yulia A Yugay, Tatiana Y Gorpenchenko, Natalia N Kirichuk, Yulia V Khudyakova, Irina Yu Bakunina, Anna B Podvolotskaya, Victor P Bulgakov, Aleksandra V Seitkalieva, Oksana M Son, Liudmila A Tekutyeva. Development of host strains and vector system for an efficient genetic transformation of filamentous fungi. Plasmid. 2019 01; 101(?):1-9. doi: 10.1016/j.plasmid.2018.11.002. [PMID: 30465791]
  • Xueying Gu, Jiamin Zhao, Hongkai Wang, Fu-Cheng Lin, Qingyuan Guo, Neeraj Shrivastava, Rajesh Jeewon. ATMT transformation efficiencies with native promoters in Botryosphaeria kuwatsukai causing ring rot disease in pear. World journal of microbiology & biotechnology. 2018 Nov; 34(12):179. doi: 10.1007/s11274-018-2559-8. [PMID: 30456633]
  • Jaber Dehghani, Khosro Adibkia, Ali Movafeghi, Abolfazl Barzegari, Mohammad M Pourseif, Hadi Maleki Kakelar, Asal Golchin, Yadollah Omidi. Stable transformation of Spirulina (Arthrospira) platensis: a promising microalga for production of edible vaccines. Applied microbiology and biotechnology. 2018 Nov; 102(21):9267-9278. doi: 10.1007/s00253-018-9296-7. [PMID: 30159589]
  • Shouyun Lv, Xin Chen, Chunye Mou, Shenghong Dai, Yinbing Bian, Heng Kang. Agrobacterium-mediated transformation of the ascomycete mushroom Morchella importuna using polyubiquitin and glyceraldehyde-3-phosphate dehydrogenase promoter-based binary vectors. World journal of microbiology & biotechnology. 2018 Sep; 34(10):148. doi: 10.1007/s11274-018-2529-1. [PMID: 30218324]
  • Jianyu Liu, Chunyan Song, Qiaozhen Li, Zhen Xu, Dan Zhang, Meiyan Zhang, Qi Tan, Xiaodong Shang. A colonized millet grain method for Agrobacterium-mediated transformation of the button mushroom Agaricus bisporus. Journal of microbiological methods. 2018 09; 152(?):148-153. doi: 10.1016/j.mimet.2018.07.018. [PMID: 30071256]
  • Claudia D Norzagaray-Valenzuela, Lourdes J Germán-Báez, Marco A Valdez-Flores, Sergio Hernández-Verdugo, Luke M Shelton, Angel Valdez-Ortiz. Establishment of an efficient genetic transformation method in Dunaliella tertiolecta mediated by Agrobacterium tumefaciens. Journal of microbiological methods. 2018 07; 150(?):9-17. doi: 10.1016/j.mimet.2018.05.010. [PMID: 29777738]
  • Jiaying Sun, Ruidi Xu, Shuqin Xiao, Yuanyuan Lu, Qifeng Zhang, Chunsheng Xue. Agrobacterium tumefaciens-mediated transformation as an efficient tool for insertional mutagenesis of Kabatiella zeae. Journal of microbiological methods. 2018 06; 149(?):96-100. doi: 10.1016/j.mimet.2018.05.004. [PMID: 29730323]
  • Glaucia B Cabral, Vera T C Carneiro, Ana Cristina M M Gomes, Ana Luiza Lacerda, Adriana P Martinelli, Diva M A Dusi. Genetic transformation of Brachiaria brizantha cv. Marandu by biolistics. Anais da Academia Brasileira de Ciencias. 2018 Apr; 90(2):1789-1797. doi: 10.1590/0001-3765201820170842. [PMID: 29898118]
  • Tao Xuan Vu, Tho Tien Ngo, Linh Thi Dam Mai, Tri-Thuc Bui, Diep Hong Le, Ha Thi Viet Bui, Huy Quang Nguyen, Binh Xuan Ngo, Van-Tuan Tran. A highly efficient Agrobacterium tumefaciens-mediated transformation system for the postharvest pathogen Penicillium digitatum using DsRed and GFP to visualize citrus host colonization. Journal of microbiological methods. 2018 01; 144(?):134-144. doi: 10.1016/j.mimet.2017.11.019. [PMID: 29175534]
  • Yueping Zhang, Huaxiang Qu, Ping Zhao, Yongping Tang, Jingsong Zhou, Shaochun Luo, Yuling Yin, Guangyu Chen. Generation and Screening of T-DNA Insertion Mutants Mediated by Agrobacterium tumefaciens in the Garden Asparagus Stem Blight Pathogen Phomopsis asparagi. Current microbiology. 2017 Nov; 74(11):1270-1277. doi: 10.1007/s00284-017-1312-0. [PMID: 28730458]
  • Y S Nai, M R Lee, S Kim, S J Lee, J C Kim, Y T Yang, J S Kim. Relationship between expression level of hygromycin B-resistant gene and Agrobacterium tumefaciens-mediated transformation efficiency in Beauveria bassiana JEF-007. Journal of applied microbiology. 2017 Sep; 123(3):724-731. doi: 10.1111/jam.13529. [PMID: 28667709]
  • Kim Christopher Cohrs, Joachim Burbank, Julia Schumacher. A new transformant selection system for the gray mold fungus Botrytis cinerea based on the expression of fenhexamid-insensitive ERG27 variants. Fungal genetics and biology : FG & B. 2017 03; 100(?):42-51. doi: 10.1016/j.fgb.2017.02.001. [PMID: 28188884]
  • Yuanyuan Lu, Shuqin Xiao, Fen Wang, Jiaying Sun, Likun Zhao, Libin Yan, Chunsheng Xue. Agrobacterium tumefaciens-mediated transformation as an efficient tool for insertional mutagenesis of Cercospora zeae-maydis. Journal of microbiological methods. 2017 02; 133(?):8-13. doi: 10.1016/j.mimet.2016.12.010. [PMID: 27965011]
  • Mebeaselassie Andargie, Chao Yang, Jianxiong Li. Generation of β-glucuronidase reporter-tagged strain to monitor Ustilaginoidea virens infection in rice. Journal of microbiological methods. 2016 12; 131(?):148-155. doi: 10.1016/j.mimet.2016.10.014. [PMID: 27789314]
  • Jorge Morales, Sofia Kokkori, Diana Weidauer, Jarrod Chapman, Eugene Goltsman, Daniel Rokhsar, Arthur R Grossman, Eva C M Nowack. Development of a toolbox to dissect host-endosymbiont interactions and protein trafficking in the trypanosomatid Angomonas deanei. BMC evolutionary biology. 2016 11; 16(1):247. doi: 10.1186/s12862-016-0820-z. [PMID: 27835948]
  • Meenakshi Sharma, Shiwani Guleria, Saurabh Kulshrestha. Diacylglycerol acyl transferase: A pathogenicity related gene in Colletotrichum gloeosporioides. Journal of basic microbiology. 2016 Nov; 56(11):1308-1315. doi: 10.1002/jobm.201500663. [PMID: 27254647]
  • Liang Chen, Qun Wang, Hua Chen, Gengwu Sun, Huixiang Liu, Hongkai Wang. Agrobacterium tumefaciens-mediated transformation of Botryosphaeria dothidea. World journal of microbiology & biotechnology. 2016 Jul; 32(7):106. doi: 10.1007/s11274-016-2045-0. [PMID: 27263001]
  • J Bernardi-Wenzel, M C Quecine, J L Azevedo, J A Pamphile. Agrobacterium-mediated transformation of Fusarium proliferatum. Genetics and molecular research : GMR. 2016 Jun; 15(2):. doi: 10.4238/gmr.15027944. [PMID: 27323127]
  • Ting Li, Bo Liu, Chih Ying Chen, Bing Yang. TALEN-Mediated Homologous Recombination Produces Site-Directed DNA Base Change and Herbicide-Resistant Rice. Journal of genetics and genomics = Yi chuan xue bao. 2016 05; 43(5):297-305. doi: 10.1016/j.jgg.2016.03.005. [PMID: 27180265]
  • Hui-Min Oung, Ke-Chun Lin, Tsung-Meng Wu, Nulu Naga Prafulla Chandrika, Chwan-Yang Hong. Hygromycin B-induced cell death is partly mediated by reactive oxygen species in rice (Oryza sativa L.). Plant molecular biology. 2015 Dec; 89(6):577-88. doi: 10.1007/s11103-015-0380-4. [PMID: 26415870]
  • Jiajia Yu, Yafen Zhang, Haifeng Cui, Peng Hu, Xiaoping Yu, Zihong Ye. An efficient genetic manipulation protocol for Ustilago esculenta. FEMS microbiology letters. 2015 Jun; 362(12):fnv087. doi: 10.1093/femsle/fnv087. [PMID: 26038251]
  • David Vela-Corcía, Diego Romero, Juan Antonio Torés, Antonio De Vicente, Alejandro Pérez-García. Transient transformation of Podosphaera xanthii by electroporation of conidia. BMC microbiology. 2015 Feb; 15(?):20. doi: 10.1186/s12866-014-0338-8. [PMID: 25651833]
  • Marcy Main, Bronwyn Frame, Kan Wang. Rice, Japonica (Oryza sativa L.). Methods in molecular biology (Clifton, N.J.). 2015; 1223(?):169-80. doi: 10.1007/978-1-4939-1695-5_13. [PMID: 25300839]
  • Charles A Leslie, Sriema L Walawage, Sandra L Uratsu, Gale McGranahan, Abhaya M Dandekar. Walnut (Juglans). Methods in molecular biology (Clifton, N.J.). 2015; 1224(?):229-41. doi: 10.1007/978-1-4939-1658-0_19. [PMID: 25416262]
  • Yuji Ishida, Masako Tsunashima, Yukoh Hiei, Toshihiko Komari. Wheat (Triticum aestivum L.) transformation using immature embryos. Methods in molecular biology (Clifton, N.J.). 2015; 1223(?):189-98. doi: 10.1007/978-1-4939-1695-5_15. [PMID: 25300841]
  • Chunxiang Fu, Timothy Hernandez, Chuanen Zhou, Zeng-Yu Wang. Alfalfa (Medicago sativa L.). Methods in molecular biology (Clifton, N.J.). 2015; 1223(?):213-21. doi: 10.1007/978-1-4939-1695-5_17. [PMID: 25300843]
  • Wenzhi Jiang, Andrew J Brueggeman, Kempton M Horken, Thomas M Plucinak, Donald P Weeks. Successful transient expression of Cas9 and single guide RNA genes in Chlamydomonas reinhardtii. Eukaryotic cell. 2014 Nov; 13(11):1465-9. doi: 10.1128/ec.00213-14. [PMID: 25239977]
  • Yan-Jun Zhang, Jin-Jin Zhao, Ming Xie, De-Liang Peng. Agrobacterium tumefaciens-mediated transformation in the entomopathogenic fungus Lecanicillium lecanii and development of benzimidazole fungicide resistant strains. Journal of microbiological methods. 2014 Oct; 105(?):168-73. doi: 10.1016/j.mimet.2014.07.033. [PMID: 25107375]
  • Fan-Ying Meng, Li Liu, Feng-Hui Yang, Chun-You Li, Jun Liu, Ping Zhou. Reversible immortalization of human hepatocytes mediated by retroviral transfer and site-specific recombination. World journal of gastroenterology. 2014 Sep; 20(36):13119-26. doi: 10.3748/wjg.v20.i36.13119. [PMID: 25278705]
  • Cyril Masante, Farah El Najjar, Andres Chang, Angela Jones, Carole L Moncman, Rebecca Ellis Dutch. The human metapneumovirus small hydrophobic protein has properties consistent with those of a viroporin and can modulate viral fusogenic activity. Journal of virology. 2014 Jun; 88(11):6423-33. doi: 10.1128/jvi.02848-13. [PMID: 24672047]
  • Andrew R G Plackett, Liandong Huang, Heather L Sanders, Jane A Langdale. High-efficiency stable transformation of the model fern species Ceratopteris richardii via microparticle bombardment. Plant physiology. 2014 May; 165(1):3-14. doi: 10.1104/pp.113.231357. [PMID: 24623851]
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  • Ru Tao, You-Can Zhang, Qian Fang, Ren-Jiu Shi, Yan-Ling Li, Lu-Qi Huang, Gang-Ping Hao. [Construction of plant expression vectors with PMI gene as selection marker and their utilization in transformation of Salvia miltiorrhiza f. alba]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2014 Apr; 39(7):1209-13. doi: . [PMID: 25011255]
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  • Hui-Chen Guo, Shi-Qi Sun, De-Hui Sun, Yan-Quan Wei, Jin Xu, Mei Huang, Xiang-Tao Liu, Zai-Xin Liu, Jian-Xiong Luo, Hong Yin, Ding Xiang Liu. Viroporin activity and membrane topology of classic swine fever virus p7 protein. The international journal of biochemistry & cell biology. 2013 Jul; 45(7):1186-94. doi: 10.1016/j.biocel.2013.03.021. [PMID: 23583663]
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  • Caixia Wang, Xiangnan Guan, Hanyan Wang, Guifang Li, Xiangli Dong, Guoping Wang, Baohua Li. Agrobacterium tumefaciens-mediated transformation of Valsa mali: an efficient tool for random insertion mutagenesis. TheScientificWorldJournal. 2013; 2013(?):968432. doi: 10.1155/2013/968432. [PMID: 24381526]
  • Xiang Liu, Chun-Miao Feng, Robert Franks, Rongda Qu, De-Yu Xie, Qiu-Yun Jenny Xiang. Plant regeneration and genetic transformation of C. canadensis: a non-model plant appropriate for investigation of flower development in Cornus (Cornaceae). Plant cell reports. 2013 Jan; 32(1):77-87. doi: 10.1007/s00299-012-1341-x. [PMID: 23111786]
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  • Chun-Yu Zhang, Hong-Yu Li, Bin Liu. [A comparison study of hpt and bar as selection marker gene of transgenic rice]. Yi chuan = Hereditas. 2012 Dec; 34(12):1599-606. doi: 10.3724/sp.j.1005.2012.01599. [PMID: 23262108]
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