OXYCHLORDANE (BioDeep_00001868353)

Main id: BioDeep_00000012112

 

Volatile Flavor Compounds


代谢物信息卡片


(1S,8R)-1,5,6,8,9,10,11,11-octachloro-4-oxatetracyclo[6.2.1.02,7.03,5]undec-9-ene

化学式: C10H4Cl8O (419.77703740000004)
中文名称: 氧化氯丹
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C12C(C(C3(C1O3)Cl)Cl)C4(C(=C(C2(C4(Cl)Cl)Cl)Cl)Cl)Cl
InChI: InChI=1S/C10H4Cl8O/c11-3-1-2(6-9(3,16)19-6)8(15)5(13)4(12)7(1,14)10(8,17)18/h1-3,6H/t1?,2?,3?,6?,7-,8+,9?/m1/s1

描述信息

同义名列表

3 个代谢物同义名

(1S,8R)-1,5,6,8,9,10,11,11-octachloro-4-oxatetracyclo[6.2.1.02,7.03,5]undec-9-ene; OXYCHLORDANE; Oxychlordane



数据库引用编号

7 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Jan Ove Bustnes, Bård-Jørgen Bårdsen, Børge Moe, Dorte Herzke, Manuel Ballesteros, Anette Fenstad, Katrine Borgå, Ingjerd S Krogseth, Igor Eulaers, Lovise P Skogeng, Geir W Gabrielsen, Sveinn-Are Hanssen. Impacts of a warming climate on concentrations of organochlorines in a fasting high arctic marine bird: Direct vs. indirect effects?. The Science of the total environment. 2023 Oct; 908(?):168096. doi: 10.1016/j.scitotenv.2023.168096. [PMID: 37914131]
  • Lawrence S Engel, Emily C Zabor, Jaya Satagopan, Anders Widell, Nathaniel Rothman, Thomas R O'Brien, Mingdong Zhang, Stephen K Van Den Eeden, Tom K Grimsrud. Prediagnostic serum organochlorine insecticide concentrations and primary liver cancer: A case-control study nested within two prospective cohorts. International journal of cancer. 2019 11; 145(9):2360-2371. doi: 10.1002/ijc.32175. [PMID: 30701531]
  • Edward C Meek, Dana Dale Jones, J Allen Crow, Robert W Wills, William H Cooke, Janice E Chambers. Association of serum levels of p,p'- Dichlorodiphenyldichloroethylene (DDE) with type 2 diabetes in African American and Caucasian adult men from agricultural (Delta) and non-agricultural (non-Delta) regions of Mississippi. Journal of toxicology and environmental health. Part A. 2019; 82(6):387-400. doi: 10.1080/15287394.2019.1610678. [PMID: 31064277]
  • Leah Weber, Kevin Song, Terry Boyle, Éric Gaudreau, Agnes Lai, Heather J Sutherland, Alain LeBlanc, John J Spinelli. Organochlorine Levels in Plasma and Risk of Multiple Myeloma. Journal of occupational and environmental medicine. 2018 10; 60(10):911-916. doi: 10.1097/jom.0000000000001387. [PMID: 30289833]
  • George Eli Howell, Erin McDevitt, Lucie Henein, Charlee Mulligan, Darian Young. Alterations in cellular lipid metabolism produce neutral lipid accumulation following exposure to the organochlorine compound trans-nonachlor in rat primary hepatocytes. Environmental toxicology. 2018 Sep; 33(9):962-971. doi: 10.1002/tox.22583. [PMID: 29964320]
  • B González-Alzaga, M Lacasaña, A F Hernández, J P Arrebola, I López-Flores, F Artacho-Cordón, J P Bonde, N Olea, C Aguilar-Garduño. Serum concentrations of organochlorine compounds and predictors of exposure in children living in agricultural communities from South-Eastern Spain. Environmental pollution (Barking, Essex : 1987). 2018 Jun; 237(?):685-694. doi: 10.1016/j.envpol.2017.10.109. [PMID: 29129429]
  • Mohamed Abou-Elwafa Abdallah, Amen Hamdy Zaky, Adrian Covaci. Levels and profiles of organohalogenated contaminants in human blood from Egypt. Chemosphere. 2017 Jun; 176(?):266-272. doi: 10.1016/j.chemosphere.2017.02.139. [PMID: 28273534]
  • Anne-Mary Lewis-Mikhael, Rocío Olmedo-Requena, Virginia Martínez-Ruiz, Aurora Bueno-Cavanillas, José Juan Jiménez-Moleón. Organochlorine pesticides and prostate cancer, Is there an association? A meta-analysis of epidemiological evidence. Cancer causes & control : CCC. 2015 Oct; 26(10):1375-92. doi: 10.1007/s10552-015-0643-z. [PMID: 26245248]
  • Sunmi Kim, Jeongim Park, Hai-Joong Kim, Jeong Jae Lee, Gyuyeon Choi, Sooran Choi, Sungjoo Kim, Su Young Kim, Duk Hee Lee, Hyo-Bang Moon, Sungkyoon Kim, Kyungho Choi. Association between Several Persistent Organic Pollutants in Serum and Adipokine Levels in Breast Milk among Lactating Women of Korea. Environmental science & technology. 2015 Jul; 49(13):8033-40. doi: 10.1021/acs.est.5b00520. [PMID: 26054256]
  • Se-A Kim, Yu-Mi Lee, Ho-Won Lee, David R Jacobs, Duk-Hee Lee. Greater cognitive decline with aging among elders with high serum concentrations of organochlorine pesticides. PloS one. 2015; 10(6):e0130623. doi: 10.1371/journal.pone.0130623. [PMID: 26107947]
  • Michio X Watanabe, Tatsuya Kunisue, Norifumi Ueda, Masato Nose, Shinsuke Tanabe, Hisato Iwata. Toxicokinetics of dioxins and other organochlorine compounds in Japanese people: association with hepatic CYP1A2 expression levels. Environment international. 2013 Mar; 53(?):53-61. doi: 10.1016/j.envint.2012.12.008. [PMID: 23333656]
  • Warren G Foster, Anthony P Cheung, Karelyn Davis, Gillian Graves, John Jarrell, Alain Leblanc, Chun Lei Liang, Tara Leech, Mark Walker, Jean Philippe Weber, Jay Van Oostdam. Circulating metals and persistent organic pollutant concentrations in Canadian and non-Canadian born primiparous women from five Canadian centres: results of a pilot biomonitoring study. The Science of the total environment. 2012 Oct; 435-436(?):326-36. doi: 10.1016/j.scitotenv.2012.06.070. [PMID: 22863808]
  • Britton Trabert, Matthew P Longnecker, John W Brock, Mark A Klebanoff, Katherine A McGlynn. Maternal pregnancy levels of trans-nonachlor and oxychlordane and prevalence of cryptorchidism and hypospadias in boys. Environmental health perspectives. 2012 Mar; 120(3):478-82. doi: 10.1289/ehp.1103936. [PMID: 21975279]
  • Veerle L B Jaspers, Rune Dietz, Christian Sonne, Robert J Letcher, Marcel Eens, Hugo Neels, Erik W Born, Adrian Covaci. A screening of persistent organohalogenated contaminants in hair of East Greenland polar bears. The Science of the total environment. 2010 Oct; 408(22):5613-8. doi: 10.1016/j.scitotenv.2010.07.059. [PMID: 20800875]
  • Duk-Hee Lee, Michael W Steffes, Andreas Sjödin, Richard S Jones, Larry L Needham, David R Jacobs. Low dose of some persistent organic pollutants predicts type 2 diabetes: a nested case-control study. Environmental health perspectives. 2010 Sep; 118(9):1235-42. doi: 10.1289/ehp.0901480. [PMID: 20444671]
  • Mark P Purdue, Lawrence S Engel, Hilde Langseth, Larry L Needham, Aage Andersen, Dana B Barr, Aaron Blair, Nathaniel Rothman, Katherine A McGlynn. Prediagnostic serum concentrations of organochlorine compounds and risk of testicular germ cell tumors. Environmental health perspectives. 2009 Oct; 117(10):1514-9. doi: 10.1289/ehp.0800359. [PMID: 20019899]
  • Heli Routti, Bert van Bavel, Robert J Letcher, Augustine Arukwe, Shaogang Chu, Geir W Gabrielsen. Concentrations, patterns and metabolites of organochlorine pesticides in relation to xenobiotic phase I and II enzyme activities in ringed seals (Phoca hispida) from Svalbard and the Baltic Sea. Environmental pollution (Barking, Essex : 1987). 2009 Aug; 157(8-9):2428-34. doi: 10.1016/j.envpol.2009.03.008. [PMID: 19329238]
  • John J Spinelli, Carmen H Ng, Jean-Philippe Weber, Joseph M Connors, Randy D Gascoyne, Agnes S Lai, Angela R Brooks-Wilson, Nhu D Le, Brian R Berry, Richard P Gallagher. Organochlorines and risk of non-Hodgkin lymphoma. International journal of cancer. 2007 Dec; 121(12):2767-75. doi: 10.1002/ijc.23005. [PMID: 17722095]
  • Tatsuya Kunisue, Nozomi Takayanagi, Toshio Tsubota, Shinsuke Tanabe. Persistent organochlorines in raccoon dogs (Nyctereutes procyonoides) from Japan: Hepatic sequestration of oxychlordane. Chemosphere. 2007 Jan; 66(2):203-11. doi: 10.1016/j.chemosphere.2006.06.001. [PMID: 16839592]
  • Duk-Hee Lee, In-Kyu Lee, Kyungeun Song, Michael Steffes, William Toscano, Beth A Baker, David R Jacobs. A strong dose-response relation between serum concentrations of persistent organic pollutants and diabetes: results from the National Health and Examination Survey 1999-2002. Diabetes care. 2006 Jul; 29(7):1638-44. doi: 10.2337/dc06-0543. [PMID: 16801591]
  • Judy Akkina, John Reif, Thomas Keefe, Annette Bachand. Age at natural menopause and exposure to organochlorine pesticides in Hispanic women. Journal of toxicology and environmental health. Part A. 2004 Sep; 67(18):1407-22. doi: 10.1080/15287390490483845. [PMID: 15371229]
  • Richard A Cassidy, George M Vaughan, Basil A Pruitt, Arthur D Mason. Xenoestrogens: do they lower survival after thermal injury?. Archives of environmental health. 2003 Sep; 58(9):597-604. doi: NULL. [PMID: 15369279]
  • Wim J M Hegeman, Remi W P M Laane. Enantiomeric enrichment of chiral pesticides in the environment. Reviews of environmental contamination and toxicology. 2002; 173(?):85-116. doi: NULL. [PMID: 11776751]
  • T Zheng, T R Holford, J Tessari, S T Mayne, S H Zahm, P H Owens, B Zhang, B Ward, D Carter, Y Zhang, W Zhang, R Dubrow, P Boyle. Oxychlordane and trans-nonachlor in breast adipose tissue and risk of female breast cancer. Journal of epidemiology and biostatistics. 2000; 5(3):153-60. doi: . [PMID: 11051111]
  • H Mussalo-Rauhamaa, H Pyysalo, K Antervo. Heptachlor, heptachlor epoxide, and other chlordane compounds in Finnish plywood workers. Archives of environmental health. 1991 Nov; 46(6):340-6. doi: 10.1080/00039896.1991.9934400. [PMID: 1772258]
  • K Takamiya. Residual levels of plasma oxychlordane and trans-nonachlor in pest control operators and some characteristics of these accumulations. Bulletin of environmental contamination and toxicology. 1987 Nov; 39(5):750-5. doi: 10.1007/bf01855850. [PMID: 3690000]
  • K W Johnson, N E Kaminski, A E Munson. Direct suppression of cultured spleen cell responses by chlordane and the basis for differential effects on in vivo and in vitro immunocompetence. Journal of toxicology and environmental health. 1987; 22(4):497-515. doi: 10.1080/15287398709531089. [PMID: 3694709]
  • R Murphy, C Harvey. Residues and metabolites of selected persistent halogenated hydrocarbons in blood specimens from a general population survey. Environmental health perspectives. 1985 May; 60(?):115-20. doi: 10.1289/ehp.8560115. [PMID: 2411534]