2,3,3,4,4,5-PCB (BioDeep_00001868331)

Main id: BioDeep_00000012094

 

Industrial Pollutants Volatile Flavor Compounds


代谢物信息卡片


2,3,3,4,4,5-HEXACHLOROBIPHENYL

化学式: C12H4Cl6 (357.8444164)
中文名称: 2,3,3,4,4,5-六氯联苯
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1=CC(=C(C=C1C2=CC(=C(C(=C2Cl)Cl)Cl)Cl)Cl)Cl
InChI: InChI=1S/C12H4Cl6/c13-7-2-1-5(3-8(7)14)6-4-9(15)11(17)12(18)10(6)16/h1-4H

描述信息

D004785 - Environmental Pollutants > D011078 - Polychlorinated Biphenyls

同义名列表

3 个代谢物同义名

2,3,3,4,4,5-HEXACHLOROBIPHENYL; 2,3,3,4,4,5-PCB; 2,3,3',4,4',5-Hexachlorobiphenyl



数据库引用编号

8 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • A Vieira Silva, I Chu, M Feeley, Å Bergman, H Håkansson, M Öberg. Dose-dependent toxicological effects in rats following a 90-day dietary exposure to PCB-156 include retinoid disruption. Reproductive toxicology (Elmsford, N.Y.). 2022 01; 107(?):123-139. doi: 10.1016/j.reprotox.2021.09.012. [PMID: 34560258]
  • Yuan Tian, Wei Gui, Bipin Rimal, Imhoi Koo, Philip B Smith, Robert G Nichols, Jingwei Cai, Qing Liu, Andrew D Patterson. Metabolic impact of persistent organic pollutants on gut microbiota. Gut microbes. 2020 11; 12(1):1-16. doi: 10.1080/19490976.2020.1848209. [PMID: 33295235]
  • Qiuli Shan, Ningning Chen, Wei Liu, Fan Qu, Anhui Chen. Exposure to 2,3,3',4,4',5-hexachlorobiphenyl promotes nonalcoholic fatty liver disease development in C57BL/6 mice. Environmental pollution (Barking, Essex : 1987). 2020 Aug; 263(Pt A):114563. doi: 10.1016/j.envpol.2020.114563. [PMID: 32304952]
  • Ningning Chen, Qiuli Shan, Yu Qi, Wei Liu, Xiaojun Tan, Jinsong Gu. Transcriptome analysis in normal human liver cells exposed to 2, 3, 3', 4, 4', 5 - Hexachlorobiphenyl (PCB 156). Chemosphere. 2020 Jan; 239(?):124747. doi: 10.1016/j.chemosphere.2019.124747. [PMID: 31514003]
  • Ho Jung Moon, Jung-Eun Lim, Sun Ha Jee. Association between serum concentrations of persistent organic pollutants and smoking in Koreans: A cross-sectional study. Journal of epidemiology. 2017 Feb; 27(2):63-68. doi: 10.1016/j.je.2016.09.006. [PMID: 28142013]
  • Hermann Fromme, Michael Albrecht, Markus Appel, Bettina Hilger, Wolfgang Völkel, Bernhard Liebl, Eike Roscher. PCBs, PCDD/Fs, and PBDEs in blood samples of a rural population in South Germany. International journal of hygiene and environmental health. 2015 Jan; 218(1):41-6. doi: 10.1016/j.ijheh.2014.07.004. [PMID: 25127490]
  • Karin I van Ede, Patrik L Andersson, Konrad P J Gaisch, Martin van den Berg, Majorie B M van Duursen. Comparison of intake and systemic relative effect potencies of dioxin-like compounds in female rats after a single oral dose. Archives of toxicology. 2014 Mar; 88(3):637-46. doi: 10.1007/s00204-013-1186-2. [PMID: 24363026]
  • Susanne Hansen, Marin Strøm, Sjurdur F Olsen, Ekaterina Maslova, Panu Rantakokko, Hannu Kiviranta, Dorte Rytter, Bodil H Bech, Linda V Hansen, Thorhallur I Halldorsson. Maternal concentrations of persistent organochlorine pollutants and the risk of asthma in offspring: results from a prospective cohort with 20 years of follow-up. Environmental health perspectives. 2014 Jan; 122(1):93-9. doi: 10.1289/ehp.1206397. [PMID: 24162035]
  • Karin I van Ede, Patrik L Andersson, Konrad P J Gaisch, Martin van den Berg, Majorie B M van Duursen. Comparison of intake and systemic relative effect potencies of dioxin-like compounds in female mice after a single oral dose. Environmental health perspectives. 2013 Jul; 121(7):847-53. doi: 10.1289/ehp.1206336. [PMID: 23674508]
  • Matt Cave, Savitri Appana, Mihir Patel, Keith Cameron Falkner, Craig J McClain, Guy Brock. Polychlorinated biphenyls, lead, and mercury are associated with liver disease in American adults: NHANES 2003-2004. Environmental health perspectives. 2010 Dec; 118(12):1735-42. doi: 10.1289/ehp.1002720. [PMID: 21126940]
  • Michio X Watanabe, Hisato Iwata, Mio Okamoto, Eun-Young Kim, Kumiko Yoneda, Takuma Hashimoto, Shinsuke Tanabe. Induction of cytochrome P450 1A5 mRNA, protein and enzymatic activities by dioxin-like compounds, and congener-specific metabolism and sequestration in the liver of wild jungle crow (Corvus macrorhynchos) from Tokyo, Japan. Toxicological sciences : an official journal of the Society of Toxicology. 2005 Dec; 88(2):384-99. doi: 10.1093/toxsci/kfi326. [PMID: 16177242]
  • M Haag-Grönlund, Y Kato, R Fransson-Steen, G Scheu, L Wärngârd. Promotion of enzyme altered foci in female rat 2,3,3',4,4',5-hexachlorobiphenyl. Toxicology and applied pharmacology. 1997 Nov; 147(1):46-55. doi: 10.1006/taap.1997.8258. [PMID: 9356306]
  • A P Van Birgelen, E A Smit, I M Kampen, C N Groeneveld, K M Fase, J Van der Kolk, H Poiger, M Van den Berg, J H Koeman, A Brouwer. Subchronic effects of 2,3,7,8-TCDD or PCBs on thyroid hormone metabolism: use in risk assessment. European journal of pharmacology. 1995 May; 293(1):77-85. doi: 10.1016/0926-6917(95)90021-7. [PMID: 7672011]
  • A P Van Birgelen, J Van der Kolk, K M Fase, I Bol, H Poiger, M Van den Berg, A Brouwer. Toxic potency of 2,3,3',4,4',5-hexachlorobiphenyl relative to and in combination with 2,3,7,8-tetrachlorodibenzo-p-dioxin in a subchronic feeding study in the rat. Toxicology and applied pharmacology. 1994 Jun; 126(2):202-13. doi: 10.1006/taap.1994.1109. [PMID: 8209374]