Triamcinolone diacetate (BioDeep_00001868291)
Main id: BioDeep_00000006680
代谢物信息卡片
化学式: C25H31FO8 (478.20028579999996)
中文名称: 曲安西龙双醋酸酯, 醋酸曲安西龙双
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC(=O)OCC(=O)C1(C(CC2C1(CC(C3(C2CCC4=CC(=O)C=CC43C)F)O)C)OC(=O)C)O
InChI: InChI=1S/C25H31FO8/c1-13(27)33-12-20(31)25(32)21(34-14(2)28)10-18-17-6-5-15-9-16(29)7-8-22(15,3)24(17,26)19(30)11-23(18,25)4/h7-9,17-19,21,30,32H,5-6,10-12H2,1-4H3/t17-,18-,19-,21+,22-,23-,24-,25+/m0/s1
描述信息
C147908 - Hormone Therapy Agent > C548 - Therapeutic Hormone > C1636 - Therapeutic Steroid Hormone
C308 - Immunotherapeutic Agent > C574 - Immunosuppressant > C211 - Therapeutic Corticosteroid
D004791 - Enzyme Inhibitors
同义名列表
1 个代谢物同义名
数据库引用编号
8 个数据库交叉引用编号
- ChEBI: CHEBI:9669
- KEGG: C08184
- KEGGdrug: D00984
- PubChem: 6216
- ChEMBL: CHEMBL1200449
- CAS: 67-78-7
- PubChem: 10384
- NIKKAJI: J4.852F
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome.
Cell reports.
2021 04; 35(4):109040. doi:
10.1016/j.celrep.2021.109040. [PMID: 33910017] - Tobie D Lee, Olivia W Lee, Kyle R Brimacombe, Lu Chen, Rajarshi Guha, Sabrina Lusvarghi, Bethilehem G Tebase, Carleen Klumpp-Thomas, Robert W Robey, Suresh V Ambudkar, Min Shen, Michael M Gottesman, Matthew D Hall. A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein.
Molecular pharmacology.
2019 11; 96(5):629-640. doi:
10.1124/mol.119.115964. [PMID: 31515284] - Diane Felsen, David Schulsinger, Steven S Gross, Francis Y Kim, Donald Marion, E Darracott Vaughan. Renal hemodynamic and ureteral pressure changes in response to ureteral obstruction: the role of nitric oxide.
The Journal of urology.
2003 Jan; 169(1):373-6. doi:
10.1097/01.ju.0000039820.60560.74. [PMID: 12478193] - T Yamamoto, I Katayama, K Nishioka. Increased plasma interleukin-6 in cutaneous plasmacytoma: the effect of intralesional steroid therapy.
The British journal of dermatology.
1997 Oct; 137(4):631-6. doi:
10.1111/j.1365-2133.1997.tb03801.x. [PMID: 9390345] - K A Moriello, S L Fehrer-Sawyer, D J Meyer, B Feder. Adrenocortical suppression associated with topical otic administration of glucocorticoids in dogs.
Journal of the American Veterinary Medical Association.
1988 Aug; 193(3):329-31. doi:
NULL. [PMID: 2846483] - M Kurowski. [Pharmacokinetics and biological availability of diclofenac preparations following intramuscular injection of 75 mg and oral administration of 150 mg of active drug].
Zeitschrift fur Rheumatologie.
1988 Jan; 47(1):37-42. doi:
NULL. [PMID: 3369245] - T Mitamura. Glucocorticoid-induced elevation of serum high-density lipoprotein-cholesterol and its reversal by adrenocorticotropin in the rat.
Biochimica et biophysica acta.
1987 Jan; 917(1):121-30. doi:
10.1016/0005-2760(87)90292-x. [PMID: 3024735] - R Gniazdowski. [Incorrect treatment of patients with allergic disorders].
Wiadomosci lekarskie (Warsaw, Poland : 1960).
1986 Feb; 39(4):275-82. doi:
". [PMID: 3088844] - H Derendorf, G Mullersman, J Barth, A Grüner, H Möllmann. Pharmacokinetics of diclofenac sodium after intramuscular administration in combination with triamcinolone acetate.
European journal of clinical pharmacology.
1986; 31(3):363-5. doi:
10.1007/bf00981139. [PMID: 3792436] - R E Moore, J B Hansen, H A Lardy, C M Veneziale. The development and application of a radioimmunoassay for rat phosphoenolpyruvate carboxykinase.
The Journal of biological chemistry.
1982 Nov; 257(21):12546-52. doi:
10.1016/s0021-9258(18)33545-2. [PMID: 7130165] - L V Egorova, L P Papaian, P V Khrolova, S D Volkova, Z D Fedorova. [Hormone therapy of renal hemorrhages in hemophiliacs].
Sovetskaia meditsina.
1982; ?(8):25-8. doi:
NULL. [PMID: 7147040] - J Zaumseil, L Kersten, H Bräunlich. [Age related effects of furosemide in the rat].
Archives internationales de pharmacodynamie et de therapie.
1975 Nov; 218(1):167-76. doi:
NULL. [PMID: 2118] - J RIVADENEYRA. [INVESTIGATION OF THE BIOLOGICAL ACTIVITIES OF TRIAMCINOLONE DIACETATE IN PATIENTS WITH ADRENAL INSUFFICIENCY].
Revista medica del Hospital General.
1964 Mar; 27(?):161-71. doi:
NULL. [PMID: 14153049]