Piperonyl sulfoxide (BioDeep_00001868167)
Main id: BioDeep_00000012643
代谢物信息卡片
1,3-Benzodioxole,5-[2-(octylsulfinyl)propyl]-
化学式: C18H28O3S (324.1759)
中文名称: 亚砜
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CCCCCCCCS(=O)C(C)CC1=CC2=C(C=C1)OCO2
InChI: InChI=1S/C18H28O3S/c1-3-4-5-6-7-8-11-22(19)15(2)12-16-9-10-17-18(13-16)21-14-20-17/h9-10,13,15H,3-8,11-12,14H2,1-2H3
描述信息
D010575 - Pesticides > D007306 - Insecticides
D016573 - Agrochemicals
同义名列表
数据库引用编号
8 个数据库交叉引用编号
- ChEBI: CHEBI:82267
- KEGG: C19147
- PubChem: 8442
- ChEMBL: CHEMBL3184866
- CAS: 120-62-7
- PubChem: 124489819
- KNApSAcK: C00049313
- KNApSAcK: 82267
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
- 56018 - Petasites: 10.1016/S0031-9422(97)00581-5
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
| 亚细胞结构定位 | 关联基因列表 |
|---|
文献列表
- Fu-Mao Zhang, Ting Huang, Feng Wang, Gui-Shan Zhang, Donglan Liu, Jun Dai, Jian-Wei Zhang, Qing-Hua Li, Guo-Qiang Lin, Dingding Gao, Jincun Zhao, Ping Tian. Discovery of highly potent covalent SARS-CoV-2 3CLpro inhibitors bearing 2-sulfoxyl-1,3,4-oxadiazole scaffold for combating COVID-19.
European journal of medicinal chemistry.
2023 Aug; 260(?):115721. doi:
10.1016/j.ejmech.2023.115721. [PMID: 37598484] - Claudia Sanfilippo, Federica Cernuto, Angela Patti. Expanding the Use of Peroxygenase from Oat Flour in Organic Synthesis: Enantioselective Oxidation of Sulfides.
International journal of molecular sciences.
2023 Apr; 24(8):. doi:
10.3390/ijms24087464. [PMID: 37108626] - Katharina Friedrich, Nicole S Wermter, Lars Andernach, Katja Witzel, Franziska S Hanschen. Formation of volatile sulfur compounds and S-methyl-l-cysteine sulfoxide in Brassica oleracea vegetables.
Food chemistry.
2022 Jul; 383(?):132544. doi:
10.1016/j.foodchem.2022.132544. [PMID: 35247727] - Xiangqian Ye, Xiaoling Zou, Fafu Tian, Honglin He. Feasibility study on recycled vegetable oil waste and recycled polyethylene for the modification of aged asphalt.
PloS one.
2021; 16(1):e0244159. doi:
10.1371/journal.pone.0244159. [PMID: 33400695] - Li-Jun Yue, Xi-Yu Zhu, Rui-Sha Li, Hui-Jing Chang, Bing Gong, Chong-Chong Tian, Chang Liu, Yun-Xing Xue, Qing Zhou, Tian-Shu Xu, Dong-Jin Wang. S‑allyl‑cysteine sulfoxide (alliin) alleviates myocardial infarction by modulating cardiomyocyte necroptosis and autophagy.
International journal of molecular medicine.
2019 Nov; 44(5):1943-1951. doi:
10.3892/ijmm.2019.4351. [PMID: 31573046] - Kamlesh S Yadav, Pratibha Yadav, Satyawati Sharma, Sunil K Khare. Role of Musa paradisiaca ascorbate peroxidase in the transformation of methyl phenyl sulfide to its sulfoxide.
International journal of biological macromolecules.
2019 Feb; 122(?):962-968. doi:
10.1016/j.ijbiomac.2018.11.014. [PMID: 30408454] - A L Wollenberg, T M O'Shea, J H Kim, A Czechanski, L G Reinholdt, M V Sofroniew, T J Deming. Injectable polypeptide hydrogels via methionine modification for neural stem cell delivery.
Biomaterials.
2018 09; 178(?):527-545. doi:
10.1016/j.biomaterials.2018.03.057. [PMID: 29657091] - Chun-Shun Li, Ariel M Sarotti, Peng Huang, Uyen T Dang, Julian G Hurdle, Tamara P Kondratyuk, John M Pezzuto, James Turkson, Shugeng Cao. NF-κB inhibitors, unique γ-pyranol-γ-lactams with sulfide and sulfoxide moieties from Hawaiian plant Lycopodiella cernua derived fungus Paraphaeosphaeria neglecta FT462.
Scientific reports.
2017 09; 7(1):10424. doi:
10.1038/s41598-017-10537-1. [PMID: 28874704] - Katsunori Anezaki, Ayaka Matsuda, Takashi Matsuishi. Concentration and congener pattern of polychlorinated biphenyls in blubber and liver of Hubbs' beaked whale (Mesoplodon carlhubbsi), using a sulfoxide and an Ag-ION solid phase extraction cartridge as a simplified cleanup technique for biological samples.
Marine pollution bulletin.
2016 Dec; 113(1-2):282-286. doi:
10.1016/j.marpolbul.2016.09.051. [PMID: 27707471] - Ewelina Krol, Gabriela Pastuch-Gawolek, Dawid Nidzworski, Michal Rychlowski, Wieslaw Szeja, Grzegorz Grynkiewicz, Boguslaw Szewczyk. Synthesis and antiviral activity of a novel glycosyl sulfoxide against classical swine fever virus.
Bioorganic & medicinal chemistry.
2014 May; 22(9):2662-70. doi:
10.1016/j.bmc.2014.03.027. [PMID: 24721828] - Ramon Lavado, Rosaura Aparicio-Fabre, Daniel Schlenk. Effects of salinity acclimation on the pesticide-metabolizing enzyme flavin-containing monooxygenase (FMO) in rainbow trout (Oncorhynchus mykiss).
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP.
2013 Jan; 157(1):9-15. doi:
10.1016/j.cbpc.2012.08.004. [PMID: 22981832] - Mario Thevis, Ines Möller, Simon Beuck, Wilhelm Schänzer. Synthesis, mass spectrometric characterization, and analysis of the PPARδ agonist GW1516 and its major human metabolites: targets in sports drug testing.
Methods in molecular biology (Clifton, N.J.).
2013; 952(?):301-12. doi:
10.1007/978-1-62703-155-4_22. [PMID: 23100242] - Danielle S Fisher, Simon A Handley, Robert J Flanagan, David M Taylor. Plasma concentrations of quetiapine, N-desalkylquetiapine, o-desalkylquetiapine, 7-hydroxyquetiapine, and quetiapine sulfoxide in relation to quetiapine dose, formulation, and other factors.
Therapeutic drug monitoring.
2012 Aug; 34(4):415-21. doi:
10.1097/ftd.0b013e3182603f62. [PMID: 22777152] - Abhijeet Y Deshpande, Sandip Gurav, Ravindra Punde, Vishal Zambre, Rahul Kulkarni, Sarvesh Pandey, Ashish Mungantiwar, Ramesh Mullangi. Development and validation of a highly sensitive LC-MS/MS method for simultaneous quantitation of ethionamide and ethionamide sulfoxide in human plasma: application to a human pharmacokinetic study.
Biomedical chromatography : BMC.
2011 Sep; 25(9):985-94. doi:
10.1002/bmc.1554. [PMID: 21268048] - Masayuki Inoue, Naoki Shinohara, Shintaro Tanabe, Tomoaki Takahashi, Ken Okura, Hiroaki Itoh, Yuki Mizoguchi, Maiko Iida, Nayoung Lee, Shigeru Matsuoka. Total synthesis of the large non-ribosomal peptide polytheonamide B.
Nature chemistry.
2010 Apr; 2(4):280-5. doi:
10.1038/nchem.554. [PMID: 21124508] - T Galeano Díaz, A Guiberteau Cabanillas, M D López Soto, J M Ortiz. Determination of fenthion and fenthion-sulfoxide, in olive oil and in river water, by square-wave adsorptive-stripping voltammetry.
Talanta.
2008 Aug; 76(4):809-14. doi:
10.1016/j.talanta.2008.04.037. [PMID: 18656663] - Lan Fan, Guo Wang, Lian-Sheng Wang, Yao Chen, Wei Zhang, Yuan-Fei Huang, Rui-Xue Huang, Dong-Li Hu, Dan Wang, Hong-Hao Zhou. Herbal medicine yin zhi huang induces CYP3A4-mediated sulfoxidation and CYP2C19-dependent hydroxylation of omeprazole.
Acta pharmacologica Sinica.
2007 Oct; 28(10):1685-92. doi:
10.1111/j.1745-7254.2007.00617.x. [PMID: 17883958] - Claudio F Sturino, Nicolas Lachance, Michael Boyd, Carl Berthelette, Marc Labelle, Lianhai Li, Bruno Roy, John Scheigetz, Nancy Tsou, Christine Brideau, Elizabeth Cauchon, Marie-Claude Carriere, Danielle Denis, Gillian Greig, Stacia Kargman, Sonia Lamontagne, Marie-Claude Mathieu, Nicole Sawyer, Deborah Slipetz, Gary O'Neill, Zhaoyin Wang, Robert Zamboni, Kathleen M Metters, Robert N Young. Identification of an indole series of prostaglandin D2 receptor antagonists.
Bioorganic & medicinal chemistry letters.
2006 Jun; 16(11):3043-8. doi:
10.1016/j.bmcl.2006.02.062. [PMID: 16529930] - Sebastien Dugravot, Nathalie Mondy, Nicole Mandon, Eric Thibout. Increased sulfur precursors and volatiles production by the leek Allium porrum in response to specialist insect attack.
Journal of chemical ecology.
2005 Jun; 31(6):1299-314. doi:
10.1007/s10886-005-5287-0. [PMID: 16222772] - J Clavin Kouokam, Josef Zapp, Hans Becker. Oxygen-containing sulfur-rich compounds from the bark of the tropical garlic tree Scorodophloeus zenkeri Harms.
Phytochemistry.
2002 Jun; 60(4):403-7. doi:
10.1016/s0031-9422(02)00125-5. [PMID: 12031433] - S Naito, M Nishimura. Enantioselective uptake of BOF-4272, a xanthine oxidase inhibitor with a chiral sulfoxide, by isolated rat hepatocytes.
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan.
2001 Dec; 121(12):989-94. doi:
10.1248/yakushi.121.989. [PMID: 11766411] - P Tharmapathy, M H Fukami, H Holmsen. The stimulatory effects of cationic amphiphilic drugs on human platelets treated with thrombin.
Biochemical pharmacology.
2000 Nov; 60(9):1267-77. doi:
10.1016/s0006-2952(00)00445-7. [PMID: 11008120] - M K Ellis, A G Richardson, J R Foster, F M Smith, P S Widdowson, M J Farnworth, R B Moore, M R Pitts, G A Wickramaratne. The reproductive toxicity of molinate and metabolites to the male rat: effects on testosterone and sperm morphology.
Toxicology and applied pharmacology.
1998 Jul; 151(1):22-32. doi:
10.1006/taap.1998.8371. [PMID: 9705884] - J R Cashman, S B Park, C E Berkman, L E Cashman. Role of hepatic flavin-containing monooxygenase 3 in drug and chemical metabolism in adult humans.
Chemico-biological interactions.
1995 Apr; 96(1):33-46. doi:
10.1016/0009-2797(94)03581-r. [PMID: 7720103] - C M Harris, S C Mitchell, R H Waring, G L Hendry. The case of the black-speckled dolls: an occupational hazard of unusual sulphur metabolism.
Lancet (London, England).
1986 Mar; 1(8479):492-3. doi:
10.1016/s0140-6736(86)92941-7. [PMID: 2869220] - Y FURUKAWA, M YAMAZAKI, Y OKUDA. [POLAROGRAPHIC STUDIES ON ALPHA-ETHYLTHIOISONICOTINAMIDE-SULPHOXIDE].
Kekkaku : [Tuberculosis].
1964 Dec; 39(?):527-31. doi:
NULL. [PMID: 14270664] - A W CRAIG, H JACKSON, R M JAMES. METABOLIC STUDIES WITH DI(AZIRIDIN-1-YL) SULPHOXIDE (DIETHYLENEIMINOSULPHOXIDE).
British journal of pharmacology and chemotherapy.
1963 Dec; 21(?):590-5. doi:
10.1111/j.1476-5381.1963.tb02026.x. [PMID: 14110758] - H JUNGBLUTH, H MARTIN. [On the uricosuric effect of a sulfoxide analogue of phenylbutazone].
Chemotherapia.
1961; 3(?):487-94. doi:
NULL. [PMID: 14452809] - J J BURNS, T F YU, A RITTERBAND, J M PEREL, A B GUTMAN, B B BRODIE. A potent new uricosuric agent, the sulfoxide metabolite of the phenylbutazone analogue, G-25671.
The Journal of pharmacology and experimental therapeutics.
1957 Mar; 119(3):418-26. doi:
NULL. [PMID: 13417097]
