cis-Nonachlor (BioDeep_00001868150)

Main id: BioDeep_00000012111

 


代谢物信息卡片


trans-nonachlor

化学式: C10H5Cl9 (439.7588)
中文名称: 反式－九氯标准溶液, 顺-九氯标准溶液
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C12C(C(C(C1Cl)Cl)Cl)C3(C(=C(C2(C3(Cl)Cl)Cl)Cl)Cl)Cl
InChI: InChI=1S/C10H5Cl9/c11-3-1-2(4(12)5(3)13)9(17)7(15)6(14)8(1,16)10(9,18)19/h1-5H/t1-,2+,3+,4-,5?,8+,9-

描述信息

D010575 - Pesticides > D007306 - Insecticides
D016573 - Agrochemicals

同义名列表

3 个代谢物同义名

trans-nonachlor; cis-Nonachlor; trans-Nonachlor



数据库引用编号

9 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表


文献列表

  • Jan Ove Bustnes, Bård-Jørgen Bårdsen, Børge Moe, Dorte Herzke, Manuel Ballesteros, Anette Fenstad, Katrine Borgå, Ingjerd S Krogseth, Igor Eulaers, Lovise P Skogeng, Geir W Gabrielsen, Sveinn-Are Hanssen. Impacts of a warming climate on concentrations of organochlorines in a fasting high arctic marine bird: Direct vs. indirect effects?. The Science of the total environment. 2023 Oct; 908(?):168096. doi: 10.1016/j.scitotenv.2023.168096. [PMID: 37914131]
  • Erin McDevitt, Lucie Henein, Anna Crawford, Sandeep Kondakala, Darian Young, Edward Meek, George E Howell. Alterations of Systemic and Hepatic Metabolic Function Following Exposure to Trans-nonachlor in Low and High Fat Diet Fed Male Sprague Dawley Rats. International journal of toxicology. 2023 Sep; 42(5):407-419. doi: 10.1177/10915818231170527. [PMID: 37126671]
  • M Pavuk, P F Rosenbaum, M D Lewin, T C Serio, P Rago, M C Cave, L S Birnbaum. Polychlorinated biphenyls, polychlorinated dibenzo-p-dioxins, polychlorinated dibenzofurans, pesticides, and diabetes in the Anniston Community Health Survey follow-up (ACHS II): single exposure and mixture analysis approaches. The Science of the total environment. 2023 Mar; 877(?):162920. doi: 10.1016/j.scitotenv.2023.162920. [PMID: 36934946]
  • Marion Ouidir, Pauline Mendola, Germaine M Buck Louis, Kurunthachalam Kannan, Cuilin Zhang, Fasil Tekola-Ayele. Concentrations of persistent organic pollutants in maternal plasma and epigenome-wide placental DNA methylation. Clinical epigenetics. 2020 07; 12(1):103. doi: 10.1186/s13148-020-00894-6. [PMID: 32653021]
  • Xu Han, Feng Zhang, Lingling Meng, Yuedong Xu, Yingming Li, An Li, Mary E Turyk, Ruiqiang Yang, Pu Wang, Jianqing Zhang, Qinghua Zhang, Guibin Jiang. Exposure to organochlorine pesticides and the risk of type 2 diabetes in the population of East China. Ecotoxicology and environmental safety. 2020 Mar; 190(?):110125. doi: 10.1016/j.ecoenv.2019.110125. [PMID: 31887706]
  • Edward C Meek, Dana Dale Jones, J Allen Crow, Robert W Wills, William H Cooke, Janice E Chambers. Association of serum levels of p,p'- Dichlorodiphenyldichloroethylene (DDE) with type 2 diabetes in African American and Caucasian adult men from agricultural (Delta) and non-agricultural (non-Delta) regions of Mississippi. Journal of toxicology and environmental health. Part A. 2019; 82(6):387-400. doi: 10.1080/15287394.2019.1610678. [PMID: 31064277]
  • George Eli Howell, Erin McDevitt, Lucie Henein, Charlee Mulligan, Darian Young. Alterations in cellular lipid metabolism produce neutral lipid accumulation following exposure to the organochlorine compound trans-nonachlor in rat primary hepatocytes. Environmental toxicology. 2018 Sep; 33(9):962-971. doi: 10.1002/tox.22583. [PMID: 29964320]
  • George Eli Howell, Erin McDevitt, Lucie Henein, Charlee Mulligan, Darian Young. 'Trans-nonachlor increases extracellular free fatty acid accumulation and de novo lipogenesis to produce hepatic steatosis in McArdle-RH7777 cells'. Toxicology in vitro : an international journal published in association with BIBRA. 2018 Aug; 50(?):285-292. doi: 10.1016/j.tiv.2018.04.003. [PMID: 29654899]
  • Tanya M Brown, Sarah I Lord, David W Schindler, John E Elliott. Organohalogen contaminants in common loons (Gavia immer) breeding in Western Alberta, Canada. Chemosphere. 2018 Jul; 202(?):438-445. doi: 10.1016/j.chemosphere.2018.03.107. [PMID: 29579678]
  • Josiah E Hardesty, Laila Al-Eryani, Banrida Wahlang, K Cameron Falkner, Hongxue Shi, Jian Jin, Brad J Vivace, Brian P Ceresa, Russell A Prough, Matthew C Cave. Epidermal Growth Factor Receptor Signaling Disruption by Endocrine and Metabolic Disrupting Chemicals. Toxicological sciences : an official journal of the Society of Toxicology. 2018 04; 162(2):622-634. doi: 10.1093/toxsci/kfy004. [PMID: 29329451]
  • Eliezer Brown Mwakalapa, Aviti John Mmochi, Mette Helen Bjorge Müller, Robinson Hammerthon Mdegela, Jan Ludvig Lyche, Anuschka Polder. Occurrence and levels of persistent organic pollutants (POPs) in farmed and wild marine fish from Tanzania. A pilot study. Chemosphere. 2018 Jan; 191(?):438-449. doi: 10.1016/j.chemosphere.2017.09.121. [PMID: 29054084]
  • Aleysha Thomas, Leisa-Maree Leontjew Toms, Fiona A Harden, Peter Hobson, Nicole M White, Kerrie L Mengersen, Jochen F Mueller. Concentrations of organochlorine pesticides in pooled human serum by age and gender. Environmental research. 2017 04; 154(?):10-18. doi: 10.1016/j.envres.2016.12.009. [PMID: 27992738]
  • Lee C Mangum, Lauren H Mangum, Janice E Chambers, Matthew K Ross, Edward C Meek, Robert W Wills, J Allen Crow. The association of serum trans-nonachlor levels with atherosclerosis. Journal of toxicology and environmental health. Part A. 2016; 79(5):210-20. doi: 10.1080/15287394.2016.1143901. [PMID: 26953872]
  • Rachel G Felton, Cynthia C Steiner, Barbara S Durrant, Duane H Keisler, Matthew R Milnes, Christopher W Tubbs. Identification of California Condor Estrogen Receptors 1 and 2 and Their Activation by Endocrine Disrupting Chemicals. Endocrinology. 2015 Dec; 156(12):4448-57. doi: 10.1210/en.2015-1448. [PMID: 26372180]
  • Anne-Mary Lewis-Mikhael, Rocío Olmedo-Requena, Virginia Martínez-Ruiz, Aurora Bueno-Cavanillas, José Juan Jiménez-Moleón. Organochlorine pesticides and prostate cancer, Is there an association? A meta-analysis of epidemiological evidence. Cancer causes & control : CCC. 2015 Oct; 26(10):1375-92. doi: 10.1007/s10552-015-0643-z. [PMID: 26245248]
  • Se-A Kim, Yu-Mi Lee, Ho-Won Lee, David R Jacobs, Duk-Hee Lee. Greater cognitive decline with aging among elders with high serum concentrations of organochlorine pesticides. PloS one. 2015; 10(6):e0130623. doi: 10.1371/journal.pone.0130623. [PMID: 26107947]
  • Se-A Kim, Yu-Mi Lee, Ho-Won Lee, David R Jacobs, Duk-Hee Lee. Can Inconsistent Association between Hypertension and Cognition in Elders be Explained by Levels of Organochlorine Pesticides?. PloS one. 2015; 10(12):e0144205. doi: 10.1371/journal.pone.0144205. [PMID: 26630154]
  • Colette S Azandjeme, Hélène Delisle, Benjamin Fayomi, Pierre Ayotte, Francois Djrolo, Dismand Houinato, Michèle Bouchard. High serum organochlorine pesticide concentrations in diabetics of a cotton producing area of the Benin Republic (West Africa). Environment international. 2014 Aug; 69(?):1-8. doi: 10.1016/j.envint.2014.04.002. [PMID: 24769438]
  • N Carro, J Cobas, I García, M Ignacio, A Mouteira. Distribution and trend of organochlorine pesticides in Galicia coast using mussels as bioindicator organisms. Possible relationship to biological parameters. Chemosphere. 2014 May; 102(?):37-47. doi: 10.1016/j.chemosphere.2013.12.010. [PMID: 24374186]
  • Terry F Bidleman, Gary A Stern, Gregg T Tomy, Barry T Hargrave, Liisa M Jantunen, Robie W Macdonald. Scavenging amphipods: sentinels for penetration of mercury and persistent organic chemicals into food webs of the deep Arctic Ocean. Environmental science & technology. 2013 Jun; 47(11):5553-61. doi: 10.1021/es304398j. [PMID: 23627492]
  • Pilar Suárez, Yolanda Ruiz, Ana Alonso, Fuencisla San Juan. Organochlorine compounds in mussels cultured in the Ría of Vigo: accumulation and origin. Chemosphere. 2013 Jan; 90(1):7-19. doi: 10.1016/j.chemosphere.2012.02.030. [PMID: 22391050]
  • Duk-Hee Lee, P Monica Lind, David R Jacobs, Samira Salihovic, Bert van Bavel, Lars Lind. Background exposure to persistent organic pollutants predicts stroke in the elderly. Environment international. 2012 Oct; 47(?):115-20. doi: 10.1016/j.envint.2012.06.009. [PMID: 22809777]
  • Britton Trabert, Matthew P Longnecker, John W Brock, Mark A Klebanoff, Katherine A McGlynn. Maternal pregnancy levels of trans-nonachlor and oxychlordane and prevalence of cryptorchidism and hypospadias in boys. Environmental health perspectives. 2012 Mar; 120(3):478-82. doi: 10.1289/ehp.1103936. [PMID: 21975279]
  • N Bodin, R N'Gom Ka, F Le Loc'h, J Raffray, H Budzinski, L Peluhet, L Tito de Morais. Are exploited mangrove molluscs exposed to Persistent Organic Pollutant contamination in Senegal, West Africa?. Chemosphere. 2011 Jun; 84(3):318-27. doi: 10.1016/j.chemosphere.2011.04.012. [PMID: 21550627]
  • J S Lim, H-K Son, S-K Park, D R Jacobs, D-H Lee. Inverse associations between long-term weight change and serum concentrations of persistent organic pollutants. International journal of obesity (2005). 2011 May; 35(5):744-7. doi: 10.1038/ijo.2010.188. [PMID: 20820170]
  • Duk-Hee Lee, Michael W Steffes, Andreas Sjödin, Richard S Jones, Larry L Needham, David R Jacobs. Low dose of some persistent organic pollutants predicts type 2 diabetes: a nested case-control study. Environmental health perspectives. 2010 Sep; 118(9):1235-42. doi: 10.1289/ehp.0901480. [PMID: 20444671]
  • Xiaohui Xu, Amy B Dailey, Evelyn O Talbott, Vito A Ilacqua, Greg Kearney, Nabih R Asal. Associations of serum concentrations of organochlorine pesticides with breast cancer and prostate cancer in U.S. adults. Environmental health perspectives. 2010 Jan; 118(1):60-6. doi: 10.1289/ehp.0900919. [PMID: 20056587]
  • Barbara Wyrzykowska, Ilona Bochentin, Nobuyasu Hanari, Anna Orlikowska, Jerzy Falandysz, Horii Yuichi, Nobuyoshi Yamashita. Source determination of highly chlorinated biphenyl isomers in pine needles - comparison to several PCB preparations. Environmental pollution (Barking, Essex : 1987). 2006 Sep; 143(1):46-59. doi: 10.1016/j.envpol.2005.11.018. [PMID: 16413091]
  • Duk-Hee Lee, In-Kyu Lee, Kyungeun Song, Michael Steffes, William Toscano, Beth A Baker, David R Jacobs. A strong dose-response relation between serum concentrations of persistent organic pollutants and diabetes: results from the National Health and Examination Survey 1999-2002. Diabetes care. 2006 Jul; 29(7):1638-44. doi: 10.2337/dc06-0543. [PMID: 16801591]
  • Leonard J S Tsuji, Bruce C Wainman, Ian D Martin, Jean-Philippe Weber, Celine Sutherland, J Richard Elliott, Evert Nieboer. The Mid-Canada Radar Line and First Nations' people of the James Bay region, Canada: an evaluation using log-linear contingency modelling to analyze organochlorine frequency data. Journal of environmental monitoring : JEM. 2005 Sep; 7(9):888-98. doi: 10.1039/b500524h. [PMID: 16121269]
  • Mary S Wolff, Elena Deych, Fiola Ojo, Gertrud S Berkowitz. Predictors of organochlorines in New York City pregnant women, 1998-2001. Environmental research. 2005 Feb; 97(2):170-7. doi: 10.1016/j.envres.2004.07.014. [PMID: 15533333]
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  • Judy Akkina, John Reif, Thomas Keefe, Annette Bachand. Age at natural menopause and exposure to organochlorine pesticides in Hispanic women. Journal of toxicology and environmental health. Part A. 2004 Sep; 67(18):1407-22. doi: 10.1080/15287390490483845. [PMID: 15371229]
  • H Tryphonas, G Bondy, M Hodgen, L Coady, M Parenteau, C Armstrong, S Hayward, V Liston. Effects of cis-nonachlor, trans-nonachlor and chlordane on the immune system of Sprague-Dawley rats following a 28-day oral (gavage) treatment. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2003 Jan; 41(1):107-18. doi: 10.1016/s0278-6915(02)00184-9. [PMID: 12453735]
  • G S Bondy, W H Newsome, C L Armstrong, C A Suzuki, J Doucet, S Fernie, S L Hierlihy, M M Feeley, M G Barker. trans-Nonachlor and cis-nonachlor toxicity in Sprague-Dawley rats: comparison with technical chlordane. Toxicological sciences : an official journal of the Society of Toxicology. 2000 Dec; 58(2):386-98. doi: 10.1093/toxsci/58.2.386. [PMID: 11099650]
  • T M O'Hara, M M Krahn, D Boyd, P R Becker, L M Philo. Organochlorine contaminant levels in Eskimo harvested bowhead whales of arctic Alaska. Journal of wildlife diseases. 1999 Oct; 35(4):741-52. doi: 10.7589/0090-3558-35.4.741. [PMID: 10574534]
  • A Olsson, M Vitinsh, M Plikshs, A Bergman. Halogenated environmental contaminants in perch (Perca fluviatilis) from Latvian coastal areas. The Science of the total environment. 1999 Oct; 239(1-3):19-30. doi: 10.1016/s0048-9697(99)00287-9. [PMID: 10570832]
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