Sodium diethyldithiocarbamate (BioDeep_00001867964)

Main id: BioDeep_00000014977

 


代谢物信息卡片


Sodium diethyldithiocarbamate

化学式: C5H10NNaS2 (171.015234)
中文名称: 乙硫氮
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CCN(CC)C(=S)[S-].[Na+]
InChI: /q

描述信息

D000890 - Anti-Infective Agents > D000998 - Antiviral Agents
D064449 - Sequestering Agents > D002614 - Chelating Agents
D007155 - Immunologic Factors

同义名列表

1 个代谢物同义名

Sodium diethyldithiocarbamate



数据库引用编号

8 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Rui Wang, Wenqin Song, Jie Zhu, Xinyue Shao, Chenxiao Yang, Wei Xiong, Bing Wang, Pengfei Zhao, Meiwan Chen, Yongzhuo Huang. Biomimetic nano-chelate diethyldithiocarbamate Cu/Fe for enhanced metalloimmunity and ferroptosis activation in glioma therapy. Journal of controlled release : official journal of the Controlled Release Society. 2024 Apr; 368(?):84-96. doi: 10.1016/j.jconrel.2024.02.004. [PMID: 38331004]
  • Marwa M Abu-Serie, Eisayeda Zeinab A Abdelfattah. Anti-metastatic breast cancer potential of novel nanocomplexes of diethyldithiocarbamate and green chemically synthesized iron oxide nanoparticles. International journal of pharmaceutics. 2022 Nov; 627(?):122208. doi: 10.1016/j.ijpharm.2022.122208. [PMID: 36122615]
  • Lixun Zhang, Fangxin He, Yuntao Guan. Immobilization of hexavalent chromium in contaminated soil by nano-sized layered double hydroxide intercalated with diethyldithiocarbamate: Fraction distribution, plant growth, and microbial evolution. Journal of hazardous materials. 2022 05; 430(?):128382. doi: 10.1016/j.jhazmat.2022.128382. [PMID: 35739652]
  • Marwa M Abu-Serie, Marwa Eltarahony. Novel nanoformulated diethyldithiocarbamate complexes with biosynthesized or green chemosynthesized copper oxide nanoparticles: An in vitro comparative anticancer study. International journal of pharmaceutics. 2021 Nov; 609(?):121149. doi: 10.1016/j.ijpharm.2021.121149. [PMID: 34601057]
  • Vitaly D Samuilov, Dmitry B Kiselevsky, Elena V Dzyubinskaya, Olga Yu Frolova. Effects of Superoxide Dismutase Inhibitors and Glucose on Cell Death and Generation of Reactive Oxygen Species in Pea Leaves. Biochemistry. Biokhimiia. 2021 Jul; 86(7):878-886. doi: 10.1134/s0006297921070087. [PMID: 34284711]
  • Cuiping Li, Yongli Li, Liying Lou, Xinyi Han, Huihui Wang, Tengfei Huang, Changzheng Li. The interaction between lipocalin 2 and dipyridine ketone hydrazone dithiocarbamte may influence respective function in proliferation and metastasis-related gene expressions in HepG2 cell. Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry. 2021 02; 26(1):123-133. doi: 10.1007/s00775-020-01842-8. [PMID: 33449164]
  • João Paulo Assolini, Fernanda Tomiotto-Pellissier, Bruna Taciane da Silva Bortoleti, Manoela Daiele Gonçalves, Claudia Stoeglehner Sahd, Amanda Cristina Machado Carloto, Paulo Emilio Feuser, Arthur Poester Cordeiro, Sergio Marques Borghi, Waldiceu Aparecido Verri, Claudia Sayer, Pedro Henrique Hermes de Araújo, Idessania Nazareth Costa, Ivete Conchon-Costa, Milena Menegazzo Miranda-Sapla, Wander Rogério Pavanelli. Diethyldithiocarbamate encapsulation reduces toxicity and promotes leishmanicidal effect through apoptosis-like mechanism in promastigote and ROS production by macrophage. Journal of drug targeting. 2020 12; 28(10):1110-1123. doi: 10.1080/1061186x.2020.1783669. [PMID: 32546016]
  • Seyyed Alireza Hashemi, Seyyed Mojtaba Mousavi, Sonia Bahrani, Seeram Ramakrishna, Seyyed Hamid Hashemi. Picomolar-level detection of mercury within non-biological/biological aqueous media using ultra-sensitive polyaniline-Fe3O4-silver diethyldithiocarbamate nanostructure. Analytical and bioanalytical chemistry. 2020 Sep; 412(22):5353-5365. doi: 10.1007/s00216-020-02750-1. [PMID: 32504108]
  • Raffaella Balestrini, Stefano Ghignone, Gabriela Quiroga, Valentina Fiorilli, Irene Romano, Giorgio Gambino. Long-Term Impact of Chemical and Alternative Fungicides Applied to Grapevine cv Nebbiolo on Berry Transcriptome. International journal of molecular sciences. 2020 Aug; 21(17):. doi: 10.3390/ijms21176067. [PMID: 32842492]
  • Yun Qiu, Fen Zheng, Chao Ye, Ai-Dong Chen, Jue-Jin Wang, Qi Chen, Yue-Hua Li, Yu-Ming Kang, Guo-Qing Zhu. Angiotensin Type 1 Receptors and Superoxide Anion Production in Hypothalamic Paraventricular Nucleus Contribute to Capsaicin-Induced Excitatory Renal Reflex and Sympathetic Activation. Neuroscience bulletin. 2020 May; 36(5):463-474. doi: 10.1007/s12264-019-00460-y. [PMID: 31989424]
  • Huixin Fang, Feng Luo, Pengxia Li, Qian Zhou, Xin Zhou, Baodong Wei, Shunchang Cheng, Hongsheng Zhou, Shujuan Ji. Potential of jasmonic acid (JA) in accelerating postharvest yellowing of broccoli by promoting its chlorophyll degradation. Food chemistry. 2020 Mar; 309(?):125737. doi: 10.1016/j.foodchem.2019.125737. [PMID: 31780227]
  • Hideki Ishii, Tomoteru Yamasaki, Joji Yui, Yiding Zhang, Masayuki Hanyu, Masanao Ogawa, Nobuki Nengaki, Atsushi B Tsuji, Yuya Terashima, Kouji Matsushima, Ming-Rong Zhang. Radiosynthesis of [thiocarbonyl-11C]disulfiram and its first PET study in mice. Bioorganic & medicinal chemistry letters. 2020 03; 30(6):126998. doi: 10.1016/j.bmcl.2020.126998. [PMID: 32014383]
  • Karin Luize Mazur, Paulo Emílio Feuser, Alexsandra Valério, Arthur Poester Cordeiro, Camila Indiani de Oliveira, João Paulo Assolini, Wander Rogério Pavanelli, Claudia Sayer, Pedro H H Araújo. Diethyldithiocarbamate loaded in beeswax-copaiba oil nanoparticles obtained by solventless double emulsion technique promote promastigote death in vitro. Colloids and surfaces. B, Biointerfaces. 2019 Apr; 176(?):507-512. doi: 10.1016/j.colsurfb.2018.12.048. [PMID: 30711703]
  • Wu Chen, Wen Yang, Pengyu Chen, Yongzhuo Huang, Feng Li. Disulfiram Copper Nanoparticles Prepared with a Stabilized Metal Ion Ligand Complex Method for Treating Drug-Resistant Prostate Cancers. ACS applied materials & interfaces. 2018 Dec; 10(48):41118-41128. doi: 10.1021/acsami.8b14940. [PMID: 30444340]
  • Tianhui Liu, Ping Wang, Min Cong, Xinyan Zhao, Dong Zhang, Hufeng Xu, Lin Liu, Jidong Jia, Hong You. Diethyldithiocarbamate, an anti-abuse drug, alleviates steatohepatitis and fibrosis in rodents through modulating lipid metabolism and oxidative stress. British journal of pharmacology. 2018 12; 175(24):4480-4495. doi: 10.1111/bph.14503. [PMID: 30266038]
  • Gurpreet Singh, Harkamal Kaur Sahota. Impact of benzimidazole and dithiocarbamate fungicides on the photosynthetic machinery, sugar content and various antioxidative enzymes in chickpea. Plant physiology and biochemistry : PPB. 2018 Nov; 132(?):166-173. doi: 10.1016/j.plaphy.2018.09.001. [PMID: 30195856]
  • Linpei Zhang, Yuqiu Li, Youhe Gao. Early changes in the urine proteome in a diethyldithiocarbamate-induced chronic pancreatitis rat model. Journal of proteomics. 2018 08; 186(?):8-14. doi: 10.1016/j.jprot.2018.07.015. [PMID: 30044967]
  • A F Ahmeda, M G Rae, L M Anweigi, M F Al Otaibi, A A Al-Masri, E J Johns. The effect of superoxide dismutase enzyme inhibition on renal microcirculation of spontaneously hypertensive-stroke prone and Wistar rats. Physiological research. 2018 08; 67(4):535-541. doi: 10.33549/physiolres.933655. [PMID: 29750873]
  • Vaibhav G Sheth, Umashanker Navik, Krishna Prahlad Maremanda, Gopabandhu Jena. Effect of diethyldithiocarbamate in cyclophosphamide-induced nephrotoxicity: Immunohistochemical study of superoxide dismutase 1 in rat. Indian journal of pharmacology. 2018 Jan; 50(1):4-11. doi: 10.4103/ijp.ijp_850_16. [PMID: 29861522]
  • Ke Zhang, Ruixia Dong, Kang Sun, Xiaoxiao Wang, Jiajia Wang, Chung S Yang, Jinsong Zhang. Synergistic toxicity of epigallocatechin-3-gallate and diethyldithiocarbamate, a lethal encounter involving redox-active copper. Free radical biology & medicine. 2017 12; 113(?):143-156. doi: 10.1016/j.freeradbiomed.2017.09.027. [PMID: 28974447]
  • Ardeshir Shokrollahi, Foroogh Ebrahimi. Supramolecular-Based Ultrasonic-Assisted Dispersion Solidification Liquid-Liquid Microextraction of Copper and Cobalt Prior to Their Flame Atomic Absorption Spectrometry Determination. Journal of AOAC International. 2017 Nov; 100(6):1861-1868. doi: 10.5740/jaoacint.17-0042. [PMID: 28807089]
  • Tae Gyu Nam, Bong Han Lee, Hyo-Kyoung Choi, Ahmad Rois Mansur, Sang Gil Lee, Dae-Ok Kim. Rhus verniciflua Stokes Extract and Its Flavonoids Protect PC-12 Cells against H2O2-Induced Cytotoxicity. Journal of microbiology and biotechnology. 2017 Jun; 27(6):1090-1097. doi: 10.4014/jmb.1612.12018. [PMID: 28376611]
  • Lingmei Sun, Kai Liao, Chengcheng Hang, Dayong Wang. Honokiol induces reactive oxygen species-mediated apoptosis in Candida albicans through mitochondrial dysfunction. PloS one. 2017; 12(2):e0172228. doi: 10.1371/journal.pone.0172228. [PMID: 28192489]
  • Mohamed Wehbe, Malathi Anantha, Minghan Shi, Ada Wai-Yin Leung, Wieslawa H Dragowska, Léon Sanche, Marcel B Bally. Development and optimization of an injectable formulation of copper diethyldithiocarbamate, an active anticancer agent. International journal of nanomedicine. 2017; 12(?):4129-4146. doi: 10.2147/ijn.s137347. [PMID: 28615941]
  • Hadi Kahe, Mahmoud Chamsaz. A new supramolecular based liquid solid microextraction method for preconcentration and determination of trace bismuth in human blood serum and hair samples by electrothermal atomic absorption spectrometry. Environmental monitoring and assessment. 2016 Nov; 188(11):601. doi: 10.1007/s10661-016-5613-8. [PMID: 27699649]
  • Anjana Bali, Amteshwar Singh Jaggi. Investigations on GSK-3β/NF-kB signaling in stress and stress adaptive behavior in electric foot shock subjected mice. Behavioural brain research. 2016 Apr; 302(?):1-10. doi: 10.1016/j.bbr.2016.01.014. [PMID: 26778780]
  • Koukou Li, Min Yu, Yang Hu, Guangming Ren, Tingting Zang, Xiuhong Xu, Juanjuan Qu. Three kinds of Ganoderma lucidum polysaccharides attenuate DDC-induced chronic pancreatitis in mice. Chemico-biological interactions. 2016 Mar; 247(?):30-8. doi: 10.1016/j.cbi.2016.01.013. [PMID: 26826268]
  • Sundar R Koyyalamudi, Unnikrishnan Kuzhiumparambil, Christa E Nath, Jennifer A Byrne, Christopher J Fraser, Tracey A O'Brien, John W Earl, Peter J Shaw. Development and Validation of a High Pressure Liquid Chromatography-UV Method for the Determination of Treosulfan and Its Epoxy Metabolites in Human Plasma and Its Application in Pharmacokinetic Studies. Journal of chromatographic science. 2016 Mar; 54(3):326-33. doi: 10.1093/chromsci/bmv145. [PMID: 26433392]
  • Winka Le Clec'h, Timothy J C Anderson, Frédéric D Chevalier. Characterization of hemolymph phenoloxidase activity in two Biomphalaria snail species and impact of Schistosoma mansoni infection. Parasites & vectors. 2016 Jan; 9(?):32. doi: 10.1186/s13071-016-1319-6. [PMID: 26797101]
  • Mohamed Wehbe, Malathi Anantha, Ian Backstrom, Ada Leung, Kent Chen, Armaan Malhotra, Katarina Edwards, Marcel B Bally. Nanoscale Reaction Vessels Designed for Synthesis of Copper-Drug Complexes Suitable for Preclinical Development. PloS one. 2016; 11(4):e0153416. doi: 10.1371/journal.pone.0153416. [PMID: 27055237]
  • Michalis Petropoulos, Georgia Karamolegkou, Eleftheria Rosmaraki, Sotiris Tsakas. Hydrogen peroxide signals E. coli phagocytosis by human polymorphonuclear cells; up-stream and down-stream pathway. Redox biology. 2015 Dec; 6(?):100-105. doi: 10.1016/j.redox.2015.07.004. [PMID: 26204503]
  • Ying Liu, Man He, Beibei Chen, Bin Hu. Simultaneous speciation of inorganic arsenic, selenium and tellurium in environmental water samples by dispersive liquid liquid microextraction combined with electrothermal vaporization inductively coupled plasma mass spectrometry. Talanta. 2015 Sep; 142(?):213-20. doi: 10.1016/j.talanta.2015.04.050. [PMID: 26003714]
  • Zebalda D Bamji, Kareem N Washington, Emmanuel Akinboye, Oladapo Bakare, Yasmine M Kanaan, Robert L Copeland. Apoptotic Effects of Novel Dithiocarbamate Analogs of Emetine in Prostate Cancer Cell Lines. Anticancer research. 2015 Sep; 35(9):4723-32. doi: ". [PMID: 26254362]
  • Mitsuhiro Matsuo, Joy Michal Johnson, Ayaka Hieno, Mutsutomo Tokizawa, Mika Nomoto, Yasuomi Tada, Rinesh Godfrey, Junichi Obokata, Irena Sherameti, Yoshiharu Y Yamamoto, Frank-D Böhmer, Ralf Oelmüller. High REDOX RESPONSIVE TRANSCRIPTION FACTOR1 Levels Result in Accumulation of Reactive Oxygen Species in Arabidopsis thaliana Shoots and Roots. Molecular plant. 2015 Aug; 8(8):1253-73. doi: 10.1016/j.molp.2015.03.011. [PMID: 25882345]
  • Irina Drobinskaya, Felix Neumaier, Alexey Pereverzev, Jürgen Hescheler, Toni Schneider. Diethyldithiocarbamate-mediated zinc ion chelation reveals role of Cav2.3 channels in glucagon secretion. Biochimica et biophysica acta. 2015 May; 1853(5):953-64. doi: 10.1016/j.bbamcr.2015.01.001. [PMID: 25603538]
  • Daniela Vullo, Emmanouil Flemetakis, Andrea Scozzafava, Clemente Capasso, Claudiu T Supuran. Anion inhibition studies of two α-carbonic anhydrases from Lotus japonicus, LjCAA1 and LjCAA2. Journal of inorganic biochemistry. 2014 Jul; 136(?):67-72. doi: 10.1016/j.jinorgbio.2014.03.014. [PMID: 24769135]
  • Surbhi Gupta, Bhupesh Sharma. Pharmacological benefit of I(1)-imidazoline receptors activation and nuclear factor kappa-B (NF-κB) modulation in experimental Huntington's disease. Brain research bulletin. 2014 Mar; 102(?):57-68. doi: 10.1016/j.brainresbull.2014.02.007. [PMID: 24582883]
  • Panchanand Mishra, Anshuman Dixit, Mamata Ray, Surendra Chandra Sabat. Mechanistic study of CuZn-SOD from Ipomoea carnea mutated at dimer interface: enhancement of peroxidase activity upon monomerization. Biochimie. 2014 Feb; 97(?):181-93. doi: 10.1016/j.biochi.2013.10.014. [PMID: 24513093]
  • Kayoko Minakata, Hideki Nozawa, Itaru Yamagishi, Kunio Gonmori, Masako Suzuki, Koutaro Hasegawa, Amin Wurita, Kanako Watanabe, Osamu Suzuki. MALDI-Q-TOF mass spectrometric determination of gold and platinum in tissues using their diethyldithiocarbamate chelate complexes. Analytical and bioanalytical chemistry. 2014 Feb; 406(5):1331-8. doi: 10.1007/s00216-013-6838-9. [PMID: 23455689]
  • Valfredo Azevedo Lemos, Emanuel Vitor dos Santos Vieira. Method for the determination of cadmium, lead, nickel, cobalt and copper in seafood after dispersive liquid-liquid micro-extraction. Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment. 2014; 31(11):1872-8. doi: 10.1080/19440049.2014.964338. [PMID: 25224724]
  • Beata Krasnodębska-Ostręga, Monika Sadowska, Katarzyna Piotrowska, Marta Wojda. Thallium (III) determination in the Baltic seawater samples by ICP MS after preconcentration on SGX C18 modified with DDTC. Talanta. 2013 Aug; 112(?):73-9. doi: 10.1016/j.talanta.2013.03.059. [PMID: 23708540]
  • Saber Sakr, Ayman El-Kenawy, Doaa El-Sahra. Metiram-induced nephrotoxicity in albino mice: effect of licorice aqueous extract. Environmental toxicology. 2013 Jul; 28(7):372-9. doi: 10.1002/tox.20728. [PMID: 21544926]
  • Katrijn De Brucker, Anna Bink, Els Meert, Bruno P A Cammue, Karin Thevissen. Potentiation of antibiofilm activity of amphotericin B by superoxide dismutase inhibition. Oxidative medicine and cellular longevity. 2013; 2013(?):704654. doi: 10.1155/2013/704654. [PMID: 24078861]
  • I Rahden-Staroń, E Grosicka-Maciąg, D Kurpios-Piec, H Czeczot, T Grzela, M Szumiło. The effects of sodium diethyldithiocarbamate in fibroblasts V79 cells in relation to cytotoxicity, antioxidative enzymes, glutathione, and apoptosis. Archives of toxicology. 2012 Dec; 86(12):1841-50. doi: 10.1007/s00204-012-0909-0. [PMID: 22872140]
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  • Bhupesh Sharma, Nirmal Singh. Defensive effect of natrium diethyldithiocarbamate trihydrate (NDDCT) and lisinopril in DOCA-salt hypertension-induced vascular dementia in rats. Psychopharmacology. 2012 Oct; 223(3):307-17. doi: 10.1007/s00213-012-2718-9. [PMID: 22526544]
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  • Xueqin Guo, Man He, Beibei Chen, Bin Hu. Solidified floating organic drop microextraction combined with ETV-ICP-MS for the determination of trace heavy metals in environmental water samples. Talanta. 2012 May; 94(?):70-6. doi: 10.1016/j.talanta.2012.02.053. [PMID: 22608416]
  • Laetitia Knockaert, Alain Berson, Catherine Ribault, Pierre-Emmanuel Prost, Alain Fautrel, Julie Pajaud, Sylvie Lepage, Catherine Lucas-Clerc, Jean-Marc Bégué, Bernard Fromenty, Marie-Anne Robin. Carbon tetrachloride-mediated lipid peroxidation induces early mitochondrial alterations in mouse liver. Laboratory investigation; a journal of technical methods and pathology. 2012 Mar; 92(3):396-410. doi: 10.1038/labinvest.2011.193. [PMID: 22157718]
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  • Olga M Viquez, Barry Lai, Jae Hee Ahn, Mark D Does, Holly L Valentine, William M Valentine. N,N-diethyldithiocarbamate promotes oxidative stress prior to myelin structural changes and increases myelin copper content. Toxicology and applied pharmacology. 2009 Aug; 239(1):71-9. doi: 10.1016/j.taap.2009.05.017. [PMID: 19467251]
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  • Holly L Valentine, Olga M Viquez, Kalyani Amarnath, Venkataraman Amarnath, Justin Zyskowski, Endalkachew N Kassa, William M Valentine. Nitrogen substituent polarity influences dithiocarbamate-mediated lipid oxidation, nerve copper accumulation, and myelin injury. Chemical research in toxicology. 2009 Jan; 22(1):218-26. doi: 10.1021/tx8003714. [PMID: 19093748]
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  • S M Talebi, M Malekiha. Simultaneous determination of trace heavy metals in ambient aerosols by inductively coupled plasma atomic emission spectrometry after pre-concentration with sodium diethyldithiocarbamate. Journal of environmental science & engineering. 2008 Jul; 50(3):197-202. doi: NULL. [PMID: 19552073]
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