N,N-DIMETHYLACETAMIDE (BioDeep_00001867720)
Main id: BioDeep_00000013385
Volatile Flavor Compounds
代谢物信息卡片
N,N-DIMETHYLACETAMIDE
化学式: C4H9NO (87.0684104)
中文名称: N,N-二甲基乙酰胺(DMAC), N,N-二甲基乙酰胺
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC(=O)N(C)C
InChI: InChI=1S/C4H9NO/c1-4(6)5(2)3/h1-3H3
描述信息
A member of the class of acetamides that is acetamide in which the hydrogens attached to the N atom have been replaced by two methyl groups respectively. Metabolite observed in cancer metabolism.
D020011 - Protective Agents > D003451 - Cryoprotective Agents
同义名列表
2 个代谢物同义名
数据库引用编号
8 个数据库交叉引用编号
- ChEBI: CHEBI:84254
- KEGG: C20339
- PubChem: 31374
- ChEMBL: CHEMBL11873
- CAS: 127-19-5
- MetaboLights: MTBLC84254
- PubChem: 163312077
- PDB-CCD: 5Y9
分类词条
相关代谢途径
Reactome(0)
BioCyc(7)
- NADH to cytochrome bo oxidase electron transfer I
- succinate to cytochrome bo oxidase electron transfer
- NADH to cytochrome bo oxidase electron transfer II
- D-lactate to cytochrome bo oxidase electron transfer
- glycerol-3-phosphate to cytochrome bo oxidase electron transfer
- proline to cytochrome bo oxidase electron transfer
- pyruvate to cytochrome bo oxidase electron transfer
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- O Varisli, F Bozkaya, N Aydilek, A Taskin. Relationship between toxicity of cryoprotectants, osmotic and oxidative stresses in awassi ram sperm.
Cryo letters.
2022 Mar; 43(2):120-128. doi:
". [PMID: 36626153] - N L S Gatti, C D Corcini, J S Filho, S L Soares, A N Anciuti, R M Barbosa, N W Knabah, A T Tavares, D C Bongalhardo, A S Varela Junior. Dimethylacetamide in Rooster Semen Cryopreservation.
Cryo letters.
2021 Jan; 42(1):39-43. doi:
NULL. [PMID: 33973991] - Shinobu Yamamoto, Akito Takeuchi, Yuichiro Yoshida, Osamu Nishinoiri, Masayoshi Ichiba, Hiroyuki Miyauchi. Assessment of dermal exposure to N,N-dimethylacetamide in spray workers by combining personal exposure monitoring, biological monitoring, and glove permeation monitoring: A pilot study.
Journal of occupational health.
2021 Jan; 63(1):e12265. doi:
10.1002/1348-9585.12265. [PMID: 34390065] - Yasin Orooji, Ehsan Ghasali, Nahid Emami, Fatemeh Noorisafa, Amir Razmjou. ANOVA Design for the Optimization of TiO2 Coating on Polyether Sulfone Membranes.
Molecules (Basel, Switzerland).
2019 Aug; 24(16):. doi:
10.3390/molecules24162924. [PMID: 31409035] - Shinobu Yamamoto, Akiko Matsumoto, Yuko Yui, Shota Miyazaki, Shinji Kumagai, Hajime Hori, Masayoshi Ichiba. Concentration determination of urinary metabolites of N,N-dimethylacetamide by high-performance liquid chromatography-tandem mass spectrometry.
Journal of occupational health.
2018 Mar; 60(2):140-147. doi:
10.1539/joh.17-0098-oa. [PMID: 29213009] - B A Rakha, M S Ansari, S Akhter, Z Zafar, A Naseer, I Hussain, J Santiago-Moreno, E Blesbois. Dimethyleacetamide improves the cryosurvivability of Indian red jungle fowl (Gallus gallus murghi) sperm.
Theriogenology.
2017 Nov; 103(?):83-89. doi:
10.1016/j.theriogenology.2017.07.018. [PMID: 28779613] - Mildred Cendana, Samiuela Lee, Parth J Upadhyay, Jennifer A Byrne, Peter J Shaw, John Earl, Christa E Nath. An HPLC-UV method for determining plasma dimethylacetamide concentrations in patients receiving intravenous busulfan.
Biomedical chromatography : BMC.
2017 Jul; 31(7):. doi:
10.1002/bmc.3906. [PMID: 27925250] - Afshin Seifi-Jamadi, Ejaz Ahmad, Mahdi Ansari, Hamid Kohram. Antioxidant effect of quercetin in an extender containing DMA or glycerol on freezing capacity of goat semen.
Cryobiology.
2017 04; 75(?):15-20. doi:
10.1016/j.cryobiol.2017.03.002. [PMID: 28279680] - Juliana P Alves, Carine D Corcini, Estela F Silva, Josie S Caldas, Tainã F Cardoso, Sergio R N Piedras, Rodrigo D Jardim, Antonio S Varela. The role of amides in seminal cryopreservation of wild silverside, Odontesthes bonariensis.
Cryobiology.
2016 12; 73(3):383-387. doi:
10.1016/j.cryobiol.2016.09.001. [PMID: 27609248] - Patricia N Banfor, Gary A Gintant, John M Lipari, Philip D Zocharski. A novel intravenous vehicle for preclinical cardiovascular screening of small molecule drug candidates in rat.
Journal of pharmacological and toxicological methods.
2016 Nov; 82(?):62-67. doi:
10.1016/j.vascn.2016.07.002. [PMID: 27432021] - Anna Shaliutina-Kolešová, Jacky Cosson, Ievgen Lebeda, Ievgenia Gazo, Olena Shaliutina, Boris Dzyuba, Otomar Linhart. The influence of cryoprotectants on sturgeon (Acipenser ruthenus) sperm quality, DNA integrity, antioxidant responses, and resistance to oxidative stress.
Animal reproduction science.
2015 Aug; 159(?):66-76. doi:
10.1016/j.anireprosci.2015.05.014. [PMID: 26089085] - Julie A Long, Phillip H Purdy, Kees Zuidberg, Sipke-Joost Hiemstra, Sandra G Velleman, Henri Woelders. Cryopreservation of turkey semen: effect of breeding line and freezing method on post-thaw sperm quality, fertilization, and hatching.
Cryobiology.
2014 Jun; 68(3):371-8. doi:
10.1016/j.cryobiol.2014.04.003. [PMID: 24731850] - Kornelius Kerl, Christian Diestelhorst, Imke Bartelink, Jaap Boelens, Mirjam N Trame, Joachim Boos, Georg Hempel. Evaluation of effects of busulfan and DMA on SOS in pediatric stem cell recipients.
Pediatric blood & cancer.
2014 Feb; 61(2):306-11. doi:
10.1002/pbc.24827. [PMID: 24174393] - Mirjam N Trame, Imke H Bartelink, Joachim Boos, Jaap J Boelens, Georg Hempel. Population pharmacokinetics of dimethylacetamide in children during standard and once-daily IV busulfan administration.
Cancer chemotherapy and pharmacology.
2013 Nov; 72(5):1149-55. doi:
10.1007/s00280-013-2284-9. [PMID: 24036908] - Stephen D Johnston, Yeng Peng Zee, Carmen López-Fernández, Jamie Gosálvez. The effect of chilled storage and cryopreservation on the sperm DNA fragmentation dynamics of a captive population of koalas.
Journal of andrology.
2012 Sep; 33(5):1007-15. doi:
10.2164/jandrol.111.015248. [PMID: 22282436] - Suna He, Zheng Cui, Dong Mei, Hua Zhang, Xueqing Wang, Wenbing Dai, Qiang Zhang. A cremophor-free self-microemulsified delivery system for intravenous injection of teniposide: evaluation in vitro and in vivo.
AAPS PharmSciTech.
2012 Sep; 13(3):846-52. doi:
10.1208/s12249-012-9809-0. [PMID: 22644709] - Ya-lin Qian, Cheng-min Xu, Yan-yan Lu, Hong-fan Tang, Zheng Ruan, Han Wang, Hai-bao Zhu, Dan-hua Liu, Xin Zhang. [Biological limit value for occupational exposure to N, N-dimethylacetamide].
Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases.
2012 Sep; 30(9):709-11. doi:
NULL. [PMID: 23257108] - Agnieszka Partyka, Ewa Łukaszewicz, Wojciech Niżański. Effect of cryopreservation on sperm parameters, lipid peroxidation and antioxidant enzymes activity in fowl semen.
Theriogenology.
2012 May; 77(8):1497-504. doi:
10.1016/j.theriogenology.2011.11.006. [PMID: 22225691] - Steve Silvester, Frank Zang. Overcoming non-specific adsorption issues for AZD9164 in human urine samples: consideration of bioanalytical and metabolite identification procedures.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2012 Apr; 893-894(?):134-43. doi:
10.1016/j.jchromb.2012.03.004. [PMID: 22440890] - Aliaksei Dubavik, Erdinc Sezgin, Vladimir Lesnyak, Nikolai Gaponik, Petra Schwille, Alexander Eychmüller. Penetration of amphiphilic quantum dots through model and cellular plasma membranes.
ACS nano.
2012 Mar; 6(3):2150-6. doi:
10.1021/nn204930y. [PMID: 22303822] - Andrew G Netting, Julian C Theobald, Ian C Dodd. Xylem sap collection and extraction methodologies to determine in vivo concentrations of ABA and its bound forms by gas chromatography-mass spectrometry (GC-MS).
Plant methods.
2012 Mar; 8(?):11. doi:
10.1186/1746-4811-8-11. [PMID: 22439865] - Deepak Singodia, Ashwni Verma, Prashant Khare, Anuradha Dube, Kalyan Mitra, Prabhat Ranjan Mishra. Investigations on feasibility of in situ development of amphotericin B liposomes for industrial applications.
Journal of liposome research.
2012 Mar; 22(1):8-17. doi:
10.3109/08982104.2011.584317. [PMID: 21682670] - Jin Young Kim, Jung Yeon Ghee, Sun Woo Lim, Shang Guo Piao, Byung Ha Chung, Hye Eun Yoon, Hyeon Seok Hwang, Bum Soon Choi, Jin Kim, Chul Woo Yang. Comparison of early and late conversion of sirolimus in experimental model of chronic cyclosporine nephropathy.
Journal of Korean medical science.
2012 Feb; 27(2):160-9. doi:
10.3346/jkms.2012.27.2.160. [PMID: 22323863] - Huimin Qi, Xiaolei Liu, Jinbao Zhang, Yu Duan, Xiaolan Wang, Quanbin Zhang. Synthesis and antihyperlipidemic activity of acetylated derivative of ulvan from Ulva pertusa.
International journal of biological macromolecules.
2012 Jan; 50(1):270-2. doi:
10.1016/j.ijbiomac.2011.11.006. [PMID: 22115715] - Devendra Kumar, Ashok K Khanna, Ram Pratap, Jitendra K Sexana, Rabi S Bhatta. Dose escalation pharmacokinetics and lipid lowering activity of a novel farnesoid X receptor modulator: 16-Dehydropregnenolone.
Indian journal of pharmacology.
2012 Jan; 44(1):57-62. doi:
10.4103/0253-7613.91868. [PMID: 22345871] - Chong Shen, Guoliang Zhang, Qin Meng. Regulation of epithelial cell morphology and functions approaching to more in vivo-like by modifying polyethylene glycol on polysulfone membranes.
PloS one.
2012; 7(4):e36110. doi:
10.1371/journal.pone.0036110. [PMID: 22558349] - Sergey A Staroverov, Vladimir A Sidorkin, Alexander S Fomin, Sergey Yu Shchyogolev, Lev A Dykman. Biodynamic parameters of micellar diminazene in sheep erythrocytes and blood plasma.
Journal of veterinary science.
2011 Dec; 12(4):303-7. doi:
10.4142/jvs.2011.12.4.303. [PMID: 22122895] - Yan-yan Lu, Hao Wu, Hong-fang Tang, Zheng Ruan, Dan-hua Liu, Cheng-min Xu, Ya-ling Qian. [The impact of N, N-dimethylacetamide on the health of workers].
Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases.
2011 Nov; 29(11):834-6. doi:
NULL. [PMID: 22368810] - Nicolaia Iaffaldano, Luca Romagnoli, Angelo Manchisi, Maria Pina Rosato. Cryopreservation of turkey semen by the pellet method: effects of variables such as the extender, cryoprotectant concentration, cooling time and warming temperature on sperm quality determined through principal components analysis.
Theriogenology.
2011 Sep; 76(5):794-801. doi:
10.1016/j.theriogenology.2011.04.012. [PMID: 21664665] - J Santiago-Moreno, C Castaño, A Toledano-Díaz, M A Coloma, A López-Sebastián, M T Prieto, J L Campo. Semen cryopreservation for the creation of a Spanish poultry breeds cryobank: optimization of freezing rate and equilibration time.
Poultry science.
2011 Sep; 90(9):2047-53. doi:
10.3382/ps.2011-01355. [PMID: 21844272] - Fen Ran, Shengqiang Nie, Weifeng Zhao, Jie Li, Baihai Su, Shudong Sun, Changsheng Zhao. Biocompatibility of modified polyethersulfone membranes by blending an amphiphilic triblock co-polymer of poly(vinyl pyrrolidone)-b-poly(methyl methacrylate)-b-poly(vinyl pyrrolidone).
Acta biomaterialia.
2011 Sep; 7(9):3370-81. doi:
10.1016/j.actbio.2011.05.026. [PMID: 21658478] - Tiago Collares, Vinicius Farias Campos, Priscila Marques De Leon, Paulo V Cavalcanti, Marta G Amaral, Odir A Dellagostin, Joao Carlos Deschamps, Fabiana K Seixas. Transgene transmission in chickens by sperm-mediated gene transfer after seminal plasma removal and exogenous DNA treated with dimethylsulfoxide or N,N-dimethylacetamide.
Journal of biosciences.
2011 Sep; 36(4):613-20. doi:
10.1007/s12038-011-9098-x. [PMID: 21857108] - Agnieszka Partyka, Ewa Lukaszewicz, Wojciech Niżański, Jan Twardoń. Detection of lipid peroxidation in frozen-thawed avian spermatozoa using C(11)-BODIPY(581/591).
Theriogenology.
2011 Jun; 75(9):1623-9. doi:
10.1016/j.theriogenology.2011.01.002. [PMID: 21396693] - Hyoung Ryoul Kim, Tae Woo Kim. Occupational hepatic disorders in Korea.
Journal of Korean medical science.
2010 Dec; 25(Suppl):S36-40. doi:
10.3346/jkms.2010.25.s.s36. [PMID: 21258588] - E Mocé, I Grasseau, E Blesbois. Cryoprotectant and freezing-process alter the ability of chicken sperm to acrosome react.
Animal reproduction science.
2010 Dec; 122(3-4):359-66. doi:
10.1016/j.anireprosci.2010.10.010. [PMID: 21115311] - Andrea Princivalle, Francesco Pasini, Luigi Perbellini. S-(acetamidomethyl)mercapturic acid (AMMA): a new biomarker for occupational exposure to N,N-dimethylacetamide.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2010 Oct; 878(27):2515-9. doi:
10.1016/j.jchromb.2010.04.022. [PMID: 20462811] - George Shigueki Yasui, Lenin Arias-Rodriguez, Takafumi Fujimoto, Katsutoshi Arai. A sperm cryopreservation protocol for the loach Misgurnus anguillicaudatus and its applicability for other related species.
Animal reproduction science.
2009 Dec; 116(3-4):335-45. doi:
10.1016/j.anireprosci.2009.02.021. [PMID: 19446413] - P H Purdy, Y Song, F G Silversides, H D Blackburn. Evaluation of glycerol removal techniques, cryoprotectants, and insemination methods for cryopreserving rooster sperm with implications of regeneration of breed or line or both.
Poultry science.
2009 Oct; 88(10):2184-91. doi:
10.3382/ps.2008-00402. [PMID: 19762874] - Yeng Peng Zee, William V Holt, Vere Nicolson, Michael Pyne, Stephen D Johnston. Individual variability in post-thaw sperm survival in a captive koala population.
Cryobiology.
2009 Aug; 59(1):69-74. doi:
10.1016/j.cryobiol.2009.04.010. [PMID: 19426724] - Rana Rais, Pablo M Gonzalez, Xiaowan Zheng, Stephen A Wring, James E Polli. Method to screen substrates of apical sodium-dependent bile acid transporter.
The AAPS journal.
2008 Dec; 10(4):596-605. doi:
10.1208/s12248-008-9069-9. [PMID: 19085111] - Rhett McClean, Yeng Peng Zee, William V Holt, Stephen D Johnston. Cryopreservation of kangaroo spermatozoa using alternative approaches that reduce cytotoxic exposure to glycerol.
Cryobiology.
2008 Dec; 57(3):304-7. doi:
10.1016/j.cryobiol.2008.08.007. [PMID: 18822280] - Jaime A Yáñez, M Laird Forrest, Yusuke Ohgami, Glen S Kwon, Neal M Davies. Pharmacometrics and delivery of novel nanoformulated PEG-b-poly(epsilon-caprolactone) micelles of rapamycin.
Cancer chemotherapy and pharmacology.
2008 Jan; 61(1):133-44. doi:
10.1007/s00280-007-0458-z. [PMID: 17393166] - Yeng Peng Zee, William V Holt, Jaime Gosalvez, Camryn D Allen, Vere Nicolson, Michael Pyne, Michelle Burridge, Frank N Carrick, Stephen D Johnston. Dimethylacetamide can be used as an alternative to glycerol for the successful cryopreservation of koala (Phascolarctos cinereus) spermatozoa.
Reproduction, fertility, and development.
2008; 20(6):724-33. doi:
10.1071/rd08036. [PMID: 18671920] - Nicolas Jullien, Isabelle Goddard, Samia Selmi-Ruby, Jean-Luc Fina, Harold Cremer, Jean-Paul Herman. Conditional transgenesis using Dimerizable Cre (DiCre).
PloS one.
2007 Dec; 2(12):e1355. doi:
10.1371/journal.pone.0001355. [PMID: 18159238] - G Tranfo, D Pigini, G Federici, S Bernardini, C Perricone, R Perricone. [Feasibility study of biological monitoring of chemical agents by means of evaluation of the effects on their in vitro effects on the complement system].
Giornale italiano di medicina del lavoro ed ergonomia.
2007 Jul; 29(3 Suppl):520-2. doi:
NULL. [PMID: 18409809] - M Borel, F Degoul, Y Communal, E Mounetou, B Bouchon, R C-Gaudreault, J C Madelmont, E Miot-Noirault. N-(4-iodophenyl)-N'-(2-chloroethyl)urea as a microtubule disrupter: in vitro and in vivo profiling of antitumoral activity on CT-26 murine colon carcinoma cell line cultured and grafted to mice.
British journal of cancer.
2007 Jun; 96(11):1684-91. doi:
10.1038/sj.bjc.6603778. [PMID: 17486131] - Sang-Jae Jung, Chae-Yong Lee, Seong-Ah Kim, Ki-Soo Park, Bong-Goo Ha, Jinseok Kim, Jay-Young Yu, Taesung Choi. Dimethylacetamide-induced hepatic injuries among spandex fibre workers.
Clinical toxicology (Philadelphia, Pa.).
2007 Jun; 45(5):435-9. doi:
10.1080/15563650601117897. [PMID: 17503240] - Georg Hempel, Doris Oechtering, Claudia Lanvers-Kaminsky, Thomas Klingebiel, Josef Vormoor, Bernd Gruhn, Joachim Boos. Cytotoxicity of dimethylacetamide and pharmacokinetics in children receiving intravenous busulfan.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
2007 May; 25(13):1772-8. doi:
10.1200/jco.2006.08.8807. [PMID: 17470868] - Takayuki Kawamoto, Teruyoshi Narita, Kiyoshi Isowa, Hideo Aoki, Masahiro Hayashi, Akira Komaru, Hiromi Ohta. Effects of cryopreservation methods on post-thaw motility of spermatozoa from the Japanese pearl oyster, Pinctada fucata martensii.
Cryobiology.
2007 Feb; 54(1):19-26. doi:
10.1016/j.cryobiol.2006.10.190. [PMID: 17174293] - Hae-Kwan Cheong, Eun A Kim, Jung-Keun Choi, Sung-Bong Choi, Jeong-Ill Suh, Dae Seob Choi, Jung Ran Kim. Grand rounds: an outbreak of toxic hepatitis among industrial waste disposal workers.
Environmental health perspectives.
2007 Jan; 115(1):107-12. doi:
10.1289/ehp.8951. [PMID: 17366828] - Doris Oechtering, Joachim Boos, Georg Hempel. Monitoring of N,N-dimethylacetamide in children during i.v.-busulfan therapy by liquid chromatography-mass spectrometry.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2006 Jul; 838(2):129-34. doi:
10.1016/j.jchromb.2006.04.034. [PMID: 16725388] - Hirokazu Okuda, Tetsuya Takeuchi, Hideki Senoh, Heihachiro Arito, Kasuke Nagano, Seigo Yamamoto, Taijiro Matsushima. Developmental toxicity induced by inhalation exposure of pregnant rats to N,N-dimethylacetamide.
Journal of occupational health.
2006 May; 48(3):154-60. doi:
10.1539/joh.48.154. [PMID: 16788275] - Yuan Xu, Qing Shen. Dynamic dissolution of persimmon leaves in DMSO and DMAc and the influence of acid-base interactions.
Colloids and surfaces. B, Biointerfaces.
2006 Jan; 47(1):98-101. doi:
10.1016/j.colsurfb.2005.11.027. [PMID: 16406493] - Gaye R Ruble, Odessa Z Giardino, Stewart L Fossceco, Dennis Cosmatos, Richard J Knapp, Norman J Barlow. The effect of commonly used vehicles on canine hematology and clinical chemistry values.
Journal of the American Association for Laboratory Animal Science : JAALAS.
2006 Jan; 45(1):25-9. doi:
NULL. [PMID: 16539331] - Susan Weng Larsen, Michael Ankersen, Claus Larsen. Kinetics of degradation and oil solubility of ester prodrugs of a model dipeptide (Gly-Phe).
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.
2004 Aug; 22(5):399-408. doi:
10.1016/j.ejps.2004.04.013. [PMID: 15265509] - Hirobumi Takahashi, Norikazu Ohtake, Toshihiro Sakamoto, Tomoharu Iino, Nobuhiko Kawanishi, Masayuki Nakamura, Takashi Yoshizumi, Kenji Niiyama, Satoshi Ozaki, Hiromasa Okada, Akiko Kano, Hiroyuki Takahashi, Yasuyuki Ishii, Megumu Okada, Michiyasu Saito, Yoshio Sawazaki, Takashi Hayama, Masaru Nishikibe. Structure-activity relationships of a novel class of endothelin receptor selective antagonists; 6-carboxy-2-isopropylamino-5,7-diarylcyclopenteno[1,2-b]pyridines.
Bioorganic & medicinal chemistry letters.
2004 Mar; 14(6):1503-7. doi:
10.1016/j.bmcl.2004.01.008. [PMID: 15006391] - Omathanu Pillai, Vinod Nair, Ramesh Panchagnula. Transdermal iontophoresis of insulin: IV. Influence of chemical enhancers.
International journal of pharmaceutics.
2004 Jan; 269(1):109-20. doi:
10.1016/j.ijpharm.2003.09.032. [PMID: 14698582] - Jorge Leguizamo, Mary Quinn, Chris H Takimoto, Michael D Liang, Abdel-Salam Attia Ismail, Janet Pang, William Dahut, Jean L Grem. A phase I study of 9-aminocamptothecin as a colloidal dispersion formulation given as a fortnightly 72-h infusion.
Cancer chemotherapy and pharmacology.
2003 Oct; 52(4):333-8. doi:
10.1007/s00280-003-0657-1. [PMID: 12819941] - L Perbellini, A Princivalle, M Caivano, R Montagnani. Biological monitoring of occupational exposure to N,N-dimethylacetamide with identification of a new metabolite.
Occupational and environmental medicine.
2003 Oct; 60(10):746-51. doi:
10.1136/oem.60.10.746. [PMID: 14504362] - Wilson Z Shou, Weng Naidong. Post-column infusion study of the 'dosing vehicle effect' in the liquid chromatography/tandem mass spectrometric analysis of discovery pharmacokinetic samples.
Rapid communications in mass spectrometry : RCM.
2003; 17(6):589-97. doi:
10.1002/rcm.951. [PMID: 12621622] - Madina R Gerasimov, Jean Logan, Richard A Ferrieri, Ryan D Muller, David Alexoff, Stephen L Dewey. Effect of vehicle on brain uptake of [11C]toluene.
Nuclear medicine and biology.
2002 Jul; 29(5):607-12. doi:
10.1016/s0969-8051(02)00315-3. [PMID: 12088732] - C Finlay, L A Malley, G L Kennedy. Absorption of dimethylacetamide (DMAC) following application of a polymer film to the skin of rabbits.
Applied occupational and environmental hygiene.
2001 Dec; 16(12):1103-5. doi:
10.1080/10473220127410. [PMID: 11783871] - T Nomiyama, K Omae, C Ishizuka, T Yamauchi, Y Kawasumi, K Yamada, H Endoh, H Sakurai. Dermal absorption of N,N-dimethylacetamide in human volunteers.
International archives of occupational and environmental health.
2000 Mar; 73(2):121-6. doi:
10.1007/s004200050017. [PMID: 10741510] - B S Andersson, T Madden, H T Tran, W W Hu, K G Blume, D S Chow, R E Champlin, W P Vaughan. Acute safety and pharmacokinetics of intravenous busulfan when used with oral busulfan and cyclophosphamide as pretransplantation conditioning therapy: a phase I study.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.
2000; 6(5A):548-54. doi:
10.1016/s1083-8791(00)70064-4. [PMID: 11071260] - T C Su, P H Lin, M J Chiu, T S Chu, M J Chang, J D Wang, T J Cheng. Dimethylacetamide, ethylenediamine, and diphenylmethane diisocyanate poisoning manifest as acute psychosis and pulmonary edema: treatment with hemoperfusion.
Journal of toxicology. Clinical toxicology.
2000; 38(4):429-33. doi:
10.1081/clt-100100953. [PMID: 10930060] - M Bosco, N Culeddu, R Toffanin, P Pollesello. Organic solvent systems for 31P nuclear magnetic resonance analysis of lecithin phospholipids: applications to two-dimensional gradient-enhanced 1H-detected heteronuclear multiple quantum coherence experiments.
Analytical biochemistry.
1997 Feb; 245(1):38-47. doi:
10.1006/abio.1996.9907. [PMID: 9025966] - H P Bhagwatwar, S Phadungpojna, D S Chow, B S Andersson. Formulation and stability of busulfan for intravenous administration in high-dose chemotherapy.
Cancer chemotherapy and pharmacology.
1996; 37(5):401-8. doi:
10.1007/s002800050404. [PMID: 8599861] - L A Malley, T W Slone, G T Makovec, G S Elliott, G L Kennedy. Chronic toxicity/oncogenicity of dimethylacetamide in rats and mice following inhalation exposure.
Fundamental and applied toxicology : official journal of the Society of Toxicology.
1995 Nov; 28(1):80-93. doi:
10.1006/faat.1995.1149. [PMID: 8566487] - G J Spies, R H Rhyne, R A Evans, K E Wetzel, D T Ragland, H G Turney, T L Leet, J L Oglesby. Monitoring acrylic fiber workers for liver toxicity and exposure to dimethylacetamide. 1. Assessing exposure to dimethylacetamide by air and biological monitoring.
Journal of occupational and environmental medicine.
1995 Sep; 37(9):1093-101. doi:
10.1097/00043764-199509000-00010. [PMID: 8528717] - S G Hundley, P H Lieder, R Valentine, K T McCooey, G L Kennedy. Dimethylacetamide pharmacokinetics following inhalation exposures to rats and mice.
Toxicology letters.
1994 Sep; 73(3):213-25. doi:
10.1016/0378-4274(94)90061-2. [PMID: 8091430] - L A Kinney, B A Burgess, E F Stula, G L Kennedy. Inhalation studies in rats exposed to dimethylacetamide (DMAc) from 3 to 12 hours per day.
Drug and chemical toxicology.
1993; 16(2):175-94. doi:
10.3109/01480549309031995. [PMID: 8486098] - G L Kennedy, J W Pruett. Biologic monitoring for dimethylacetamide: measurement for 4 consecutive weeks in a workplace.
Journal of occupational medicine. : official publication of the Industrial Medical Association.
1989 Jan; 31(1):47-50. doi:
NULL. [PMID: 2738751] - G M Wang, L D Kier, G W Pounds. Male fertility study on N,N-dimethylacetamide administered by the inhalation route to Sprague-Dawley rats.
Journal of toxicology and environmental health.
1989; 27(3):297-305. doi:
10.1080/15287398909531301. [PMID: 2754756] - P J Borm, L de Jong, A Vliegen. Environmental and biological monitoring of workers occupationally exposed to dimethylacetamide.
Journal of occupational medicine. : official publication of the Industrial Medical Association.
1987 Nov; 29(11):898-903. doi:
NULL. [PMID: 3681500] - G L Kennedy. Biological effects of acetamide, formamide, and their monomethyl and dimethyl derivatives.
Critical reviews in toxicology.
1986; 17(2):129-82. doi:
10.3109/10408448609023768. [PMID: 3530639] - F J Dutko, M B Oldstone. Cytomegalovirus causes a latent infection in undifferentiated cells and is activated by induction of cell differentiation.
The Journal of experimental medicine.
1981 Nov; 154(5):1636-51. doi:
10.1084/jem.154.5.1636. [PMID: 6271894]