5-dodecenoate (12:1n7) (BioDeep_00000018628)

 

Secondary id: BioDeep_00000229639, BioDeep_00000405294, BioDeep_00000593592, BioDeep_00001871854

human metabolite PANOMIX_OTCML-2023 Endogenous


代谢物信息卡片


5-Dodecenoic acid, (e)-isomer

化学式: C12H22O2 (198.1619712)
中文名称: 顺-5-十二碳烯酸, 十二烯酸, 5Z-十二碳烯酸
谱图信息: 最多检出来源 Viridiplantae(plant) 0.24%

Reviewed

Last reviewed on 2024-09-13.

Cite this Page

5-dodecenoate (12:1n7). BioDeep Database v3. PANOMIX ltd, a top metabolomics service provider from China. https://query.biodeep.cn/s/5-dodecenoate_(12:1n7) (retrieved 2024-11-08) (BioDeep RN: BioDeep_00000018628). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

分子结构信息

SMILES: CCCCCC/C=C\CCCC(O)=O
InChI: InChI=1S/C12H22O2/c1-2-3-4-5-6-7-8-9-10-11-12(13)14/h7-8H,2-6,9-11H2,1H3,(H,13,14)

描述信息

5Z-Dodecenoic acid, also known as 5-dodecenoic acid or 5-dodecenoate, is a monounsaturated fatty acid that has a C12 chain as a backbone and a cis double bond at the C5 position. 5-Dodecenoic acid is a member of the class of compounds known as medium-chain fatty acids. Medium-chain fatty acids are fatty acids with an aliphatic tail that contains between 4 and 12 carbon atoms. Thus, 5-dodecenoic acid is considered to be a fatty acid lipid molecule. 5-Dodecenoic acid is practically insoluble (in water) and a weakly acidic compound (based on its pKa). Within the cell, 5-dodecenoic acid is primarily located in the cytoplasm and in the membrane (predicted from logP). It can also be found in the extracellular space. An increase of 5-dodecenoic acid in plasma is associated with acyl-CoA dehydrogenase deficiency disorders (PMID: 7586519). 5-Dodecenoic acid is an intermediate of unsaturated fatty acid oxidation.
5-Dodecenoic acid is an intermediate of unsaturated fatty acid oxidation. An increase of 5-dodecenoic acid in plasma is associated with acyl-CoA dehydrogenase deficiency disorders. (PMID 7586519) [HMDB]
cis-5-Dodecenoic acid is an endogenous metabolite with inhibitory activities against COX-I and COX-II[1].

同义名列表

17 个代谢物同义名

5-Dodecenoic acid, (e)-isomer; (5Z)-dodec-5-enoic acid; (Z)-Dodec-5-enoic acid; (Z)-5-Dodecenoic acid; cis-5-Dodecanoic acid; cis-5-dodecenoic acid; (Z)-Dodec-5-enoate; 5Z-dodecenoic acid; cis-5-Dodecanoate; cis-5-Dodecenoate; 5-Dodecenoic acid; (Z)-5-Dodecenoate; 5Z-Dodecenoate; 5-Dodecenoate; FA(12:1(5Z)); Lauroleinate; 5Z-Dodecenoic acid



数据库引用编号

10 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

2 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Yunbao Liu, Muraleedharan G Nair. An efficient and economical MTT assay for determining the antioxidant activity of plant natural product extracts and pure compounds. Journal of natural products. 2010 Jul; 73(7):1193-5. doi: 10.1021/np1000945. [PMID: 20565070]
  • W Onkenhout, V Venizelos, H R Scholte, J B De Klerk, B J Poorthuis. Intermediates of unsaturated fatty acid oxidation are incorporated in triglycerides but not in phospholipids in tissues from patients with mitochondrial beta-oxidation defects. Journal of inherited metabolic disease. 2001 Jun; 24(3):337-44. doi: 10.1023/a:1010592232317. [PMID: 11486898]