Minoxidil (BioDeep_00000018613)

human metabolite blood metabolite Chemicals and Drugs

代谢物信息卡片

2,6-diamino-4-(piperidin-1-yl)pyrimidin-1-ium-1-olate

化学式: C9H15N5O (209.127654)
中文名称: 米诺地尔
谱图信息: 最多检出来源 Homo sapiens(blood) 95.83%

分子结构信息

SMILES: C1CCN(CC1)C2=NC(=N)N(C(=C2)N)O
InChI: InChI=1S/C9H15N5O/c10-7-6-8(12-9(11)14(7)15)13-4-2-1-3-5-13/h6,11,15H,1-5,10H2

描述信息

Minoxidil is only found in individuals that have used or taken this drug. It is a potent direct-acting peripheral vasodilator (vasodilator agents) that reduces peripheral resistance and produces a fall in blood pressure. (From Martindale, The Extra Pharmacopoeia, 30th ed, p371)Minoxidil is thought to promote the survival of human dermal papillary cells (DPCs) or hair cells by activating both extracellular signal-regulated kinase (ERK) and Akt and by preventing cell death by increasing the ratio of BCl^-2/Bax. Minoxidil may stimulate the growth of human hairs by prolonging anagen through these proliferative and anti-apoptotic effects on DPCs. Minoxidil, when used as a vasodilator, acts by opening adenosine triphosphate-sensitive potassium channels in vascular smooth muscle cells. This vasodilation may also improve the viability of hair cells or hair follicles.
C - Cardiovascular system > C02 - Antihypertensives > C02D - Arteriolar smooth muscle, agents acting on > C02DC - Pyrimidine derivatives
C78274 - Agent Affecting Cardiovascular System > C270 - Antihypertensive Agent
C78274 - Agent Affecting Cardiovascular System > C29707 - Vasodilating Agent
D002317 - Cardiovascular Agents > D000959 - Antihypertensive Agents
D002317 - Cardiovascular Agents > D014665 - Vasodilator Agents
D - Dermatologicals

同义名列表

14 个代谢物同义名

2,6-diamino-4-(piperidin-1-yl)pyrimidin-1-ium-1-olate; Minoxidilum; Normoxidil; Tricoxidil; Minoxidil; Minoximen; Apo-gain; AK-49175; Loniten; Rogaine; Lonolox; Regaine; Alostil; Riup

数据库引用编号

14 个数据库交叉引用编号

ChEBI: CHEBI:92128
ChEBI: CHEBI:6942
PubChem: 135743713
PubChem: 4201
HMDB: HMDB0014494
DrugBank: DB00350
ChEMBL: CHEMBL1372483
ChEMBL: CHEMBL609587
ChEMBL: CHEMBL802
Wikipedia: Minoxidil
MeSH: Minoxidil
chemspider: 10438564
CAS: 38304-91-5
PMhub: MS000009616

分类词条

Dialkylarylamines

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

9606 - Homo sapiens: -

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

文献列表

Zehui He, Yongtai Zhang, Zhenda Liu, Teng Guo, Xinyi Ai, Yuanzhi He, Xiaolin Hou, Nianping Feng. Synergistic treatment of androgenetic alopecia with follicular co-delivery of minoxidil and cedrol in metal-organic frameworks stabilized by covalently cross-linked cyclodextrins. International journal of pharmaceutics. 2024 Apr; 654(?):123948. doi: 10.1016/j.ijpharm.2024.123948. [PMID: 38417724]
Lifang Hu, YeQin Dai, Hongyan Zhang, Yi Wu, Tao Wang, Xiuzu Song. Efficacy and safety of botulinum toxin A in the treatment of female pattern hair loss. Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI). 2024 Apr; 30(4):e13696. doi: 10.1111/srt.13696. [PMID: 38602262]
Tyler E Johnson, Meghan E Fick, Jenica L Haraschak, Mara E Vernier, Saki Kadotani. Successful management of minoxidil 5\% toxicosis in 2 cats from the same household. Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001). 2023 Jul; 33(4):454-459. doi: 10.1111/vec.13296. [PMID: 37222073]
Marzough Aziz Albalawi, Ahmed M Hafez, Seham S Elhawary, Nada K Sedky, Omnia F Hassan, Rofanda M Bakeer, Soha Abd El Hadi, Ahmed H El-Desoky, Sebaey Mahgoub, Fatma A Mokhtar. The medicinal activity of lyophilized aqueous seed extract of Lepidium sativum L. in an androgenic alopecia model. Scientific reports. 2023 May; 13(1):7676. doi: 10.1038/s41598-023-33988-1. [PMID: 37169776]
Jianfeng Zhang, Peng Lin, Haiyue Lin, Cong Ma, Yi Hu, Yingdong Wang, Yu Zhang. Laser and light therapy combined with topical minoxidil for alopecia areata: a systematic review and meta-analysis of randomized controlled trials. Lasers in medical science. 2023 Feb; 38(1):74. doi: 10.1007/s10103-023-03734-0. [PMID: 36800063]
Khushbakht Saleem, Bazla Siddiqui, Asim Ur Rehman, Malik Mumtaz Taqi, Naveed Ahmed. Exploiting Recent Trends in the Treatment of Androgenic Alopecia through Topical Nanocarriers of Minoxidil. AAPS PharmSciTech. 2022 Nov; 23(8):292. doi: 10.1208/s12249-022-02444-0. [PMID: 36319878]
Chi Liu, Hongwei Zhao, Ying Zhang, Wei Wu. Clinical observation of basic fibroblast growth factor (bFGF) combined with minoxidil in the treatment of male androgenetic alopecia. Journal of cosmetic dermatology. 2022 Sep; 21(9):4053-4059. doi: 10.1111/jocd.14735. [PMID: 35037386]
Mohammed Elmowafy, Khaled Shalaby, Nabil K Alruwaili, Mohammed H Elkomy, Ameeduzzafar Zafar, Ghareb M Soliman, Ayman Salama, Elsaied H Barakat. EthoLeciplex: a new tool for effective cutaneous delivery of minoxidil. Drug development and industrial pharmacy. 2022 Sep; 48(9):457-469. doi: 10.1080/03639045.2022.2124261. [PMID: 36093810]
Jinjin Dou, Zhiming Zhang, Xianrong Xu, Xiwu Zhang. Exploring the effects of Chinese herbal ingredients on the signaling pathway of alopecia and the screening of effective Chinese herbal compounds. Journal of ethnopharmacology. 2022 Aug; 294(?):115320. doi: 10.1016/j.jep.2022.115320. [PMID: 35483562]
Henny Kasmawati, Resmi Mustarichie, Eli Halimah, Ruslin Ruslin, Arfan Arfan, Nurramadhani A Sida. Unrevealing the Potential of Sansevieria trifasciata Prain Fraction for the Treatment of Androgenetic Alopecia by Inhibiting Androgen Receptors Based on LC-MS/MS Analysis, and In-Silico Studies. Molecules (Basel, Switzerland). 2022 Jul; 27(14):. doi: 10.3390/molecules27144358. [PMID: 35889232]
Doris Day, Madison McCarthy, Iva Talaber. Non-ablative Er:YAG laser is an effective tool in the treatment arsenal of androgenetic alopecia. Journal of cosmetic dermatology. 2022 May; 21(5):2056-2063. doi: 10.1111/jocd.14370. [PMID: 34435735]
Aditya K Gupta, Mesbah Talukder. Topical finasteride for male and female pattern hair loss: Is it a safe and effective alternative?. Journal of cosmetic dermatology. 2022 May; 21(5):1841-1848. doi: 10.1111/jocd.14895. [PMID: 35238144]
Sara Abdel Gawad Elsebay, Hoda Fouad Nada, Nancy Sultan Saad Sultan, Dalia Alaa El-Din Aly El-Waseef. Comparative histological and immunohistochemical study on the effect of platelet rich plasma/minoxidil, alone or in combination, on hair growth in a rat model of androgenic alopecia. Tissue & cell. 2022 Apr; 75(?):101726. doi: 10.1016/j.tice.2021.101726. [PMID: 35030343]
Paula M Oliveira, Thuany Alencar-Silva, Felipe Q Pires, Marcilio Cunha-Filho, Tais Gratieri, Juliana Lott Carvalho, Guilherme M Gelfuso. Nanostructured lipid carriers loaded with an association of minoxidil and latanoprost for targeted topical therapy of alopecia. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 2022 Mar; 172(?):78-88. doi: 10.1016/j.ejpb.2022.02.003. [PMID: 35143972]
P Poorna Basuri, R Vijayakumar, C N Nalini. Estimation of minoxidil in human plasma using UHPLC-MS/MS and its application in pharmacokinetic study. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2022 Mar; 1192(?):123104. doi: 10.1016/j.jchromb.2022.123104. [PMID: 35168153]
Aditya K Gupta, Mary A Bamimore, Kelly A Foley. Efficacy of non-surgical treatments for androgenetic alopecia in men and women: a systematic review with network meta-analyses, and an assessment of evidence quality. The Journal of dermatological treatment. 2022 Feb; 33(1):62-72. doi: 10.1080/09546634.2020.1749547. [PMID: 32250713]
Aditya K Gupta, Emma M Quinlan, Maanasa Venkataraman, Mary A Bamimore. Microneedling for Hair Loss. Journal of cosmetic dermatology. 2022 Jan; 21(1):108-117. doi: 10.1111/jocd.14525. [PMID: 34714971]
Christina M Ring, Robert Finney, Marc Avram. Lasers, lights, and compounds for hair loss in aesthetics. Clinics in dermatology. 2022 Jan; 40(1):64-75. doi: 10.1016/j.clindermatol.2021.08.013. [PMID: 35190067]
Ramesh Venkatesh, Arpitha Pereira, Nikitha Gurram Reddy, Naresh Kumar Yadav. Retinal artery occlusion as a probable idiosyncratic reaction to topical minoxidil: a case report. Journal of medical case reports. 2021 Oct; 15(1):493. doi: 10.1186/s13256-021-03114-8. [PMID: 34620244]
Abhijeet Kumar Jha, Md Zeeshan, Anupama Singh, Prasoon Kumar Roy. Platelet-rich plasma with low dose oral minoxidil (1.25mg versus 2.5mg) along with trichoscopic pre- and post-treatment evaluation. Journal of cosmetic dermatology. 2021 Oct; 20(10):3220-3226. doi: 10.1111/jocd.14049. [PMID: 33682223]
Ibrahim M Ibrahim, Mohamed S Hasan, Khaled I Elsabaa, Mohamed L Elsaie. Pumpkin seed oil vs. minoxidil 5\% topical foam for the treatment of female pattern hair loss: A randomized comparative trial. Journal of cosmetic dermatology. 2021 Sep; 20(9):2867-2873. doi: 10.1111/jocd.13976. [PMID: 33544448]
Arpar Ngampanya, Udomsak Udomnilobol, Pakawadee Sermsappasuk, Natapol Pornputtapong, Boonsri Ongpipattanakul, Nikunjkumar Patel, Suree Jianmongkol, Thomayant Prueksaritanont. Development and Qualification of a Physiologically Based Pharmacokinetic Model of Finasteride and Minoxidil Following Scalp Application. Journal of pharmaceutical sciences. 2021 05; 110(5):2301-2310. doi: 10.1016/j.xphs.2021.02.016. [PMID: 33609522]
Soo Hee Lee, Seong-Ho Ok, Dawon Kang, Hyun-Jin Kim, Seung Hyun Ahn, Sung Il Bae, Ji-Yoon Kim, Eun-Jin Kim, Sunmin Kim, Yeran Hwag, Ju-Tae Sohn. Nitric oxide-dependent vasodilation induced by minoxidil in isolated rat aorta. General physiology and biophysics. 2021 May; 40(3):197-206. doi: 10.4149/gpb_2021012. [PMID: 34100376]
A Sterkens, J Lambert, A Bervoets. Alopecia areata: a review on diagnosis, immunological etiopathogenesis and treatment options. Clinical and experimental medicine. 2021 May; 21(2):215-230. doi: 10.1007/s10238-020-00673-w. [PMID: 33386567]
Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome. Cell reports. 2021 04; 35(4):109040. doi: 10.1016/j.celrep.2021.109040. [PMID: 33910017]
Santo Raffaele Mercuri, Giovanni Paolino, Matteo Riccardo Di Nicola, Laura Vollono. Investigating the Safety and Efficacy of Platelet-Rich Plasma (PRP) Treatment for Female Androgenetic Alopecia: Review of the Literature. Medicina (Kaunas, Lithuania). 2021 Mar; 57(4):. doi: 10.3390/medicina57040311. [PMID: 33806169]
Ginny Oong Chien Yin, Joyce Lee Siong-See, Etienne C E Wang. Telogen Effluvium - a review of the science and current obstacles. Journal of dermatological science. 2021 Mar; 101(3):156-163. doi: 10.1016/j.jdermsci.2021.01.007. [PMID: 33541773]
Masoumeh Roohaninasab, Azadeh Goodarzi, Mohammadreza Ghassemi, Afsaneh Sadeghzadeh-Bazargan, Elham Behrangi, Niloufar Najar Nobari. Systematic review of platelet-rich plasma in treating alopecia: Focusing on efficacy, safety, and therapeutic durability. Dermatologic therapy. 2021 03; 34(2):e14768. doi: 10.1111/dth.14768. [PMID: 33421285]
D S Shah, D K Jha, P D Amin. Development, validation, and application of an RP-HPLC method for concurrent quantification of Minoxidil and Finasteride in a topical solution for hair regrowth. Annales pharmaceutiques francaises. 2021 Mar; 79(2):194-206. doi: 10.1016/j.pharma.2020.10.003. [PMID: 33091398]
T Moreau, C Castronovo, J F Kaux, A F Nikkels, P Paquet. [A new treatment for androgenetic alopecia : platelet-rich plasma injections]. Revue medicale de Liege. 2021 Feb; 76(2):117-121. doi: NULL. [PMID: 33543858]
Brittney R Garner, Amanda J Stolarz, Daniel Stuckey, Mustafa Sarimollaoglu, Yunmeng Liu, Philip T Palade, Nancy J Rusch, Shengyu Mu. KATP Channel Openers Inhibit Lymphatic Contractions and Lymph Flow as a Possible Mechanism of Peripheral Edema. The Journal of pharmacology and experimental therapeutics. 2021 01; 376(1):40-50. doi: 10.1124/jpet.120.000121. [PMID: 33100270]
Elena E Pakhomova, Irina O Smirnova. Comparative Evaluation of the Clinical Efficacy of PRP-Therapy, Minoxidil, and Their Combination with Immunohistochemical Study of the Dynamics of Cell Proliferation in the Treatment of Men with Androgenetic Alopecia. International journal of molecular sciences. 2020 Sep; 21(18):. doi: 10.3390/ijms21186516. [PMID: 32899959]
Basile Chrétien, Marion Sassier, Joachim Alexandre, Véronique Lelong-Boulouard, Charles Dolladille, Sophie Fedrizzi. Direct acting oral anticoagulants and alopecia: to go further with data mining in pharmacovigilance databases. European journal of clinical pharmacology. 2020 Aug; 76(8):1197-1198. doi: 10.1007/s00228-020-02891-3. [PMID: 32435997]
Hassan Galadari, Swathi Shivakumar, Torello Lotti, Uwe Wollina, Andy Goren, Ghasem Rahmatpour Rokni, Stephan Grabbe, Mohamad Goldust. Low-level laser therapy and narrative review of other treatment modalities in androgenetic alopecia. Lasers in medical science. 2020 Aug; 35(6):1239-1244. doi: 10.1007/s10103-020-02994-4. [PMID: 32162134]
Mahmoud Makki, Abdel-Khalek Hassan Younes, Islam Salah. Evaluation of the effect of autologous platelet-rich plasma on androgenic alopecia. Journal of cosmetic and laser therapy : official publication of the European Society for Laser Dermatology. 2020 Jul; 22(4-5):190-194. doi: 10.1080/14764172.2020.1827150. [PMID: 33012215]
Fatima Maqoud, Nicola Zizzo, Antonietta Mele, Nunzio Denora, Giuseppe Passantino, Rosa Scala, Annalisa Cutrignelli, Antonella Tinelli, Valentino Laquintana, Flavia la Forgia, Sergio Fontana, Massimo Franco, Angela Assunta Lopedota, Domenico Tricarico. The hydroxypropyl-β-cyclodextrin-minoxidil inclusion complex improves the cardiovascular and proliferative adverse effects of minoxidil in male rats: Implications in the treatment of alopecia. Pharmacology research & perspectives. 2020 06; 8(3):e00585. doi: 10.1002/prp2.585. [PMID: 32378360]
Alison J Bruce, Thais P Pincelli, Michael G Heckman, Cheryl M Desmond, Jennifer R Arthurs, Nancy N Diehl, Erika J Douglass, Charles J Bruce, Shane A Shapiro. A Randomized, Controlled Pilot Trial Comparing Platelet-Rich Plasma to Topical Minoxidil Foam for Treatment of Androgenic Alopecia in Women. Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]. 2020 06; 46(6):826-832. doi: 10.1097/dss.0000000000002168. [PMID: 31574029]
Pietro Gentile, Simone Garcovich. Systematic Review of Platelet-Rich Plasma Use in Androgenetic Alopecia Compared with Minoxidil®, Finasteride®, and Adult Stem Cell-Based Therapy. International journal of molecular sciences. 2020 Apr; 21(8):. doi: 10.3390/ijms21082702. [PMID: 32295047]
Katherine York, Nekma Meah, Bevin Bhoyrul, Rodney Sinclair. A review of the treatment of male pattern hair loss. Expert opinion on pharmacotherapy. 2020 04; 21(5):603-612. doi: 10.1080/14656566.2020.1721463. [PMID: 32066284]
Satyendra Kumar Singh, Vijay Kumar, Tulika Rai. Comparison of efficacy of platelet-rich plasma therapy with or without topical 5\% minoxidil in male-type baldness: A randomized, double-blind placebo control trial. Indian journal of dermatology, venereology and leprology. 2020 Mar; 86(2):150-157. doi: 10.4103/ijdvl.ijdvl_589_18. [PMID: 31823902]
Maria Mayfinna Gozali, Yuli Kurniawati, Sarah Diba Zulkarnain. Microneedling and Platelet-Rich Plasma versus Microneedling and 5\% Topical Minoxidil Therapy in Male Pattern Hair Loss. Skinmed. 2020; 18(3):176-178. doi: NULL. [PMID: 32790616]
Keun-Hyeun Lee, Dabin Choi, Seung-Il Jeong, Sang-Jun Kim, Chang Hyun Lee, Hyung-Sik Seo, Han-Sol Jeong. Eclipta prostrata promotes the induction of anagen, sustains the anagen phase through regulation of FGF-7 and FGF-5. Pharmaceutical biology. 2019 Dec; 57(1):105-111. doi: 10.1080/13880209.2018.1561729. [PMID: 30757935]
Tobie D Lee, Olivia W Lee, Kyle R Brimacombe, Lu Chen, Rajarshi Guha, Sabrina Lusvarghi, Bethilehem G Tebase, Carleen Klumpp-Thomas, Robert W Robey, Suresh V Ambudkar, Min Shen, Michael M Gottesman, Matthew D Hall. A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. Molecular pharmacology. 2019 11; 96(5):629-640. doi: 10.1124/mol.119.115964. [PMID: 31515284]
Tatiele Katzer, Ademir Leite Junior, Ruy Beck, Cristiane da Silva. Physiopathology and current treatments of androgenetic alopecia: Going beyond androgens and anti-androgens. Dermatologic therapy. 2019 09; 32(5):e13059. doi: 10.1111/dth.13059. [PMID: 31400254]
Enrico Carmina, Ricardo Azziz, Wilma Bergfeld, Héctor F Escobar-Morreale, Walter Futterweit, Heather Huddleston, Rogerio Lobo, Elise Olsen. Female Pattern Hair Loss and Androgen Excess: A Report From the Multidisciplinary Androgen Excess and PCOS Committee. The Journal of clinical endocrinology and metabolism. 2019 07; 104(7):2875-2891. doi: 10.1210/jc.2018-02548. [PMID: 30785992]
Abhijeet Kumar Jha. Platelet-rich plasma as an adjunctive treatment in lichen planopilaris. Journal of the American Academy of Dermatology. 2019 05; 80(5):e109-e110. doi: 10.1016/j.jaad.2018.09.013. [PMID: 30244063]
Eduardo Anitua, Ander Pino, Pedro Jaén, Mª Rogelia Navarro. Platelet rich plasma for the management of hair loss: Better alone or in combination?. Journal of cosmetic dermatology. 2019 Apr; 18(2):483-486. doi: 10.1111/jocd.12683. [PMID: 29904992]
Philip R Cohen. Laser-assisted drug delivery for the treatment of androgenetic alopecia: ablative laser fractional photothermolysis to enhance cutaneous topical delivery of platelet-rich plasma - with or without concurrent bimatoprost and/or minoxidil. Dermatology online journal. 2019 Feb; 25(2):. doi: NULL. [PMID: 30865404]
Poonkiat Suchonwanit, Wimolsiri Iamsumang, Salinee Rojhirunsakool. Efficacy of Topical Combination of 0.25\% Finasteride and 3\% Minoxidil Versus 3\% Minoxidil Solution in Female Pattern Hair Loss: A Randomized, Double-Blind, Controlled Study. American journal of clinical dermatology. 2019 Feb; 20(1):147-153. doi: 10.1007/s40257-018-0387-0. [PMID: 30206824]
Kristin Bater, Evan Rieder. Over-the-Counter Hair Loss Treatments: Help or Hype?. Journal of drugs in dermatology : JDD. 2018 12; 17(12):1317-1321. doi: ". [PMID: 30586264]
A K Gupta, R R Mays, M S Dotzert, S G Versteeg, N H Shear, V Piguet. Efficacy of non-surgical treatments for androgenetic alopecia: a systematic review and network meta-analysis. Journal of the European Academy of Dermatology and Venereology : JEADV. 2018 Dec; 32(12):2112-2125. doi: 10.1111/jdv.15081. [PMID: 29797431]
P Suchonwanit, P Srisuwanwattana, N Chalermroj, S Khunkhet. A randomized, double-blind controlled study of the efficacy and safety of topical solution of 0.25\% finasteride admixed with 3\% minoxidil vs. 3\% minoxidil solution in the treatment of male androgenetic alopecia. Journal of the European Academy of Dermatology and Venereology : JEADV. 2018 Dec; 32(12):2257-2263. doi: 10.1111/jdv.15171. [PMID: 29972712]
Songjun Shao, Xiangning Zhang, Lingdi Duan, Haiyan Fang, Shanshan Rao, Weijia Liu, Bing Guo, Xiangyan Zhang. Lysyl Hydroxylase Inhibition by Minoxidil Blocks Collagen Deposition and Prevents Pulmonary Fibrosis via TGF-β₁/Smad3 Signaling Pathway. Medical science monitor : international medical journal of experimental and clinical research. 2018 Nov; 24(?):8592-8601. doi: 10.12659/msm.910761. [PMID: 30481795]
A Gomez-Zubiaur, D Saceda-Corralo, M D Velez-Velazquez, S Vano-Galvan. Title Not Available. Dermatology online journal. 2018 Jul; 24(7):. doi: NULL. [PMID: 30261562]
Dorottya Nagy-Szakal, Dinesh K Barupal, Bohyun Lee, Xiaoyu Che, Brent L Williams, Ellie J R Kahn, Joy E Ukaigwe, Lucinda Bateman, Nancy G Klimas, Anthony L Komaroff, Susan Levine, Jose G Montoya, Daniel L Peterson, Bruce Levin, Mady Hornig, Oliver Fiehn, W Ian Lipkin. Insights into myalgic encephalomyelitis/chronic fatigue syndrome phenotypes through comprehensive metabolomics. Scientific reports. 2018 07; 8(1):10056. doi: 10.1038/s41598-018-28477-9. [PMID: 29968805]
Jukkarin Srivilai, Neti Waranuch, Anothai Tangsumranjit, Nantaka Khorana, Kornkanok Ingkaninan. Germacrone and sesquiterpene-enriched extracts from Curcuma aeruginosa Roxb. increase skin penetration of minoxidil, a hair growth promoter. Drug delivery and translational research. 2018 02; 8(1):140-149. doi: 10.1007/s13346-017-0447-7. [PMID: 29159692]
Tyler J M Jordan, Page E Yaxley, Christine A Culler, Anusha Balakrishnan. Successful management of minoxidil toxicosis in a dog. Journal of the American Veterinary Medical Association. 2018 Jan; 252(2):222-226. doi: 10.2460/javma.252.2.222. [PMID: 29319439]
V Kanti, A Messenger, G Dobos, P Reygagne, A Finner, A Blumeyer, M Trakatelli, A Tosti, V Del Marmol, B M Piraccini, A Nast, U Blume-Peytavi. Evidence-based (S3) guideline for the treatment of androgenetic alopecia in women and in men - short version. Journal of the European Academy of Dermatology and Venereology : JEADV. 2018 Jan; 32(1):11-22. doi: 10.1111/jdv.14624. [PMID: 29178529]
Rubina Alves, Ramon Grimalt. Platelet-Rich Plasma in Combination With 5\% Minoxidil Topical Solution and 1 mg Oral Finasteride for the Treatment of Androgenetic Alopecia: A Randomized Placebo-Controlled, Double-Blind, Half-Head Study. Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]. 2018 Jan; 44(1):126-130. doi: 10.1097/dss.0000000000001198. [PMID: 28562433]
Yonghee Lee, Su Na Kim, Yong Deog Hong, Byung Cheol Park, Yongjoo Na. Panax ginseng extract antagonizes the effect of DKK‑1-induced catagen-like changes of hair follicles. International journal of molecular medicine. 2017 Oct; 40(4):1194-1200. doi: 10.3892/ijmm.2017.3107. [PMID: 28849028]
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