7-Oxononane-1,1,9-tricarbaldehyde (BioDeep_00000185422)
human metabolite blood metabolite
代谢物信息卡片
3-oxononane-1,9,9-tricarbaldehyde
化学式: C12H18O4 (226.1205028)
中文名称:
谱图信息:
最多检出来源 Bos taurus(blood) 1.27%
分子结构信息
SMILES: C(CCC(C=O)C=O)CCC(=O)CCC=O
InChI: InChI=1S/C12H18O4/c13-8-4-7-12(16)6-3-1-2-5-11(9-14)10-15/h8-11H,1-7H2
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Fang Cai, Yves Marc Dupertuis, Claude Pichard. Role of polyunsaturated fatty acids and lipid peroxidation on colorectal cancer risk and treatments.
Current opinion in clinical nutrition and metabolic care.
2012 Mar; 15(2):99-106. doi:
10.1097/mco.0b013e32834feab4. [PMID: 22234166] - Mohamed E Shaker, Gamal E Shiha, Tarek M Ibrahim. Comparison of early treatment with low doses of nilotinib, imatinib and a clinically relevant dose of silymarin in thioacetamide-induced liver fibrosis.
European journal of pharmacology.
2011 Nov; 670(2-3):593-600. doi:
10.1016/j.ejphar.2011.08.041. [PMID: 21925495] - Xiaodong Wang, Defeng Wu, Lili Yang, Arthur I Cederbaum. Hepatotoxicity mediated by pyrazole (cytochrome P450 2E1) plus tumor necrosis factor alpha treatment occurs in c-Jun N-terminal kinase 2-/- but not in c-Jun N-terminal kinase 1-/- mice.
Hepatology (Baltimore, Md.).
2011 Nov; 54(5):1753-66. doi:
10.1002/hep.24540. [PMID: 21748763] - Z Tatarková, S Kuka, P Račay, J Lehotský, D Dobrota, D Mištuna, P Kaplán. Effects of aging on activities of mitochondrial electron transport chain complexes and oxidative damage in rat heart.
Physiological research.
2011; 60(2):281-9. doi:
10.33549/physiolres.932019. [PMID: 21114360] - Venkatramanujam Srinivasan, Charanjit Kaur, Seithikurippu Pandi-Perumal, Gregory M Brown, Daniel P Cardinali. Melatonin and its agonist ramelteon in Alzheimer's disease: possible therapeutic value.
International journal of Alzheimer's disease.
2010 Dec; 2011(?):741974. doi:
10.4061/2011/741974. [PMID: 21197086] - Nicolle Breusing, Tilman Grune, Luka Andrisic, Mustafa Atalay, Grzegorz Bartosz, Fiorella Biasi, Suzana Borovic, Laura Bravo, Isidre Casals, Rosario Casillas, Anca Dinischiotu, Joanna Drzewinska, Heidemarie Faber, Norsyahida Mohd Fauzi, Agnieszka Gajewska, Juan Gambini, Daniela Gradinaru, Tarja Kokkola, Antonin Lojek, Wojciech Luczaj, Denisa Margina, Cinzia Mascia, Raquel Mateos, Andreas Meinitzer, María Teresa Mitjavila, Lidija Mrakovcic, Maria Cristina Munteanu, Martina Podborska, Giuseppe Poli, Paulina Sicinska, Elzbieta Skrzydlewska, Jose Vina, Ingrid Wiswedel, Neven Zarkovic, Sieglinde Zelzer, Corinne M Spickett. An inter-laboratory validation of methods of lipid peroxidation measurement in UVA-treated human plasma samples.
Free radical research.
2010 Oct; 44(10):1203-15. doi:
10.3109/10715762.2010.499907. [PMID: 20836662] - Simona G Codreanu, Bing Zhang, Scott M Sobecki, Dean D Billheimer, Daniel C Liebler. Global analysis of protein damage by the lipid electrophile 4-hydroxy-2-nonenal.
Molecular & cellular proteomics : MCP.
2009 Apr; 8(4):670-80. doi:
10.1074/mcp.m800070-mcp200. [PMID: 19054759] - Sharda P Singh, Maciej Niemczyk, Ludwika Zimniak, Piotr Zimniak. Fat accumulation in Caenorhabditis elegans triggered by the electrophilic lipid peroxidation product 4-hydroxynonenal (4-HNE).
Aging.
2008 Dec; 1(1):68-80. doi:
10.18632/aging.100005. [PMID: 20157589] - Laurie A VanderVeen, Thomas M Harris, Linda Jen-Jacobson, Lawrence J Marnett. Formation of DNA-protein cross-links between gamma-hydroxypropanodeoxyguanosine and EcoRI.
Chemical research in toxicology.
2008 Sep; 21(9):1733-8. doi:
10.1021/tx800092g. [PMID: 18690724] - Rao Muralikrishna Adibhatla, J F Hatcher. Phospholipase A2, reactive oxygen species, and lipid peroxidation in cerebral ischemia.
Free radical biology & medicine.
2006 Feb; 40(3):376-87. doi:
10.1016/j.freeradbiomed.2005.08.044. [PMID: 16443152] - Sergio Neri, Salvatore S Signorelli, Benedetto Torrisi, Davide Pulvirenti, Barbara Mauceri, Giuseppe Abate, Luca Ignaccolo, Fabio Bordonaro, Danila Cilio, Stefano Calvagno, Carmelo Leotta. Effects of antioxidant supplementation on postprandial oxidative stress and endothelial dysfunction: a single-blind, 15-day clinical trial in patients with untreated type 2 diabetes, subjects with impaired glucose tolerance, and healthy controls.
Clinical therapeutics.
2005 Nov; 27(11):1764-73. doi:
10.1016/j.clinthera.2005.11.006. [PMID: 16368447] - Supratim Ray, Chandana Sengupta, Kunal Roy. Evaluation of ascorbic acid as suppressor of cyclophosphamide induced lipid peroxidation using common laboratory markers.
Acta poloniae pharmaceutica.
2005 Mar; 62(2):145-52. doi:
". [PMID: 16161357] - Ingrid Wiswedel, Daniela Hirsch, Francesco Carluccio, Hannelore Hampl, Werner Siems. F2-isoprostanes as biomarkers of lipid peroxidation in patients with chronic renal failure.
BioFactors (Oxford, England).
2005; 24(1-4):201-8. doi:
10.1002/biof.5520240124. [PMID: 16403981] - M Valko, H Morris, M T D Cronin. Metals, toxicity and oxidative stress.
Current medicinal chemistry.
2005; 12(10):1161-208. doi:
10.2174/0929867053764635. [PMID: 15892631] - Irfan Rahman, Saibal K Biswas. Non-invasive biomarkers of oxidative stress: reproducibility and methodological issues.
Redox report : communications in free radical research.
2004; 9(3):125-43. doi:
10.1179/135100004225005219. [PMID: 15327743] - Tamara R Knight, Marc W Fariss, Anwar Farhood, Hartmut Jaeschke. Role of lipid peroxidation as a mechanism of liver injury after acetaminophen overdose in mice.
Toxicological sciences : an official journal of the Society of Toxicology.
2003 Nov; 76(1):229-36. doi:
10.1093/toxsci/kfg220. [PMID: 12944590] - M Przekwas, S Małgorzewicz, Z Zdrojewski, A Debska-Slizień, W Łysiak-Szydłowska, B Rutkowski. Influence of predialysis oxidative stress on peroxidation processes after renal transplantation.
Transplantation proceedings.
2003 Sep; 35(6):2170-3. doi:
10.1016/s0041-1345(03)00767-x. [PMID: 14529878] - Nobuhiro Nakamoto, Shinichiro Tada, Kaori Kameyama, Kumi Kitamura, Satoshi Kurita, Yoshimasa Saito, Hidetsugu Saito, Hiromasa Ishii. A free radical scavenger, edaravone, attenuates steatosis and cell death via reducing inflammatory cytokine production in rat acute liver injury.
Free radical research.
2003 Aug; 37(8):849-59. doi:
10.1080/1071576031000136586. [PMID: 14567445] - Florian Schutt, Marion Bergmann, Frank G Holz, Jurgen Kopitz. Proteins modified by malondialdehyde, 4-hydroxynonenal, or advanced glycation end products in lipofuscin of human retinal pigment epithelium.
Investigative ophthalmology & visual science.
2003 Aug; 44(8):3663-8. doi:
10.1167/iovs.03-0172. [PMID: 12882821] - Philip C Burcham, Lisa M Kaminskas, Frank R Fontaine, Dennis R Petersen, Simon M Pyke. Aldehyde-sequestering drugs: tools for studying protein damage by lipid peroxidation products.
Toxicology.
2002 Dec; 181-182(?):229-36. doi:
10.1016/s0300-483x(02)00287-1. [PMID: 12505316] - C Loguercio, V De Girolamo, I de Sio, C Tuccillo, A Ascione, F Baldi, G Budillon, L Cimino, A Di Carlo, M P Di Marino, F Morisco, F Picciotto, L Terracciano, R Vecchione, V Verde, C Del Vecchio Blanco. Non-alcoholic fatty liver disease in an area of southern Italy: main clinical, histological, and pathophysiological aspects.
Journal of hepatology.
2001 Nov; 35(5):568-74. doi:
10.1016/s0168-8278(01)00192-1. [PMID: 11690701]