7-[2,5-Dihydroxy-2-[3-hydroxy-4-[3-(trifluoromethyl)phenoxy]but-1-enyl]cyclopentyl]hept-5-enoic acid (BioDeep_00000185402)

   

human metabolite blood metabolite


代谢物信息卡片


7-(2,5-dihydroxy-2-{3-hydroxy-4-[3-(trifluoromethyl)phenoxy]but-1-en-1-yl}cyclopentyl)hept-5-enoic acid

化学式: C23H29F3O6 (458.1916)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: OC(COC1=CC=CC(=C1)C(F)(F)F)C=CC1(O)CCC(O)C1CC=CCCCC(O)=O
InChI: InChI=1S/C23H29F3O6/c24-23(25,26)16-6-5-7-18(14-16)32-15-17(27)10-12-22(31)13-11-20(28)19(22)8-3-1-2-4-9-21(29)30/h1,3,5-7,10,12,14,17,19-20,27-28,31H,2,4,8-9,11,13,15H2,(H,29,30)

描述信息

同义名列表

4 个代谢物同义名

7-(2,5-dihydroxy-2-{3-hydroxy-4-[3-(trifluoromethyl)phenoxy]but-1-en-1-yl}cyclopentyl)hept-5-enoic acid; 7-[2,5-Dihydroxy-2-[3-hydroxy-4-[3-(trifluoromethyl)phenoxy]but-1-enyl]cyclopentyl]hept-5-enoic acid; 7-(2,5-Dihydroxy-2-{3-hydroxy-4-[3-(trifluoromethyl)phenoxy]but-1-en-1-yl}cyclopentyl)hept-5-enoate; 7-[2,5-Dihydroxy-2-[3-hydroxy-4-[3-(trifluoromethyl)phenoxy]but-1-enyl]cyclopentyl]hept-5-enoate



数据库引用编号

2 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表


文献列表

  • John Cuppoletti, Danuta H Malinowska, Kirti P Tewari, Jayati Chakrabarti, Ryuji Ueno. Unoprostone isopropyl and metabolite M1 activate BK channels and prevent ET-1-induced [Ca²⁺]i increases in human trabecular meshwork and smooth muscle. Investigative ophthalmology & visual science. 2012 Aug; 53(9):5178-89. doi: 10.1167/iovs.11-9046. [PMID: 22786902]
  • Gokce Topal, Nabil Foudi, B Sonmez Uydes-Dogan, Thierry Cachina, Mine Kucur, Altay Gezer, Riza Madazli, Osman Ozdemir, Xavier Norel. Involvement of prostaglandin F2α in preeclamptic human umbilical vein vasospasm: a role of prostaglandin F and thromboxane A2 receptors. Journal of hypertension. 2010 Dec; 28(12):2438-45. doi: 10.1097/hjh.0b013e32833e868f. [PMID: 20720498]
  • Jinshan Cao, Tatsuro Nakamura, Takio Kitazawa, Naoko Yamashiki, Tsubasa Yamamoto, Tetsuro Taneike. Characterization of prostanoid receptors present on adrenergic neurons innervating the porcine uterine longitudinal muscle. Prostaglandins & other lipid mediators. 2008 Jun; 86(1-4):26-34. doi: 10.1016/j.prostaglandins.2008.02.002. [PMID: 18403225]
  • K M Rice, S Uddemarri, D H Desai, R G Morrison, R Harris, G L Wright, E R Blough. PGF2alpha-associated vascular smooth muscle hypertrophy is ROS dependent and involves the activation of mTOR, p70S6k, and PTEN. Prostaglandins & other lipid mediators. 2008 Feb; 85(1-2):49-57. doi: 10.1016/j.prostaglandins.2007.10.009. [PMID: 18160324]
  • Victoria Seto, Christina Hirota, Simon Hirota, Luke J Janssen. E-Ring Isoprostanes Stimulate a Cl Conductance in Airway Epithelium via Prostaglandin E2-Selective Prostanoid Receptors. American journal of respiratory cell and molecular biology. 2008 Jan; 38(1):88-94. doi: 10.1165/rcmb.2007-0117oc. [PMID: 17673688]
  • Jinshan Cao, Munenori Yosida, Takio Kitazawa, Tetsuro Taneike. Uterine region-dependent differences in responsiveness to prostaglandins in the non-pregnant porcine myometrium. Prostaglandins & other lipid mediators. 2005 Jan; 75(1-4):105-22. doi: 10.1016/j.prostaglandins.2004.11.002. [PMID: 15789619]
  • B A McCue, M M Cason, M A Curtis, R D Faulkner, D C Dahlin. Determination of travoprost and travoprost free acid in human plasma by electrospray HPLC/MS/MS. Journal of pharmaceutical and biomedical analysis. 2002 Apr; 28(2):199-208. doi: 10.1016/s0731-7085(01)00644-6. [PMID: 11929662]
  • Najam A Sharif, Terry L Davis. Cloned human EP1 prostanoid receptor pharmacology characterized using radioligand binding techniques. The Journal of pharmacy and pharmacology. 2002 Apr; 54(4):539-47. doi: 10.1211/0022357021778655. [PMID: 11999132]
  • K Noguchi, H Endo, H Kondo, I Ishikawa. Prostaglandin F2alpha upregulates interleukin-6 production in human gingival fibroblasts. Journal of periodontal research. 2001 Apr; 36(2):80-7. doi: 10.1034/j.1600-0765.2001.360203.x. [PMID: 11327082]