6H-Oxazaphosphinine (BioDeep_00000185398)
human metabolite blood metabolite
代谢物信息卡片
化学式: C3H4NOP (101.0030504)
中文名称:
谱图信息:
最多检出来源 Homo sapiens(blood) 80%
分子结构信息
SMILES: C1C=CP=NO1
InChI: InChI=1S/C3H4NOP/c1-2-5-4-6-3-1/h1,3H,2H2
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- Mohamed M Sayed-Ahmed, Meshan Lafi Aldelemy, Mohamed M Hafez, Othman A Al-Shabanah. Inhibition of gene expression of organic cation/carnitine transporter and antioxidant enzymes in oxazaphosphorines-induced acute cardiomyopathic rat models.
Oxidative medicine and cellular longevity.
2012; 2012(?):452902. doi:
10.1155/2012/452902
. [PMID: 22701146] - Alain Deroussent, Stéphanie Rodriguez, Sonia Martelli, Atmane Seck, Estelle Dubus-Daudigeos, Didier Desmaële, Gilles Vassal, Angelo Paci. Quantification of dimethyl-ifosfamide and its N-deschloropropylated metabolites in mouse plasma by liquid chromatography-tandem mass spectrometry.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2011 Apr; 879(11-12):743-50. doi:
10.1016/j.jchromb.2011.02.012
. [PMID: 21377940] - William Weidong Du, Burton B Yang, Bing L Yang, Zhaoqun Deng, Ling Fang, Sze Wan Shan, Zina Jeyapalan, Yaou Zhang, Arun Seth, Albert J Yee. Versican G3 domain modulates breast cancer cell apoptosis: a mechanism for breast cancer cell response to chemotherapy and EGFR therapy.
PloS one.
2011; 6(11):e26396. doi:
10.1371/journal.pone.0026396
. [PMID: 22096483] - Yosef A Asiri. Probucol attenuates cyclophosphamide-induced oxidative apoptosis, p53 and Bax signal expression in rat cardiac tissues.
Oxidative medicine and cellular longevity.
2010 Sep; 3(5):308-16. doi:
10.4161/oxim.3.5.13107
. [PMID: 21150336] - Klaus Kümmerer, Ali Al-Ahmad. Estimation of the cancer risk to humans resulting from the presence of cyclophosphamide and ifosfamide in surface water.
Environmental science and pollution research international.
2010 Feb; 17(2):486-96. doi:
10.1007/s11356-009-0195-4
. [PMID: 19548016] - Abdulaziz A Al-Yahya, Abdulhakeem A Al-Majed, Ali M Gado, Mohammad H Daba, Othman A Al-Shabanah, Adel R A Abd-Allah. Acacia Senegal gum exudate offers protection against cyclophosphamide-induced urinary bladder cytotoxicity.
Oxidative medicine and cellular longevity.
2009 Sep; 2(4):207-13. doi:
10.4161/oxim.2.4.8878
. [PMID: 20716906] - Pradeep Tyagi, Vikas Tyagi, Naoki Yoshimura, Erich Witteemer, Derek Barclay, Patricia A Loughran, Ruben Zamora, Yoram Vodovotz. Gender-based reciprocal expression of transforming growth factor-beta1 and the inducible nitric oxide synthase in a rat model of cyclophosphamide-induced cystitis.
Journal of inflammation (London, England).
2009 Aug; 6(?):23. doi:
10.1186/1476-9255-6-23
. [PMID: 19691848] - Xufang Wang, Jinsong Zhang, Tongwen Xu. Thioredoxin reductase inactivation as a pivotal mechanism of ifosfamide in cancer therapy.
European journal of pharmacology.
2008 Jan; 579(1-3):66-73. doi:
10.1016/j.ejphar.2007.10.012
. [PMID: 18028906] - Mohammad Mohammadianpanah, Mehdi Shirazi, Ahmad Mosalaei, Shapour Omidvari, Niloofar Ahmadloo. Hemorrhagic cystitis in a patient receiving conventional doses of dacarbazine for metastatic malignant melanoma: case report and review of the literature.
Clinical therapeutics.
2007 Jun; 29(6):1161-5. doi:
10.1016/j.clinthera.2007.06.004
. [PMID: 17692730] - Ignaz J Buerge, Hans-Rudolf Buser, Thomas Poiger, Markus D Müller. Occurrence and fate of the cytostatic drugs cyclophosphamide and ifosfamide in wastewater and surface waters.
Environmental science & technology.
2006 Dec; 40(23):7242-50. doi:
10.1021/es0609405
. [PMID: 17180973] - Woo-Chan Son, Kenji Kamino, Yong-Soon Lee, Kyung-Sun Kang. Lack of effects of sodium 2-mercaptoethane sulfonate (mesna) on Ochratoxin A induced renal tumorigenicity following life-time oral administration of Ochratoxin A in DA and Lewis rats.
Toxicology letters.
2003 Apr; 142(1-2):19-27. doi:
10.1016/s0378-4274(02)00471-x
. [PMID: 12765235] - P S Schwartz, D J Waxman. Cyclophosphamide induces caspase 9-dependent apoptosis in 9L tumor cells.
Molecular pharmacology.
2001 Dec; 60(6):1268-79. doi:
10.1124/mol.60.6.1268
. [PMID: 11723234]