3-Methoxy-2-[(5-methylidene-4-pentylpyrrol-2-ylidene)methyl]-5-(1H-pyrrol-2-yl)-1H-pyrrole (BioDeep_00000185272)
human metabolite blood metabolite
代谢物信息卡片
4-methoxy-5-[(5-methylidene-4-pentyl-2,5-dihydro-1H-pyrrol-2-ylidene)methyl]-1H,1H-2,2-bipyrrole
化学式: C20H25N3O (323.199752)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CCCCCC1=CC(NC1=C)=CC1=C(OC)C=C(N1)C1=CC=CN1
InChI: InChI=1S/C20H25N3O/c1-4-5-6-8-15-11-16(22-14(15)2)12-19-20(24-3)13-18(23-19)17-9-7-10-21-17/h7,9-13,21-23H,2,4-6,8H2,1,3H3
相关代谢途径
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代谢反应
0 个相关的代谢反应过程信息。
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Plant Reactome(0)
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1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- A B Duzhak, Z I Panfilova, T G Duzhak, E A Vasyunina, M V Shternshis. Role of prodigiosin and chitinases in antagonistic activity of the bacterium Serratia marcescens against the fungus Didymella applanata.
Biochemistry. Biokhimiia.
2012 Aug; 77(8):910-6. doi:
10.1134/s0006297912080123. [PMID: 22860913] - Holger Meschke, Stefan Walter, Hildgund Schrempf. Characterization and localization of prodiginines from Streptomyces lividans suppressing Verticillium dahliae in the absence or presence of Arabidopsis thaliana.
Environmental microbiology.
2012 Apr; 14(4):940-52. doi:
10.1111/j.1462-2920.2011.02665.x. [PMID: 22151498] - Saraswoti Neupane, Nils Högberg, Sadhna Alström, Susan Lucas, James Han, Alla Lapidus, Jan-Fang Cheng, David Bruce, Lynne Goodwin, Sam Pitluck, Lin Peters, Galina Ovchinnikova, Megan Lu, Cliff Han, John C Detter, Roxanne Tapia, Anne Fiebig, Miriam Land, Loren Hauser, Nikos C Kyrpides, Natalia Ivanova, Ioanna Pagani, Hans-Peter Klenk, Tanja Woyke, Roger D Finlay. Complete genome sequence of the rapeseed plant-growth promoting Serratia plymuthica strain AS9.
Standards in genomic sciences.
2012 Mar; 6(1):54-62. doi:
10.4056/sigs.2595762. [PMID: 22675598] - Nabil M Wilf, George P C Salmond. The stationary phase sigma factor, RpoS, regulates the production of a carbapenem antibiotic, a bioactive prodigiosin and virulence in the enterobacterial pathogen Serratia sp. ATCC 39006.
Microbiology (Reading, England).
2012 Mar; 158(Pt 3):648-658. doi:
10.1099/mic.0.055780-0. [PMID: 22194349] - Sally J Gustafson, Kriya L Dunlap, Colin M McGill, Thomas B Kuhn. A nonpolar blueberry fraction blunts NADPH oxidase activation in neuronal cells exposed to tumor necrosis factor-α.
Oxidative medicine and cellular longevity.
2012; 2012(?):768101. doi:
10.1155/2012/768101. [PMID: 22530077] - Martha Ingrid Gutiérrez-Román, Francisco Holguín-Meléndez, Ricardo Bello-Mendoza, Karina Guillén-Navarro, Michael F Dunn, Graciela Huerta-Palacios. Production of prodigiosin and chitinases by tropical Serratia marcescens strains with potential to control plant pathogens.
World journal of microbiology & biotechnology.
2012 Jan; 28(1):145-53. doi:
10.1007/s11274-011-0803-6. [PMID: 22806790] - Lian-wei Xu, Lan Kluwe, Ting-ting Zhang, Sheng-nan Li, Yan-yan Mou, Zhen Sang, Jun Ma, Xiong Lu, Zhuo-jun Sun. Chinese herb mix Tiáo-Gēng-Tāng possesses antiaging and antioxidative effects and upregulates expression of estrogen receptors alpha and beta in ovariectomized rats.
BMC complementary and alternative medicine.
2011 Dec; 11(?):137. doi:
10.1186/1472-6882-11-137. [PMID: 22206438] - Borja Díaz de Greñu, Paulina Iglesias Hernández, Margarita Espona, David Quiñonero, Mark E Light, Tomás Torroba, Ricardo Pérez-Tomás, Roberto Quesada. Synthetic prodiginine obatoclax (GX15-070) and related analogues: anion binding, transmembrane transport, and cytotoxicity properties.
Chemistry (Weinheim an der Bergstrasse, Germany).
2011 Dec; 17(50):14074-83. doi:
10.1002/chem.201101547. [PMID: 22069220] - Nabil M Wilf, Neil R Williamson, Joshua P Ramsay, Simon Poulter, Kasia J Bandyra, George P C Salmond. The RNA chaperone, Hfq, controls two luxR-type regulators and plays a key role in pathogenesis and production of antibiotics in Serratia sp. ATCC 39006.
Environmental microbiology.
2011 Oct; 13(10):2649-66. doi:
10.1111/j.1462-2920.2011.02532.x. [PMID: 21824244] - Cally J E Haynes, Philip A Gale. Transmembrane anion transport by synthetic systems.
Chemical communications (Cambridge, England).
2011 Aug; 47(29):8203-9. doi:
10.1039/c1cc12061a. [PMID: 21594245] - Chia-Che Chang, Wei-Chuan Chen, Tsing-Fen Ho, Ho-Shing Wu, Yu-Hong Wei. Development of natural anti-tumor drugs by microorganisms.
Journal of bioscience and bioengineering.
2011 May; 111(5):501-11. doi:
10.1016/j.jbiosc.2010.12.026. [PMID: 21277252] - Philip A Gale. From anion receptors to transporters.
Accounts of chemical research.
2011 Mar; 44(3):216-26. doi:
10.1021/ar100134p. [PMID: 21207951] - Xiaoguang Liu, Jinli Jia, Roman Popat, Catherine A Ortori, Jun Li, Stephen P Diggle, Kexiang Gao, Miguel Cámara. Characterisation of two quorum sensing systems in the endophytic Serratia plymuthica strain G3: differential control of motility and biofilm formation according to life-style.
BMC microbiology.
2011 Feb; 11(1):26. doi:
10.1186/1471-2180-11-26. [PMID: 21284858] - Seong-Cheol Park, Jong-Kook Lee, Si Wouk Kim, Yoonkyung Park. Selective algicidal action of peptides against harmful algal bloom species.
PloS one.
2011; 6(10):e26733. doi:
10.1371/journal.pone.0026733. [PMID: 22046341] - Patrick D Schloss, Heather K Allen, Amy K Klimowicz, Christine Mlot, Jessica A Gross, Sarah Savengsuksa, Jennifer McEllin, Jon Clardy, Roger W Ruess, Jo Handelsman. Psychrotrophic strain of Janthinobacterium lividum from a cold Alaskan soil produces prodigiosin.
DNA and cell biology.
2010 Sep; 29(9):533-41. doi:
10.1089/dna.2010.1020. [PMID: 20626288] - Nobutaka Someya, Katsumi Akutsu. Indigenous bacteria may interfere with the biocontrol of plant diseases.
Die Naturwissenschaften.
2009 Jun; 96(6):743-7. doi:
10.1007/s00114-009-0524-y. [PMID: 19288072] - Jeffery T Davis, Philip A Gale, Oluyomi A Okunola, Pilar Prados, Jose Carlos Iglesias-Sánchez, Tomás Torroba, Roberto Quesada. Using small molecules to facilitate exchange of bicarbonate and chloride anions across liposomal membranes.
Nature chemistry.
2009 May; 1(2):138-44. doi:
10.1038/nchem.178. [PMID: 21378827] - Henrik Toft Simonsen, Damian Paul Drew, Christina Lunde. Perspectives on using physcomitrella patens as an alternative production platform for thapsigargin and other terpenoid drug candidates.
Perspectives in medicinal chemistry.
2009 Mar; 3(?):1-6. doi:
10.4137/pmc.s2220. [PMID: 19812738] - Dan Shu, Lei Chen, Weihua Wang, Zhenyu Yu, Cong Ren, Weiwen Zhang, Sheng Yang, Yinhua Lu, Weihong Jiang. afsQ1-Q2-sigQ is a pleiotropic but conditionally required signal transduction system for both secondary metabolism and morphological development in Streptomyces coelicolor.
Applied microbiology and biotechnology.
2009 Jan; 81(6):1149-60. doi:
10.1007/s00253-008-1738-1. [PMID: 18949475] - Ming Li, Tae-Jong Kim, Hyung-Jin Kwon, Joo-Won Suh. Effects of extracellular ATP on the physiology of Streptomyces coelicolor A3(2).
FEMS microbiology letters.
2008 Sep; 286(1):24-31. doi:
10.1111/j.1574-6968.2008.01248.x. [PMID: 18565122] - Tamzin Gristwood, Peter C Fineran, Lee Everson, George P C Salmond. PigZ, a TetR/AcrR family repressor, modulates secondary metabolism via the expression of a putative four-component resistance-nodulation-cell-division efflux pump, ZrpADBC, in Serratia sp. ATCC 39006.
Molecular microbiology.
2008 Jul; 69(2):418-35. doi:
10.1111/j.1365-2958.2008.06291.x. [PMID: 18485072] - Neil R Williamson, Peter C Fineran, Wakano Ogawa, Louise R Woodley, George P C Salmond. Integrated regulation involving quorum sensing, a two-component system, a GGDEF/EAL domain protein and a post-transcriptional regulator controls swarming and RhlA-dependent surfactant biosynthesis in Serratia.
Environmental microbiology.
2008 May; 10(5):1202-17. doi:
10.1111/j.1462-2920.2007.01536.x. [PMID: 18294208] - Takuji Nakashima, Takashi Iwashita, Tsuyoshi Fujita, Emiko Sato, Yoshimi Niwano, Masahiro Kohno, Shunsuke Kuwahara, Nobuyuki Harada, Satoshi Takeshita, Tatsuya Oda. A prodigiosin analogue inactivates NADPH oxidase in macrophage cells by inhibiting assembly of p47phox and Rac.
Journal of biochemistry.
2008 Jan; 143(1):107-15. doi:
10.1093/jb/mvm196. [PMID: 17965429] - Miguel A Matilla, Manuel Espinosa-Urgel, José J Rodríguez-Herva, Juan L Ramos, María Isabel Ramos-González. Genomic analysis reveals the major driving forces of bacterial life in the rhizosphere.
Genome biology.
2007; 8(9):R179. doi:
10.1186/gb-2007-8-9-r179. [PMID: 17784941] - Jennifer L Seganish, Jeffery T Davis. Prodigiosin is a chloride carrier that can function as an anion exchanger.
Chemical communications (Cambridge, England).
2005 Dec; ?(46):5781-3. doi:
10.1039/b511847f. [PMID: 16307144] - Yu-Hong Wei, Wei-Chuan Chen. Enhanced production of prodigiosin-like pigment from Serratia marcescens SMdeltaR by medium improvement and oil-supplementation strategies.
Journal of bioscience and bioengineering.
2005 Jun; 99(6):616-22. doi:
10.1263/jbb.99.616. [PMID: 16233840] - Hemangshu Podder, Barry D Kahan. Janus kinase 3: a novel target for selective transplant immunosupression.
Expert opinion on therapeutic targets.
2004 Dec; 8(6):613-29. doi:
10.1517/14728222.8.6.613. [PMID: 15584866] - A Fürstner, J Grabowski, C W Lehmann, T Kataoka, K Nagai. Synthesis and biological evaluation of nonylprodigiosin and macrocyclic prodigiosin analogues.
Chembiochem : a European journal of chemical biology.
2001 Jan; 2(1):60-8. doi:
10.1002/1439-7633(20010105)2:1<60::aid-cbic60>3.0.co;2-p. [PMID: 11828428]