(6-Aminoquinolin-2-yl) N-(2,5-dihydroxypyrrol-1-yl)-N-hydroxycarbamate (BioDeep_00000185203)
human metabolite blood metabolite
代谢物信息卡片
化学式: C14H12N4O5 (316.08076619999997)
中文名称:
谱图信息:
最多检出来源 Homo sapiens(blood) 50%
分子结构信息
SMILES: C1=CC2=C(C=CC(=N2)OC(=O)N(N3C(=CC=C3O)O)O)C=C1N
InChI: InChI=1S/C14H12N4O5/c15-9-2-3-10-8(7-9)1-4-11(16-10)23-14(21)18(22)17-12(19)5-6-13(17)20/h1-7,19-20,22H,15H2
描述信息
同义名列表
4 个代谢物同义名
1-[(6-aminoquinolin-2-yl)oxy]-N-(2,5-dihydroxy-1H-pyrrol-1-yl)-N-hydroxyformamide; 1-[(6-aminoquinolin-2-yl)oxy]-N-(2,5-dihydroxypyrrol-1-yl)-N-hydroxyformamide; (6-Aminoquinolin-2-yl) N-(2,5-dihydroxypyrrol-1-yl)-N-hydroxycarbamic acid; (6-Aminoquinolin-2-yl) N-(2,5-dihydroxypyrrol-1-yl)-N-hydroxycarbamate
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Bruce A Perkins, Naila Rabbani, Andrew Weston, Linda H Ficociello, Antonysunil Adaikalakoteswari, Monika Niewczas, James Warram, Andrzej S Krolewski, Paul Thornalley. Serum levels of advanced glycation endproducts and other markers of protein damage in early diabetic nephropathy in type 1 diabetes.
PloS one.
2012; 7(4):e35655. doi:
10.1371/journal.pone.0035655. [PMID: 22558190] - Yaguang Si, Hai Shi, Kyongbum Lee. Metabolic flux analysis of mitochondrial uncoupling in 3T3-L1 adipocytes.
PloS one.
2009 Sep; 4(9):e7000. doi:
10.1371/journal.pone.0007000. [PMID: 19746157] - Yoshifumi Nagumo, Kazuya Tanaka, Kaushal Tewari, Khwankaew Thiraporn, Toru Tsuchida, Toshimitsu Honma, Norikuni Ohtake, Kuni Sueyoshi, Yoshihiko Takahashi, Takuji Ohyama. Rapid quantification of cyanamide by ultra-high-pressure liquid chromatography in fertilizer, soil or plant samples.
Journal of chromatography. A.
2009 Jul; 1216(29):5614-8. doi:
10.1016/j.chroma.2009.05.067. [PMID: 19539296] - Shin Hosokawa, Katsunori Nakamura, Yukiyoshi Fujita, Ryuya Horiuchi, Koujirou Yamamoto. Determination of isepamicin in human plasma by HPLC with fluorescence detection after derivatization using 6-aminoquinolyl-N-hydroxysuccinimidyl-carbamate.
Biological & pharmaceutical bulletin.
2008 Oct; 31(10):1866-9. doi:
10.1248/bpb.31.1866. [PMID: 18827345] - Katalin Susztak, Emilio Ciccone, Peter McCue, Kumar Sharma, Erwin P Böttinger. Multiple metabolic hits converge on CD36 as novel mediator of tubular epithelial apoptosis in diabetic nephropathy.
PLoS medicine.
2005 Feb; 2(2):e45. doi:
10.1371/journal.pmed.0020045. [PMID: 15737001] - Naila Ahmed, Paul J Thornalley. Chromatographic assay of glycation adducts in human serum albumin glycated in vitro by derivatization with 6-aminoquinolyl-N-hydroxysuccinimidyl-carbamate and intrinsic fluorescence.
The Biochemical journal.
2002 May; 364(Pt 1):15-24. doi:
10.1042/bj3640015. [PMID: 11988071] - Naila Ahmed, Ognian K Argirov, Harjit S Minhas, Carlos A A Cordeiro, Paul J Thornalley. Assay of advanced glycation endproducts (AGEs): surveying AGEs by chromatographic assay with derivatization by 6-aminoquinolyl-N-hydroxysuccinimidyl-carbamate and application to Nepsilon-carboxymethyl-lysine- and Nepsilon-(1-carboxyethyl)lysine-modified albumin.
The Biochemical journal.
2002 May; 364(Pt 1):1-14. doi:
10.1042/bj3640001. [PMID: 11988070]